Search Results - (Author, Cooperation:N. Buckley)
-
1L. Borysiewicz ; N. Buckley
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-03-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Great Britain ; *Holidays ; *Science ; *UniversitiesPublished by: -
2M. Caskey ; F. Klein ; J. C. Lorenzi ; M. S. Seaman ; A. P. West ; N. Buckley ; G. Kremer ; L. Nogueira ; M. Braunschweig ; J. F. Scheid ; J. A. Horwitz ; I. Shimeliovich ; S. Ben-Avraham ; M. Witmer-Pack ; M. Platten ; C. Lehmann ; L. A. Burke ; T. Hawthorne ; R. J. Gorelick ; B. D. Walker ; T. Keler ; R. M. Gulick ; G. Fatkenheuer ; S. J. Schlesinger ; M. C. Nussenzweig
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-03-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
3M. Caskey ; F. Klein ; J. C. Lorenzi ; M. S. Seaman ; A. P. West, Jr. ; N. Buckley ; G. Kremer ; L. Nogueira ; M. Braunschweig ; J. F. Scheid ; J. A. Horwitz ; I. Shimeliovich ; S. Ben-Avraham ; M. Witmer-Pack ; M. Platten ; C. Lehmann ; L. A. Burke ; T. Hawthorne ; R. J. Gorelick ; B. D. Walker ; T. Keler ; R. M. Gulick ; G. Fatkenheuer ; S. J. Schlesinger ; M. C. Nussenzweig
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-04-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Amino Acid Sequence ; Antibodies, Monoclonal/administration & ; dosage/immunology/pharmacokinetics/therapeutic use ; Antibodies, Neutralizing/administration & dosage/adverse ; effects/*immunology/pharmacology/therapeutic use ; Antigens, CD4/metabolism ; Binding Sites ; Case-Control Studies ; Evolution, Molecular ; Female ; HIV Antibodies/administration & dosage/adverse ; HIV Envelope Protein gp120/chemistry/immunology ; HIV Infections/immunology/*therapy/virology ; HIV-1/chemistry/drug effects/*immunology ; Humans ; Immunization, Passive/methods ; Male ; Middle Aged ; Molecular Sequence Data ; Time Factors ; Viral Load/drug effects/*immunology ; Viremia/immunology/*therapy/virology ; Young AdultPublished by: -
4Staff View
ISSN: 0022-0728Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
5Peacock, A., Larance, B., Farrell, M., Cairns, R., Buckley, N., Degenhardt, L.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-03-25Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, AddictionPublished by: -
6Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The three fungi were grown at different temperatures and for various times on a reciprocal shaker, with 100 ml. of Czapek's Dox medium in 1 1. flasks to ensure adequate aeration. At the end of the growing period the medium was checked to ensure that there was no contamination. The mycelium was ...Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0009-8981Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicineType of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1432-2013Keywords: Contraction Velocity ; Force-Frequency Relationship ; Human Myocardium ; Relaxation VelocitySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Contractile responses to increased stimulation frequency were analyzed in isolated papillary and ventricular muscle bundles from human, guinea pig and rat hearts. Contractile tension and velocity of tension development and release were recorded while changes in frequency were made. The following were calculated for each frequency; duration of the phases of accelerating (I) and decelerating (II) contraction, and accelerating (III) and decelerating (IV) relaxation; tension at end of phases I, II and III; and instantaneous velocities at the midpoint of phase I, and at the end of phases I and III. Increasing frequency was accompanied by decreased contractile tension and velocities to a limit in rat and markedly hypertrophied adult human myocardium; but by increased contractile tension and velocities to a limit in guinea pig, late fetal human, and minimally hypertrophied adult human myocardium. The observations support the hypothesis that peak contractile tension development depends on phase I velocity and phase II duration.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1432-2013Keywords: Force-Frequency Relationship ; Temperature ; Human Myocardium ; Extracellular CalciumSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary The effects of temperature and calcium on force-frequency relationships in mammalian ventricular myocardium were studied in isolated papillary and ventricular muscle bundles. Tensions, velocities, and phase durations were determined from the isometric tension record and its first derivative. Decreasing bath temperature from 34–36°C to 27–31°C increased contractile tension and prolonged the phases of contraction in rat, guinea pig, and adult and fetal human tissues without altering the force-frequency relationship. Doubling extracellular [Ca++] beyond the 2.7 mM control for human tissue increased contractile tension and shortened phase I, and made the force-frequency relationship less steep or biphasic. These results suggest that the negative force-frequency relationship in the failing human heart cannot be explained merely on the basis on unavailability of Ca++ to the contractile proteins.Type of Medium: Electronic ResourceURL: -
10Spiegel, S. ; Carlson, R. O. ; Olivera, A. ; Buckley, N. E. ; Mattie, M. E. ; Masco, D. ; Brooker, G.
Springer
Published 1993Staff ViewISSN: 1573-4986Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1573-8221Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Summary A study was made of the effect produced by nucleosides (uridine, inosine and bases included into their composition—uracil and hypoxanthine) on the development of fatigue in the myocardium. The latter process was induced in acute experimental conditions by repeated overloading of the left cardiac ventricle by complete occlusion of the ascending aorta for 30 sec. The interval between the occlusions was 5 min. The maximal systolic pressure observed during aortic compression decreased with each subsequent compression, notwithstanding the unchanged or rising endodiastolic pressure. The dynamics of reduction of the maximal level of cardiac contractile function characterizes the process of fatigue. Administration of uridine, inosine and hypoxanthine following the fifth compression inhibits the further development of the fatigue process; the same effect is produced by strophanthin. Administration of a combination of uridine, uracil inosine, hypoxanthine and strophanthin eliminated the fatigue phenomena and increased the maximal level of the cardiac contractile function to a greater degree and for a longer time than separate administration of the same agents.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1573-8221Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineType of Medium: Electronic ResourceURL: