Search Results - (Author, Cooperation:P. Michon)

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  1. 1
    M. Manske ; O. Miotto ; S. Campino ; S. Auburn ; J. Almagro-Garcia ; G. Maslen ; J. O'Brien ; A. Djimde ; O. Doumbo ; I. Zongo ; J. B. Ouedraogo ; P. Michon ; I. Mueller ; P. Siba ; A. Nzila ; S. Borrmann ; S. M. Kiara ; K. Marsh ; H. Jiang ; X. Z. Su ; C. Amaratunga ; R. Fairhurst ; D. Socheat ; F. Nosten ; M. Imwong ; N. J. White ; M. Sanders ; E. Anastasi ; D. Alcock ; E. Drury ; S. Oyola ; M. A. Quail ; D. J. Turner ; V. Ruano-Rubio ; D. Jyothi ; L. Amenga-Etego ; C. Hubbart ; A. Jeffreys ; K. Rowlands ; C. Sutherland ; C. Roper ; V. Mangano ; D. Modiano ; J. C. Tan ; M. T. Ferdig ; A. Amambua-Ngwa ; D. J. Conway ; S. Takala-Harrison ; C. V. Plowe ; J. C. Rayner ; K. A. Rockett ; T. G. Clark ; C. I. Newbold ; M. Berriman ; B. MacInnis ; D. P. Kwiatkowski
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-06-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alleles ; *Biodiversity ; Genome, Protozoan ; Genotype ; *High-Throughput Nucleotide Sequencing ; Humans ; Malaria, Falciparum/*parasitology ; Phylogeny ; Plasmodium falciparum/classification/*genetics ; Polymorphism, Single Nucleotide ; Principal Component Analysis
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-08-10
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Geosciences
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Cell Biology, Medicine, Diseases
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    ISSN:
    1432-0711
    Keywords:
    Key words: Myocardial infarction ; Coronary artery bypass graft ; Pre-pregnancy counselling ; Pregnancy
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract. The authors report a pregnancy in a 34 year old patient who previously experienced a myocardial infarction. The pregnancy ended at 39 weeks in the birth of a healthy girl weigthing 3040 g, by cesarean section under epidural anesthesia. A review of the literature revealed 33 similar cases, 16 of which were adequately documented.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    Grenet, J. ; Larmagnac, J.P. ; Michon, P. ; Vautier, C.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-6090
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Michon, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-6090
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Chow, Y.L. ; Michon, J. ; Michon, P. ; Morat, c. ; Rassat, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-4039
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Michon, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-6090
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Grenet, J. ; Larmagnac, J.P. ; Michon, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0040-6090
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Grenet, J. ; Larmagnac, J. P. ; Michon, P.
    Springer
    Published 1982
    Staff View
    ISSN:
    1572-8943
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Description / Table of Contents:
    Zusammenfassung Die übliche Bestimmung kinetischer Parameter der Kristallisation amorpher Produkte basiert auf isothermen Messungen. Die Kristallisation von amorphem Selen in dünnen Schichten wird im allgemeinen in nicht-isothermen Experimenten (DTA) untersucht. Die Adaptation der Transformationsgeschwindigkeitsgleichung nach Avrami an die nicht-isotherme Kristallisation ermöglicht die Bestimmung verschiedener Kristallisationtypen. Dadurch wird es möglich, die Veränderungen der Wachstumsgeschwindigkeit und der Geschwindigkeit der Nukleation in Abhängigkeit von der Temperatur zu bestimmen. Der Einfluß der Wellenlänge bei der Bestrahlung während der Kristallisation auf diese Parameter wird ebenfalls untersucht.
    Abstract:
    Резюме Обычное определение кинетических параме тров кристаллизации амор фных продуктов основано н а изотермических изм ерениях. С помощью неизотермич еского метода (ДТА) изучена кристалл изация тонких аморфн ых пленок селена. Адаптация к не зотермической кристаллизации урав нения Аврами для скор ости превращения, позволи ло определить различные тичы крист аллизации, что в свою о чередь дало возможность опр еделить изменение скорости р оста и скорости образ ования центров кристаллиза ции от температуры. Также исследовано вл ияние на эти параметр ы длины волны света, использу емого для освещения во время кр исталлизации.
    Notes:
    Abstract The usual determination of kinetic parameters of crystallization of amorphous products is based on isothermal measurements. In general the crystallization of amorphous selenium thin films is studied by non-isothermal experiments (DTA). The adaptation to non-isothermal crystallization of the Avrami transformation rate equation allows us to determine different types of crystallization. These different regions enable one to determine the variations of the growth rate and of the nucleation rate versus temperature. The influence of the wavelength of illumination during the crystallization time on these parameters is also investigated.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Berthet, N. ; Boudali, A. ; Constant, J. F. ; Decout, J. L. ; Demeunynck, M. ; Fkyerat, A. ; Garcia, J. ; Laayoun, A. ; Michon, P. ; Lhomme, J.

    Chicester [u.a.] : Wiley-Blackwell
    Published 1994
    Staff View
    ISSN:
    0952-3499
    Keywords:
    Abasic sites ; Intercalation ; Endonuclease ; Chemistry ; Biochemistry and Biotechnology
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Medicine
    Notes:
    We have prepared a series of a tailor-made molecules that recognize and cleave DNA at apurinic sites in vitro. These molecules incorporate in their structure different units designed for specific function: an intercalator for DNA binding, an nucleic base for abasic site recognition and a linking chain of variable length and nature (including amino and/or amido functions). The cleavage efficiency of the molecules can be modulated by varying successively the nature of the intercalating agent, the nucleic base and the chain. All molecules bind to native calf thymus DNA with binding constants ranging from 104 to 106 M-1. Their cleavage activity was determined on plasmid DNA (pBR 322) containing 1.8 AP-sites per DNA-molecule. The minimum requirements for cleavage are the presence of the three units, the intercalator, the nucleic base and at least one amino function in the chain. The most efficient molecules cleaved plasmid DNA at nanomolar concentrations. Enzymatic experiments on the termini generated after cleavage of AP-DNA suggest a strand break induced by a β-elimination reaction. In order to get insight into the mode of action (efficiency, selectivity, interaction), we have used synthetic oligonucleotides containing either a true abasic site at a determined position to analyse the cleavage parameters of the synthetic molecules by HPLC or a chemically stable along (tetrahydrofuran) of the abasic site for high field 1H NMR spectrometry and footprinting experiments. All results are consistent with a β-elimination mechanism in which each constituent of the molecule exerts a specific function as indicated in the scheme: DNA targeting, abasic site nucleases and can be used advantageously as substitutes for the natural enzyme for in vitro cleavage of AP-sites containing DNA.
    Additional Material:
    7 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses