Search Results - (Author, Cooperation:N. Amariglio)
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1Latest Papers from Table of Contents or Articles in PressStem cells. m6A mRNA methylation facilitates resolution of naive pluripotency toward differentiationS. Geula ; S. Moshitch-Moshkovitz ; D. Dominissini ; A. A. Mansour ; N. Kol ; M. Salmon-Divon ; V. Hershkovitz ; E. Peer ; N. Mor ; Y. S. Manor ; M. S. Ben-Haim ; E. Eyal ; S. Yunger ; Y. Pinto ; D. A. Jaitin ; S. Viukov ; Y. Rais ; V. Krupalnik ; E. Chomsky ; M. Zerbib ; I. Maza ; Y. Rechavi ; R. Massarwa ; S. Hanna ; I. Amit ; E. Y. Levanon ; N. Amariglio ; N. Stern-Ginossar ; N. Novershtern ; G. Rechavi ; J. H. Hanna
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-01-09Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adenosine/*analogs & derivatives/metabolism ; Animals ; Blastocyst/enzymology ; Cell Differentiation/genetics/*physiology ; Cell Line ; Embryo Loss/genetics ; Epigenesis, Genetic ; Female ; Gene Knockout Techniques ; Male ; Methylation ; Methyltransferases/genetics/*physiology ; Mice ; Mice, Knockout ; Pluripotent Stem Cells/*cytology/enzymology ; RNA, Messenger/*metabolismPublished by: -
2Latest Papers from Table of Contents or Articles in PressD. Dominissini ; S. Nachtergaele ; S. Moshitch-Moshkovitz ; E. Peer ; N. Kol ; M. S. Ben-Haim ; Q. Dai ; A. Di Segni ; M. Salmon-Divon ; W. C. Clark ; G. Zheng ; T. Pan ; O. Solomon ; E. Eyal ; V. Hershkovitz ; D. Han ; L. C. Dore ; N. Amariglio ; G. Rechavi ; C. He
Nature Publishing Group (NPG)
Published 2016Staff ViewPublication Date: 2016-02-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressD. Dominissini ; S. Moshitch-Moshkovitz ; S. Schwartz ; M. Salmon-Divon ; L. Ungar ; S. Osenberg ; K. Cesarkas ; J. Jacob-Hirsch ; N. Amariglio ; M. Kupiec ; R. Sorek ; G. Rechavi
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-05-12Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adenosine/*analogs & derivatives/*genetics ; Alternative Splicing ; Animals ; Base Sequence ; Cell Line, Tumor ; Conserved Sequence ; Evolution, Molecular ; Hep G2 Cells ; Humans ; *Metabolome/genetics ; Methylation ; Methyltransferases/deficiency/genetics/metabolism ; Mice ; RNA/genetics/*metabolism ; RNA, Ribosomal/genetics/metabolism ; RNA, Transfer/genetics/metabolism ; RNA-Binding Proteins/metabolism ; Transcriptome/geneticsPublished by: -
4Articles: DFG German National LicensesCoscas, D. ; Chowers, M. ; Levite, M. ; Amariglio, N. ; Lang, A. ; Barshack, I. ; Bar-Meir, S. ; Chowers, Y.
Oxford, UK; Malden, USA : Blackwell Science Ltd
Published 2004Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: TCRDV1-positive lymphocytes, which infiltrate colon carcinomas, were recently shown to be cytolytic for tumour cells. However, the immune compartment from which these cells originate is unknown. The aim of the present studies was to determine the origin of TCRDV1-positive cells in colonic neoplasia. Biopsies were obtained from normal colon, polyps or carcinomas, concurrently with a sample from the peripheral blood. RNA was extracted and a TCRDV1-specific reverse transcriptase-polymerase chain reaction (RT-PCR) was performed. Amplification products were analysed by a CDR3 display and sequence analysis. In five out of six patients, the TCRDV1 CDR3 display of the whole cell population within the neoplastic tissue was distinct from that in the normal mucosa and the peripheral blood. The nucleotide sequences of CDR3 domains from the three compartments were distinct as well. In one patient, a pattern similar to the CDR3 display was detected in neoplastic and normal intestinal tissues. However, using junction-specific RT-PCR of CDR3 sequences derived from the neoplastic cells, such sequences could be detected in all three compartments. These findings suggest that in contrast to the current paradigm, a unique TCRDV1 cell population circulates in the peripheral blood and normal intestinal tissue and infiltrates colon neoplasia rather than being restricted to a single compartment as previously thought.Type of Medium: Electronic ResourceURL: