Search Results - (Author, Cooperation:Neupert)

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  1. 1
    Predel, R. ; Neupert, S. ; Wicher, D. ; Gundel, M. ; Roth, S. ; Derst, C.

    Oxford, UK : Blackwell Science Ltd
    Published 2004
    Staff View
    ISSN:
    1460-9568
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    FMRFamides belong to the most extensively studied neuropeptides in invertebrates and exhibit diverse physiological effects on different target organs, such as muscles, intestine and the nervous system. This study on the American cockroach confirms for the first time that extended FMRFamides occur in non-dipteran insects. By means of tandem mass spectrometry, these neuropeptides were structurally elucidated, and sequence information was used for subsequent cloning of the cockroach FMRFamide gene. This precursor gene encodes for 24 putative peptides and shows sufficient similarity with the Drosophila FMRFamide gene. Of the 24 peptides, 23 were detected by mass spectrometric methods; it is the highest number of neuropeptide forms shown to be expressed from a single precursor in any insect. The expression was traced back to single neurons in the thoracic ganglia. The unique accumulation of these FMRFamide-related peptides in thoracic perisympathetic organs provides the definite evidence for a tagma-specific distribution of peptidergic neurohormones in neurohaemal release sites of the insect CNS. Excitatory effects of the cockroach FMRFamides were observed on antenna–heart preparations. In addition, the newly described FMRFamides reduce the spike frequency of dorsal-unpaired median neurons and reduce the intracellular calcium concentration, which may affect the peripheral release of the biogenic amine octopamine.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1460-9568.2004.03598.x

    Articles: DFG German National Licenses
  2. 2
    Staff View
    ISSN:
    0304-4157
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0304-4157(89)90002-6

    Articles: DFG German National Licenses
  3. 3
    Westermann, Benedikt ; Neupert, Walter

    [s.l.] : Nature Publishing Group
    Published 2003
    Staff View
    ISSN:
    1546-1696
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    [Auszug] What is the set of proteins that constitute an organelle in its entirety? Having the answer to this question is the dream of many cell biologists. The advent of the 'omics' era has changed the dream to an experimentally tractable problem. Several systematic approaches are being pursued ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/nbt0303-239

    Articles: DFG German National Licenses
  4. 4
    Kozany, Christian ; Mokranjac, Dejana ; Sichting, Martin ; Neupert, Walter ; Hell, Kai

    [s.l.] : Nature Publishing Group
    Published 2004
    Staff View
    ISSN:
    1545-9985
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Medicine
    Notes:
    [Auszug] Mitochondria import the vast majority of their proteins from the cytosol. The mitochondrial import motor of the TIM23 translocase drives the translocation of precursor proteins across the outer and inner membrane in an ATP-dependent reaction. Tim44 at the inner face of the translocation pore ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/nsmb734

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    0303-2647
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0303-2647(80)90025-8

    Articles: DFG German National Licenses
  6. 6
    Neupert, W. ; Brdiczka, D. ; Bucher, Th.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(67)80012-3

    Articles: DFG German National Licenses
  7. 7
    Neupert, W. ; Brdiczka, D. ; Bucher, Th.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0006-291X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0006-291X(67)80012-3

    Articles: DFG German National Licenses
  8. 8
    Stuart, Rosemary A. ; Neupert, Walter

    [s.l.] : Macmillan Magazines Ltd.
    Published 2000
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Cellular membranes are formed by the insertion of newly synthesized components, such as lipids and proteins, into pre-existing membranes. Each membrane is made up of a specific and unique set of proteins, which determines its identity. As a consequence, the insertion of proteins cannot be a ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/35020668

    Articles: DFG German National Licenses
  9. 9
    Leonhard, Klaus ; Stiegler, Alexandra ; Neupert, Walter ; Langer, Thomas

    [s.l.] : Macmillan Magazines Ltd.
    Published 1999
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] The AAA domain, a conserved Walker-type ATPase module, is a feature of members of the AAA family of proteins,, which are involved in many cellular processes, including vesicular transport, organelle biogenesis, microtubule rearrangement and protein degradation. The function of the AAA domain, ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/18704

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] The outer membranes of mitochondria and chloroplasts are distinguished by the presence of β-barrel membrane proteins. The outer membrane of Gram-negative bacteria also harbours β-barrel proteins. In mitochondria these proteins fulfil a variety of functions such as transport of small ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/nature02208

    Articles: DFG German National Licenses
  11. 11
    Sirrenberg, Christian ; Endres, Maxi ; Fölsch, Heike ; Stuart, Rosemary A. ; Brunner, Michael ; Neupert, Walter

    [s.l.] : Macmillan Magazines Ltd.
    Published 1998
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] Import of nuclear-encoded precursor proteins into mitochondria and their subsequent sorting into mitochondrial subcompartments is mediated by translocase enzymes in the mitochondrial outer and inner membranes. Precursor proteins carrying amino-terminal targeting signals are translocated into ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/36136

    Articles: DFG German National Licenses
  12. 12
    Tomboulian, D.H. ; Bedo, D.E. ; Neupert, W.M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-3697
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0022-3697(57)90032-X

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    0005-2728
    Keywords:
    Contact site ; Mitochondrion ; Protein import ; Protein unfolding
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0005-2728(90)90257-5

    Articles: DFG German National Licenses
  14. 14
    Schwarz, E. ; Neupert, W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0005-2728
    Keywords:
    Chaperone ; Cytochrome biogenesis ; Import receptor ; Mitochondrion ; Protein folding ; Protein import
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0005-2728(94)90125-2

    Articles: DFG German National Licenses
  15. 15
    Staff View
    ISSN:
    0378-1119
    Keywords:
    PCR cloning ; Saccharomyces cerevisiae genomic library ; heat-shock gene ; prenylation signal ; stress-induced gene expression
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0378-1119(94)90333-6

    Articles: DFG German National Licenses
  16. 16
    Staff View
    ISSN:
    0005-2787
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0005-2787(77)90149-6

    Articles: DFG German National Licenses
  17. 17
    Stuart, R.A. ; Lill, R. ; Neupert, W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0962-8924
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0962-8924(93)90176-2

    Articles: DFG German National Licenses
  18. 18
    Pfanner, N. ; Neupert, W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0955-0674
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0955-0674(89)90025-2

    Articles: DFG German National Licenses
  19. 19
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Import receptor ; Mitochondrial outer membrane ; Protein translocation
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(92)81345-M

    Articles: DFG German National Licenses
  20. 20
    Segui-Real, B. ; Stuart, R.A. ; Neupert, W.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-5793
    Keywords:
    Mitochondria ; Protein sorting ; Protein translocation ; Receptor
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0014-5793(92)81171-H

    Articles: DFG German National Licenses