Search Results - (Author, Cooperation:M. Vianna)
-
1F. Di Dario ; C. B. Alves ; H. Boos ; F. L. Fredou ; R. P. Lessa ; M. M. Mincarone ; M. A. Pinheiro ; C. N. Polaz ; R. E. Reis ; L. A. Rocha ; F. M. Santana ; R. A. Santos ; S. B. Santos ; M. Vianna ; F. Vieira
American Association for the Advancement of Science (AAAS)
Published 2015Staff ViewPublication Date: 2015-03-07Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Aquatic Organisms ; Brazil ; *Conservation of Natural Resources ; *Extinction, Biological ; *FisheriesPublished by: -
2Staff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] FROM time to time, reports have appeared of the low sensitivity of South American frogs to curare1, 2. These early experiments were made with crude curares, the reliability of which is always doubtful and in which apparent differences in potency may be due to differences ...Type of Medium: Electronic ResourceURL: -
3Izquierdo, L. A. ; Viola, H. ; Barros, D. M. ; Alonso, M. ; Vianna, M. R. M. ; Furman, M. ; Levi de Stein, M. ; Szapiro, G. ; Rodrigues, C. ; Choi, H. ; Medina, J. H. ; Izquierdo, I.
Oxford, UK : Blackwell Science Ltd
Published 2001Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Rats exposed to a novel environment just prior to or 1–2 h, but not 4 or 6 h, before retention testing exhibited an enhanced retrieval of a one-trial inhibitory avoidance training. The bilateral intrahippocampal infusion of PD098059, an inhibitor of mitogen-activated protein kinase (MAPK), the specific upstream activator of p42 and p44 MAPKs, given 10 min before the exposure to the novel environment, blocked the enhancing effect of novelty on memory retrieval. In addition, prenovelty infusion of dl-2-amino-5-phosphonovalerate (APV), an antagonist of glutamate NMDA receptors, produced similar effects. The exposure to the novel environment is associated with an activation of p42 and p44 MAPKs and an increase in the phosphorylation state of the transcription factor cAMP response element binding protein (CREB). No changes were observed in cAMP-dependent protein kinase (PKA) activity or in α-CAMKII activation. Taken together, our results indicate that novelty activates hippocampal MAPKs, which are necessary, along with glutamate NMDA receptors, for the enhancing effect of novelty on retrieval.Type of Medium: Electronic ResourceURL: