Search Results - (Author, Cooperation:O. Nilsson)
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1Hien Vuong, Barada P. Dash, Sten O. Nilsson Lill, Douglas A. Klumpp
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-03-27Publisher: American Chemical Society (ACS)Print ISSN: 1523-7060Electronic ISSN: 1523-7052Topics: Chemistry and PharmacologyPublished by: -
2Andrew S. Tatton, Helen Blade, Steven P. Brown, Paul Hodgkinson, Leslie P. Hughes, Sten O. Nilsson Lill, Jonathan R. Yates
American Chemical Society (ACS)
Published 2018Staff ViewPublication Date: 2018-04-28Publisher: American Chemical Society (ACS)Print ISSN: 1528-7483Electronic ISSN: 1528-7505Topics: Chemistry and PharmacologyGeosciencesPhysicsPublished by: -
3B. Nystedt ; N. R. Street ; A. Wetterbom ; A. Zuccolo ; Y. C. Lin ; D. G. Scofield ; F. Vezzi ; N. Delhomme ; S. Giacomello ; A. Alexeyenko ; R. Vicedomini ; K. Sahlin ; E. Sherwood ; M. Elfstrand ; L. Gramzow ; K. Holmberg ; J. Hallman ; O. Keech ; L. Klasson ; M. Koriabine ; M. Kucukoglu ; M. Kaller ; J. Luthman ; F. Lysholm ; T. Niittyla ; A. Olson ; N. Rilakovic ; C. Ritland ; J. A. Rossello ; J. Sena ; T. Svensson ; C. Talavera-Lopez ; G. Theissen ; H. Tuominen ; K. Vanneste ; Z. Q. Wu ; B. Zhang ; P. Zerbe ; L. Arvestad ; R. Bhalerao ; J. Bohlmann ; J. Bousquet ; R. Garcia Gil ; T. R. Hvidsten ; P. de Jong ; J. MacKay ; M. Morgante ; K. Ritland ; B. Sundberg ; S. L. Thompson ; Y. Van de Peer ; B. Andersson ; O. Nilsson ; P. K. Ingvarsson ; J. Lundeberg ; S. Jansson
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-05-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Conserved Sequence/genetics ; DNA Transposable Elements/genetics ; *Evolution, Molecular ; Gene Silencing ; Genes, Plant/genetics ; Genome, Plant/*genetics ; Genomics ; Internet ; Introns/genetics ; Phenotype ; Picea/*genetics ; RNA, Untranslated/genetics ; Sequence Analysis, DNA ; Terminal Repeat Sequences/genetics ; Transcription, Genetic/geneticsPublished by: -
4Simon R. O. Nilsson; Christopher J. Heath; Samir Takillah; Steve Didienne; Kim Fejgin; Vibeke Nielsen; Jacob Nielsen; Lisa M. Saksida; Jean Mariani; Philippe Faure; Michael Didriksen; Trevor W. Robbins; Timothy J. Bussey; Adam C. Mar
Nature Publishing Group (NPG)
Published 2018Staff ViewPublication Date: 2018-11-15Publisher: Nature Publishing Group (NPG)Electronic ISSN: 2158-3188Topics: MedicinePublished by: -
5Staff View
Publication Date: 2013-11-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Arabidopsis/*growth & development ; Arabidopsis Proteins/*metabolism ; Flowers/*growth & development ; MADS Domain Proteins/*metabolism ; Repressor Proteins/*metabolism ; Transcription Factors/*metabolismPublished by: -
6Nilsson, O. ; Sandberg, O. ; Bäckström, G.
[S.l.] : American Institute of Physics (AIP)
Published 1986Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The paper describes a new hot-wire method for simultaneous determination of thermal conductivity and heat capacity per unit volume of electrically insulating liquids and solids under pressure. The method uses dc heating of the hot wire, whereas the temperature increase is recorded by an ac bridge circuit. The temperature data obtained are analyzed using the exact solution instead of the commonly used long time approximation. The procedure was tested on a number of alcohols and water and the accuracy was found to be 1.5%. New data on glycerol up to 1.5 GPa are presented. The appearance of an automagnetoresistance effect when Ni is employed as hot-wire probe is discussed.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The mixed leukocyte reaction (MLR) is impaired in multiple sclerosis and certain arthritides, notably rheumatoid arthritis. The present study shows that this phenomenon is not disease-Specific: cells from patients with multiple sclerosis react poorly also with cells from patients with arthritis. A time study of the reaction excludes the possibility of an initial Strong MLR followed by cell death – a phenomenon sometimes seen in animal experiments. A study of the affect ot patient sera on a two-way MLR between normal individuals shows that a small depressive effect is present with the patient sera, but this is not of the magnitude that it can explain the MLR impairment under study.Type of Medium: Electronic ResourceURL: -
8Leanza, G. ; Muir, J. ; Nilsson, O. G. ; Wiley, R. G. ; Dunnett, S. B. ; Björklund, A.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Selective depletion of nerve growth factor receptor-bearing neurons in the basal forebrain cholinergic nuclei by the immunotoxin 192 IgG-saporin offers a new and highly useful tool for the study of the role of the forebrain cholinergic system in cognitive functions. In the present study, we have tested the effects of 192 IgG—saporin in an operant delayed matching-to-position task which has previously been used to discriminate between delay-dependent learning impairments and delay-independent disturbances of non-mnemonic processes. Rats were first trained to criterion performance and then received intraventricular injections of 5 μg of 192 IgG—saporin 4 weeks prior to a second testing session. Rats with 192 IgG—saporin lesions displayed a significant delay-dependent decline in performance compared to normal controls, indicating a deficit in short-term memory. Administration of the muscarinic blocker scopolamine (0.5 mg/kg, i.p.) produced more pronounced impairment in the performance of the normal control rats across all delays, and induced further impairment also in animals with 192 IgG-saporin lesions. These effects were not observed following control injections of methyl scopolamine, suggesting that the impairment induced by scopolamine was due to the blockade of central muscarinic receptors. No improvement in performance was observed in either group following systemic treatment with the muscarinic cholinergic agonist arecoline (1.0 mg/kg). Biochemical and morphological analyses confirmed the selective and severe (〉90–95%) depletion of cholinergic neurons throughout the septal-diagonal band area and the nucleus basalis region by the intraventricular 192 IgG—saporin treatment. Although the immunotoxin was observed to produce additional damage to the cerebellar Purkinje cells, no gross motor abnormalities were observed that could contribute to the effects on accuracy in the task used here. In conclusion, the results show that selective combined lesions of the basal forebrain cholinergic neurons in the septal—diagonal band area and nucleus basalis produce long-lasting impairments in short-term memory, thus providing further support for a role of this system in cognitive functions.Type of Medium: Electronic ResourceURL: -
9Leanza, G. ; Nilsson, O. G. ; Wiley, R. G. ; Björklund, A.
Oxford, UK : Blackwell Publishing Ltd
Published 1995Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The elucidation of the functional role of the basal forebrain cholinergic system will require access to a highly specific and efficient cholinergic neurotoxin. Recently, selective depletion of the nerve growth factor (NGF) receptor-bearing cholinergic neurons in the rat basal forebrain and a dramatic loss of cholinergic innervation in the related cortical regions have been obtained following intraventricular injection of a newly introduced immunotoxin, 192 IgG-saporin. Here we extend these initial findings and report that administration of increasing doses (1.25, 2.5, 5.0 or 10 μg) of the 192 IgG-saporin conjugate into the lateral ventricles of adult rats induced dose-dependent impairments in the water maze task and passive avoidance retention, but only weak and inconsistent effects on locomotor activity. These behavioural changes were paralleled by a reduction in choline acetyltransferase activity in hippocampus and several cortical areas (up to 97%) and selective depletions of NGF receptor-positive cholinergic neurons in the septal-diagonal band area and nucleus basalis magnocellularis (up to 99%). By contrast, the non-cholinergic parvalbumin-containing neurons in the septum were completely spared, and other cholinergic projection systems (such as in the striatum, thalamus, brainstem and spinal cord) were unaffected even at the highest dose. The observed changes in the water maze and passive avoidance tasks, as well as the cholinergic cell loss, were maintained up to at least 8 months following the intraventricular injection of a single dose (5 μg) of the immunotoxin. The results confirm the usefulness of the 192 IgG-saporin toxin for selective and profound lesions of the basal forebrain cholinergic neurons and provide further support for a role of the basal forebrain cholinergic system in cognitive functions.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0005-2760Keywords: (Spleen, Liver) ; Ganglioside GM3 ; Gaucher's disease ; Glucosylceramide ; Glucosylsphingosine ; Lactosylceramide ; MSSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0005-2760Keywords: Ganglioside antigen ; Monoclonal antibody ; Oncofetal antigen ; Tumor-associated antigenSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
12Fredman, P. ; Brezicka, T. ; Holmgren, J. ; Lindholm, L. ; Nilsson, O. ; Svennerholm, L.
Amsterdam : ElsevierStaff ViewISSN: 0005-2760Keywords: Ganglioside Fuc-G"M"1: Ganglioside antigen ; Monoclonal antibodySource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0005-2760Keywords: (Human brain) ; Anion-exchange resin ; Ganglioside separation ; TetrasialogangliosideSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
14Mansson, J.-E. ; Fredman, P. ; Nilsson, O. ; Lindholm, L. ; Holmgren, J. ; Svennerholm, L.
Amsterdam : ElsevierStaff ViewISSN: 0005-2760Keywords: (Human pancreatic adenocarcinoma) ; Ganglioside ; Monoclonal antibody ; Sialosylfucosyllactotetraosylceramide ; SialosylfucosylneolactoetetraosylceramideSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
15Oliva, B. ; Wastlund, M. ; Nilsson, O. ; Cardenas, R. ; Querol, E. ; Aviles, F.X. ; Tapia, O.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XKeywords: [abr] CPA; carboxypeptidase A ; [abr] MD; molecular dynamics ; [abr] NIS; non-inertial solvent ; [abr] PCI; potato carboxypeptidase A inhibitorSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0005-2736Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
17Oliva, B. ; Wastlund, M. ; Nilsson, O. ; Cardenas, R. ; Querol, E. ; Aviles, F.X. ; Tapia, O.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XKeywords: [abr] CPA; carboxypeptidase A ; [abr] MD; molecular dynamics ; [abr] NIS; non-inertial solvent ; [abr] PCI; potato carboxypeptidase A inhibitorSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
18Oliva, B. ; Nilsson, O. ; Wastlund, M. ; Cardenas, R. ; Querol, E. ; Avies, F.X. ; Tapia, O.
Amsterdam : ElsevierStaff ViewISSN: 0006-291XKeywords: [abr] CPA; carboxypeptidase A ; [abr] MD; molecular dynamics ; [abr] NIS; non-inertial solvent ; [abr] PCI; potato carboxypeptidase A inhibitor ; [abr] PCIm; Pro-36-Gly mutant form ; [abr] PCIw; the PCI wild type formSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] For freezing, small specimens are rapidly frozen in liquid nitrogen according to the usual technique for freeze-drying. The frozen specimens are collected in a small weighing bottle with grounded stopper. The bottle contains a substance suitable for vapour fixation and serves as a fixation chamber ...Type of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0013-4686Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: