Search Results - (Author, Cooperation:P. Michon)
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1M. Manske ; O. Miotto ; S. Campino ; S. Auburn ; J. Almagro-Garcia ; G. Maslen ; J. O'Brien ; A. Djimde ; O. Doumbo ; I. Zongo ; J. B. Ouedraogo ; P. Michon ; I. Mueller ; P. Siba ; A. Nzila ; S. Borrmann ; S. M. Kiara ; K. Marsh ; H. Jiang ; X. Z. Su ; C. Amaratunga ; R. Fairhurst ; D. Socheat ; F. Nosten ; M. Imwong ; N. J. White ; M. Sanders ; E. Anastasi ; D. Alcock ; E. Drury ; S. Oyola ; M. A. Quail ; D. J. Turner ; V. Ruano-Rubio ; D. Jyothi ; L. Amenga-Etego ; C. Hubbart ; A. Jeffreys ; K. Rowlands ; C. Sutherland ; C. Roper ; V. Mangano ; D. Modiano ; J. C. Tan ; M. T. Ferdig ; A. Amambua-Ngwa ; D. J. Conway ; S. Takala-Harrison ; C. V. Plowe ; J. C. Rayner ; K. A. Rockett ; T. G. Clark ; C. I. Newbold ; M. Berriman ; B. MacInnis ; D. P. Kwiatkowski
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-06-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; *Biodiversity ; Genome, Protozoan ; Genotype ; *High-Throughput Nucleotide Sequencing ; Humans ; Malaria, Falciparum/*parasitology ; Phylogeny ; Plasmodium falciparum/classification/*genetics ; Polymorphism, Single Nucleotide ; Principal Component AnalysisPublished by: -
2Zhang, F., Zarkada, G., Han, J., Li, J., Dubrac, A., Ola, R., Genet, G., Boye, K., Michon, P., Künzel, S. E., Camporez, J. P., Singh, A. K., Fong, G.-H., Simons, M., Tso, P., Fernandez-Hernando, C., Shulman, G. I., Sessa, W. C., Eichmann, A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-08-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Biology, Medicine, DiseasesPublished by: -
3Dufour, P. ; Berard, J. ; Vinatier, D. ; Subtil, D. ; Guionet, B. ; Bourzoufi, K. ; Michon, P. ; Puech, F.
Springer
Published 1997Staff ViewISSN: 1432-0711Keywords: Key words: Myocardial infarction ; Coronary artery bypass graft ; Pre-pregnancy counselling ; PregnancySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract. The authors report a pregnancy in a 34 year old patient who previously experienced a myocardial infarction. The pregnancy ended at 39 weeks in the birth of a healthy girl weigthing 3040 g, by cesarean section under epidural anesthesia. A review of the literature revealed 33 similar cases, 16 of which were adequately documented.Type of Medium: Electronic ResourceURL: -
4Staff View
ISSN: 0040-6090Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
5Staff View
ISSN: 0040-6090Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0040-6090Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0040-6090Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1572-8943Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Zusammenfassung Die übliche Bestimmung kinetischer Parameter der Kristallisation amorpher Produkte basiert auf isothermen Messungen. Die Kristallisation von amorphem Selen in dünnen Schichten wird im allgemeinen in nicht-isothermen Experimenten (DTA) untersucht. Die Adaptation der Transformationsgeschwindigkeitsgleichung nach Avrami an die nicht-isotherme Kristallisation ermöglicht die Bestimmung verschiedener Kristallisationtypen. Dadurch wird es möglich, die Veränderungen der Wachstumsgeschwindigkeit und der Geschwindigkeit der Nukleation in Abhängigkeit von der Temperatur zu bestimmen. Der Einfluß der Wellenlänge bei der Bestrahlung während der Kristallisation auf diese Parameter wird ebenfalls untersucht.Abstract: Резюме Обычное определение кинетических параме тров кристаллизации амор фных продуктов основано н а изотермических изм ерениях. С помощью неизотермич еского метода (ДТА) изучена кристалл изация тонких аморфн ых пленок селена. Адаптация к не зотермической кристаллизации урав нения Аврами для скор ости превращения, позволи ло определить различные тичы крист аллизации, что в свою о чередь дало возможность опр еделить изменение скорости р оста и скорости образ ования центров кристаллиза ции от температуры. Также исследовано вл ияние на эти параметр ы длины волны света, использу емого для освещения во время кр исталлизации.Notes: Abstract The usual determination of kinetic parameters of crystallization of amorphous products is based on isothermal measurements. In general the crystallization of amorphous selenium thin films is studied by non-isothermal experiments (DTA). The adaptation to non-isothermal crystallization of the Avrami transformation rate equation allows us to determine different types of crystallization. These different regions enable one to determine the variations of the growth rate and of the nucleation rate versus temperature. The influence of the wavelength of illumination during the crystallization time on these parameters is also investigated.Type of Medium: Electronic ResourceURL: -
10Berthet, N. ; Boudali, A. ; Constant, J. F. ; Decout, J. L. ; Demeunynck, M. ; Fkyerat, A. ; Garcia, J. ; Laayoun, A. ; Michon, P. ; Lhomme, J.
Chicester [u.a.] : Wiley-Blackwell
Published 1994Staff ViewISSN: 0952-3499Keywords: Abasic sites ; Intercalation ; Endonuclease ; Chemistry ; Biochemistry and BiotechnologySource: Wiley InterScience Backfile Collection 1832-2000Topics: MedicineNotes: We have prepared a series of a tailor-made molecules that recognize and cleave DNA at apurinic sites in vitro. These molecules incorporate in their structure different units designed for specific function: an intercalator for DNA binding, an nucleic base for abasic site recognition and a linking chain of variable length and nature (including amino and/or amido functions). The cleavage efficiency of the molecules can be modulated by varying successively the nature of the intercalating agent, the nucleic base and the chain. All molecules bind to native calf thymus DNA with binding constants ranging from 104 to 106 M-1. Their cleavage activity was determined on plasmid DNA (pBR 322) containing 1.8 AP-sites per DNA-molecule. The minimum requirements for cleavage are the presence of the three units, the intercalator, the nucleic base and at least one amino function in the chain. The most efficient molecules cleaved plasmid DNA at nanomolar concentrations. Enzymatic experiments on the termini generated after cleavage of AP-DNA suggest a strand break induced by a β-elimination reaction. In order to get insight into the mode of action (efficiency, selectivity, interaction), we have used synthetic oligonucleotides containing either a true abasic site at a determined position to analyse the cleavage parameters of the synthetic molecules by HPLC or a chemically stable along (tetrahydrofuran) of the abasic site for high field 1H NMR spectrometry and footprinting experiments. All results are consistent with a β-elimination mechanism in which each constituent of the molecule exerts a specific function as indicated in the scheme: DNA targeting, abasic site nucleases and can be used advantageously as substitutes for the natural enzyme for in vitro cleavage of AP-sites containing DNA.Additional Material: 7 Ill.Type of Medium: Electronic ResourceURL: