Search Results - (Author, Cooperation:N. Irie)

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  1. 1
    R. E. Green ; E. L. Braun ; J. Armstrong ; D. Earl ; N. Nguyen ; G. Hickey ; M. W. Vandewege ; J. A. St John ; S. Capella-Gutierrez ; T. A. Castoe ; C. Kern ; M. K. Fujita ; J. C. Opazo ; J. Jurka ; K. K. Kojima ; J. Caballero ; R. M. Hubley ; A. F. Smit ; R. N. Platt ; C. A. Lavoie ; M. P. Ramakodi ; J. W. Finger, Jr. ; A. Suh ; S. R. Isberg ; L. Miles ; A. Y. Chong ; W. Jaratlerdsiri ; J. Gongora ; C. Moran ; A. Iriarte ; J. McCormack ; S. C. Burgess ; S. V. Edwards ; E. Lyons ; C. Williams ; M. Breen ; J. T. Howard ; C. R. Gresham ; D. G. Peterson ; J. Schmitz ; D. D. Pollock ; D. Haussler ; E. W. Triplett ; G. Zhang ; N. Irie ; E. D. Jarvis ; C. A. Brochu ; C. J. Schmidt ; F. M. McCarthy ; B. C. Faircloth ; F. G. Hoffmann ; T. C. Glenn ; T. Gabaldon ; B. Paten ; D. A. Ray
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-12-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Alligators and Crocodiles/classification/*genetics ; Animals ; Biological Evolution ; Birds/classification/*genetics ; Conserved Sequence ; DNA Transposable Elements ; Dinosaurs/classification/*genetics ; *Evolution, Molecular ; Genetic Variation ; *Genome ; Molecular Sequence Annotation ; Molecular Sequence Data ; Phylogeny ; Reptiles/classification/genetics ; Sequence Alignment ; Sequence Analysis, DNA ; Transcriptome
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Saji, M. ; Fujii, K. ; Ohkuni, H. ; Irie, N. ; Osono, E. ; Kato, F.
    Springer
    Published 2000
    Staff View
    ISSN:
    1437-7780
    Keywords:
    Key words Acrinol ; Tetracycline hydrochloride ; Pseudomonas aeruginosa ; Synergistic effect
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Combined treatment of acrinol (Ac) and tetracycline hydrochloride (Tc) against Pseudomonas aeruginosa strains isolated from clinical specimens synergistically increased the bactericidal effect. The minimum bactericidal concentration (MBC) of Ac against P. aeruginosa strain no. 985 was 200 μg/ml, while the MBC of Ac against strains no. 47 and no. 783 was above 800 μg/ml for each. The MBC of Tc was above 400 μg/ml against each of the tested strains. However, simultaneous treatment with 25 μg/ml Ac and 200 μg/ml Tc against P. aeruginosa strain no. 985 decreased the viable cell number from 107 cfu/ml to 〈10 cfu/ml within 24 h, while a higher concentration of Tc (400 μg/ml) with Ac (25 μg/ml) reduced the viable cell number to 〈10 cfu/ml within 8 h. A similar synergistic bactericidal effct of Ac and Tc was observed in strains no. 47 and no. 783 by treatment with 200 μg/ml Ac and 200 μg/ml or 400 μg/ml Tc. The degree of bactericidal effect against P. aeruginosa was proportional to the concentration of Tc under the condition of a constant concentration of Ac. Furthermore, Ac-treated cells of strain no. 47 were killed by a following Tc treatment, but cells pretreated with Tc did not show such a sensitivity to Ac. To induce the synergistic effect of Ac and Tc, Ac must be applied to P. aeruginosa before or at the same time as Tc.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/PL00012157

    Articles: DFG German National Licenses