Search Results - (Author, Cooperation:M. Wood)

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  1. 1
    Doreen E. Culham, Irina A. Shkel, M. Thomas Record , Jr., Janet M. Wood
    American Chemical Society (ACS)
    Published 2018
    Staff View
    Publication Date:
    2018-08-10
    Publisher:
    American Chemical Society (ACS)
    Print ISSN:
    0006-2960
    Electronic ISSN:
    1520-4995
    Topics:
    Biology
    Chemistry and Pharmacology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2018-02-28
    Publisher:
    Wiley-Blackwell
    Print ISSN:
    0094-8276
    Electronic ISSN:
    1944-8007
    Topics:
    Geosciences
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2018-02-08
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    1098-0121
    Electronic ISSN:
    1095-3795
    Topics:
    Physics
    Keywords:
    Semiconductors II: surfaces, interfaces, microstructures, and related topics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
  5. 5
  6. 6
    Staff View
    Publication Date:
    2013-09-24
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    *Bacteria/enzymology/genetics/metabolism ; Bacterial Proteins/chemistry/genetics/metabolism ; Enzymes/*chemistry/*genetics/metabolism ; Gene Expression Profiling ; Genes, Bacterial/genetics ; Genome, Bacterial/*genetics ; Glycolysis ; Kinetics ; Metabolic Networks and Pathways/*genetics ; Metabolism ; Metabolomics ; Models, Molecular ; Molecular Sequence Annotation/*methods ; Multigene Family/genetics ; Operon ; *Structural Homology, Protein ; Substrate Specificity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    H. J. Pletsch ; L. Guillemot ; H. Fehrmann ; B. Allen ; M. Kramer ; C. Aulbert ; M. Ackermann ; M. Ajello ; A. de Angelis ; W. B. Atwood ; L. Baldini ; J. Ballet ; G. Barbiellini ; D. Bastieri ; K. Bechtol ; R. Bellazzini ; A. W. Borgland ; E. Bottacini ; T. J. Brandt ; J. Bregeon ; M. Brigida ; P. Bruel ; R. Buehler ; S. Buson ; G. A. Caliandro ; R. A. Cameron ; P. A. Caraveo ; J. M. Casandjian ; C. Cecchi ; O. Celik ; E. Charles ; R. C. Chaves ; C. C. Cheung ; J. Chiang ; S. Ciprini ; R. Claus ; J. Cohen-Tanugi ; J. Conrad ; S. Cutini ; F. D'Ammando ; C. D. Dermer ; S. W. Digel ; P. S. Drell ; A. Drlica-Wagner ; R. Dubois ; D. Dumora ; C. Favuzzi ; E. C. Ferrara ; A. Franckowiak ; Y. Fukazawa ; P. Fusco ; F. Gargano ; N. Gehrels ; S. Germani ; N. Giglietto ; F. Giordano ; M. Giroletti ; G. Godfrey ; I. A. Grenier ; M. H. Grondin ; J. E. Grove ; S. Guiriec ; D. Hadasch ; Y. Hanabata ; A. K. Harding ; P. R. den Hartog ; M. Hayashida ; E. Hays ; A. B. Hill ; X. Hou ; R. E. Hughes ; G. Johannesson ; M. S. Jackson ; T. Jogler ; A. S. Johnson ; W. N. Johnson ; J. Kataoka ; M. Kerr ; J. Knodlseder ; M. Kuss ; J. Lande ; S. Larsson ; L. Latronico ; M. Lemoine-Goumard ; F. Longo ; F. Loparco ; M. N. Lovellette ; P. Lubrano ; F. Massaro ; M. Mayer ; M. N. Mazziotta ; J. E. McEnery ; J. Mehault ; P. F. Michelson ; W. Mitthumsiri ; T. Mizuno ; M. E. Monzani ; A. Morselli ; I. V. Moskalenko ; S. Murgia ; T. Nakamori ; R. Nemmen ; E. Nuss ; M. Ohno ; T. Ohsugi ; N. Omodei ; M. Orienti ; E. Orlando ; F. de Palma ; D. Paneque ; J. S. Perkins ; F. Piron ; G. Pivato ; T. A. Porter ; S. Raino ; R. Rando ; P. S. Ray ; M. Razzano ; A. Reimer ; O. Reimer ; T. Reposeur ; S. Ritz ; R. W. Romani ; C. Romoli ; D. A. Sanchez ; P. M. Saz Parkinson ; A. Schulz ; C. Sgro ; E. do Couto e Silva ; E. J. Siskind ; D. A. Smith ; G. Spandre ; P. Spinelli ; D. J. Suson ; H. Takahashi ; T. Tanaka ; J. B. Thayer ; J. G. Thayer ; D. J. Thompson ; L. Tibaldo ; M. Tinivella ; E. Troja ; T. L. Usher ; J. Vandenbroucke ; V. Vasileiou ; G. Vianello ; V. Vitale ; A. P. Waite ; B. L. Winer ; K. S. Wood ; M. Wood ; Z. Yang ; S. Zimmer
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-11-01
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  8. 8
    M. Ackermann ; M. Ajello ; A. Allafort ; L. Baldini ; J. Ballet ; G. Barbiellini ; M. G. Baring ; D. Bastieri ; K. Bechtol ; R. Bellazzini ; R. D. Blandford ; E. D. Bloom ; E. Bonamente ; A. W. Borgland ; E. Bottacini ; T. J. Brandt ; J. Bregeon ; M. Brigida ; P. Bruel ; R. Buehler ; G. Busetto ; S. Buson ; G. A. Caliandro ; R. A. Cameron ; P. A. Caraveo ; J. M. Casandjian ; C. Cecchi ; O. Celik ; E. Charles ; S. Chaty ; R. C. Chaves ; A. Chekhtman ; C. C. Cheung ; J. Chiang ; G. Chiaro ; A. N. Cillis ; S. Ciprini ; R. Claus ; J. Cohen-Tanugi ; L. R. Cominsky ; J. Conrad ; S. Corbel ; S. Cutini ; F. D'Ammando ; A. de Angelis ; F. de Palma ; C. D. Dermer ; E. do Couto e Silva ; P. S. Drell ; A. Drlica-Wagner ; L. Falletti ; C. Favuzzi ; E. C. Ferrara ; A. Franckowiak ; Y. Fukazawa ; S. Funk ; P. Fusco ; F. Gargano ; S. Germani ; N. Giglietto ; P. Giommi ; F. Giordano ; M. Giroletti ; T. Glanzman ; G. Godfrey ; I. A. Grenier ; M. H. Grondin ; J. E. Grove ; S. Guiriec ; D. Hadasch ; Y. Hanabata ; A. K. Harding ; M. Hayashida ; K. Hayashi ; E. Hays ; J. W. Hewitt ; A. B. Hill ; R. E. Hughes ; M. S. Jackson ; T. Jogler ; G. Johannesson ; A. S. Johnson ; T. Kamae ; J. Kataoka ; J. Katsuta ; J. Knodlseder ; M. Kuss ; J. Lande ; S. Larsson ; L. Latronico ; M. Lemoine-Goumard ; F. Longo ; F. Loparco ; M. N. Lovellette ; P. Lubrano ; G. M. Madejski ; F. Massaro ; M. Mayer ; M. N. Mazziotta ; J. E. McEnery ; J. Mehault ; P. F. Michelson ; R. P. Mignani ; W. Mitthumsiri ; T. Mizuno ; A. A. Moiseev ; M. E. Monzani ; A. Morselli ; I. V. Moskalenko ; S. Murgia ; T. Nakamori ; R. Nemmen ; E. Nuss ; M. Ohno ; T. Ohsugi ; N. Omodei ; M. Orienti ; E. Orlando ; J. F. Ormes ; D. Paneque ; J. S. Perkins ; M. Pesce-Rollins ; F. Piron ; G. Pivato ; S. Raino ; R. Rando ; M. Razzano ; S. Razzaque ; A. Reimer ; O. Reimer ; S. Ritz ; C. Romoli ; M. Sanchez-Conde ; A. Schulz ; C. Sgro ; P. E. Simeon ; E. J. Siskind ; D. A. Smith ; G. Spandre ; P. Spinelli ; F. W. Stecker ; A. W. Strong ; D. J. Suson ; H. Tajima ; H. Takahashi ; T. Takahashi ; T. Tanaka ; J. G. Thayer ; J. B. Thayer ; D. J. Thompson ; S. E. Thorsett ; L. Tibaldo ; O. Tibolla ; M. Tinivella ; E. Troja ; Y. Uchiyama ; T. L. Usher ; J. Vandenbroucke ; V. Vasileiou ; G. Vianello ; V. Vitale ; A. P. Waite ; M. Werner ; B. L. Winer ; K. S. Wood ; M. Wood ; R. Yamazaki ; Z. Yang ; S. Zimmer
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-02-16
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  9. 9
    D. Sharp ; M. Wood-Schultz
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-02-01
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  10. 10
    L. A. T. C. Fermi ; M. Ackermann ; M. Ajello ; J. Ballet ; G. Barbiellini ; D. Bastieri ; A. Belfiore ; R. Bellazzini ; B. Berenji ; R. D. Blandford ; E. D. Bloom ; E. Bonamente ; A. W. Borgland ; J. Bregeon ; M. Brigida ; P. Bruel ; R. Buehler ; S. Buson ; G. A. Caliandro ; R. A. Cameron ; P. A. Caraveo ; E. Cavazzuti ; C. Cecchi ; O. Celik ; E. Charles ; S. Chaty ; A. Chekhtman ; C. C. Cheung ; J. Chiang ; S. Ciprini ; R. Claus ; J. Cohen-Tanugi ; S. Corbel ; R. H. Corbet ; S. Cutini ; A. de Luca ; P. R. den Hartog ; F. de Palma ; C. D. Dermer ; S. W. Digel ; E. do Couto e Silva ; D. Donato ; P. S. Drell ; A. Drlica-Wagner ; R. Dubois ; G. Dubus ; C. Favuzzi ; S. J. Fegan ; E. C. Ferrara ; W. B. Focke ; P. Fortin ; Y. Fukazawa ; S. Funk ; P. Fusco ; F. Gargano ; D. Gasparrini ; N. Gehrels ; S. Germani ; N. Giglietto ; F. Giordano ; M. Giroletti ; T. Glanzman ; G. Godfrey ; I. A. Grenier ; J. E. Grove ; S. Guiriec ; D. Hadasch ; Y. Hanabata ; A. K. Harding ; M. Hayashida ; E. Hays ; A. B. Hill ; R. E. Hughes ; G. Johannesson ; A. S. Johnson ; T. J. Johnson ; T. Kamae ; H. Katagiri ; J. Kataoka ; M. Kerr ; J. Knodlseder ; M. Kuss ; J. Lande ; F. Longo ; F. Loparco ; M. N. Lovellette ; P. Lubrano ; M. N. Mazziotta ; J. E. McEnery ; P. F. Michelson ; W. Mitthumsiri ; T. Mizuno ; C. Monte ; M. E. Monzani ; A. Morselli ; I. V. Moskalenko ; S. Murgia ; T. Nakamori ; M. Naumann-Godo ; J. P. Norris ; E. Nuss ; M. Ohno ; T. Ohsugi ; A. Okumura ; N. Omodei ; E. Orlando ; M. Ozaki ; D. Paneque ; D. Parent ; M. Pesce-Rollins ; M. Pierbattista ; F. Piron ; G. Pivato ; T. A. Porter ; S. Raino ; R. Rando ; M. Razzano ; A. Reimer ; O. Reimer ; S. Ritz ; R. W. Romani ; M. Roth ; P. M. Saz Parkinson ; C. Sgro ; E. J. Siskind ; G. Spandre ; P. Spinelli ; D. J. Suson ; H. Takahashi ; T. Tanaka ; J. G. Thayer ; J. B. Thayer ; D. J. Thompson ; L. Tibaldo ; M. Tinivella ; D. F. Torres ; G. Tosti ; E. Troja ; Y. Uchiyama ; T. L. Usher ; J. Vandenbroucke ; G. Vianello ; V. Vitale ; A. P. Waite ; B. L. Winer ; K. S. Wood ; M. Wood ; Z. Yang ; S. Zimmer ; M. J. Coe ; F. Di Mille ; P. G. Edwards ; M. D. Filipovic ; J. L. Payne ; J. Stevens ; M. A. Torres
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-01-17
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  11. 11
    M. Ackermann ; M. Ajello ; A. Allafort ; P. Schady ; L. Baldini ; J. Ballet ; G. Barbiellini ; D. Bastieri ; R. Bellazzini ; R. D. Blandford ; E. D. Bloom ; A. W. Borgland ; E. Bottacini ; A. Bouvier ; J. Bregeon ; M. Brigida ; P. Bruel ; R. Buehler ; S. Buson ; G. A. Caliandro ; R. A. Cameron ; P. A. Caraveo ; E. Cavazzuti ; C. Cecchi ; E. Charles ; R. C. Chaves ; A. Chekhtman ; C. C. Cheung ; J. Chiang ; G. Chiaro ; S. Ciprini ; R. Claus ; J. Cohen-Tanugi ; J. Conrad ; S. Cutini ; F. D'Ammando ; F. de Palma ; C. D. Dermer ; S. W. Digel ; E. do Couto e Silva ; A. Dominguez ; P. S. Drell ; A. Drlica-Wagner ; C. Favuzzi ; S. J. Fegan ; W. B. Focke ; A. Franckowiak ; Y. Fukazawa ; S. Funk ; P. Fusco ; F. Gargano ; D. Gasparrini ; N. Gehrels ; S. Germani ; N. Giglietto ; F. Giordano ; M. Giroletti ; T. Glanzman ; G. Godfrey ; I. A. Grenier ; J. E. Grove ; S. Guiriec ; M. Gustafsson ; D. Hadasch ; M. Hayashida ; E. Hays ; M. S. Jackson ; T. Jogler ; J. Kataoka ; J. Knodlseder ; M. Kuss ; J. Lande ; S. Larsson ; L. Latronico ; F. Longo ; F. Loparco ; M. N. Lovellette ; P. Lubrano ; M. N. Mazziotta ; J. E. McEnery ; J. Mehault ; P. F. Michelson ; T. Mizuno ; C. Monte ; M. E. Monzani ; A. Morselli ; I. V. Moskalenko ; S. Murgia ; A. Tramacere ; E. Nuss ; J. Greiner ; M. Ohno ; T. Ohsugi ; N. Omodei ; M. Orienti ; E. Orlando ; J. F. Ormes ; D. Paneque ; J. S. Perkins ; M. Pesce-Rollins ; F. Piron ; G. Pivato ; T. A. Porter ; S. Raino ; R. Rando ; M. Razzano ; S. Razzaque ; A. Reimer ; O. Reimer ; L. C. Reyes ; S. Ritz ; A. Rau ; C. Romoli ; M. Roth ; M. Sanchez-Conde ; D. A. Sanchez ; J. D. Scargle ; C. Sgro ; E. J. Siskind ; G. Spandre ; P. Spinelli ; L. Stawarz ; D. J. Suson ; H. Takahashi ; T. Tanaka ; J. G. Thayer ; D. J. Thompson ; L. Tibaldo ; M. Tinivella ; D. F. Torres ; G. Tosti ; E. Troja ; T. L. Usher ; J. Vandenbroucke ; V. Vasileiou ; G. Vianello ; V. Vitale ; A. P. Waite ; B. L. Winer ; K. S. Wood ; M. Wood
    American Association for the Advancement of Science (AAAS)
    Published 2012
    Staff View
    Publication Date:
    2012-11-03
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  12. 12
    Staff View
    Publication Date:
    2012-05-12
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  13. 13
    RO, S. L. ; BURN, M. WOOD ; SANDINE, W. E.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1979
    Staff View
    ISSN:
    1750-3841
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Process Engineering, Biotechnology, Nutrition Technology
    Notes:
    Inoculation of kimchi, a Korean style fermented Chinese cabbage, with Propionibacterium freudenreichii ss. shermanii (ATCC No. 13673) increased vitamin B12 production to a maximum of 102 ng/100g from 47 ng/100g in the control at 1 wk of fermentation at 4°C. Soy flour (0.5%) or beef extract (0.05%), added as protein sources to the inoculated kimchi, further increased the vitamin activity to 197 and 203 ng/100g, respectively, at 1 wk. The fresh, unfermented kimchi contained 16.8 mg of ascorbic acid per 100g and the vitamin decreased at a constant rate during the first 5 wk of fermentation.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  14. 14
    Wood, M. J. [Verfasser]

    Published 1985
    Staff View
    Type of Medium:
    article
    Publication Date:
    1985
    Keywords:
    Computer ; Analogschaltung ; Mikrocomputer ; Mikroelektronik ; Naturwissenschaften ; Elektronik ; Physik ; Schaltplan ; Schaltung
    In:
    Physics education, Bd. 20 (1985) H. 6, S. 305-309, 0031-9120
    Language:
    English
    Note:
    Literaturangaben
    FIS Bildung Literaturdatenbank
  15. 15
    Staff View
    Publication Date:
    2018-04-13
    Publisher:
    American Heart Association (AHA)
    Print ISSN:
    1942-325X
    Electronic ISSN:
    1942-3268
    Topics:
    Medicine
    Keywords:
    Genetics, Aneurysm, Vascular Disease
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  16. 16
    Postawa, Z. ; Maboudian, R. ; El-Maazawi, M. ; Ervin, M. H. ; Wood, M. C. ; Winograd, N.

    College Park, Md. : American Institute of Physics (AIP)
    Published 1992
    Staff View
    ISSN:
    1089-7690
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Chemistry and Pharmacology
    Notes:
    Multiphoton resonance ionization (MPRI) spectroscopy has been employed to investigate the ejection mechanisms of neutral and ionic particles from an ion-bombarded NaCl{100} single crystal. The results are used to reveal the similarities and the differences between ion bombardment and electron irradiation of alkali halides. The mass spectra of neutral species and positive and negative ions have been measured. The yield of Na+ ions is found to be two orders of magnitude higher than in measurements with electron bombardment. It is suggested that the secondary ions are created by direct emission from the collision cascade. The ejection of neutral Na atoms is observed to be very sensitive to the temperature of the target, the angle of incidence, and the state of the surface as determined by the time-of-flight (TOF) measurements. In particular, it is found that most of the neutral Na atoms are emitted with thermal energies, which indicates that desorption via electronic transitions dominates over ejections from collision cascades. The relative yield of the collisional component to the thermal component is found to vary significantly as the surface structure is modified. This investigation emphasizes the importance of measurements with low incident-ion dose which allows one to decouple the single ion/surface interaction from the accumulative effect of ion-induced surface modifications.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  17. 17
    Sarney, W. L. ; Wood, M. C.

    [S.l.] : American Institute of Physics (AIP)
    Published 2002
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    We find that the incorporation of Ge into SiC during the metalorganic chemical vapor deposition growth process improves the crystalline quality of SiC films grown on Si (111) substrates at 1000 °C. Secondary ion mass spectroscopy results indicate that Ge does not act as a surfactant, but rather it incorporates throughout the entire film. Transmission electron microscopy results show that high quality, single crystalline SiC films of up to 80 nm thickness are repeatably obtained for GeH4 flow rates ranging from 20 to 30 sccm. Higher GeH4 flow rates induce twinning and result in a reduced growth rate and increased surface roughness. Lower GeH4 flow rates result in polycrystalline and/or amorphous-like SiC films similar to what is normally obtained at such a low growth temperature. We discuss the role of Ge during growth and how its presence in the reactor during Si substrate carbonization results in higher quality SiC films than normally achieved for growth temperatures of 1000 °C.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  18. 18
    Cole, M. W. ; Joshi, P. C. ; Hubbard, C. W. ; Wood, M. C. ; Ervin, M. H. ; Geil, B.

    [S.l.] : American Institute of Physics (AIP)
    Published 2000
    Staff View
    ISSN:
    1089-7550
    Source:
    AIP Digital Archive
    Topics:
    Physics
    Notes:
    Ni/WSi/Ti/Pt Ohmic contacts to n-SiC were investigated as a function of annealing temperatures up to 1000 °C. Annealing at temperatures between 950 and 1000 °C yielded excellent Ohmic behavior. At these temperatures the contact–SiC interface was smooth, defect free, and characterized by a narrow Ni2Si reaction region. The annealed contacts possessed atomically smooth surface morphologies and exhibited minimal contact expansion. The residual carbon, resultant from SiC decompositon and reaction with Ni to form Ni2Si, was constrained by reaction with the WSi and Ti layers forming carbide phases of W and Ti spatially distant from the metal semiconductor interface. Our results demonstrate that the Ni/WSi/Ti/Pt composite Ohmic contact maintains the desirable electrical properties associated with Ni contacts and possesses excellent interfacial, compositional, and surface properties which are required for reliable high power and high temperature device operation. © 2000 American Institute of Physics.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  19. 19
    Wyllie, M. G. ; Wood, M. D. ; Moser, P. C.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1985
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: A method for the measurement of 3H-monoamine [noradrenaline (NA) and 5-hydroxytryptamine (5-HT)] uptake into intact brain following intracerebroventricular injection is described. Most of the accumulated monoamine was associated with nerve terminals (synaptosomes). Radioactivity in the synaptosomal fraction was retained by 0.45-μm filters and was osmotically sensitive, features indicative of accumulation within particles rather than binding to membranes. [3H]5-HT associated with synaptosomes was reduced in animals pretreated with the neurotoxin 5,7-dihydroxytryptamine, in parallel with a reduction in endogenous 5-HT levels. Oral administration of tricyclic antidepressants including clomipramine, desipramine, and imipramine inhibited the synaptosomal accumulation of 3H-monoamines. Overall, the features of the accumulation of 3H-monoamines, after intracerebroventricular administration, displayed many of the characteristics expected of a physiological monoamine reuptake system.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  20. 20
    Wood, M. S. ; Traynor, J. R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1989
    Staff View
    ISSN:
    1471-4159
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Abstract: The binding of the unselective opioid antagonist [3H]diprenorphine to homogenates prepared from rat brain and from guinea-pig brain and cerebellum has been studied in HEPES buffer containing 10 mM Mg2+ ions. Sequential displacement of bound [3H]diprenorphine by ligands with selectivity for μ-, 8- δ, and k-opioid receptors uncovers the multiple components of binding. In the presence of cold ligands that occupy all μ-, δ-, and k-sites, opioid binding still remains. This binding represents 20% of total specific sites and is displaced by naloxone. The nature of these undefined opioid binding sites is discussed.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses