Search Results - (Author, Cooperation:P. J. Wilson)

Showing 1 - 11 results of 11, query time: 0.25s Refine Results
  1. 1
    P. Bailey ; D. K. Chang ; K. Nones ; A. L. Johns ; A. M. Patch ; M. C. Gingras ; D. K. Miller ; A. N. Christ ; T. J. Bruxner ; M. C. Quinn ; C. Nourse ; L. C. Murtaugh ; I. Harliwong ; S. Idrisoglu ; S. Manning ; E. Nourbakhsh ; S. Wani ; L. Fink ; O. Holmes ; V. Chin ; M. J. Anderson ; S. Kazakoff ; C. Leonard ; F. Newell ; N. Waddell ; S. Wood ; Q. Xu ; P. J. Wilson ; N. Cloonan ; K. S. Kassahn ; D. Taylor ; K. Quek ; A. Robertson ; L. Pantano ; L. Mincarelli ; L. N. Sanchez ; L. Evers ; J. Wu ; M. Pinese ; M. J. Cowley ; M. D. Jones ; E. K. Colvin ; A. M. Nagrial ; E. S. Humphrey ; L. A. Chantrill ; A. Mawson ; J. Humphris ; A. Chou ; M. Pajic ; C. J. Scarlett ; A. V. Pinho ; M. Giry-Laterriere ; I. Rooman ; J. S. Samra ; J. G. Kench ; J. A. Lovell ; N. D. Merrett ; C. W. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; K. Moran-Jones ; N. B. Jamieson ; J. S. Graham ; F. Duthie ; K. Oien ; J. Hair ; R. Grutzmann ; A. Maitra ; C. A. Iacobuzio-Donahue ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; V. Corbo ; C. Bassi ; B. Rusev ; P. Capelli ; R. Salvia ; G. Tortora ; D. Mukhopadhyay ; G. M. Petersen ; D. M. Munzy ; W. E. Fisher ; S. A. Karim ; J. R. Eshleman ; R. H. Hruban ; C. Pilarsky ; J. P. Morton ; O. J. Sansom ; A. Scarpa ; E. A. Musgrove ; U. M. Bailey ; O. Hofmann ; R. L. Sutherland ; D. A. Wheeler ; A. J. Gill ; R. A. Gibbs ; J. V. Pearson ; A. V. Biankin ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2016
    Staff View
    Publication Date:
    2016-02-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Carcinoma, Pancreatic ; Ductal/classification/genetics/immunology/metabolism/pathology ; Cell Line, Tumor ; DNA Methylation ; DNA-Binding Proteins/genetics ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Genes, Neoplasm/*genetics ; Genome, Human/*genetics ; *Genomics ; Hepatocyte Nuclear Factor 3-beta/genetics ; Hepatocyte Nuclear Factor 3-gamma/genetics ; Histone Demethylases/genetics ; Homeodomain Proteins/genetics ; Humans ; Mice ; Mutation/*genetics ; Nuclear Proteins/genetics ; Pancreatic Neoplasms/*classification/*genetics/immunology/metabolism/pathology ; Prognosis ; Receptors, Cytoplasmic and Nuclear/genetics ; Survival Analysis ; Trans-Activators/genetics ; Transcription Factors/genetics ; Transcription, Genetic ; Transcriptome ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Proteins/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    A. M. Patch ; E. L. Christie ; D. Etemadmoghadam ; D. W. Garsed ; J. George ; S. Fereday ; K. Nones ; P. Cowin ; K. Alsop ; P. J. Bailey ; K. S. Kassahn ; F. Newell ; M. C. Quinn ; S. Kazakoff ; K. Quek ; C. Wilhelm-Benartzi ; E. Curry ; H. S. Leong ; A. Hamilton ; L. Mileshkin ; G. Au-Yeung ; C. Kennedy ; J. Hung ; Y. E. Chiew ; P. Harnett ; M. Friedlander ; M. Quinn ; J. Pyman ; S. Cordner ; P. O'Brien ; J. Leditschke ; G. Young ; K. Strachan ; P. Waring ; W. Azar ; C. Mitchell ; N. Traficante ; J. Hendley ; H. Thorne ; M. Shackleton ; D. K. Miller ; G. M. Arnau ; R. W. Tothill ; T. P. Holloway ; T. Semple ; I. Harliwong ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Idrisoglu ; T. J. Bruxner ; A. N. Christ ; B. Poudel ; O. Holmes ; M. Anderson ; C. Leonard ; A. Lonie ; N. Hall ; S. Wood ; D. F. Taylor ; Q. Xu ; J. L. Fink ; N. Waddell ; R. Drapkin ; E. Stronach ; H. Gabra ; R. Brown ; A. Jewell ; S. H. Nagaraj ; E. Markham ; P. J. Wilson ; J. Ellul ; O. McNally ; M. A. Doyle ; R. Vedururu ; C. Stewart ; E. Lengyel ; J. V. Pearson ; A. deFazio ; S. M. Grimmond ; D. D. Bowtell
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-05-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Cohort Studies ; Cyclin E/genetics ; Cystadenocarcinoma, Serous/drug therapy/genetics ; DNA Methylation ; DNA Mutational Analysis ; DNA-Binding Proteins/genetics ; Drug Resistance, Neoplasm/*drug effects/*genetics ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genes, Neurofibromatosis 1 ; Genome, Human/*genetics ; Germ-Line Mutation/genetics ; Humans ; Mutagenesis/genetics ; Oncogene Proteins/genetics ; Ovarian Neoplasms/drug therapy/*genetics ; P-Glycoprotein/genetics ; PTEN Phosphohydrolase/genetics ; Promoter Regions, Genetic/genetics ; Retinoblastoma Protein/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    A. M. Patch ; E. L. Christie ; D. Etemadmoghadam ; D. W. Garsed ; J. George ; S. Fereday ; K. Nones ; P. Cowin ; K. Alsop ; P. J. Bailey ; K. S. Kassahn ; F. Newell ; M. C. Quinn ; S. Kazakoff ; K. Quek ; C. Wilhelm-Benartzi ; E. Curry ; H. S. Leong ; A. Hamilton ; L. Mileshkin ; G. Au-Yeung ; C. Kennedy ; J. Hung ; Y. E. Chiew ; P. Harnett ; M. Friedlander ; M. Quinn ; J. Pyman ; S. Cordner ; P. O'Brien ; J. Leditschke ; G. Young ; K. Strachan ; P. Waring ; W. Azar ; C. Mitchell ; N. Traficante ; J. Hendley ; H. Thorne ; M. Shackleton ; D. K. Miller ; G. M. Arnau ; R. W. Tothill ; T. P. Holloway ; T. Semple ; I. Harliwong ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Idrisoglu ; T. J. Bruxner ; A. N. Christ ; B. Poudel ; O. Holmes ; M. Anderson ; C. Leonard ; A. Lonie ; N. Hall ; S. Wood ; D. F. Taylor ; Q. Xu ; J. L. Fink ; N. Waddell ; R. Drapkin ; E. Stronach ; H. Gabra ; R. Brown ; A. Jewell ; S. H. Nagaraj ; E. Markham ; P. J. Wilson ; J. Ellul ; O. McNally ; M. A. Doyle ; R. Vedururu ; C. Stewart ; E. Lengyel ; J. V. Pearson ; A. deFazio ; S. M. Grimmond ; D. D. Bowtell
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-10-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    N. Waddell ; M. Pajic ; A. M. Patch ; D. K. Chang ; K. S. Kassahn ; P. Bailey ; A. L. Johns ; D. Miller ; K. Nones ; K. Quek ; M. C. Quinn ; A. J. Robertson ; M. Z. Fadlullah ; T. J. Bruxner ; A. N. Christ ; I. Harliwong ; S. Idrisoglu ; S. Manning ; C. Nourse ; E. Nourbakhsh ; S. Wani ; P. J. Wilson ; E. Markham ; N. Cloonan ; M. J. Anderson ; J. L. Fink ; O. Holmes ; S. H. Kazakoff ; C. Leonard ; F. Newell ; B. Poudel ; S. Song ; D. Taylor ; S. Wood ; Q. Xu ; J. Wu ; M. Pinese ; M. J. Cowley ; H. C. Lee ; M. D. Jones ; A. M. Nagrial ; J. Humphris ; L. A. Chantrill ; V. Chin ; A. M. Steinmann ; A. Mawson ; E. S. Humphrey ; E. K. Colvin ; A. Chou ; C. J. Scarlett ; A. V. Pinho ; M. Giry-Laterriere ; I. Rooman ; J. S. Samra ; J. G. Kench ; J. A. Pettitt ; N. D. Merrett ; C. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; N. B. Jamieson ; J. S. Graham ; S. P. Niclou ; R. Bjerkvig ; R. Grutzmann ; D. Aust ; R. H. Hruban ; A. Maitra ; C. A. Iacobuzio-Donahue ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; V. Corbo ; C. Bassi ; M. Falconi ; G. Zamboni ; G. Tortora ; M. A. Tempero ; A. J. Gill ; J. R. Eshleman ; C. Pilarsky ; A. Scarpa ; E. A. Musgrove ; J. V. Pearson ; A. V. Biankin ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-02-27
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adenocarcinoma/drug therapy/genetics ; Animals ; Carcinoma, Pancreatic Ductal/drug therapy/genetics ; *DNA Mutational Analysis ; DNA Repair/genetics ; Female ; Genes, BRCA1 ; Genes, BRCA2 ; Genetic Markers/genetics ; Genome, Human/*genetics ; Genomic Instability/genetics ; *Genomics ; Genotype ; Humans ; Mice ; Mutation/*genetics ; Pancreatic Neoplasms/classification/drug therapy/*genetics ; Platinum/pharmacology ; Point Mutation/genetics ; Poly(ADP-ribose) Polymerase Inhibitors ; Xenograft Model Antitumor Assays
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    A. V. Biankin ; N. Waddell ; K. S. Kassahn ; M. C. Gingras ; L. B. Muthuswamy ; A. L. Johns ; D. K. Miller ; P. J. Wilson ; A. M. Patch ; J. Wu ; D. K. Chang ; M. J. Cowley ; B. B. Gardiner ; S. Song ; I. Harliwong ; S. Idrisoglu ; C. Nourse ; E. Nourbakhsh ; S. Manning ; S. Wani ; M. Gongora ; M. Pajic ; C. J. Scarlett ; A. J. Gill ; A. V. Pinho ; I. Rooman ; M. Anderson ; O. Holmes ; C. Leonard ; D. Taylor ; S. Wood ; Q. Xu ; K. Nones ; J. L. Fink ; A. Christ ; T. Bruxner ; N. Cloonan ; G. Kolle ; F. Newell ; M. Pinese ; R. S. Mead ; J. L. Humphris ; W. Kaplan ; M. D. Jones ; E. K. Colvin ; A. M. Nagrial ; E. S. Humphrey ; A. Chou ; V. T. Chin ; L. A. Chantrill ; A. Mawson ; J. S. Samra ; J. G. Kench ; J. A. Lovell ; R. J. Daly ; N. D. Merrett ; C. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; N. Kakkar ; F. Zhao ; Y. Q. Wu ; M. Wang ; D. M. Muzny ; W. E. Fisher ; F. C. Brunicardi ; S. E. Hodges ; J. G. Reid ; J. Drummond ; K. Chang ; Y. Han ; L. R. Lewis ; H. Dinh ; C. J. Buhay ; T. Beck ; L. Timms ; M. Sam ; K. Begley ; A. Brown ; D. Pai ; A. Panchal ; N. Buchner ; R. De Borja ; R. E. Denroche ; C. K. Yung ; S. Serra ; N. Onetto ; D. Mukhopadhyay ; M. S. Tsao ; P. A. Shaw ; G. M. Petersen ; S. Gallinger ; R. H. Hruban ; A. Maitra ; C. A. Iacobuzio-Donahue ; R. D. Schulick ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; P. Capelli ; V. Corbo ; M. Scardoni ; G. Tortora ; M. A. Tempero ; K. M. Mann ; N. A. Jenkins ; P. A. Perez-Mancera ; D. J. Adams ; D. A. Largaespada ; L. F. Wessels ; A. G. Rust ; L. D. Stein ; D. A. Tuveson ; N. G. Copeland ; E. A. Musgrove ; A. Scarpa ; J. R. Eshleman ; T. J. Hudson ; R. L. Sutherland ; D. A. Wheeler ; J. V. Pearson ; J. D. McPherson ; R. A. Gibbs ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-10-30
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Axons/*metabolism ; Carcinoma, Pancreatic Ductal/*genetics/*pathology ; Gene Dosage ; Gene Expression Regulation, Neoplastic ; Genome/*genetics ; Humans ; Kaplan-Meier Estimate ; Mice ; Mutation ; Pancreatic Neoplasms/*genetics/*pathology ; Proteins/genetics ; Signal Transduction
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    Badik, K. J., Jahner, J. P., Wilson, J. S.
    Royal Society
    Published 2018
    Staff View
    Publication Date:
    2018-03-22
    Publisher:
    Royal Society
    Electronic ISSN:
    2054-5703
    Topics:
    Natural Sciences in General
    Keywords:
    ecology, evolution
    Published by:
    http://royalsocietypublishing.org/

    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Wilson, P. J. ; Wood, C. M. ; Maina, J. N. ; White, B. N.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2000
    Staff View
    ISSN:
    1095-8649
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    The control region of the mitochondrial DNA haplotype frequencies were significantly different among the two separate lagoon populations of Oreochromis alcalicus grahami in Lake Magadi and of O. a. alcalicus from lake Natron, and DNA fingerprint similarity indices were significantly higher for intra-population comparisons of the two Magadi lagoon populations and the Lake Natron population than the inter-population similarity indices among these populations. A modified Fst measure indicated population sub-division and the phylogeographic partitioning of the VNTR fragments observed were unique to specific populations further indicating substantial genetic differentiation. The lagoon populations within Lake Magadi demonstrated the same degree of genetic differentiation as either of these populations did to the outgroup (the Lake Natron population). There appears to be limited gene flow between Lake Magadi tilapia populations and this population structure has important implications for protecting locally adapted populations within this unique ecosystem.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1095-8649.2000.tb00757.x

    Articles: DFG German National Licenses
  8. 8
    Forer, A. ; Wilson, P. J.
    Springer
    Published 1994
    Staff View
    ISSN:
    1615-6102
    Keywords:
    Chromosome movement ; Spindle fibres ; Mitosis ; Motor molecules ; Spindle matrix ; Ultraviolet microbeam
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Summary We present a new model for poleward chromosome movement during mitosis. The key points of the model are: (1) Kinetochore spindle fibres contain kinetochore microtubules linked to filaments; both the microtubules and the filaments are attached to the kinetochore. (2) Motor molecules which are fixed in a spindle matrix push poleward on the kinetochore microtubules in anaphase, and push on the associated filaments as well. (3) In addition to the kinetochore fibre pulling the kinetochore poleward, there are forces on the chromosomes themselves that push the chromosome arms poleward in anaphase; the forces on the chromosome arms are independent of the forces on the kinetochore spindle fibres and also may arise from motor molecules in the spindle matrix. (4) Kinetochore microtubules add subunits at the kinetochore and lose subunits from both the pole and the kinetochore; both polymerization and depolymerization are regulated by “compression” forces and by “stretching” forces on the microtubules themselves. Compression is caused by motor molecules pushing the kinetochore microtubules into the pole (during anaphase) or into the kinetochore (during prometaphase), and is caused by motor molecules pushing the chromosomes into the kinetochore fibres; stretching is caused by motor molecules pulling kinetochore microtubules out from the kinetochore. We view our model as a new way of looking at mitotic processes, with most details yet to be worked out, rather than as a detailed description of mitosis.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01403947

    Articles: DFG German National Licenses
  9. 9
    Hodgson, J. G. ; Halstead, P. ; Wilson, P. J. ; Davis, S.
    Springer
    Published 1999
    Staff View
    ISSN:
    1617-6278
    Keywords:
    Hay ; Meadow ; Pasture ; Archaeobotany ; Europe ; Farming history
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Archaeology
    Biology
    Notes:
    Abstract Hay malting and hay meadows have long been of fundamental ecological, economic and social importance in temperate Europe. A variety of archaeological sources suggests that hay making may date back to the Iron Age, but direct archaeobotanical evidence for this practice is problematic. Past grassland communities are imperfectly represented and preserved in archaeobotanical assemblages, and ancient meadow and pasture communities may not resemble present-day communities in terms of management practices or botanical composition. This paper explores the potential of ‘FIBS’ (Functional Interpretation of Botanical Surveys) in the archaeobotanical investigation of ancient grassland management. The botanical composition of present-day grassland communities was analysed in terms of functional attributes (e.g. canopy height) relevant to cutting, grazing and habitat productivity. The utility of these attributes for distinguishing between present-day meadow, pasture and unmanaged grassland communities has been evaluated. Similar analyses were performed on archaeobotanical data from Neolithic to post-Medieval northwestern and central Europe. Functional shifts over time, interpreted in the light of the functional analysis of modern grassland, suggest that hay-making was well established by the Iron Age. Avenues are suggested for the refinement and further development of the FIBS methodology in the archaeobotanical investigation of grassland management.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01291778

    Articles: DFG German National Licenses
  10. 10
    Bogaard, A. ; Hodgson, J. G. ; Wilson, P. J. ; Band, S. R.
    Springer
    Published 1998
    Staff View
    ISSN:
    1617-6278
    Keywords:
    Weed ecology ; Crop husbandry ; Soil productivity ; Functional attributes ; CSR strategy
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Archaeology
    Biology
    Notes:
    Abstract A method is presented for generating data on archaeological weed species relevant to soil productivity and consequently crop husbandry. Three plant attributes (maximum canopy height, maximum canopy spread and maximum dry leaf weight per node) which are functionally related to habitat productivity were measured for 161 British annual species. These three attributes were combined to produce an index of weed size. Index values were found to differ significantly between character species of phytosociological classes from fertile and infertile habitats and to provide an objective assessment of CSR (Competitor/Stress-tolerator/Ruderal) strategysensu Grime (1974, 1979). Further work is required, however, to distinguish ‘medium-sized’ species that exploit highly disturbed and productive habitats from those of less disturbed and less productive situations.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01393414

    Articles: DFG German National Licenses
  11. 11
    Wilson, P. J. ; Forer, A.

    New York, NY : Wiley-Blackwell
    Published 1989
    Staff View
    ISSN:
    0886-1544
    Keywords:
    mitosis ; spindle fibers ; cytoskeleton ; Life and Medical Sciences ; Cell & Developmental Biology
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Biology
    Medicine
    Notes:
    We studied the distribution of acetylated α-tubulin in the microtubules of spermatogenic cells from the crane fly Nephrotoma suturalis (Loew) using a mono-clonal antibody specific for acetylated α-tubulin (6-11B-1). We found that cells in all stages of spermatogenesis contained acetylated microtubules including primary spermatocytes, meiotic cells, spermatids, and sperm. A subset of the acety-lated microtubules (those in midbodies and flagella) were resistant to cold depolymerization. Newly polymerized microtubules in nondividing cells were not acetylated for up to 15 min. indicating that acetylation lagged behind polymerization. In spindles, newly polymerized microtubules were acetylated after 5 min. Antibodies to acetylated α-tubulin selectively stained chromosome-to-pole fibers in dividing cells, but the staining appeared to decrease and taper of at the kinetochores. This observation supports the hypothesis that tubulin subunits add at the kinetochore in metaphase and that acetylation occurs subsequent to addition. Further, this taper may be useful as a marker in anaphase, to distinguish between different hypotheses of chromosome motion.
    Additional Material:
    6 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1002/cm.970140210

    Articles: DFG German National Licenses