Search Results - (Author, Cooperation:N. V. Grishin)
-
1Latest Papers from Table of Contents or Articles in PressV. S. Tagliabracci ; J. L. Engel ; J. Wen ; S. E. Wiley ; C. A. Worby ; L. N. Kinch ; J. Xiao ; N. V. Grishin ; J. E. Dixon
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-05-15Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Abnormalities, Multiple/genetics/metabolism ; Amino Acid Motifs ; Amino Acid Sequence ; Animals ; Calcification, Physiologic ; Casein Kinase I ; Casein Kinases/metabolism ; Caseins/*metabolism ; Cattle ; Cell Line, Tumor ; Cleft Palate/genetics/metabolism ; Exophthalmos/genetics/metabolism ; Extracellular Matrix Proteins/chemistry/genetics/*metabolism/secretion ; Glycoproteins/metabolism ; Golgi Apparatus/*enzymology ; HEK293 Cells ; HeLa Cells ; Humans ; Microcephaly/genetics/metabolism ; Milk/enzymology ; Molecular Sequence Data ; Mutation ; Osteopontin ; Osteosclerosis/genetics/metabolism ; Phosphorylation ; Protein Sorting Signals ; Recombinant Fusion Proteins/chemistry/metabolism/secretion ; *Secretory Pathway ; Substrate SpecificityPublished by: -
2Latest Papers from Table of Contents or Articles in PressJ. Y. Lee ; L. N. Kinch ; D. M. Borek ; J. Wang ; I. L. Urbatsch ; X. S. Xie ; N. V. Grishin ; J. C. Cohen ; Z. Otwinowski ; H. H. Hobbs ; D. M. Rosenbaum
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-05-05Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressS. Shoji-Kawata ; R. Sumpter ; M. Leveno ; G. R. Campbell ; Z. Zou ; L. Kinch ; A. D. Wilkins ; Q. Sun ; K. Pallauf ; D. MacDuff ; C. Huerta ; H. W. Virgin ; J. B. Helms ; R. Eerland ; S. A. Tooze ; R. Xavier ; D. J. Lenschow ; A. Yamamoto ; D. King ; O. Lichtarge ; N. V. Grishin ; S. A. Spector ; D. V. Kaloyanova ; B. Levine
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-02-01Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Amino Acid Sequence ; Animals ; Apoptosis Regulatory Proteins/*chemistry/metabolism/pharmacology/*therapeutic use ; Autophagy/*drug effects ; Cell Membrane Permeability ; Cells, Cultured ; Chikungunya virus/drug effects ; HIV-1/drug effects/metabolism/physiology ; HeLa Cells ; Humans ; Macrophages/cytology ; Membrane Proteins/*chemistry/metabolism/pharmacology/*therapeutic use ; Mice ; Molecular Sequence Data ; Peptide Fragments/*chemistry/metabolism/*pharmacology ; Recombinant Fusion Proteins/chemistry/metabolism/pharmacology ; Virus Replication/drug effects ; West Nile virus/drug effects ; nef Gene Products, Human Immunodeficiency Virus/metabolism ; tat Gene Products, Human Immunodeficiency Virus/genetics/metabolismPublished by: -
4Latest Papers from Table of Contents or Articles in PressS. Liu ; X. Cai ; J. Wu ; Q. Cong ; X. Chen ; T. Li ; F. Du ; J. Ren ; Y. T. Wu ; N. V. Grishin ; Z. J. Chen
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-02-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/chemistry/*metabolism ; Adaptor Proteins, Vesicular Transport/chemistry/*metabolism ; Amino Acid Sequence ; Animals ; Cell Line ; Humans ; I-kappa B Kinase/metabolism ; Interferon Regulatory Factor-3/chemistry/*metabolism ; Interferon-alpha/biosynthesis ; Interferon-beta/biosynthesis ; Membrane Proteins/chemistry/*metabolism ; Mice ; Molecular Sequence Data ; Phosphorylation ; Protein Binding ; Protein Multimerization ; Protein-Serine-Threonine Kinases/metabolism ; Recombinant Proteins/metabolism ; Sendai virus/physiology ; Serine/metabolism ; Signal Transduction ; Ubiquitination ; Vesiculovirus/physiologyPublished by: -
5Latest Papers from Table of Contents or Articles in PressKim, S. B., Zhang, L., Yoon, J., Lee, J., Min, J., Li, W., Grishin, N. V., Moon, Y.-A., Wright, W. E., Shay, J. W.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-08-16Publisher: The American Society for Microbiology (ASM)Print ISSN: 0270-7306Electronic ISSN: 1098-5549Topics: BiologyMedicinePublished by: -
6Articles: DFG German National LicensesOsterman, A. L. ; Grishin, N. V. ; Smulevitch, S. V. ; Matz, M. V. ; Zagnitko, O. P. ; Revina, L. P. ; Stepanov, V. M.
Springer
Published 1992Staff ViewISSN: 1573-4943Keywords: Primary structure ; carboxypeptidase T ; carboxypeptidase family ; alignmentSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyNotes: Abstract The primary structure of carobxypeptidase T—a Zn-dependent extracellular enzyme ofThermoactinomyces vulgaris—was determined from the clonedcpT gene nucleotide sequence and compared to Zn-carboxypeptidases from various organisms. The compilation and analysis of multiple alignment accompanied by consideration of available tertiary structure data have shown that in the overall spatial structure and active site arrangement CpT is similar to other enzymes constituting the Zn-carboxypeptidase family. Nine of 16 amino acid residues found to be strictly invariant are presumably located close to the active site. The preservation of His69, Glu72, Asn144, Arg145, His196, Tyr248, and Glu270 identified previously as essential catalytic site participants implicates basically the same catalytic mechanism in the Zn-carboxy-peptidase family. It is proposed that Pro205 and Asp256 should play an important role in proper S1′-pocket spatial arrangement. The comparative analysis of amino acid variations in S1′-pocket enabled us to reveal structural determinants of the Zn-carboxypeptidase primary specificity. The relatively reduced size of the pocket and negative charge of Asp253 are supposed to contribute correspondingly to A- and B-type substrate preferences of carboxypeptidase T endowed with dual primary specificity.Type of Medium: Electronic ResourceURL: