Search Results - (Author, Cooperation:P. H. Lee)
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1D. P. Hibar ; J. L. Stein ; M. E. Renteria ; A. Arias-Vasquez ; S. Desrivieres ; N. Jahanshad ; R. Toro ; K. Wittfeld ; L. Abramovic ; M. Andersson ; B. S. Aribisala ; N. J. Armstrong ; M. Bernard ; M. M. Bohlken ; M. P. Boks ; J. Bralten ; A. A. Brown ; M. M. Chakravarty ; Q. Chen ; C. R. Ching ; G. Cuellar-Partida ; A. den Braber ; S. Giddaluru ; A. L. Goldman ; O. Grimm ; T. Guadalupe ; J. Hass ; G. Woldehawariat ; A. J. Holmes ; M. Hoogman ; D. Janowitz ; T. Jia ; S. Kim ; M. Klein ; B. Kraemer ; P. H. Lee ; L. M. Olde Loohuis ; M. Luciano ; C. Macare ; K. A. Mather ; M. Mattheisen ; Y. Milaneschi ; K. Nho ; M. Papmeyer ; A. Ramasamy ; S. L. Risacher ; R. Roiz-Santianez ; E. J. Rose ; A. Salami ; P. G. Samann ; L. Schmaal ; A. J. Schork ; J. Shin ; L. T. Strike ; A. Teumer ; M. M. van Donkelaar ; K. R. van Eijk ; R. K. Walters ; L. T. Westlye ; C. D. Whelan ; A. M. Winkler ; M. P. Zwiers ; S. Alhusaini ; L. Athanasiu ; S. Ehrlich ; M. M. Hakobjan ; C. B. Hartberg ; U. K. Haukvik ; A. J. Heister ; D. Hoehn ; D. Kasperaviciute ; D. C. Liewald ; L. M. Lopez ; R. R. Makkinje ; M. Matarin ; M. A. Naber ; D. R. McKay ; M. Needham ; A. C. Nugent ; B. Putz ; N. A. Royle ; L. Shen ; E. Sprooten ; D. Trabzuni ; S. S. van der Marel ; K. J. van Hulzen ; E. Walton ; C. Wolf ; L. Almasy ; D. Ames ; S. Arepalli ; A. A. Assareh ; M. E. Bastin ; H. Brodaty ; K. B. Bulayeva ; M. A. Carless ; S. Cichon ; A. Corvin ; J. E. Curran ; M. Czisch ; G. I. de Zubicaray ; A. Dillman ; R. Duggirala ; T. D. Dyer ; S. Erk ; I. O. Fedko ; L. Ferrucci ; T. M. Foroud ; P. T. Fox ; M. Fukunaga ; J. R. Gibbs ; H. H. Goring ; R. C. Green ; S. Guelfi ; N. K. Hansell ; C. A. Hartman ; K. Hegenscheid ; A. Heinz ; D. G. Hernandez ; D. J. Heslenfeld ; P. J. Hoekstra ; F. Holsboer ; G. Homuth ; J. J. Hottenga ; M. Ikeda ; C. R. Jack, Jr. ; M. Jenkinson ; R. Johnson ; R. Kanai ; M. Keil ; J. W. Kent, Jr. ; P. Kochunov ; J. B. Kwok ; S. M. Lawrie ; X. Liu ; D. L. Longo ; K. L. McMahon ; E. Meisenzahl ; I. Melle ; S. Mohnke ; G. W. Montgomery ; J. C. Mostert ; T. W. Muhleisen ; M. A. Nalls ; T. E. Nichols ; L. G. Nilsson ; M. M. Nothen ; K. Ohi ; R. L. Olvera ; R. Perez-Iglesias ; G. B. Pike ; S. G. Potkin ; I. Reinvang ; S. Reppermund ; M. Rietschel ; N. Romanczuk-Seiferth ; G. D. Rosen ; D. Rujescu ; K. Schnell ; P. R. Schofield ; C. Smith ; V. M. Steen ; J. E. Sussmann ; A. Thalamuthu ; A. W. Toga ; B. J. Traynor ; J. Troncoso ; J. A. Turner ; M. C. Valdes Hernandez ; D. van 't Ent ; M. van der Brug ; N. J. van der Wee ; M. J. van Tol ; D. J. Veltman ; T. H. Wassink ; E. Westman ; R. H. Zielke ; A. B. Zonderman ; D. G. Ashbrook ; R. Hager ; L. Lu ; F. J. McMahon ; D. W. Morris ; R. W. Williams ; H. G. Brunner ; R. L. Buckner ; J. K. Buitelaar ; W. Cahn ; V. D. Calhoun ; G. L. Cavalleri ; B. Crespo-Facorro ; A. M. Dale ; G. E. Davies ; N. Delanty ; C. Depondt ; S. Djurovic ; W. C. Drevets ; T. Espeseth ; R. L. Gollub ; B. C. Ho ; W. Hoffmann ; N. Hosten ; R. S. Kahn ; S. Le Hellard ; A. Meyer-Lindenberg ; B. Muller-Myhsok ; M. Nauck ; L. Nyberg ; M. Pandolfo ; B. W. Penninx ; J. L. Roffman ; S. M. Sisodiya ; J. W. Smoller ; H. van Bokhoven ; N. E. van Haren ; H. Volzke ; H. Walter ; M. W. Weiner ; W. Wen ; T. White ; I. Agartz ; O. A. Andreassen ; J. Blangero ; D. I. Boomsma ; R. M. Brouwer ; D. M. Cannon ; M. R. Cookson ; E. J. de Geus ; I. J. Deary ; G. Donohoe ; G. Fernandez ; S. E. Fisher ; C. Francks ; D. C. Glahn ; H. J. Grabe ; O. Gruber ; J. Hardy ; R. Hashimoto ; H. E. Hulshoff Pol ; E. G. Jonsson ; I. Kloszewska ; S. Lovestone ; V. S. Mattay ; P. Mecocci ; C. McDonald ; A. M. McIntosh ; R. A. Ophoff ; T. Paus ; Z. Pausova ; M. Ryten ; P. S. Sachdev ; A. J. Saykin ; A. Simmons ; A. Singleton ; H. Soininen ; J. M. Wardlaw ; M. E. Weale ; D. R. Weinberger ; H. H. Adams ; L. J. Launer ; S. Seiler ; R. Schmidt ; G. Chauhan ; C. L. Satizabal ; J. T. Becker ; L. Yanek ; S. J. van der Lee ; M. Ebling ; B. Fischl ; W. T. Longstreth, Jr. ; D. Greve ; H. Schmidt ; P. Nyquist ; L. N. Vinke ; C. M. van Duijn ; L. Xue ; B. Mazoyer ; J. C. Bis ; V. Gudnason ; S. Seshadri ; M. A. Ikram ; N. G. Martin ; M. J. Wright ; G. Schumann ; B. Franke ; P. M. Thompson ; S. E. Medland
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-01-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aging/genetics ; Apoptosis/genetics ; Brain/*anatomy & histology ; Caudate Nucleus/anatomy & histology ; Child ; Female ; Gene Expression Regulation, Developmental/genetics ; Genetic Loci/genetics ; Genetic Variation/*genetics ; *Genome-Wide Association Study ; Hippocampus/anatomy & histology ; Humans ; Magnetic Resonance Imaging ; Male ; Membrane Proteins/genetics ; Middle Aged ; Organ Size/genetics ; Putamen/anatomy & histology ; Sex Characteristics ; Skull/anatomy & histology ; Young AdultPublished by: -
2C. J. Magnus ; P. H. Lee ; D. Atasoy ; H. H. Su ; L. L. Looger ; S. M. Sternson
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-09-03Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Benzamides/chemistry/metabolism/pharmacology ; Bicyclo Compounds/chemistry/metabolism/pharmacology ; Brain/cytology/physiology ; Feeding Behavior ; Female ; HEK293 Cells ; Humans ; Ion Channel Gating ; Ligand-Gated Ion Channels/chemistry/*genetics/*metabolism ; Ligands ; Membrane Potentials ; Mice ; Mice, Inbred C57BL ; Mutagenesis ; Neurons/*physiology ; Patch-Clamp Techniques ; Protein Binding ; *Protein Engineering ; Protein Structure, Tertiary ; Quinuclidines/chemistry/metabolism/pharmacology ; Receptors, Glycine/genetics/metabolism ; Receptors, Nicotinic/chemistry/genetics/metabolism ; Receptors, Serotonin, 5-HT3/genetics/metabolism ; Recombinant Fusion Proteins/chemistry/metabolism ; Small Molecule Libraries ; Stereoisomerism ; alpha7 Nicotinic Acetylcholine ReceptorPublished by: -
3Kang, D.-Y., Ahn, J.-M., Kim, Y. W., Moon, J. Y., Lee, J. S., Koo, B.-K., Lee, P. H., Park, D.-W., Kang, S.-J., Lee, S.-W., Kim, Y.-H., Park, S.-W., Park, S.-J.
American Heart Association (AHA)
Published 2018Staff ViewPublication Date: 2018-06-20Publisher: American Heart Association (AHA)Print ISSN: 1941-9651Electronic ISSN: 1942-0080Topics: MedicineKeywords: Angiography, UltrasoundPublished by: -
4Staff View
Publication Date: 2018-06-22Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Genetics, Medicine, Diseases, Online OnlyPublished by: -
5Staff View
Publication Date: 2018-04-14Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Research methodsPublished by: -
6Barter, J. D. ; Beach, K. L. ; Lee, P. H. Y.
[S.l.] : American Institute of Physics (AIP)
Published 1993Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: We demonstrate by experiment that, in addition to the local surface slope, local surface elevation can also be directly measured using the refracted light beam traversing an air-water interface, thus showing the feasibility of a new surface slope and wave height amplitude gauge for use in studying water waves. We have achieved surface height resolutions as small as 40 μm for the range of surface wavelengths λ∼1.2–2.4 cm used in the present experiments. This measurement principle is readily adaptable to waves of different scale. The available dynamic range defined by the ratio of maximum wave amplitude to minimum resolvable amplitude need only be limited by the useful dynamic range of the photodetector when matched to a laser of suitable frequency and sufficient power.Type of Medium: Electronic ResourceURL: -
7Lee, P. H. A. ; Harris, S. M. ; Zhang, L. ; Falla, T. J. ; Gallo, R. L.
Oxford, UK; Malden, USA : Blackwell Science Ltd/Inc.
Published 2004Staff ViewISSN: 1524-475XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Intact skin represents the first line of defense against microbial pathogens. Effectors of innate immunity such as antimicrobial peptides are important when this barrier is breached due to infection or injury. Antimicrobial peptides can kill microbes directly, however several investigations have suggested they can also modify host cell behaviors to promote wound repair. It is unclear whether the ability of these molecules to positively influence wound repair is dependent on their antimicrobial function or on their ability to influence the host. To investigate this, the microbial killing capacity of specific antimicrobial peptide fragments was determined and compared with their ability to affect wound repair in a murine model of aseptic full-thickness excisional injury. HB-107, a peptide fragment derived from Cecropin B, lacks antimicrobial activity yet showed up to 64% improvement in wound closure at day13 when compared to either scrambled peptide or vehicle controls. This effect was comparable to that seen after treatment with currently accepted therapy. Histological evaluation of wounds treated with HB-107 displayed keratinocyte hyperplasia and increased leukocyte infiltration compared to controls. To explore the mechanism for these findings, we tested the ability of HB-107 to stimulate IL-8 secretion. HB-107 peptide was able to stimulate IL-8 release from cultured dermal microvascular endothelial cells when compared to scrambled peptide control or other peptides derived from Cecropin B. Taken together, this data confirms that antimicrobial peptides can function as important effectors of wound repair independent of antimicrobial function.Type of Medium: Electronic ResourceURL: -
8Lee, P. H. Y. ; Price, R. H. ; Reay, J. ; Pecos, J. ; Seagrave, J. ; McGurn, J. ; Cochrane, B. ; Anderson, B.
[S.l.] : American Institute of Physics (AIP)
Published 1986Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The Trailmaster/Pioneer 1 series of imploding plasma experiments are aimed at using an inductive storage driver to implode an ultrathin aluminum foil with a multimegampere, submicrosecond electrical pulse. The power pulse is produced by an explosive flux compression generator and a fast plasma compression opening switch. The goal is to obtain an intense source of soft x rays from the thermalization of the plasma kinetic energy when pinch occurs on axis. An important target diagnostic is a fast camera which measures the dynamics of foil run-in and implosion symmetry. These measurements are made in the visible, UV, and x-ray portions of the electromagnetic spectrum. UV/x-ray images are first converted to visible light, then transmitted by visible light optics to a framing camera, which is located at a safe distance. For UV/soft x-ray imaging, we mount a disposable pinhole camera with a p-terphenyl-coated converter screen on the target chamber. For soft/hard x-ray imaging, a microchannel plate is used in front of the p-terphenyl-coated screen to boost quantum detection efficiency and signal gain. For faster temporal response the p-terphenyl can be replaced by NE-111 or other fast fluors. Image transmission is accomplished by means of two large mirrors (150–250 mm diam) and a large catadioptric telescope. The framing camera consists of four gated microchannel plates with adjustable gate and interframe times. The framing camera is a versatile and rugged instrument, it has performed satisfactorily for each and every Pioneer shot. Experimental data indicate that this camera, which uses individual gated microchannel plates, is far superior to commercial streak/framing cameras, because it has a dynamic range which is orders of magnitude larger than commercial cameras, each channel can be attenuated separately, further increasing the dynamic range of the imaging system. This makes our framing camera especially suitable for recording sequences of events where the brightness changes by many orders of magnitude. This work was performed under the auspices of U.S. DOE.Type of Medium: Electronic ResourceURL: -
9Lee, P. H. Y. ; Price, R. H. ; Reay, J. ; Pecos, J. ; Seagrave, J. ; McGurn, J. ; Cochrane, B. ; Anderson, B.
[S.l.] : American Institute of Physics (AIP)
Published 1986Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: We report on a fast framing camera designed to image imploding foils driven by inductive storage drivers. The camera has several front ends which are disposable, they allow for imaging in either the visible, UV, or x-ray regions; it also has very large dynamic range which allows it to record sequences of events where the brightness changes by many orders of magnitude.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We describe a method for the direct, absolute and noninvasive measurement of surface height profiles on air-liquid interfaces. Wave amplitude spectra are directly obtained from electronically imaged surface height profiles without resorting to problematic reconstructions from wave slope measurements. This measurement principle relies on the volume attenuation of light in the liquid rather than the refraction of light at the wave-supporting interface. Surface height resolution of tens of micrometers has been demonstrated. A suitable photodiode detector and an appropriate laser provide the two parameters which are sufficient to optimize system spatial and temporal resolution and spatial dynamic range.Type of Medium: Electronic ResourceURL: -
11Wang, L. ; Lee, P. H. Y. ; Barter, J. D. ; Caponi, M.
Woodbury, NY : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: We have developed a model for electromagnetic wave propagation in and scattering from random media. Scattering potentials are introduced to account for the reflections and refractions from boundaries. The differential cross sections for backscatter are calculated in the Kirchhoff approximation. We find that, in single scattering processes, the polarizations of differential cross sections are conserved and the differential cross sections are independent of the polarizations. The cross-polarized differential cross sections are symmetric and solely attributed to multi-scattering processes. Our results are in good agreement with experimental measurements. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1440-1681Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: 1. Male rats were treated with a fixed dose of aminoglutethimide (50 mg/kg s.c.) or with progressively increasing doses (50-100 mg/kg s.c.) for 3 days. Corticosterone levels were found to be decreased in the latter group. Platelet uptake of serotonin as well as the apparent Vmax were decreased, whereas the Km of uptake were increased when compared with that of the control group.2. Addition of ACTH (10 iu/dl) to control rat platelet and corticosterone (10-80 μg/dl) or triamcinolone (0.5-5.0 μg/dl) to adrenalectomized rat platelet suspension in vitro did not increase the serotonin uptake of the preparation.3. Administration of exogenous dexamethasone (0.05-0.2 mg/kg i.m.) or triamcinolone (0.05-5.0 mg/kg i.m.) to adrenalectomized rats, caused a dose related increase in active uptake of serotonin by the platelets. Deoxycorticosterone (0.1-1.0 mg/kg i.m.) did not have this effect.4. The time course of response to, and the maximum percentage increase in platelet serotonin uptake by, exogenous corticosteroids are related to their glucocorticoid potency.5. The possible role of glucocorticoids on platelet serotonin uptake process is discussed.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1440-1681Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: 1. Changes induced by adrenalectomy, triamcinolone treatment and deoxycorticosterone (DOC) treatment on the uptake of [3H]-serotonin into platelets were studied ex vivo, using rat platelets suspended in physiological medium.2. Adrenalectomy caused a decrease in active uptake of serotonin and an associated increase in apparent Km.3. Treatment of the adrenalectomized rats with triamcinolone (0.25 mg/kg), but not DOC (1.0 mg/kg) restored the active uptake of serotonin.4. At triamcinolone dose of 0.5 mg/kg, the serotonin uptake was raised to a level that was significantly higher than normal.5. Kinetic analysis of uptake data showed the apparent Km, to be affected by both triamcinolone and DOC, while the apparent Vmax of uptake rate was increased by triamcinolone treatment.Type of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0028-3932Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PsychologyType of Medium: Electronic ResourceURL: -
15Seka, W. ; Goldman, L. M. ; Soures, J. M. ; Craxton, R. S. ; Boehly, T. ; Keck, R. L. ; Tanaka, K. ; Boni, R. ; Yaakobi, B. ; Bingham, R. ; Williams, E. ; Dreyfus, R. W. ; Bogen, P. ; Langer, H. ; Baldis, H. A. ; Walsh, C. J. ; Zhi-zhan, Xu ; Yu-guang, Xu ; Guang-yu, Yin ; Yan-zhen, Zhang ; Jiajin, Yu ; Lee, P. H. Y. ; Eldmann, K. ; Maaswinkel, A. G. M. ; Sigel, R.
Springer
Published 1982Staff ViewISSN: 1432-0649Keywords: 50 ; 34 ; 32.50 ; 42.60 ; 61.80 ; 62 ; 42.65Source: Springer Online Journal Archives 1860-2000Topics: PhysicsType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1432-2218Keywords: Laparoscopic cholecystectomy ; Cirrhosis of liver ; Complication ; HemorrhageSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Laparoscopic cholecystectomy was performed in a cirrhotic patient who had cholelithiasis. Despite the existence of coagulopathy, excessive bleeding from the gallbladder and nodular liver was avoidable. Dissection and extraction of the gallbladder went smoothly. However, serious bleeding from the trocar site occurred following the withdrawal of the trocar/cannula. The bleeding was not controllable by electrocauterization. A novel attempt using a transmural suture technique was tried, and hemostasis was achieved satisfactorily. Our patient enjoyed an uneventful postoperative recovery and was discharged 2 days after surgery.Type of Medium: Electronic ResourceURL: