Search Results - (Author, Cooperation:P. Greengard)

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  1. 1
    Staff View
    Publication Date:
    2013-07-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Asphyxia/*chemically induced/mortality ; Hospitalization/statistics & numerical data ; *Human Rights ; Humans ; Tear Gases/*toxicity ; Turkey ; Violence/*prevention & control ; Wounds and Injuries/etiology/mortality
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    C. L. Tan ; J. L. Plotkin ; M. T. Veno ; M. von Schimmelmann ; P. Feinberg ; S. Mann ; A. Handler ; J. Kjems ; D. J. Surmeier ; D. O'Carroll ; P. Greengard ; A. Schaefer
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-12-07
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Corpus Striatum/cytology ; Dendrites/physiology ; Epilepsy/metabolism ; Hyperkinesis/metabolism ; MAP Kinase Signaling System ; Mice ; MicroRNAs/genetics/*metabolism ; Mitogen-Activated Protein Kinase 1/antagonists & inhibitors/metabolism ; Mitogen-Activated Protein Kinase 3/antagonists & inhibitors/metabolism ; *Motor Activity ; Neurons/*physiology ; Parkinsonian Disorders/metabolism/physiopathology ; Prosencephalon/cytology/*physiology ; RNA, Messenger/genetics/metabolism ; RNA-Induced Silencing Complex/metabolism ; Up-Regulation
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2013-07-28
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Cacao ; Diet/*statistics & numerical data ; Humans ; Male ; *Nobel Prize
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Liithi, T. ; Haltiwanger, R. S. ; Greengard, P. ; Bähler, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1991
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: The neuron-specific synaptic vesicle-associated phosphoproteins synapsin I and synapsin II were shown to contain terminal 7V-acetylglucosamine (GlcNAc) residues as determined by specific labeling with bovine galactosyltrans-ferase and UDP-[3H]galactose. The β-elimination of galac-tosyltransferase radiolabeled synapsin I and subsequent analysis of released saccharide on high-voltage paper electrophoresis confirmed the presence of monosaccharidic GlcNAc moieties in O-linkage to the protein. Partial cleavage of synapsin I by collagenase, 2-nitro-5-thiocyanobenzoic acid, and Staphylococcus aureus V8 protease suggests that at least three glycosylation sites exist along the molecule. Taken together these data present the first evidence that a neuron-specific protein contains 0-glycosidically bound GlcNAc.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1991.tb02043.x

    Articles: DFG German National Licenses
  5. 5
    Whittaker, V. P ; Greengard, P

    Oxford, UK : Blackwell Publishing Ltd
    Published 1971
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract— The brain of a typical teleost fish, sea bass (Centrioprisles striatus), yielded subcellular fractions similar to those previously isolated from mammalian brain upon homogenization and differential and density gradient centrifuging. In particular, a well-defined synaptosomal fraction accounting for most of the bound acetylcholine of the tissue was obtained, although possibly because of the large amount of myelin in fish brain this and other fractions were not as homogeneous as the corresponding ones from guinea pig cerebral cortex. No difficulty was experienced in adapting the methods to the relatively small amounts of tissue (about 200 mg) obtainable from each fish. The isolation of synaptosomes in good yield indicates that teleost central presynaptic terminals have essentially the same physical properties as those of higher forms, permitting detachment and sealing under conditions of moderate liquid shear.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1971.tb00554.x

    Articles: DFG German National Licenses
  6. 6
    Clement-Cormier, Yvonne C. ; Parrish, R. G. ; Petzold, G. L. ; Kebabian, J. W. ; Greengard, P.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1975
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract— An adenylate cyclase present in the caudate nucleus of rat brain, which is selectively stimulated by low concentrations of dopamine, and which is believed to mediate dopaminergic synaptic transmission, has been characterized with respect to several properties. The parameters studied included temperature, pH, ATP concentration, Mg/ATP ratio, and metal ion specificity. The effects of other compounds, including EGTA, NaF and several guanosine nucleotides, were also tested on the dopa-mine-sensitive adenylate cyclase. In addition, the subcellular distribution of the enzyme was studied. The highest specific activity was found in subcellular fractions enriched in nerve endings. A half-maximal increase in the activity of the enzyme in a subcellular fraction occurred in the presence of 4 × 10−6 M dopamine. Fluphenazine, a dopamine antagonist, competitively inhibited the activity of the enzyme in this fraction, with a calculated inhibition constant (Ki) of 8 × 10−9M.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1471-4159.1975.tb12241.x

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0003-9861
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-9861(87)90404-8

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    0003-9861
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-9861(74)90066-6

    Articles: DFG German National Licenses
  9. 9
    Forn, J. ; Greengard, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-9861
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-9861(76)90216-2

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/bbrc.1993.2490

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/bbrc.1993.2527

    Articles: DFG German National Licenses
  12. 12
    GREENGARD, P.

    [s.l.] : Nature Publishing Group
    Published 1956
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] WORK now in progress on the metabolism of the peripheral nervous system requires more sensitive methods than are generally available for the assay of various intermediary metabolites. In recent years increasingly widespread use has been made of the difference of ultra-violet absorption properties ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/178632a0

    Articles: DFG German National Licenses
  13. 13
    Greengard, P. ; Robison, G.A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0891-5849
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0891-5849(93)90097-E

    Articles: DFG German National Licenses
  14. 14
    Kuo, J.F. ; Krueger, B.K. ; Sanes, J.R. ; Greengard, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0005-2744
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0005-2744(70)90180-4

    Articles: DFG German National Licenses
  15. 15
    Kuo, J.F. ; Greengard, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0005-2744
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0005-2744(70)90249-4

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    0003-2697
    Keywords:
    neurochemistry ; nitrocellulose ; protein blotting ; protein kinases ; protein phosphorylation ; synapsin I
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-2697(86)90600-7

    Articles: DFG German National Licenses
  17. 17
    Girault, J.-A. ; Gorelick, F.S. ; Greengard, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-2697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-2697(89)90741-0

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Nerve terminal ; Protein phosphorylation ; Synaptic vesicle
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(93)80242-M

    Articles: DFG German National Licenses
  19. 19
    Greengard, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-3956
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-3956(74)90077-6

    Articles: DFG German National Licenses
  20. 20
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Ca^2^+ ; Calmodulin ; Protein phosphorylation
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(83)80846-1

    Articles: DFG German National Licenses