Search Results - (Author, Cooperation:P. Dubreuil)

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  1. 1
    Staff View
    Publication Date:
    2016-01-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cell Differentiation/*genetics ; Cell Lineage/*genetics ; Cell Proliferation ; Cells, Cultured ; Down-Regulation ; Embryonic Stem Cells/*cytology ; Enhancer Elements, Genetic/*physiology ; *Gene Expression Regulation ; Gene Regulatory Networks ; Macrophages/*cytology ; MafB Transcription Factor/metabolism ; Mice ; Proto-Oncogene Proteins c-maf/metabolism ; Single-Cell Analysis ; Transcriptional Activation
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    LEMONNIER, F. A. ; BIRNBAUM, D. Z. ; DUBREUIL, P. C. ; CAILLOL, D. H.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1982
    Staff View
    ISSN:
    1365-3083
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    The rates of dissociation from the surface of la-positive spleen cells of three different anti-Ia monoclonal antibodies were evaluated and compared with their inhibitory effects on T- lymphocyte proliferate responses involving the same spleen cell population, either as a source of accessory cells (responses to soluble antigens) or as allogeneic stimulating cells. In general, a direct relationship was observed between the affinity with which these monoclonal antibodies interact with Ia-positive cells and the magnitude of their inhibitory effects, whether soluble antigen- or alloantigen-induced responses were tested. These results indicate that the affinity of monoclonal antibodies is a factor that has to be considered to the same extent as their fine specificity when interpreting the results of inhibitory studies of T-cell responses by anti-Ia monoclonal antibodies.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-3083.1982.tb00718.x

    Articles: DFG German National Licenses
  3. 3
    Dubreuil, P. C. ; Caillol, Danielle H. ; Lemonnier, F. A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1982
    Staff View
    ISSN:
    1744-313X
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    We investigated the capacity of anti-I-Ak and anti-I-E/Ck monoclonal antibodies (m.Ab.) to inhibit T lymphocyte proliferative responses to soluble antigen (Keyhole limpet hemocyanin), alloantigens (H-2 or non-H-2 related) and a mitogen (Concanavalin A). Surprisingly, specific inhibition was observed in all circumstances, and with both anti-I-Ak and anti-I-E/Ck m.Ab., whether the responses tested were I restricted in cell mixing experiments or not.The significance of the inhibition by anti-Ia m.Ab. of non-Ia-restricted responses is still not completely understood. These results, however, strongly suggest that in vitro inhibition by anti-Ia antibodies of T cell proliferative responses does not necessarily indicate I restriction of the presentation to T lymphocytes of the corresponding antigen.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1744-313X.1982.tb00778.x

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    0040-4039
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0040-4039(01)91780-0

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(91)90066-S

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(87)90026-9

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(90)90006-L

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(91)90022-C

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(87)90017-8

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(90)90058-8

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(91)90009-9

    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(89)90003-9

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    0739-7240
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0739-7240(88)90016-1

    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    0167-4838
    Keywords:
    Angiotensin converting enzyme ; Gastric mucosal cell ; Gastrin ; Gastrin antagonist
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-4838(90)90182-F

    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    0168-1591
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0168-1591(90)90058-L

    Articles: DFG German National Licenses
  16. 16
    Dubreuil, P. ; Morisset, J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-0115
    Keywords:
    gastrin and duodenum growth ; hyperplasia ; somatocrinin ; somatostatin antiserum
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-0115(86)90194-1

    Articles: DFG German National Licenses
  17. 17
    Dubreuil, P. ; Rebourg, C. ; Merlino, M. ; Charcosset, A.
    Springer
    Published 1999
    Staff View
    ISSN:
    1572-9818
    Keywords:
    allele frequency estimation ; DNA bulks ; maize populations ; RFLP diversity
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract Molecular characterization by means of RFLPs of large sets of populations is presently limited by experimental costs. In order to reduce costs, we have evaluated a method based on the RFLP analysis of balanced bulks of DNA from several individuals. The precision of this approach for estimating allele frequencies within each population was investigated using (i) DNA extracted from controlled bulks of leaf tissues of maize inbred lines, (ii) data obtained from individual analyses of 10 maize populations. Both approaches showed that allele frequencies can generally be estimated with a high precision (coefficients of determination up to 0.99 for some probe-enzyme combinations assayed), relative to the variation in allele frequencies observed among maize populations. Although further efforts are needed to define a set of probe-enzyme combinations that can be routinely image processed, these results, and preliminary results from a 65 maize populations project, suggest that this approach could provide highly informative data for large sets of populations, and at relatively low costs.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1007571101815

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] To develop an assay for the FLT3/FLK2 ligand (FL) and to identify producer cells, we transfected the pro-B cell line Ba/F3 (ref. 6) with a cDNA clone encoding mouse FLT3/FLK2. Stable transformants, called Baflt, were then used as target cells in a proliferation assay with conditioned medium from ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/368643a0

    Articles: DFG German National Licenses
  19. 19
    Dubreuil, P. ; Charcosset, A.
    Springer
    Published 1999
    Staff View
    ISSN:
    1432-2242
    Keywords:
    Key words RFLP ; Maize ; Lines ; Populations
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract  RFLP markers have proven to be a reliable and highly informative tool for characterizing genetic diversity in maize. Joint analysis of inbred lines and populations should provide valuable information with respect to (1) a better understanding of the genetic basis of present elite germplasm and (2) the identification of populations that may prove to be useful sources of genetic diversity for breeding programs. Sixty-two inbred lines of known heterotic groups and ten maize populations, some of them significant contributors to the genetic basis of the heterotic groups, were assayed at 28 RFLP loci. Joint data analyses first underlined that the populations displayed a large number of alleles that were absent in the set of inbred lines. Associations among inbreds and populations further proved consistent with pedigree data of the inbreds and provided new information on the genetical basis of heterotic groups. In particular, European flint inbreds were revealed to be as close to the Northeastern U.S. flint population studied as to the typical European populations. These results advocate the analysis of larger sets of populations by means of molecular markers in order to (1) gain insight into the history of maize germplasm and (2) set up appropriate strategies for the use of genetic resources in breeding programs.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s001220051259

    Articles: DFG German National Licenses
  20. 20
    Burstin, J. ; Vienne, D. ; Dubreuil, P. ; Damerval, C.
    Springer
    Published 1994
    Staff View
    ISSN:
    1432-2242
    Keywords:
    Zea mays L. ; Genetic distances ; Protein polymorphism ; Two-dimensional electrophoresis ; Restriction fragment length polymorphism
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract Twenty-one maize (Zea mays L.) inbred lines were analysed using isozyme electrophoresis, restriction fragment length polymorphism (RFLP), and two-dimensional electrophoresis of denatured proteins (2-D PAGE). Our goal was (1) to assess the genetic variability among these lines which are potential progenitors for the development of forage maize hybrids in Europe, and (2) to compare the relationship pattern revealed by the polymorphism at marker loci with the one derived from the amount of protein variability assessed by computer-assisted analysis of the 2-D electrophoregrams. Fourteen markers were obtained from isozyme polymorphism, 84 from the restriction fragment length polymorphism, and 70 from protein shifts revealed by 2-D PAGE. The Rogers' distance computed on the set of molecular markers was the most efficient to describe the pedigree relationships between lines. Quantitative protein data gave a picture of relationships between lines clearly different from the monogenic markers. When unrelated pairs of lines were considered, the Rogers' distance was weakly correlated to distances based on quantitative variations in the amount of protein which may be consistent with their polygenic control and the occurrence of gene interactions.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00224522

    Articles: DFG German National Licenses