Search Results - (Author, Cooperation:N. Cockett)

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  1. 1
    Y. Jiang ; M. Xie ; W. Chen ; R. Talbot ; J. F. Maddox ; T. Faraut ; C. Wu ; D. M. Muzny ; Y. Li ; W. Zhang ; J. A. Stanton ; R. Brauning ; W. C. Barris ; T. Hourlier ; B. L. Aken ; S. M. Searle ; D. L. Adelson ; C. Bian ; G. R. Cam ; Y. Chen ; S. Cheng ; U. DeSilva ; K. Dixen ; Y. Dong ; G. Fan ; I. R. Franklin ; S. Fu ; P. Fuentes-Utrilla ; R. Guan ; M. A. Highland ; M. E. Holder ; G. Huang ; A. B. Ingham ; S. N. Jhangiani ; D. Kalra ; C. L. Kovar ; S. L. Lee ; W. Liu ; X. Liu ; C. Lu ; T. Lv ; T. Mathew ; S. McWilliam ; M. Menzies ; S. Pan ; D. Robelin ; B. Servin ; D. Townley ; W. Wang ; B. Wei ; S. N. White ; X. Yang ; C. Ye ; Y. Yue ; P. Zeng ; Q. Zhou ; J. B. Hansen ; K. Kristiansen ; R. A. Gibbs ; P. Flicek ; C. C. Warkup ; H. E. Jones ; V. H. Oddy ; F. W. Nicholas ; J. C. McEwan ; J. W. Kijas ; J. Wang ; K. C. Worley ; A. L. Archibald ; N. Cockett ; X. Xu ; B. P. Dalrymple
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-06-07
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Amino Acid Sequence ; Animals ; Fatty Acids, Volatile/metabolism/physiology ; Gene Expression Regulation ; Genome ; Keratins, Hair-Specific/genetics ; Lipid Metabolism/genetics/*physiology ; Molecular Sequence Data ; Phylogeny ; Rumen/metabolism/*physiology ; Sheep, Domestic/classification/*genetics/*metabolism ; Transcriptome ; Wool/growth & development
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    ISSN:
    1744-313X
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    Polymorphism of the bovine DRB, DQA, DQB, DYA, DOB and DIB genes was investigated using restriction fragment length polymorphism (RFLP) analysis, isoelectric focusing (IEF), class II serology and polymerase chain reaction (PCR) based typing techniques. The simultaneous application of multiple typing techniques and the characterization of multiple genes resulted in a greatly enhanced picture of the bovine class II regions. Thirty-eight class IIa (DR-DQ) and 5 class lib (DYA-DOB-DIB) haplotypes were defined. It was found that IEF types were associated with DRB3 polymorphism defined by DRB3 PCR-RFLP and DRB3 microsatellite PCR. Serologically defined polymorphism was associated with distinct molecular/IEF motifs and, therefore, DR and DQ specificities could be tentatively distinguished. Although the DR and DQ genes are tightly linked, neither DR nor DQ typing defined all of the class IIa region polymorphism. Furthermore, even the most powerful DRB3 typing technique, DRB3 PCR-RFLP, failed to detect all expressed DRB3 polymorphism. All detected DRB3 polymorphism could, however, be distinguished with a combination of two molecular techniques: DRB3 PCR-RFLP and DRB3 microsatellite PCR. RFLP typing with transmembrane probes detected significantly less polymorphism than typing with cDNA or exon probes. However, the transmembrane probes were useful because they were locus specific. The presence of only 5 of 12 possible class lib haplotypes was unexpected and indicates that the DYA, DOB and DIB genes are tightly linked.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1744-313X.1994.tb00198.x

    Articles: DFG German National Licenses