Search Results - (Author, Cooperation:N. Lopez)
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1D.R. Nygren, B.J.P. Jones, N. López-March, Y. Mei, F. Psihas and J. Renner
Institute of Physics Publishing (IOP)
Published 2018Staff ViewPublication Date: 2018-03-22Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
2Staff View
Publication Date: 2018-07-19Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
3Bretones, G., Alvarez, M. G., Arango, J. R., Rodriguez, D., Nadeu, F., Prado, M. A., Valdes-Mas, R., Puente, D. A., Paulo, J. A., Delgado, J., Villamor, N., Lopez-Guillermo, A., Finley, D. J., Gygi, S. P., Campo, E., Quesada, V., Lopez-Otin, C.
American Society of Hematology (ASH)
Published 2018Staff ViewPublication Date: 2018-11-30Publisher: American Society of Hematology (ASH)Print ISSN: 0006-4971Electronic ISSN: 1528-0020Topics: BiologyMedicineKeywords: Lymphoid NeoplasiaPublished by: -
4Staff View
Publication Date: 2018-12-08Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
5X. S. Puente ; S. Bea ; R. Valdes-Mas ; N. Villamor ; J. Gutierrez-Abril ; J. I. Martin-Subero ; M. Munar ; C. Rubio-Perez ; P. Jares ; M. Aymerich ; T. Baumann ; R. Beekman ; L. Belver ; A. Carrio ; G. Castellano ; G. Clot ; E. Colado ; D. Colomer ; D. Costa ; J. Delgado ; A. Enjuanes ; X. Estivill ; A. A. Ferrando ; J. L. Gelpi ; B. Gonzalez ; S. Gonzalez ; M. Gonzalez ; M. Gut ; J. M. Hernandez-Rivas ; M. Lopez-Guerra ; D. Martin-Garcia ; A. Navarro ; P. Nicolas ; M. Orozco ; A. R. Payer ; M. Pinyol ; D. G. Pisano ; D. A. Puente ; A. C. Queiros ; V. Quesada ; C. M. Romeo-Casabona ; C. Royo ; R. Royo ; M. Rozman ; N. Russinol ; I. Salaverria ; K. Stamatopoulos ; H. G. Stunnenberg ; D. Tamborero ; M. J. Terol ; A. Valencia ; N. Lopez-Bigas ; D. Torrents ; I. Gut ; A. Lopez-Guillermo ; C. Lopez-Otin ; E. Campo
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-07-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: 3' Untranslated Regions/genetics ; Alternative Splicing/genetics ; B-Cell-Specific Activator Protein/biosynthesis/genetics ; B-Lymphocytes/metabolism ; Carrier Proteins/genetics ; Chromosomes, Human, Pair 9/genetics ; DNA Mutational Analysis ; DNA, Neoplasm/genetics ; Enhancer Elements, Genetic/genetics ; Genomics ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/*genetics/metabolism/pathology ; Mutation/*genetics ; Nerve Tissue Proteins/genetics ; Nuclear Proteins/genetics ; Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics ; Receptor, Notch1/genetics/metabolism ; Transcription Factors/geneticsPublished by: -
6R. Sabarinathan ; L. Mularoni ; J. Deu-Pons ; A. Gonzalez-Perez ; N. Lopez-Bigas
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-04-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Binding Sites ; DNA/*genetics/*metabolism ; *DNA Repair ; DNA, Neoplasm/genetics/metabolism ; DNA-Binding Proteins/*metabolism ; Gene Expression Regulation, Neoplastic/genetics ; Genome, Human/genetics ; Humans ; Lung Neoplasms/genetics ; Melanoma/*genetics ; Mutagenesis/*genetics ; *Mutation Rate ; Nucleosomes/genetics/metabolism ; Promoter Regions, Genetic/genetics ; Protein Binding ; Transcription Factors/*metabolismPublished by: -
7Staff View
Publication Date: 2018-02-01Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
8Staff View
Publication Date: 2018-10-11Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
9Staff View
Publication Date: 2018-10-02Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
10Staff View
Publication Date: 2018-10-16Publisher: Institute of Physics Publishing (IOP)Electronic ISSN: 1748-0221Topics: PhysicsPublished by: -
11N. Lopez ; D. J. Graham ; R. McGuire, Jr. ; G. E. Alliger ; Y. Shao-Horn ; C. C. Cummins ; D. G. Nocera
American Association for the Advancement of Science (AAAS)
Published 2012Staff ViewPublication Date: 2012-01-28Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
12SANTACANA, J. A. ; CONROY, D. A. ; MUJICA, M. E ; MARÍN, C. ; LÓPEZ, N.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1365-2761Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0300-9629Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0021-9614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
15Haffajee, A. D. ; Bogren, A. ; Hasturk, H. ; Feres, M. ; Lopez, N. J. ; Socransky, S. S.
Oxford, UK : Munksgaard International Publishers
Published 2004Staff ViewISSN: 1600-051XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background: Most clinical studies assume that the subgingival microbiota is similar from one geographic location to another. The purpose of the present investigation was to examine the composition of the subgingival microbiota in chronic periodontitis subjects from four countries.Method: Subjects with chronic periodontitis (N, Sweden=101; USA=115; Brazil=58; Chile=26) were recruited. Subjects were measured at baseline for plaque, gingivitis, bleeding on probing (BOP), suppuration, pocket depth (PD) and attachment level (AL) at six sites per tooth. Subgingival plaque samples taken from the mesial aspect of each tooth at baseline were individually analyzed for their content of 40 bacterial species using checkerboard DNA–DNA hybridization (total samples=6036). % DNA probe counts comprised by each species was determined for each site and averaged across sites in each subject. Significance of differences in proportions of each species among countries was determined using ancova adjusting for age, mean pocket depth, gender and smoking status. p-Values were adjusted for multiple comparisons.Results: On average, all species were detected in samples from subjects in the four countries. Thirteen species differed significantly in adjusted mean proportions among countries even after adjusting for multiple comparisons. Porphyromonas gingivalis, one species that differed in proportions among countries, comprised adjusted means of 7.5, 11.9, 1.6 and 6.6% of the microbiota in subjects from Brazil, Chile, Sweden and USA (p〈0.001), while mean proportions of Treponema denticola were 6.7, 4.2, 0.8 and 2.3, respectively (p〈0.001). In contrast, a key periodontal pathogen, Tannerella forsythensis, exhibited mean proportions ranging from 6.2–8.5% and did not differ significantly among countries. Besides these species, prominent species in Brazil were Actinomyces naeslundii genospecies 1 and 2 (8.4%, 7.2%) and Prevotella intermedia (6.5%); in Chile, Prevotella melaninogenica (6.4%) and Neisseria mucosa (5.3%); in Sweden A. naeslundii genospecies 2 (8.4%), Capnocytophaga gingivalis (7.1%) and Peptostreptococcus micros (5.0%); in USA A. naeslundii genospecies 2 (7.5%), P. intermedia (6.8%) and C. gingivalis (6.1%).Conclusions: The microbial profiles of subgingival plaque samples from chronic periodontitis subjects in four countries showed surprisingly marked differences. These differences persisted after adjusting for age, mean pocket depth, gender and smoking status.Type of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 1432-1793Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract A population of the regular sea urchin Lytechinus variegatus was sampled, and the gonad volume and test diameter recorded at monthly intervals for 10 years. Parameters abstracted from the data included the size and date when the gonads were full and when they were spent, the spawning pattern, and the spawn output. Environmental parameters available were sea temperature and rainfall. Correlations were determined among these. A correlation was also found between the appearance in successive years of a brood of young urchins on the shore and the temperature and rainfall.Type of Medium: Electronic ResourceURL: -
17González-Reimers, E. ; Santolaria-Fernández, F. ; Moreno-García, A. ; Batista-López, N. ; Rodríguez-Moreno, F.
Springer
Published 1993Staff ViewISSN: 1824-3096Keywords: Ethanol consumption Harris linesSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Harris lines represent episodes of growth arrest followed by recovery, thus reflecting episodes of mismatched imbalance between energy intake and energy expenditure. Consumption of ethanol during the growth period — formerly extended in our wine-producing rural areas- may lead to such a situation, due at least in part to the energy-wasteful MEOS-linked ethanol metabolism. Based on these facts, in the present study we have analysed the relationship between ethanol intake during growth period and the presence of Harris lines in the right tibia in 100 consecutive adult patients admitted to our hospitalization unit. Early ethanol consumption was strongly related with the presence of two or more, and three or more Harris lines, so that ethanol consumption should be considered in the differential diagnosis of Harris lines, and conversely, the presence of Harris lines point to ethanol consumption during growth period. This association was independent from coexisting starvation and/or illness.Type of Medium: Electronic ResourceURL: -
18Staff View
ISSN: 1572-8897Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyMathematicsNotes: Abstract A non-linear neural network model to perform cluster analysis is presented. It provides an efficient parallel algorithm for solving this pattern recognition task, consisting, from the mathematical point of view, of a combinatorial optimization problem. A new classification technique is discussed in order to visualize clustering patterns within a molecular set, by means of numerical analysis of the similarity matrix. As an example of the application of the reported neural network model, a quantum molecular similarity study in the field of structure-activity relationships is reported. A molecular set made of eighteen quinolones is used as an example. The resultant cluster distribution showed a good qualitative correlation between similarity data and biological activity.Type of Medium: Electronic ResourceURL: -
19Leyva-Lopez, N. E. ; Vasco, N. ; Barba de la Rosa, A. P. ; Paredes-Lopez, O.
Springer
Published 1995Staff ViewISSN: 1573-9104Keywords: Amaranth ; Seeds ; Storage proteinsSource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract Acetone and hexane were used to know the effect of defatting amaranth flour on the extraction yield of protein fractions and on the electrophoretic patterns. It was found that albumins (33%) and globulins (20%) did not present yield changes when using these two solvents, but it was noted that with hexane compared to acetone, prolamins extraction was reduced by half (3.0 to 1.6%) whereas glutelins increased from 26.5 to 30%. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) patterns of prolamins extracted with acetone and hexane showed one band of low molecular weight (22 KDa) and five bands between 52 to 22 KDa, respectively. No electrophoretic changes were observed in the remaining fractions.Type of Medium: Electronic ResourceURL: -
20González-Reimers, E. ; Arnay-de-la-Rosa, M. ; Galindo-Martin, L. ; Batista-López, N. ; Navarro-Mederos, J. F. ; Castro-Alemán, V. V. ; Santolaria-Fernández, F.
Springer
Published 1991Staff ViewISSN: 1824-310XKeywords: Paleontutrition ; Bone histology ; Trace elements ; Sr ; Mg ; Mn ; Zn ; Cu ; Fe ; Co ; Prehispanic Canarians ; OsteoporosisSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract The trabecular bone mass (TBM) of 29 bone cylinders (obtained at the iliac crest with a Bordier's trephine) belonging to non-sanile adult skeletons of the prehispanic inhabitants of the Western Canary Islands was determined histomorphometrically. Scanbning electron microscope and/or binocular microscope observations of the cylinders were also performed in order to exclude diagenetic alterations of the bones. Bone content of Sr, Mg, Mn, Co, Cu, Fe and Zn of the skeletons and of soil samples from the burials where they were found were also measured. These procedures were also performed in a control group of 21 preciously healthy individuals dead as a result of trauma. Although mean TBM values of the prehispanic samples not different from those of the control group, some individual TBM values of skeletons from La Palma and El Hierro were fully in the osteoporotic range. Individuals from La Palma and El Hierro showed high mean Sr, Mg and Mn bone contents, whereas Zn and Fe contents were below the normal range, indicating a mainly vegetarian diet. Individuals from Tenerife showed nearly normal Sr and Mg bone contents, low Zn and higher Fe values than those from the other islands; these results indicate a more mixed diet. No relationship was found between TBM and bone trace element contents.Type of Medium: Electronic ResourceURL: