Search Results - (Author, Cooperation:P. J. Quesenberry)
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1Latest Papers from Table of Contents or Articles in PressW. Yang ; J. Wang ; D. C. Moore ; H. Liang ; M. Dooner ; Q. Wu ; R. Terek ; Q. Chen ; M. G. Ehrlich ; P. J. Quesenberry ; B. G. Neel
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-07-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Bone Neoplasms/drug therapy/genetics/*metabolism/*pathology ; Cartilage/metabolism/pathology ; Cathepsin K/deficiency/genetics/metabolism ; Cell Division ; Cell Lineage ; Chondromatosis/drug therapy/genetics/*metabolism/*pathology ; Exostoses, Multiple Hereditary/drug therapy/genetics/*metabolism/*pathology ; Fibroblast Growth Factors/metabolism ; Gene Deletion ; Gene Expression Regulation/drug effects ; Genes, Tumor Suppressor/physiology ; Hedgehog Proteins/antagonists & inhibitors/*metabolism ; MAP Kinase Signaling System ; Macrophages/metabolism ; Mesenchymal Stromal Cells/cytology/*metabolism ; Mice ; Mice, Knockout ; Mice, Transgenic ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors/metabolism ; Monocytes/metabolism ; Osteoclasts/metabolism ; Osteopetrosis/genetics/metabolism/pathology ; Parathyroid Hormone-Related Protein/metabolism ; Protein Tyrosine Phosphatase, Non-Receptor Type ; 11/*deficiency/genetics/metabolism ; *Signal Transduction/drug effectsPublished by: -
2Latest Papers from Table of Contents or Articles in PressChorzalska, A., Morgan, J., Ahsan, N., Treaba, D. O., Olszewski, A. J., Petersen, M., Kingston, N., Cheng, Y., Lombardo, K., Schorl, C., Yu, X., Zini, R., Pacilli, A., Tepper, A., Coburn, J., Hryniewicz-Jankowska, A., Zhao, T. C., Oancea, E., Reagan, J. L., Liang, O., Kotula, L., Quesenberry, P. J., Gruppuso, P. A., Manfredini, R., Vannucchi, A. M., Dubielecka, P. M.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-11-09Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Hematopoiesis and Stem Cells, Myeloid NeoplasiaPublished by: -
3Articles: DFG German National LicensesLarcher, C. ; McQuain, C. ; Berger, C. ; Mitterer, M. ; Quesenberry, P. J. ; Huemer, H. P. ; Knecht, H.
Springer
Published 1997Staff ViewISSN: 1432-0584Keywords: Key words Lymphocytosis ; Epstein-Barr virus ; LMP-1 ; LMP-2A ; KindredSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Epstein-Barr virus (EBV) genomes have been detected in peripheral blood lymphocytes (PBL) of patients with persistent polyclonal B-cell lymphocytosis (PPBL). This is consistent with the hypothesis that latent EBV infection is involved in the pathogenesis of this disorder. Two EBV-encoded proteins expressed in viral latency are the latent membrane proteins 1 and 2A (LMP1 and LMP2A). We have studied the LMP1 oncogene and the LMP2A gene in a female patient with PPBL and her five siblings. A cell line derived from peripheral blood lymphocytes (PBL) of the patient was also analyzed. A distinct 69-base pair deletion was identified within the carboxy terminal NF-κB activation domain of the LMP1 oncogene in PBL of the patient and in the cell line, whereas none of the siblings harbored this deletion. The tyrosine-signaling motif and the HLA A2.1 epitope of the LMP2A gene were wild type in the patient and all siblings. The presence of a 69-base pair deletion variant of the LMP1 oncogene within the lymphocytes of a PPBL patient but absence of this deletion variant in the unaffected siblings suggests a direct implication of altered LMP1 oncoprotein-dependent function in the pathogenesis of PPBL.Type of Medium: Electronic ResourceURL: