Search Results - (Author, Cooperation:P. Ferrier)

Showing 1 - 5 results of 5, query time: 0.12s Refine Results
  1. 1
    Staff View
    Publication Date:
    2016-01-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cell Differentiation/*genetics ; Cell Lineage/*genetics ; Cell Proliferation ; Cells, Cultured ; Down-Regulation ; Embryonic Stem Cells/*cytology ; Enhancer Elements, Genetic/*physiology ; *Gene Expression Regulation ; Gene Regulatory Networks ; Macrophages/*cytology ; MafB Transcription Factor/metabolism ; Mice ; Proto-Oncogene Proteins c-maf/metabolism ; Single-Cell Analysis ; Transcriptional Activation
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    1600-065X
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1600-065X.1985.tb01126.x

    Articles: DFG German National Licenses
  3. 3
    Ferrier, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0145-2134
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Psychology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0145-2134(85)90022-5

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    1432-1211
    Keywords:
    Key words Thymus ; T lymphocytes ; Gene regulation ; Chemokines ; Thymic stroma
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract  A set of 3000 mouse thymus cDNAs was analyzed by extensive measurement of expression using complex-probe hybridization of DNA arrays ("quantitative differential screening"). The complex probes were initially prepared using total thymus RNA isolated from C57BL/6 wild-type (WT), CD3e- and RAG1-deficient mice. Over 100 clones displaying over- or under-expression by at least a factor of two between WT and knockout (KO) thymuses were further analyzed by measuring hybridization signatures with probes from a wide range of KO thymuses, cell types, organs, and embryonic thymuses. A restricted set of clones was selected by virtue of their expression spectra (modulation in KO thymuses and thymocytes, lymphoid cell specificity, and differential expression during embryonic thymus development), sequenced at one extremity, and compared to sequences in databases. Clones corresponding to previously identified genes (e.g., Tcrβ, Tcf1 or CD25) showed expression patterns that were consistent with existing data. Ten distinct clones corresponding to new genes were subjected to further study: Northern blot hybridization, in situ hybridization on thymus sections, and partial or complete mRNA sequence determination. Among these genes, we report a new serine peptidase highly expressed in cortical epithelial cells that we have named thymus-specific serine peptidase (TSSP), and an acidic protein expressed in thymocytes and of unknown function that we have named thymus-expressed acidic protein (TEAP). This approach identifies new molecules likely to be involved in thymocyte differentiation and function.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s002510050601

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1420-911X
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Description / Table of Contents:
    Zusammenfassung In einer prospektiven Untersuchung wurde bei 630 Frauen zwischen der 14. und der 20. Schwangerschaftswoche die Serum GGT dosiert, um einen Zusammenhang zwischen den Werten eines biologischen Markers der Alkoholisation und dem klinischen Status des Neugeborenen zu prüfen. In 7 % der Fälle wurde ein anormaler Wert beobachtet, wohingegen die Anamnäse nur in 1 % der Fälle einen Alkoholkonsun bestätigte. Die vorläufigen statistischen Analysen, die sich auf die Prüfung von 308 Neugeboren im Doppelblindversuch beziehen, zeigen eine Korrelation zwischen dem mütterlichen GGT-Werten und dem Geburtsgewicht, sowie den pre- und perinatalen Komplikationen. Jedoch ist die Empfindlichkeit dieses Tests schwach.
    Notes:
    Summary In order to investigate prospectively in pregnant women a correlation between serum levels of a biological marker of alcohol and the clinical status of the newborn, we measured the gamma-glutamyltransferase (GGT) in 630 women between 14 and 20 weeks of pregnancy. In 7 % of the cases, an elevated value was observed while history confirmed alcohol consumption in only 1 %. Preliminary statistical analysis established upon the blind examination of 308 newborns show a correlation between maternal GGT levels and birthweight as well as the pre-and perinatal complications. However, the sensitivity of this test is weak.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF02075881

    Articles: DFG German National Licenses