Search Results - (Author, Cooperation:N. R. Wilson)

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  1. 1
    S. El-Boustani ; N. R. Wilson ; C. A. Runyan ; M. Sur
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-04-04
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Neural Inhibition/*physiology ; Neural Pathways/*physiology ; Neurons/*physiology ; Visual Cortex/*cytology/*physiology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    N. R. Wilson ; C. A. Runyan ; F. L. Wang ; M. Sur
    Nature Publishing Group (NPG)
    Published 2012
    Staff View
    Publication Date:
    2012-08-11
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Dendrites/metabolism ; Electrophysiology ; Interneurons/physiology ; Mice ; Models, Neurological ; Neural Inhibition/*physiology ; Neural Pathways/*physiology ; Neurons/*physiology ; Parvalbumins/metabolism ; Somatostatin/metabolism ; Visual Cortex/*cytology/*physiology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Suckling, A. J. ; Wilson, N. R. ; Rumsby, M. G.
    Springer
    Published 1982
    Staff View
    ISSN:
    1432-0533
    Keywords:
    Demyelination ; Multiple sclerosis ; EAE ; Virus infection
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Strain 13 guinea pigs, sensitised with spinal cord and Freund's complete adjuvant at 18–21 days of age, developed an experimental allergic encephalomyelitis (EAE) characterised by a non-fatal first attack followed by recovery, then remissions and relapses in the majority of animals. Pretreatment with an i.p. injection of an avirulent strain (A 774) of Semliki forest virus at 1 day of age resulted in an EAE with an accelerated onset and enhanced mortality during the first attack. Unlike the acute phase pathology in unpretreated animals, optic nerve demyelination was observed at 14 days after neuroantigen sensitisation. In sections of optic nerve from virus-treated animals, endothelial cell vesicularisation was seen and the role of this change in disease exacerbation is discussed. Virus treatments of animals older than 1 day of age resulted in a failure to potentiate the disease. Virus inoculated simultaneously with spinal cord alone failed to act as an adjuvent. The mechanism of virus action in modifying the immunopathogenesis of EAE and its relevance to multiple sclerosis is discussed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00691648

    Articles: DFG German National Licenses