Search Results - (Author, Cooperation:P. Holliger)
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1V. B. Pinheiro ; A. I. Taylor ; C. Cozens ; M. Abramov ; M. Renders ; S. Zhang ; J. C. Chaput ; J. Wengel ; S. Y. Peak-Chew ; S. H. McLaughlin ; P. Herdewijn ; P. Holliger
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-04-21Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Aptamers, Nucleotide/*chemistry/genetics/*metabolism ; DNA/chemistry/genetics ; DNA-Directed DNA Polymerase/chemistry/genetics/metabolism ; Directed Molecular Evolution ; *Evolution, Molecular ; *Molecular Mimicry ; Nucleic Acids/*chemistry/genetics/metabolism ; Polymers/*chemistry/metabolism ; RNA/chemistry/genetics ; RNA-Directed DNA Polymerase/chemistry/metabolism ; Reverse Transcription ; Templates, Genetic ; Transcription, GeneticPublished by: -
2A. I. Taylor ; V. B. Pinheiro ; M. J. Smola ; A. S. Morgunov ; S. Peak-Chew ; C. Cozens ; K. M. Weeks ; P. Herdewijn ; P. Holliger
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-12-04Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; Catalysis ; Endonucleases/metabolism ; Ligases/metabolism ; Nucleic Acids/*chemical synthesis/chemistry/*metabolism ; Polymers/*chemical synthesis/*chemistry/metabolism ; RNA/metabolismPublished by: -
3A. Wochner ; J. Attwater ; A. Coulson ; P. Holliger
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-04-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; Biocatalysis ; Directed Molecular Evolution ; Genetic Engineering ; Mutation ; Nucleic Acid Conformation ; RNA/*chemistry/genetics/metabolism ; RNA Replicase/*chemistry/genetics/*metabolism ; RNA, Catalytic/*chemistry/genetics/*metabolism ; Selection, Genetic ; Templates, Genetic ; *Transcription, GeneticPublished by: -
4Staff View
Publication Date: 2012-10-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: *Biocatalysis ; *Evolution, Chemical ; *Models, Biological ; *Origin of Life ; RNA, Catalytic/*biosynthesis/*metabolismPublished by: -
5Staff View
ISSN: 0012-821XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeosciencesPhysicsType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 0014-5793Keywords: Active site site-directed mutagenesis ; Bovine pancreatic ribonuclease ; Catalytic antisense oligonucleotide ; Synthetic geneSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0012-821XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeosciencesPhysicsType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0012-821XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: GeosciencesPhysicsType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 0958-1669Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineProcess Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: -
10Nagy, Bartholomew ; Gauthier-Lafaye, F. ; Holliger, P. ; Davis, D. W. ; Mossman, David J. ; Leventhal, Joel S. ; Rigali, Mark J. ; Parnell, John
[s.l.] : Nature Publishing Group
Published 1991Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Small pockets of uranium ore at Oklo went critical 1,95F0± 30 Myr ago6, producing several natural fission reactors. Reactors 1-6 contain virtually no organic matter. Total energy production in these reactors was 16,500 MWyr. Roughly 6 tons of 235U fissioned; the total uranium ...Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1432-0851Keywords: Key words Diabodies ; Bispecific antibodies ; Bispecific antibody fragmentsSource: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1432-1866Source: Springer Online Journal Archives 1860-2000Topics: GeosciencesNotes: Abstract A La-Ce-Sr-Ca aluminous hydroxy phosphate of the goyazite-florencite-crandallite series was observed in the nuclear reactor zone 13 in the Oklo uranium deposit (Gabon). It has a trigonal elementary cell with a = 6.98 ± 0.03 Å and c = 16.35 ± 0.04 Å (space group P3m). It occurs in a U-rich sample depleted in 235U (235U/238U = 0.0047). Its chemical composition, measured by ion microprobe analyses, shows that it contains fission products (Zr, LREE) whereas the isotopic composition of Ba and Sr is natural. Ion microprobe imaging indicates that the nearby uraninite crystals are depleted in fissiogenic LREE. This study shows that the migration of some fission products, probably related to a dolerite dike intrusion, is limited by the formation of aluminous hydroxy phosphates.Type of Medium: Electronic ResourceURL: