Search Results - (Author, Cooperation:M. Spannagl)
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1R. Brenchley ; M. Spannagl ; M. Pfeifer ; G. L. Barker ; R. D'Amore ; A. M. Allen ; N. McKenzie ; M. Kramer ; A. Kerhornou ; D. Bolser ; S. Kay ; D. Waite ; M. Trick ; I. Bancroft ; Y. Gu ; N. Huo ; M. C. Luo ; S. Sehgal ; B. Gill ; S. Kianian ; O. Anderson ; P. Kersey ; J. Dvorak ; W. R. McCombie ; A. Hall ; K. F. Mayer ; K. J. Edwards ; M. W. Bevan ; N. Hall
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-11-30Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Brachypodium/genetics ; *Bread ; Chromosomes, Plant/genetics ; Crops, Agricultural/genetics ; DNA, Complementary/genetics ; DNA, Plant/genetics ; Evolution, Molecular ; Genes, Plant/genetics ; Genome, Plant/*genetics ; Genomics ; Multigene Family/genetics ; Oryza/genetics ; Polymorphism, Single Nucleotide/genetics ; Polyploidy ; Pseudogenes/genetics ; Sequence Alignment ; Sequence Analysis, DNA ; Triticum/classification/*genetics ; Zea mays/geneticsPublished by: -
2T. Marcussen ; S. R. Sandve ; L. Heier ; M. Spannagl ; M. Pfeifer ; K. S. Jakobsen ; B. B. Wulff ; B. Steuernagel ; K. F. Mayer ; O. A. Olsen
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-07-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Bread ; *Evolution, Molecular ; Genes, Plant ; *Genome, Plant ; *Hybridization, Genetic ; Phylogeny ; Polyploidy ; Triticum/classification/*geneticsPublished by: -
3N. D. Young ; F. Debelle ; G. E. Oldroyd ; R. Geurts ; S. B. Cannon ; M. K. Udvardi ; V. A. Benedito ; K. F. Mayer ; J. Gouzy ; H. Schoof ; Y. Van de Peer ; S. Proost ; D. R. Cook ; B. C. Meyers ; M. Spannagl ; F. Cheung ; S. De Mita ; V. Krishnakumar ; H. Gundlach ; S. Zhou ; J. Mudge ; A. K. Bharti ; J. D. Murray ; M. A. Naoumkina ; B. Rosen ; K. A. Silverstein ; H. Tang ; S. Rombauts ; P. X. Zhao ; P. Zhou ; V. Barbe ; P. Bardou ; M. Bechner ; A. Bellec ; A. Berger ; H. Berges ; S. Bidwell ; T. Bisseling ; N. Choisne ; A. Couloux ; R. Denny ; S. Deshpande ; X. Dai ; J. J. Doyle ; A. M. Dudez ; A. D. Farmer ; S. Fouteau ; C. Franken ; C. Gibelin ; J. Gish ; S. Goldstein ; A. J. Gonzalez ; P. J. Green ; A. Hallab ; M. Hartog ; A. Hua ; S. J. Humphray ; D. H. Jeong ; Y. Jing ; A. Jocker ; S. M. Kenton ; D. J. Kim ; K. Klee ; H. Lai ; C. Lang ; S. Lin ; S. L. Macmil ; G. Magdelenat ; L. Matthews ; J. McCorrison ; E. L. Monaghan ; J. H. Mun ; F. Z. Najar ; C. Nicholson ; C. Noirot ; M. O'Bleness ; C. R. Paule ; J. Poulain ; F. Prion ; B. Qin ; C. Qu ; E. F. Retzel ; C. Riddle ; E. Sallet ; S. Samain ; N. Samson ; I. Sanders ; O. Saurat ; C. Scarpelli ; T. Schiex ; B. Segurens ; A. J. Severin ; D. J. Sherrier ; R. Shi ; S. Sims ; S. R. Singer ; S. Sinharoy ; L. Sterck ; A. Viollet ; B. B. Wang ; K. Wang ; M. Wang ; X. Wang ; J. Warfsmann ; J. Weissenbach ; D. D. White ; J. D. White ; G. B. Wiley ; P. Wincker ; Y. Xing ; L. Yang ; Z. Yao ; F. Ying ; J. Zhai ; L. Zhou ; A. Zuber ; J. Denarie ; R. A. Dixon ; G. D. May ; D. C. Schwartz ; J. Rogers ; F. Quetier ; C. D. Town ; B. A. Roe
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-11-18Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: *Biological Evolution ; *Genome, Plant ; Medicago truncatula/*genetics/*microbiology ; Molecular Sequence Data ; Nitrogen Fixation/genetics ; Rhizobium/*physiology ; Soybeans/genetics ; *Symbiosis ; Synteny ; Vitis/geneticsPublished by: -
4J. Jia ; S. Zhao ; X. Kong ; Y. Li ; G. Zhao ; W. He ; R. Appels ; M. Pfeifer ; Y. Tao ; X. Zhang ; R. Jing ; C. Zhang ; Y. Ma ; L. Gao ; C. Gao ; M. Spannagl ; K. F. Mayer ; D. Li ; S. Pan ; F. Zheng ; Q. Hu ; X. Xia ; J. Li ; Q. Liang ; J. Chen ; T. Wicker ; C. Gou ; H. Kuang ; G. He ; Y. Luo ; B. Keller ; Q. Xia ; P. Lu ; J. Wang ; H. Zou ; R. Zhang ; J. Xu ; J. Gao ; C. Middleton ; Z. Quan ; G. Liu ; H. Yang ; X. Liu ; Z. He ; L. Mao
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-03-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptation, Physiological/*genetics ; Brachypodium/genetics ; Chromosome Mapping ; Chromosomes, Plant/genetics ; DNA Transposable Elements/genetics ; Disease Resistance/genetics ; Genes, Plant/genetics ; Genome, Plant/*genetics ; Hordeum/genetics ; Molecular Sequence Data ; Plant Diseases ; Poaceae/*genetics ; Polyploidy ; Sequence Analysis, RNA ; Transcription Factors/genetics ; Triticum/*genetics/physiologyPublished by: -
5Staff View
Publication Date: 2018-08-17Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Botany, Ecology, Online OnlyPublished by: -
6WOLLENBERG, A. ; HÄNEL, S. ; SPANNAGL, M. ; SANDER, C. ; PLEWIG, G.
Oxford, UK : Blackwell Publishing Ltd
Published 1997Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Substantial subcutaneous haemorrhage without preceding trauma or underlying bleeding disorder is a rare occurrence in dermatological practice, essentially restricted to early childhood (acute haemorrhagic oedema of childhood). We report an adolescent with a morphologically unique bleeding manifestation. A 16-year-old presented with two episodes of massive subcutaneous haemorrhage in association with urticarial vasculitis. There was no history of preceding trauma or haemorrhagic disorder. Haemorrhage was observed in areas typically affected by angioedema, such as the periorbital, perioral, lingual, sublingual and laryngeal areas. History revealed an atopic diathesis with hay fever and examination showed alopecia areata. An antinuclear antibody titre and the presence of lupus anticoagulant indicated transient antiphospholipid antibodies. As urticaria corresponds to urticaria profunda angioedema, we hypothesize a pathophysiological relationship between superficial urticarial vasculitis and the deep variant of urticarial vasculitic disease, leading to the unique morphology present in our patient.Type of Medium: Electronic ResourceURL: -
7Landgraf-Leurs, M. M. C. ; Ladik, T. ; Smolka, B. ; Bock, T. ; Schramm, W. ; Spannagl, M. ; Landgraf, R.
Springer
Published 1987Staff ViewISSN: 1432-1440Keywords: Hemostasis ; Platelet aggregation ; Thromboxane ; DiabetesSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Coagulation parameters, platelet aggregation, and thromboxane production as well as metabolic parameters were measured in 31 diabetic patients, 12 without and 19 with clinically manifest late complications, and in 14 healthy control subjects. Spontaneous in vitro aggregation as well as ADP, collagen, and arachidonic acid induced aggregation were higher in both groups of diabetic patients, without an increase in thromboxane B2 production. In diabetic patients with late complications an increase in fibrinogen, fibrinogen cyanogen bromide peptide, factor VIII related antigen, C1-esterase inhibitor, and antithrombin III was observed in comparison to healthy subjects. Fibrinogen, C1-esterase inhibitor, and factor VIII related antigen were already elevated in diabetic patients without clinically manifest late vascular complications. No strict correlations were found between serum glucose, glycosylated hemoglobin, and glycosylated albumin, on the one hand, and coagulation promoting or inhibiting factors, aggregation or thromboxane B2 production, on the other, in either control or diabetic subjects. Also no correlations existed between the coagulation parameters and the aggregation results. In vitro incubation of pooled normal plasma with different glucose concentrations had no influence on the methods by which the coagulation parameters were measured. These data indicate that rather early in the diabetic state many changes take place in different phase of the thrombostatic process, all resulting in an increased hemostatic diathesis.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1432-1440Keywords: Hemodialysis ; Neutrophils ; Elastase ; Lactoferrin ; PentoxifyllineSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo. We investigated the effect of pentoxifylline on leukocyte and platelet counts and on plasma levels of extracellularly released neutrophil elastase and lactoferrin during a four-hour hemodialysis treatment. Eight patients received 400 mg of pentoxifylline or placebo orally twice a day over 14 days and an additional dose of 400 mg of pentoxifylline intravenously during hemodialysis. Each subject served as his own control in a randomized, double-blind, cross-over study. Combined oral and intravenous treatment with pentoxifylline prevented neither leukopenia nor neutrophil degranulation during the time interval studied. Elastase plasma levels paralleled the drop in leucocyte counts and thereafter increased similarly in both groups. Lactoferrin plasma levels exhibited less increase in the treated group; however, this effect was not statistically significant. This may be due to the small number of cases studied and to difficulties in reaching effective plasma levels without side effects.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1432-0584Keywords: Antiphospholipid antibodies ; Lupus anticoagulant ; End-stage renal disease ; Systemic lupus erythematosus ; ThrombosisSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary Antiphospholipid antibodies were found to be associated with certain clinical manifestations such as recurrent venous thrombosis or arterial occlusions in a wide spectrum of immune disorders [6]. We analyzed the plasma concentration of two isotypes (IgG, IgM) of anticardiolipin antibodies (ACA) and lupus anticoagulant (LAC) activity in 84 patients with end-stage renal disease. They were receiving different types of renal replacement therapy and had a high frequency of thrombotic vascular complications. The prevalence of positive tests and the mean ACA concentration obtained in the plasma of renal patients were compared with those in patients with systemic lupus erythematosus (SLE) and in healthy controls. When analyzed as a whole group, renal patients maintained on dialysis (n=45: hemodialysis,n=20; peritoneal dialysis) or with a functioning kidney transplant (n=19) did not differ in mean ACA concentration and LAC activity (n=84, ACA: IgG 10±7 U/ml, IgM 2±1 U/ml, LAC ratio: 1.0±0.2) from healthy subjects (n=50, ACA: IgG 10±3, IgM 2±1 U/ml, LAC ratio: 1.0±0.1) but they had a higher incidence of raised IgG-ACA titers (renal replacement 14% vs. normal controls 4%,p〈0.05). No significant correlation was found between thrombotic events and raised ACA or LAC activity in dialysis patients. In contrast, the proportion of SLE patients (n=51) with a raised concentration of ACA was significantly higher (IgG: 69%, IgM: 29%) than that among patients with renal replacement therapy (IgG: 14%, IgM: 4%) or normal controls (IgG: 4%, IgM: 2%,p〈0.002). Moreover, recurrent manifestations of thrombosis in SLE were associated with very high IgG-ACA (n=11, IgG 117±91 U/ml) and LAC activity (LAC ratio: 2.4±0.7) in comparison to SLE patients without thrombotic events (n=40, ACA: IgG 23±13). The results of our investigations demonstrate that the pathogenetic role of these phospholipid antibodies in end-stage renal disease is far from established.Type of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 1432-1289Source: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
11Griesmann, M., Chang, Y., Liu, X., Song, Y., Haberer, G., Crook, M. B., Billault-Penneteau, B., Lauressergues, D., Keller, J., Imanishi, L., Roswanjaya, Y. P., Kohlen, W., Pujic, P., Battenberg, K., Alloisio, N., Liang, Y., Hilhorst, H., Salgado, M. G., Hocher, V., Gherbi, H., Svistoonoff, S., Doyle, J. J., He, S., Xu, Y., Xu, S., Qu, J., Gao, Q., Fang, X., Fu, Y., Normand, P., Berry, A. M., Wall, L. G., Ane, J.-M., Pawlowski, K., Xu, X., Yang, H., Spannagl, M., Mayer, K. F. X., Wong, G. K.-S., Parniske, M., Delaux, P.-M., Cheng, S.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-07-13Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Botany, Online OnlyPublished by: -
12Juhasz, A., Belova, T., Florides, C. G., Maulis, C., Fischer, I., Gell, G., Birinyi, Z., Ong, J., Keeble-Gagnere, G., Maharajan, A., Ma, W., Gibson, P., Jia, J., Lang, D., Mayer, K. F. X., Spannagl, M., International Wheat Genome Sequencing Consortium, Tye-Din, J. A., Appels, R., Olsen, O.-A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-08-18Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
13Staff View
Publication Date: 2018-08-17Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Botany, Online OnlyPublished by: