Search Results - (Author, Cooperation:P. Chardon)

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  1. 1
    M. A. Groenen ; A. L. Archibald ; H. Uenishi ; C. K. Tuggle ; Y. Takeuchi ; M. F. Rothschild ; C. Rogel-Gaillard ; C. Park ; D. Milan ; H. J. Megens ; S. Li ; D. M. Larkin ; H. Kim ; L. A. Frantz ; M. Caccamo ; H. Ahn ; B. L. Aken ; A. Anselmo ; C. Anthon ; L. Auvil ; B. Badaoui ; C. W. Beattie ; C. Bendixen ; D. Berman ; F. Blecha ; J. Blomberg ; L. Bolund ; M. Bosse ; S. Botti ; Z. Bujie ; M. Bystrom ; B. Capitanu ; D. Carvalho-Silva ; P. Chardon ; C. Chen ; R. Cheng ; S. H. Choi ; W. Chow ; R. C. Clark ; C. Clee ; R. P. Crooijmans ; H. D. Dawson ; P. Dehais ; F. De Sapio ; B. Dibbits ; N. Drou ; Z. Q. Du ; K. Eversole ; J. Fadista ; S. Fairley ; T. Faraut ; G. J. Faulkner ; K. E. Fowler ; M. Fredholm ; E. Fritz ; J. G. Gilbert ; E. Giuffra ; J. Gorodkin ; D. K. Griffin ; J. L. Harrow ; A. Hayward ; K. Howe ; Z. L. Hu ; S. J. Humphray ; T. Hunt ; H. Hornshoj ; J. T. Jeon ; P. Jern ; M. Jones ; J. Jurka ; H. Kanamori ; R. Kapetanovic ; J. Kim ; J. H. Kim ; K. W. Kim ; T. H. Kim ; G. Larson ; K. Lee ; K. T. Lee ; R. Leggett ; H. A. Lewin ; Y. Li ; W. Liu ; J. E. Loveland ; Y. Lu ; J. K. Lunney ; J. Ma ; O. Madsen ; K. Mann ; L. Matthews ; S. McLaren ; T. Morozumi ; M. P. Murtaugh ; J. Narayan ; D. T. Nguyen ; P. Ni ; S. J. Oh ; S. Onteru ; F. Panitz ; E. W. Park ; H. S. Park ; G. Pascal ; Y. Paudel ; M. Perez-Enciso ; R. Ramirez-Gonzalez ; J. M. Reecy ; S. Rodriguez-Zas ; G. A. Rohrer ; L. Rund ; Y. Sang ; K. Schachtschneider ; J. G. Schraiber ; J. Schwartz ; L. Scobie ; C. Scott ; S. Searle ; B. Servin ; B. R. Southey ; G. Sperber ; P. Stadler ; J. V. Sweedler ; H. Tafer ; B. Thomsen ; R. Wali ; J. Wang ; S. White ; X. Xu ; M. Yerle ; G. Zhang ; J. Zhang ; S. Zhao ; J. Rogers ; C. Churcher ; L. B. Schook
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-11-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Demography ; Genome/*genetics ; Models, Animal ; Molecular Sequence Data ; *Phylogeny ; Population Dynamics ; Sus scrofa/*classification/*genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Chardon, P. ; Renard, Ch. ; Kirszenbaum, M. ; Gefotin, Cl ; Cohen, D. ; Vaiman, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1985
    Staff View
    ISSN:
    1744-313X
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    Five HLA probes, one corresponding to class I genes, two corresponding to distinct class II light chain genes, DRβ and DQβ, and two to class II heavy chain genes, DRα and DQα, were used to analyse the genomic DNA of the pig. Three informative SLA typed families and four SLA recombinants were studied by Southern blot analysis. About 16 restriction fragments, generated by EcoR 1 or Hind III endonucleases, were revealed for each individual, either with the class I probe or the DRβ probe. The number of restriction fragments which hybridized with the other probes was generally lower. Several restriction fragment-length polymorphisms were found and these segregated with SLA DRβ- and DQα-like genes are probably tightly clustered within the SLA-D-MLR region.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1744-313X.1985.tb00841.x

    Articles: DFG German National Licenses
  3. 3
    Dezeure, F. ; Vaiman, M. ; Chardon, P.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-4781
    Keywords:
    (Swine) ; Heat shock protein ; Hsp70 gene ; MHC
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-4781(93)90087-T

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0888-7543(05)80226-5

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    0888-7543
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0888-7543(05)80226-5

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    1432-1211
    Keywords:
    Key words MHC ; Pig ; SLA ; Class II region ; Physical map
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s002510050611

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1432-1777
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s003359900618

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    1432-1777
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract. A swine DNA genomic library was constructed in yeast artificial chromosome (YAC) using the pYAC4 vector and the AB1380 strain. The DNA prepared from two Large White males was partially digested with EcoRI and size selected after both digestion and ligation. The YAC library contained 33792 arrayed clones with an average size of 280 kb as estimated by analysis of 2% of the clones, thus representing a threefold coverage of the swine haploid genome. The library was organized in pools to facilitate the PCR screening. The complexity of the library was tested both for unique and centromeric repeated sequences. In all, 20 out of 22 primer sets allowed the characterization of one to six clones containing specific unique sequences. These sequences are known to be on Chromosomes (Chrs) 1, 2, 5, 6, 7, 8, 13, 14, 15, 17, and X. Eight additional clones carrying centromeric repeat units were also isolated with a single primer set. The sequencing of 37 distinct repeat units of about 340 bp subcloned from these eight YACs revealed high sequence diversity indicating the existence of numerous centromeric repeat unit subfamilies in swine. Furthermore, the analysis of the restriction patterns with selected enzymes suggested a higher order organization of the repeat units. According to preliminary FISH experiments on a small number of randomly chosen YACs and YACs carrying specific sequences, the chimerism appeared to be low. In addition, primed in situ labeling experiments favored the idea that the YACs with centromeric repeat sequences were derived from a subset of metacentric and submetacentric chromosomes.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s003359900387

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    1432-1777
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract. A detailed physical map of the porcine MHC class III region on Chr 7 was constructed with a panel of probes in a series of hybridizations on genomic pulsed field gel electrophoresis (PFGE) Southern blots. A precise organization of the 700-kb segment of DNA between G18 and BAT1 can now be proposed, with more than 30 genes mapped to it. Comparison of this region with homologous regions in human and mouse showed only minor differences. The biggest difference was observed in the CYP21/C4 locus with only one CYP21 gene and one C4 gene found, whereas in human and mouse these genes are duplicated. These results show the class III region is very well conserved between pig, human, and mouse, in contrast with the class I and class II regions, which seem more prone to rearrangements.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s003359900105

    Articles: DFG German National Licenses
  10. 10
    Nunes, M. ; Peelman, L. ; Vaiman, M. ; Bourgeaux, N. ; Chardon, P.
    Springer
    Published 1994
    Staff View
    ISSN:
    1432-1777
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract A search for new potential coding sequences was conducted within two overlapping cosmid genomic DNA clusters of about 170 and 45 kb from the swine major histocompatibility complex class III region. The sequences were detected with various probes, including pools of swine cDNA, homologous and heterologous genomic sequences, and synthetic oligonucleotides. The 170 kb cluster was centered on the tumor necrosis factor genes (TNF), and the 45 kb cluster contained the heat-shock protein 70 genes (HSP70). The TNF cluster revealed the presence of five new genes: lymphotoxin β, BAT1, BAT2, BAT3, and a sequence related to DNA-binding factors. No sequence homologous to B144 was found in the TNF cluster, although other unidentified coding sequences may be present in this cluster. The HSP70 cluster contained a gene identified as BAT6, that is, tRNA-valyl synthetase. These results provide new evidence that the genomic maps of these various genes in the TNF and HSP70 sub-regions are similar in swine and human.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00411456

    Articles: DFG German National Licenses