Search Results - (Author, Cooperation:O. Nishimura)

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  1. 1
    Y. Umesono ; J. Tasaki ; Y. Nishimura ; M. Hrouda ; E. Kawaguchi ; S. Yazawa ; O. Nishimura ; K. Hosoda ; T. Inoue ; K. Agata
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-07-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Body Patterning/drug effects/*physiology ; Cell Differentiation ; Down-Regulation ; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors/metabolism ; Feedback, Physiological ; Head/physiology ; Logic ; MAP Kinase Signaling System/drug effects ; Phenotype ; Planarians/*anatomy & histology/drug effects/*physiology ; Receptors, Fibroblast Growth Factor/chemistry/metabolism ; Regeneration/drug effects/*physiology ; Stem Cells/cytology/metabolism ; Wnt Proteins/metabolism ; Wnt Signaling Pathway ; beta Catenin/deficiency/genetics/metabolism
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    0003-9861
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-9861(87)90558-3

    Articles: DFG German National Licenses
  3. 3
    Honda, S. ; Asano, T. ; Kajio, T. ; Nishimura, O.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0003-9861
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0003-9861(89)90147-1

    Articles: DFG German National Licenses
  4. 4
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/bbrc.1994.1653

    Articles: DFG German National Licenses
  5. 5
    Phillips, L.R. ; Nishimura, O. ; Fraser, B.A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0008-6215
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0008-6215(83)84021-X

    Articles: DFG German National Licenses
  6. 6
    Phillips, L.R. ; Nishimura, O. ; Fraser, B.A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0008-6215
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0008-6215(84)85224-6

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Lysylendopeptidase ; Nucleotide sequence ; Protein kinase C ; complementary DNA
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(86)80724-4

    Articles: DFG German National Licenses
  8. 8
    Harada, K. ; Nishimura, O. ; Mihara, S.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0021-9673
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0021-9673(01)94350-X

    Articles: DFG German National Licenses
  9. 9
    Staff View
    ISSN:
    0014-5793
    Keywords:
    (Vibrio cholerae non-01) ; Enterotoxin ; Heat-stability ; Primary structure
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(85)80163-0

    Articles: DFG German National Licenses
  10. 10
    Shibamoto, T. ; Nishimura, O.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0031-9422
    Keywords:
    Gramineae ; Vetiveria zizamioides ; phenols. ; vetiver oil
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0031-9422(82)83194-4

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0006-291X(74)90345-3

    Articles: DFG German National Licenses
  12. 12
    Yamada, T. ; Kato, K. ; Kawahara, K. ; Nishimura, O.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0006-291X(86)91004-1

    Articles: DFG German National Licenses
  13. 13
    Nishimura, O. ; Yabe, K. ; Saito, K. ; Yamashina, T. ; Iwaki, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0257-8972
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0257-8972(94)90039-6

    Articles: DFG German National Licenses
  14. 14
    Yabe, K. ; Nishimura, O. ; Fujihana, T. ; Iwaki, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0257-8972
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0257-8972(94)90006-X

    Articles: DFG German National Licenses
  15. 15
    Iwaki, M. ; Yabe, K. ; Suzuki, M. ; Nishimura, O.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0168-583X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0168-583X(87)80031-9

    Articles: DFG German National Licenses
  16. 16
    Saito, K. ; Yabe, K. ; Nishimura, O.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0168-583X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0168-583X(89)90862-8

    Articles: DFG German National Licenses
  17. 17
    Koyama, N. ; Kuriyama, M. ; Amano, N. ; Nishimura, O.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0168-1656
    Keywords:
    Cyanylation reaction ; DMAP-CN ; E. coli ; Insulinotropin ; NTCB ; Recombinant peptide
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0168-1656(94)90213-5

    Articles: DFG German National Licenses
  18. 18
    Nishimura, O. ; Yabe, K. ; Iwaki, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0368-2048
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0368-2048(89)85021-2

    Articles: DFG German National Licenses
  19. 19
    Sakaguchi, M. ; Honda, S. ; Ozawa, M. ; Nishimura, O.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Antiviral activity ; Higher structure ; IFN-γ
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(88)80671-9

    Articles: DFG German National Licenses
  20. 20
    Sawada, H. ; Iwasa, S. ; Nishimura, O. ; Kitano, K.
    Springer
    Published 1995
    Staff View
    ISSN:
    1432-0614
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Abstract  For industrial production of human monoclonal antibodies (hmAb) against hepatitis B virus surface antigen (HBsAg), we scaled-up a short-term perfusion culture in serum-free medium, which was chosen as the most suitable culture method, to a 50-l fermentor equipped with a rotating shear filter. Using hydrophobic chromatography as the initial step of hmAb purification, the mAb HBW4, HBW6 and W471 were isolated in good quality from the respective culture broths in yields of approximately 75%. Each of the three purified hmAb alone, and a cocktail of the three, protected chimpanzees against HB virus, when injected intravenously 3 h after viral challenge, as long as the serum antibody levels were significant. A pharmacokinetic study using cynomolgus monkeys demonstrated that the hmAb have a long plasma half-life and bioavailability of approximately 76% upon intramuscular injection in primates. Thus, anti-HBsAg hmAb produced by an industrial process are expected to be successfully used in clinical fields.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s002530050432

    Articles: DFG German National Licenses