Search Results - (Author, Cooperation:N. Goodwin)

2011-03-18

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Alprostadil/pharmacology ; Benzimidazoles/pharmacology ; Calcium/*metabolism ; Calcium Channel Blockers/pharmacology ; Calcium Channels/*metabolism ; Calcium Signaling/*drug effects ; Cyclic AMP ; Cyclopropanes/pharmacology ; Electric Conductivity ; Humans ; Hydrogen-Ion Concentration ; Male ; Mibefradil/pharmacology ; Naphthalenes/pharmacology ; Patch-Clamp Techniques ; Progesterone/metabolism/*pharmacology ; Spermatozoa/*drug effects/*metabolism

2018-05-22

The American Association of Immunologists (AAI)

0022-1767

1550-6606

Medicine

2018-11-20

The American Association of Immunologists (AAI)

0022-1767

1550-6606

Medicine

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

The effect of breathing 0.1 minimum alveolar concentrations (MAC) of desflurane or isoflurane for three minutes on the incidence of adverse airway events on a subsequent breath of 2 MAC was investigated. Twenty-five volunteers known to develop an adverse airway event to desflurane or isoflurane took part in the study. Each volunteer was exposed to isoflurane and desflurane at least 24 h apart. Volunteers were assessed for adverse airway events while breathing 2 MAC inhalational anaesthetic following breathing 100% O2 for 3 min. This was repeated with 0.1 MAC inhalational anaesthetic in oxygen instead of 100% O2. Adverse airway events decreased from 88% to 40% when tests were conducted with desflurane (p = 0.002). With isoflurane, the reduction from 60% to 52% was not statistically significant (p = 0.774). Breathing low concentrations of desflurane decreases the incidence of adverse airway events on subsequent inhalation of higher concentration of desflurane.

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Summary We examined the use of the 30° rigid nasendoscope in aiding difficult tracheal intubations. A Cormack and Lehane grade 4 difficult intubation (no view of glottis or epiglottis) was set up on a manikin. After 10 s of tuition, 40 anaesthetists attempted to pass a standard gum elastic bougie between the cords, with and without the nasendoscope, in randomised order. A bougie curved to an ‘optimal curve’ was also tested. Using the standard bougie 13/40 (33%) passed the bougie between the cords without the nasendoscope, compared with 31/40 (78%) when using the nasendoscope (p 〈 0.001). The ‘optimal curve’ bougie resulted in 29/40 (73%) and 39/40 (98%) success rates without and with the nasendoscope, respectively (p = 0.004). The nasendoscope is a simple and easy to use tool in grade 4 intubation, and results are improved further by the use of an ‘optimal curve’ bougie.

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Sevoflurane is a non-pungent volatile anaesthetic agent with a low blood-gas solubility coefficient. It has been studied in concentrations of up to 8% for induction of anaesthesia. Previous work has suggested that there may be a ceiling effect with increasing concentration of sevoflurane above 6%, but there are no published studies using 12% sevoflurane. This study compared 8 and 12% sevoflurane to induce anaesthesia in adults. Sevoflurane was administered using two adapted datum vaporisers with the interlock removed. Induction with 12% sevoflurane compared to 8% sevoflurane produced a significant decrease in the time to achieve central pupils, corresponding to surgical anaesthesia and the third part of Guedel's stage 3 of anaesthesia (mean time (SD) 201 s (81) and 247 s (39), respectively, p 〈 0.05). Twelve-percent sevoflurane produced a similar stable cardiovascular profile to 8% sevoflurane, and there was no increase in respiratory complications.

Electronic Resource

0921-8009

Hope ; Malthusian pessimist ; No-growth ; Prediction ; Sustainable development ; Technological optimist

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Energy, Environment Protection, Nuclear Power Engineering

Economics

Electronic Resource

1365-2044

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Electronic Resource

1573-7551

Computer-supported writing ; collaborative editing ; collaborative writing ; cooperative work ; group communication

Springer Online Journal Archives 1860-2000

Computer Science

Abstract This paper documents the results of a field test of Instant Update, a collaborative writing tool by a geographically dispersed department at the MITRE Corporation. Thirty-six participants were given Instant Update software and free training and support in exchange for their cooperation with data collection. These participants spent a great deal of time writing and communicating with each other about their written work. They began the pilot test with enthusiasm, using Instant Update for many types of documents and anticipating many benefits. After three months of experience they rated the actual benefits they received from the software lower than they had expected. Their usage became much more refined. They continued to use it for some types of documents, but stopped for others. The collaborative writing software was used successfully to create joint documents that have a consistent format and are produced on a regular basis (such as weekly activity reports) and for documents that provide access to shared information (such as a vacation calendar). It was used less successfully for the production of documents that require a complex work flow and have a changing group of contributors. We concluded that although collaborative writing is difficult to support and the currently available collaborative writing tools need to be improved before they can meet the needs of most co-writers, they are adequate for some types of tasks. Documents that are well defined and are created by experienced users who can cooperate well can benefit from the currently available tools.

Electronic Resource