Search Results - (Author, Cooperation:N. Sanchez)

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  1. 1
    P. Bailey ; D. K. Chang ; K. Nones ; A. L. Johns ; A. M. Patch ; M. C. Gingras ; D. K. Miller ; A. N. Christ ; T. J. Bruxner ; M. C. Quinn ; C. Nourse ; L. C. Murtaugh ; I. Harliwong ; S. Idrisoglu ; S. Manning ; E. Nourbakhsh ; S. Wani ; L. Fink ; O. Holmes ; V. Chin ; M. J. Anderson ; S. Kazakoff ; C. Leonard ; F. Newell ; N. Waddell ; S. Wood ; Q. Xu ; P. J. Wilson ; N. Cloonan ; K. S. Kassahn ; D. Taylor ; K. Quek ; A. Robertson ; L. Pantano ; L. Mincarelli ; L. N. Sanchez ; L. Evers ; J. Wu ; M. Pinese ; M. J. Cowley ; M. D. Jones ; E. K. Colvin ; A. M. Nagrial ; E. S. Humphrey ; L. A. Chantrill ; A. Mawson ; J. Humphris ; A. Chou ; M. Pajic ; C. J. Scarlett ; A. V. Pinho ; M. Giry-Laterriere ; I. Rooman ; J. S. Samra ; J. G. Kench ; J. A. Lovell ; N. D. Merrett ; C. W. Toon ; K. Epari ; N. Q. Nguyen ; A. Barbour ; N. Zeps ; K. Moran-Jones ; N. B. Jamieson ; J. S. Graham ; F. Duthie ; K. Oien ; J. Hair ; R. Grutzmann ; A. Maitra ; C. A. Iacobuzio-Donahue ; C. L. Wolfgang ; R. A. Morgan ; R. T. Lawlor ; V. Corbo ; C. Bassi ; B. Rusev ; P. Capelli ; R. Salvia ; G. Tortora ; D. Mukhopadhyay ; G. M. Petersen ; D. M. Munzy ; W. E. Fisher ; S. A. Karim ; J. R. Eshleman ; R. H. Hruban ; C. Pilarsky ; J. P. Morton ; O. J. Sansom ; A. Scarpa ; E. A. Musgrove ; U. M. Bailey ; O. Hofmann ; R. L. Sutherland ; D. A. Wheeler ; A. J. Gill ; R. A. Gibbs ; J. V. Pearson ; A. V. Biankin ; S. M. Grimmond
    Nature Publishing Group (NPG)
    Published 2016
    Staff View
    Publication Date:
    2016-02-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Carcinoma, Pancreatic ; Ductal/classification/genetics/immunology/metabolism/pathology ; Cell Line, Tumor ; DNA Methylation ; DNA-Binding Proteins/genetics ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Genes, Neoplasm/*genetics ; Genome, Human/*genetics ; *Genomics ; Hepatocyte Nuclear Factor 3-beta/genetics ; Hepatocyte Nuclear Factor 3-gamma/genetics ; Histone Demethylases/genetics ; Homeodomain Proteins/genetics ; Humans ; Mice ; Mutation/*genetics ; Nuclear Proteins/genetics ; Pancreatic Neoplasms/*classification/*genetics/immunology/metabolism/pathology ; Prognosis ; Receptors, Cytoplasmic and Nuclear/genetics ; Survival Analysis ; Trans-Activators/genetics ; Transcription Factors/genetics ; Transcription, Genetic ; Transcriptome ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Proteins/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-03-06
    Publisher:
    Hindawi
    Print ISSN:
    1687-6105
    Electronic ISSN:
    1687-6113
    Topics:
    Medicine
    Published by:
    http://www.hindawi.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2014-08-15
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Autophagy ; Carcinoma, Pancreatic Ductal/drug therapy/genetics/*metabolism/*pathology ; Cell Respiration/drug effects ; Cell Survival/drug effects ; Disease Models, Animal ; Female ; Gene Expression Regulation, Neoplastic ; Genes, p53/genetics ; Glycolysis ; Lysosomes/metabolism ; Mice ; Mitochondria/drug effects/*metabolism ; Mutation/genetics ; Neoplasm Recurrence, Local/prevention & control ; Neoplastic Stem Cells/drug effects/metabolism/pathology ; Oxidative Phosphorylation/drug effects ; Pancreatic Neoplasms/drug therapy/genetics/*metabolism/*pathology ; Proto-Oncogene Proteins p21(ras)/*genetics/metabolism ; Recurrence ; Signal Transduction
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    M. Arumugam ; J. Raes ; E. Pelletier ; D. Le Paslier ; T. Yamada ; D. R. Mende ; G. R. Fernandes ; J. Tap ; T. Bruls ; J. M. Batto ; M. Bertalan ; N. Borruel ; F. Casellas ; L. Fernandez ; L. Gautier ; T. Hansen ; M. Hattori ; T. Hayashi ; M. Kleerebezem ; K. Kurokawa ; M. Leclerc ; F. Levenez ; C. Manichanh ; H. B. Nielsen ; T. Nielsen ; N. Pons ; J. Poulain ; J. Qin ; T. Sicheritz-Ponten ; S. Tims ; D. Torrents ; E. Ugarte ; E. G. Zoetendal ; J. Wang ; F. Guarner ; O. Pedersen ; W. M. de Vos ; S. Brunak ; J. Dore ; M. Antolin ; F. Artiguenave ; H. M. Blottiere ; M. Almeida ; C. Brechot ; C. Cara ; C. Chervaux ; A. Cultrone ; C. Delorme ; G. Denariaz ; R. Dervyn ; K. U. Foerstner ; C. Friss ; M. van de Guchte ; E. Guedon ; F. Haimet ; W. Huber ; J. van Hylckama-Vlieg ; A. Jamet ; C. Juste ; G. Kaci ; J. Knol ; O. Lakhdari ; S. Layec ; K. Le Roux ; E. Maguin ; A. Merieux ; R. Melo Minardi ; C. M'Rini ; J. Muller ; R. Oozeer ; J. Parkhill ; P. Renault ; M. Rescigno ; N. Sanchez ; S. Sunagawa ; A. Torrejon ; K. Turner ; G. Vandemeulebrouck ; E. Varela ; Y. Winogradsky ; G. Zeller ; J. Weissenbach ; S. D. Ehrlich ; P. Bork
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-04-22
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Bacteria/*classification/genetics ; Bacterial Typing Techniques ; Biodiversity ; Biomarkers/analysis ; Europe ; Feces/microbiology ; Female ; Humans ; Intestines/*microbiology ; Male ; *Metagenome ; Metagenomics ; Phylogeny
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    ISSN:
    1433-0423
    Keywords:
    Schlüsselwörter Chagas-Krankheit ; Parasitäre Infektion ; Romaña-Zeichen ; Retinales Pigmentepithel ; Key words Chagas' disease ; Parasitic infection ; Romaña's sign ; Retinal pigment epithelium
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Description / Table of Contents:
    Background: In Central and South America, Chagas' disease is of great epidemiologic importance. The epidemiologic agent is represented by Trypanosoma cruzi, a monocellular parasite, instrumental in human infection is the presence of vectors, which are various species of hematophagous bugs. The eye is one of the most important entrance sites of the parasite, and relatively little information about the relationship between Chagas' disease and eye complications is available. Patients and methods: We examined 79 chagasic patients in order to detect changes in the retina. As a control group, we examined 48 patients with negative serology within the same age range and from the same regions. For every patient we completed a routine ophthalmologic examination, with inspection of the retina using direct and indirect ophthalmoscopy. Results: In most of the chagasic patients, the ocular fundus was unobtrusive; in only 6 out of 79 cases (7.6%) we did observe small parafoveolar retinal pigment epithelium defects and in 1 case (1.3%) distinct pigment epithelium atrophy of the posterior pole. No comparable findings were observed in the control group. Conclusion: Compared with the examination results of the control group, in the patients with intermediate and chronic Chagas' disease we observed an accumulation of retinal pigment epithelium defects, which, however, did not cause a significant loss of vision.
    Notes:
    Fragestellung: Welche Netzhautveränderungen können bei der in Südamerika endemischen, durch Trypanosoma cruzi hervorgerufenen Chagas-Krankheit beobachtet werden? Patienten und Methode: In der vorliegenden Studie wurden 79 infizierte Patienten ophthalmologisch untersucht, um Informationen über mögliche Netzhautveränderungen zu bekommen. Bei jedem Patienten wurden die Netzhaut mit direkter und indirekter Ophthalmoskopie untersucht sowie, bei vorliegenden Augenhintergrundsveränderungen, eine fluoreszenzangiographische Untersuchung durchgeführt. Mit derselben Methode wurde eine Kontrollgruppe von 48 nichtinfizierten Patienten untersucht. Ergebnisse: Bei 6 der 79 Patienten (7,6%) fanden wir kleine parafoveolare Defekte des retinalen Pigmentepithels sowie in 1 Fall (1,3%) eine ausgeprägte Pigmentepithelatrophie des hinteren Augenpols. Die Kontrollgruppe lieferte keine vergleichbaren Befunde. Schlußfolgerung: Erstmals wurde in dieser Studie eine größere Gruppe von Chagas-Patienten ophthalmologisch untersucht. Die Ergebnisse zeigen, daß man auch intraokulare Veränderungen erwarten kann, die bei den hier untersuchten Patienten allerdings keine signifikanten Visuseinschränkungen verursachten.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s003470050103

    Articles: DFG German National Licenses
  6. 6
    Antrobus, S. ; Husain, D. ; Lei, Jie ; Castaño, F. ; Rayo, M. N. Sanchez

    New York, NY : Wiley-Blackwell
    Published 1995
    Staff View
    ISSN:
    0538-8066
    Keywords:
    Chemistry ; Physical Chemistry
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Chemistry and Pharmacology
    Notes:
    Time-resolved investigations of the atomic resonance fluorescence Sr(53P1 → 51S0) and the molecular chemiluminescence from SrCl(A2Π1/2,3/2, B2Σ+ → X2Σ+) are reported following the reaction of the electronically excited strontium atom, Sr(5s5p(3PJ)), 1.807 eV above its 5s2(1S0) electronic ground state, with CH2Cl2. The optically metastable strontium atom was generated by pulsed dye-laser excitation of ground state strontium vapor to the Sr(53P1) state at λ = 689.3 nm (Sr(53P1 ← 51S0)) at elevated temperature (850 K) in the presence of excess helium buffer gas in which rapid Boltzmann equilibration within the 53PJ manifold takes place. Sr(53PJ) was then monitored by time-resolved atomic fluorescence from Sr(53P1) at the resonance wavelength together with chemiluminescence from electronically excited SrCl resulting from reaction of the excited atom with CH2Cl2. The molecular systems recorded in the time-domain were SrCl(A2Π1/2 → X2Σ+) (Δν = 0, λ = 674 nm), SrCl(A2Π3/2 → X2Σ+) (Δν = 0, λ = 660 nm), and SrCl(B2Σ+ → X2Σ+) (Δν = 0, λ = 636 nm). Both the A2Π (179.0 kJ mol-1) and (B2Σ+(188.0) kJ mol-1) states of SrCl are energetically accessible on collision between Sr(3P) and CH2Cl2. Exponential decay profiles for both the atomic and molecular (A,B - X) chemiluminescence emission are observed and the first-order decay coefficients characterized in each case. These are found to be equal under identical conditions and hence SrCl(A2Π, B2Σ+) are shown to arise from direct Cl-atom abstractions on reaction with this halogenated species. The combination of integrated molecular and atomic intensity measurements, coupled with optical sensitivity calibration, yields estimations of the branching ratios into the A1/2,3/2, B, and X states arising from Sr(53 PJ) + CH2Cl2 which are found to be as follows: A1/2, 3.0 × 10-3; A3/2, 1.7 × 10-3; B, 4.4 × 10-4 yielding ΣSrCl(A1/2 + A3/2 + B) = 5.1 × 10-3. As only the X, A and B states of SrCl are accessible on reaction, this indicates an upper limit for the branching ratio into the ground state of 0.995. The present results are compared with previous time-resolved measurements on SrF, Cl, Br(A2Π,B2Σ+ - X2Σ+) that we have reported on various halogenated species and with analogous chemiluminescence studies on Sr(3P) with other halides obtained from molecular beam measurements. The results are further compared with those from a series of previous analogous investigations in the time-domain we have presented of molecular emissions from CaF, Cl, Br, I (A,B - X) arising from the collisions of Ca(43PJ) with appropriate halides and with branching ratio data for Ca(43PJ) obtained in beam measurements. © 1995 John Wiley & Sons, Inc.
    Additional Material:
    12 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1002/kin.550270802

    Articles: DFG German National Licenses
  7. 7
    Staff View
    Publication Date:
    2018-03-13
    Publisher:
    Wiley-Blackwell
    Print ISSN:
    0894-3230
    Electronic ISSN:
    1099-1395
    Topics:
    Chemistry and Pharmacology
    Physics
    Published by:
    http://www.wiley.com/wiley-blackwell

    Latest Papers from Table of Contents or Articles in Press
  8. 8
    Staff View
    Publication Date:
    2018-03-06
    Publisher:
    Rockefeller University Press
    Print ISSN:
    0022-1007
    Electronic ISSN:
    1540-9538
    Topics:
    Medicine
    Keywords:
    Neuroscience
    Published by:
    http://www.rupress.org/

    Latest Papers from Table of Contents or Articles in Press
  9. 9
    Staff View
    Publication Date:
    2018-06-16
    Publisher:
    The American Association for Cancer Research (AACR)
    Print ISSN:
    1078-0432
    Electronic ISSN:
    1557-3265
    Topics:
    Medicine
    Published by:
    http://www.aacr.org/

    Latest Papers from Table of Contents or Articles in Press
  10. 10
    de Vega, H. J. ; Sánchez, N. ; Combes, F.

    [s.l.] : Nature Publishing Group
    Published 1996
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] The interstellar medium (ISM) is an ensemble of gas clouds and dust, composed mainly of hydrogen (either atomic H i or molecular H2) and helium (~25% by mass), with other elements present in trace amounts (dust is only ~1% in mass). The bulk of the ISM is distributed in cold clouds (temperature, T ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/383056a0

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0378-1119
    Keywords:
    Gram-negative bacteria ; Recombinant DNA ; auxins ; iaaMH operon ; indoleacetic acid production ; plasmid replication ; shuttle vectors
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0378-1119(90)90507-N

    Articles: DFG German National Licenses
  12. 12
    Sanchez, N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9601
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0375-9601(85)90673-5

    Articles: DFG German National Licenses
  13. 13
    Sanchez, N. ; Signore, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0920-5632
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0920-5632(90)90631-4

    Articles: DFG German National Licenses
  14. 14
    Nugent, J.B. ; Sanchez, N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0014-4983
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    History
    Economics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0014-4983(89)90022-3

    Articles: DFG German National Licenses
  15. 15
    Lousto, C.O. ; Sanchez, N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0550-3213
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0550-3213(91)90311-K

    Articles: DFG German National Licenses
  16. 16
    Sanchez, N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0550-3213
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0550-3213(87)90625-0

    Articles: DFG German National Licenses
  17. 17
    Sanchez, N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0550-3213
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0550-3213(86)90102-1

    Articles: DFG German National Licenses
  18. 18
    de Vega, H.J. ; Ramon-Medrano, M. ; Sanchez, N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0550-3213
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0550-3213(92)90360-N

    Articles: DFG German National Licenses
  19. 19
    De Vega, H.J. ; Sanchez, N.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0550-3213
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0550-3213(88)90374-4

    Articles: DFG German National Licenses
  20. 20
    Gasperini, M. ; Sanchez, N. ; Veneziano, G.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0550-3213
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0550-3213(91)90589-P

    Articles: DFG German National Licenses