Search Results - (Author, Cooperation:N. Trede)

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  1. 1
    Staff View
    Publication Date:
    2013-04-13
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    DNA Mutational Analysis ; Genetic Loci ; *Haploinsufficiency ; Heterotaxy Syndrome/*genetics ; Humans ; Mutation ; Pedigree ; Penetrance ; Receptors, Laminin/*genetics ; Ribosomal Proteins/*genetics ; Spleen/*abnormalities/growth & development
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Trede, N. S. ; Urbanek, R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1398-9995
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Twenty patients with a proven sensitization to grass pollens were treated with parenteral “priming” and subsequently with either oral “booster” (n-10) or placebo (n=10) extension course. The study was carried out in a double-blind manner. Cumulative preseasonal parenteral dosage was 3,100 NU (Noon Units), patients in the oral group subsequently received 123.9 mg of grass pollen extract during the pollen season. No side effects were noted after intake of the oral preparation. No significant differences (95% confidence interval) were noted comparing results of in vivo (skin prick test and conjunctival provocation test) and in vivo tests (specific serum IgE- And IgG-antibodies) between the two groups. Analysis of symptom and medication scores as well as subjective assessment of patients revealed no superiority of oral “booster” over placebo. Data obtained in this study does not support the concept of combined parenteral and oral treatment. This is in contrast to work reported previously.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses