Search Results - (Author, Cooperation:N. Buckley)

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  1. 1
    L. Borysiewicz ; N. Buckley
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-03-01
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Great Britain ; *Holidays ; *Science ; *Universities
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2016-03-24
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2015-04-10
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adult ; Amino Acid Sequence ; Antibodies, Monoclonal/administration & ; dosage/immunology/pharmacokinetics/therapeutic use ; Antibodies, Neutralizing/administration & dosage/adverse ; effects/*immunology/pharmacology/therapeutic use ; Antigens, CD4/metabolism ; Binding Sites ; Case-Control Studies ; Evolution, Molecular ; Female ; HIV Antibodies/administration & dosage/adverse ; HIV Envelope Protein gp120/chemistry/immunology ; HIV Infections/immunology/*therapy/virology ; HIV-1/chemistry/drug effects/*immunology ; Humans ; Immunization, Passive/methods ; Male ; Middle Aged ; Molecular Sequence Data ; Time Factors ; Viral Load/drug effects/*immunology ; Viremia/immunology/*therapy/virology ; Young Adult
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    N. Buckley, A. ; Kennedy, B.J.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-0728
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Staff View
    Publication Date:
    2018-03-25
    Publisher:
    BMJ Publishing
    Electronic ISSN:
    2044-6055
    Topics:
    Medicine
    Keywords:
    Open access, Addiction
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    BUCKLEY, N. G. ; PUGH, G. J. F.

    [s.l.] : Nature Publishing Group
    Published 1971
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] The three fungi were grown at different temperatures and for various times on a reciprocal shaker, with 100 ml. of Czapek's Dox medium in 1 1. flasks to ensure adequate aeration. At the end of the growing period the medium was checked to ensure that there was no contamination. The mycelium was ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Buckley, N. ; Burkoth, T.L.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-8981
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Buckley, N. M. ; Penefsky, Z. J. ; Litwak, R. S.
    Springer
    Published 1972
    Staff View
    ISSN:
    1432-2013
    Keywords:
    Contraction Velocity ; Force-Frequency Relationship ; Human Myocardium ; Relaxation Velocity
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary Contractile responses to increased stimulation frequency were analyzed in isolated papillary and ventricular muscle bundles from human, guinea pig and rat hearts. Contractile tension and velocity of tension development and release were recorded while changes in frequency were made. The following were calculated for each frequency; duration of the phases of accelerating (I) and decelerating (II) contraction, and accelerating (III) and decelerating (IV) relaxation; tension at end of phases I, II and III; and instantaneous velocities at the midpoint of phase I, and at the end of phases I and III. Increasing frequency was accompanied by decreased contractile tension and velocities to a limit in rat and markedly hypertrophied adult human myocardium; but by increased contractile tension and velocities to a limit in guinea pig, late fetal human, and minimally hypertrophied adult human myocardium. The observations support the hypothesis that peak contractile tension development depends on phase I velocity and phase II duration.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Penefsky, Z. J. ; Buckley, N. M. ; Litwak, R. S.
    Springer
    Published 1972
    Staff View
    ISSN:
    1432-2013
    Keywords:
    Force-Frequency Relationship ; Temperature ; Human Myocardium ; Extracellular Calcium
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary The effects of temperature and calcium on force-frequency relationships in mammalian ventricular myocardium were studied in isolated papillary and ventricular muscle bundles. Tensions, velocities, and phase durations were determined from the isometric tension record and its first derivative. Decreasing bath temperature from 34–36°C to 27–31°C increased contractile tension and prolonged the phases of contraction in rat, guinea pig, and adult and fetal human tissues without altering the force-frequency relationship. Doubling extracellular [Ca++] beyond the 2.7 mM control for human tissue increased contractile tension and shortened phase I, and made the force-frequency relationship less steep or biphasic. These results suggest that the negative force-frequency relationship in the failing human heart cannot be explained merely on the basis on unavailability of Ca++ to the contractile proteins.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Staff View
    ISSN:
    1573-4986
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    1573-8221
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Summary A study was made of the effect produced by nucleosides (uridine, inosine and bases included into their composition—uracil and hypoxanthine) on the development of fatigue in the myocardium. The latter process was induced in acute experimental conditions by repeated overloading of the left cardiac ventricle by complete occlusion of the ascending aorta for 30 sec. The interval between the occlusions was 5 min. The maximal systolic pressure observed during aortic compression decreased with each subsequent compression, notwithstanding the unchanged or rising endodiastolic pressure. The dynamics of reduction of the maximal level of cardiac contractile function characterizes the process of fatigue. Administration of uridine, inosine and hypoxanthine following the fifth compression inhibits the further development of the fatigue process; the same effect is produced by strophanthin. Administration of a combination of uridine, uracil inosine, hypoxanthine and strophanthin eliminated the fatigue phenomena and increased the maximal level of the cardiac contractile function to a greater degree and for a longer time than separate administration of the same agents.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    1573-8221
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses