Search Results - (Author, Cooperation:N. Habib)

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  1. 1
    N. Rhind ; Z. Chen ; M. Yassour ; D. A. Thompson ; B. J. Haas ; N. Habib ; I. Wapinski ; S. Roy ; M. F. Lin ; D. I. Heiman ; S. K. Young ; K. Furuya ; Y. Guo ; A. Pidoux ; H. M. Chen ; B. Robbertse ; J. M. Goldberg ; K. Aoki ; E. H. Bayne ; A. M. Berlin ; C. A. Desjardins ; E. Dobbs ; L. Dukaj ; L. Fan ; M. G. FitzGerald ; C. French ; S. Gujja ; K. Hansen ; D. Keifenheim ; J. Z. Levin ; R. A. Mosher ; C. A. Muller ; J. Pfiffner ; M. Priest ; C. Russ ; A. Smialowska ; P. Swoboda ; S. M. Sykes ; M. Vaughn ; S. Vengrova ; R. Yoder ; Q. Zeng ; R. Allshire ; D. Baulcombe ; B. W. Birren ; W. Brown ; K. Ekwall ; M. Kellis ; J. Leatherwood ; H. Levin ; H. Margalit ; R. Martienssen ; C. A. Nieduszynski ; J. W. Spatafora ; N. Friedman ; J. Z. Dalgaard ; P. Baumann ; H. Niki ; A. Regev ; C. Nusbaum
    American Association for the Advancement of Science (AAAS)
    Published 2011
    Staff View
    Publication Date:
    2011-04-23
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Centromere/genetics/physiology/ultrastructure ; DNA Transposable Elements ; Evolution, Molecular ; Gene Expression Profiling ; Gene Expression Regulation, Fungal ; Genes, Mating Type, Fungal ; *Genome, Fungal ; Genomics ; Glucose/metabolism ; Meiosis ; Molecular Sequence Annotation ; Molecular Sequence Data ; Phylogeny ; RNA, Antisense/genetics ; RNA, Fungal/genetics ; RNA, Small Interfering/genetics ; RNA, Untranslated/genetics ; Regulatory Elements, Transcriptional ; Schizosaccharomyces/*genetics/growth & development/metabolism ; Schizosaccharomyces pombe Proteins/genetics/metabolism ; Sequence Analysis, DNA ; Species Specificity ; Transcription Factors/genetics/metabolism ; Transcription, Genetic
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2014-12-11
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    CRISPR-Associated Proteins/genetics/metabolism ; CRISPR-Cas Systems/*genetics ; Cell Line, Tumor ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; DNA, Complementary/biosynthesis/genetics ; Drug Resistance, Neoplasm/drug effects/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Gene Library ; Genetic Engineering/*methods ; Genetic Loci/genetics ; Genetic Testing ; Genome, Human/*genetics ; Humans ; Indoles/pharmacology ; Melanoma/drug therapy/*genetics ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors ; RNA, Untranslated/biosynthesis/genetics/metabolism ; Reproducibility of Results ; Sulfonamides/pharmacology ; Transcriptional Activation/*genetics ; Up-Regulation/genetics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    L. Cong ; F. A. Ran ; D. Cox ; S. Lin ; R. Barretto ; N. Habib ; P. D. Hsu ; X. Wu ; W. Jiang ; L. A. Marraffini ; F. Zhang
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-01-05
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Base Sequence ; Caspase 9/*chemistry/genetics ; DNA/chemistry/genetics ; *DNA Cleavage ; Genetic Engineering/*methods ; Genetic Loci ; Genome/*genetics ; Humans ; Inverted Repeat Sequences/*genetics ; Mice ; Microarray Analysis/*methods ; Molecular Sequence Data ; Mutagenesis ; RNA/chemistry/genetics ; Recombinational DNA Repair ; Streptococcus pyogenes/enzymology/genetics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    ISSN:
    1434-4475
    Keywords:
    4-Amino-5-carbamoylthiazoles ; Thiazolo[4,5-d]pyrimidines
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Description / Table of Contents:
    Zusammenfassung Einige 3-substituierte 2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one (2a,b;4) wurden hergestellt und zu 7-Chloro- (3,5), 7-Diethanolamino- (6a,b), 7-bis(2-Chloroethyl) amino- (7), 7-Azido- (8), 7-Amino- (9), 7-Hydrazino- (10), 7-Mercapto- (11a,b) und 7-Dimethyl-thioderivaten (12a,b) umgesetzt. Diese Verbindungen wurden auf ihrein vitro antimikrobiellen, anti-HIV und anticancerogenen Aktivitäten geprüft.
    Notes:
    Summary Some 3-substituted 2-thioxothiazolo[4,5-d]pyrimidin-7(6H)-ones (2a,b;4) have been synthesized and converted to their 7-chloro (3,5), 7-diethanolamino (6a,b), 7-bis(2-chloroethyl)amino (7), 7-azido (8), 7-amino (9), 7-hydrazino (16), 7-mercapto (11a,b), and 7-methylthio (12) derivatives. These compounds were evaluated for theirin vitro antimicrobial, anti-HIV; and anticancer activities.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00844697

    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1434-4475
    Keywords:
    Thiazolo[4,5-d]pyrimidines
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Description / Table of Contents:
    Zusammenfassung Die Synthese von 5-Mercapto-3-phenyl-2-thioxo-2,3-dihydrothiazolo[4,5-d-pyrimidin-7(6H)-on (2) und seiner 5,7-dichloro-(3), 5,7-diazido-(4), 5,7-dimanio-(5), 5,7-dimercapto-(6), 5,7-dimethylthio- (7) und 6-methyl-5-methylthio-Derivaten (8) wird beschrieben. Die hergestellten Verbindungen wurden auf ihrein vitro anti-HIV, anticancerogenen, antibakteriellen und antimykotischen Aktivitäten geprüft.
    Notes:
    Summary A convenient and simple synthesis of 5-mercapto-3-phenyl-2-thioxo-2,3-dihydrothiazolo-[4,5-d]pyrimidin-7(6H-one(2) and its 5,7-dichloro (3), 5,7-diazido (4), 5,7-diamino (5), 5,7-dimerapto (6), 5,7-dimethylthio (7), and 6-methyl-5-methylthio (8) derivatives is described. The prepared compounds were screened for theirin vitro anti-HIV, anticancer, antibacterial and antifungal activities.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00844696

    Articles: DFG German National Licenses
  6. 6
    Staff View
    ISSN:
    1432-1262
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract A radioimmunoassay was used for the detection of the human carcinoma-associated antigen CA-50 in the serum of 50 normal subjects, 16 patients with inflammatory bowel diseases and 77 patients with primary and secondary colorectal carcinomas. Serum levels in all normal patients and those with benign disease were below 17 U/ml, while 40 of 77 (51%) patients with carcinoma had levels above 17 U/ml. The sensitivity of this test was 22% for Dukes' A carcinoma, 29% for Dukes' B, 59% for Dukes' C and 73% for metastatic disease. The CA-50 levels were elevated in 7 of 9 (78%) patients who developed tumour recurrence following curative surgery compared with 15 of 43 (35%) patients who are alive and tumour free (p〈0.05). Therefore, this test may prove useful in the diagnosis and prognosis of patients with colorectal carcinomas.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01648448

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0040-4020
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/S0040-4020(01)88495-7

    Articles: DFG German National Licenses
  8. 8
    Staff View
    ISSN:
    0165-4608
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0165-4608(91)90514-U

    Articles: DFG German National Licenses
  9. 9
    Nagy, M. R. ; El-Salam, F. Abd ; Habib, N. D. ; Kamel, R.
    Springer
    Published 1981
    Staff View
    ISSN:
    1572-9486
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Physics
    Notes:
    Abstract Transient creep of pure and commercial aluminium was studied under a constant stress of 18·6 MPa at different temperatures ranging from 613 to 698 K. The anomalous values of transient creep parametersβ, n ranging from 0·003–0·055 (±0·001) and 0·5–1·0 (±0·05) respectively, which were found in this temperature rangs, might bs ascribed to the superplastic behaviour of pure and commercial aluminium. The activation energy of transient creep for pure Al was found to be about (2·4 +0·07) × 10−22) kJ/atom. characterizing a dislocation glide-cross slipping mechanism.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01603791

    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1432-1262
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract Our previous studies have demonstrated a desaturation of stearic acid related to oleic acid in the lipid layer of erythrocytes in patients with malignancies. This study investigated the stearic acid desaturation in red blood cell membranes of rats during the induction of colorectal tumours. Male Sprague-Dawley rats were injected weekly with dimethylhydrazine (DMH) and sacrificed at 4-week intervals. Blood was withdrawn via heart puncture, collected in EDTA bottle and erythrocytes separated by centrifugation. Total lipid extraction was carried out and analysed with gas liquid chromatography. In the control rats (injected with normal saline) the mean of the stearic to oleic acid ratio in erythrocyte membranes was 2.0±0.3 (n=28, range 1.51–2.62) compared to a mean of 0.94±0.16 (n=0.5–1.23) in tumour bearing rats (p〈 0.001). The increased desaturation occurred in parallel with appearance of tumours. These data suggest the regulation of stearic acid desaturation is an important adaptive mechanism of membrane fluidity and could be a useful chemical marker for malignancy.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF01648990

    Articles: DFG German National Licenses
  11. 11
    Graiss, G. ; Shinoda, R. ; Habib, N.
    Springer
    Published 1991
    Staff View
    ISSN:
    1573-4803
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes:
    Abstract A study has been made of an internal friction peak which occurs due to the precipitation of Guinier-Preston zones from two supersaturated Al-Ag alloys. The peak observed was interpreted as being due to relaxation around the zones of different elastic constants from that of the Al matrix. Differences in internal friction characteristics between specimens heated at 100 and 200 °C were attributed to the reversion process occurring around 200 °C in pure alloy. The height of the relaxation peak and the level of internal friction background were found to be highly affected by the presence of Fe and Si impurities in the doped alloy.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00557162

    Articles: DFG German National Licenses