Search Results - (Author, Cooperation:M. Simons)
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1Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-01-18Publisher: Wiley-BlackwellElectronic ISSN: 2045-7758Topics: BiologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2011-04-16Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
3Latest Papers from Table of Contents or Articles in PressY. Takeda ; S. Costa ; E. Delamarre ; C. Roncal ; R. Leite de Oliveira ; M. L. Squadrito ; V. Finisguerra ; S. Deschoemaeker ; F. Bruyere ; M. Wenes ; A. Hamm ; J. Serneels ; J. Magat ; T. Bhattacharyya ; A. Anisimov ; B. F. Jordan ; K. Alitalo ; P. Maxwell ; B. Gallez ; Z. W. Zhuang ; Y. Saito ; M. Simons ; M. De Palma ; M. Mazzone
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-10-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Animals ; Arteries/*growth & development ; Disease Models, Animal ; Extremities/*blood supply/pathology ; Female ; Heterozygote ; Homeostasis ; Hypoxia-Inducible Factor-Proline Dioxygenases ; Ischemia/pathology/*prevention & control ; Macrophages/*metabolism ; Male ; Mice ; Mice, 129 Strain ; Mice, Inbred BALB C ; Myocytes, Smooth Muscle/cytology ; NF-kappa B/metabolism ; Necrosis ; Phenotype ; Procollagen-Proline Dioxygenase/*deficiency/genetics/*metabolismPublished by: -
4Latest Papers from Table of Contents or Articles in PressM. Simons ; S. E. Minson ; A. Sladen ; F. Ortega ; J. Jiang ; S. E. Owen ; L. Meng ; J. P. Ampuero ; S. Wei ; R. Chu ; D. V. Helmberger ; H. Kanamori ; E. Hetland ; A. W. Moore ; F. H. Webb
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-05-21Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
5Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-02-10Publisher: Wiley-BlackwellPrint ISSN: 0094-8276Electronic ISSN: 1944-8007Topics: GeosciencesPhysicsPublished by: -
6Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2013-08-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Blood Circulation ; Cell Differentiation/genetics/physiology ; ELAV Proteins/genetics/physiology ; Endothelium, Vascular/cytology/physiology ; Homeodomain Proteins/genetics/metabolism ; Humans ; Lymphangiogenesis/genetics/*physiology ; Lymphatic Vessels/anatomy & histology/*embryology/physiology ; Lymphedema/physiopathology/*therapy ; Mice ; RNA Stability ; SOXF Transcription Factors/genetics/metabolism ; Tumor Suppressor Proteins/genetics/metabolism ; Vascular Endothelial Growth Factor A/genetics/metabolism ; Vascular Endothelial Growth Factor C/genetics/metabolism ; Vascular Endothelial Growth Factor Receptor-3/metabolism ; Veins/embryology/physiologyPublished by: -
7Latest Papers from Table of Contents or Articles in PressB. S. Ding ; Z. Cao ; R. Lis ; D. J. Nolan ; P. Guo ; M. Simons ; M. E. Penfold ; K. Shido ; S. Y. Rabbany ; S. Rafii
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-11-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acute Disease ; Animals ; Bile Ducts/surgery ; Carbon Tetrachloride ; Chemokine CXCL12/metabolism ; Chronic Disease ; Disease Models, Animal ; Drug-Induced Liver Injury, Chronic/metabolism/pathology ; Endothelial Cells/cytology/metabolism/pathology ; Ligation ; Liver Cirrhosis/*pathology ; Liver Regeneration/*physiology ; Mice ; Receptor, Fibroblast Growth Factor, Type 1/metabolism ; Receptors, CXCR/*metabolism ; Receptors, CXCR4/*metabolism ; *Signal TransductionPublished by: -
8Latest Papers from Table of Contents or Articles in PressZhang, F., Zarkada, G., Han, J., Li, J., Dubrac, A., Ola, R., Genet, G., Boye, K., Michon, P., Künzel, S. E., Camporez, J. P., Singh, A. K., Fong, G.-H., Simons, M., Tso, P., Fernandez-Hernando, C., Shulman, G. I., Sessa, W. C., Eichmann, A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-08-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Biology, Medicine, DiseasesPublished by: -
9Latest Papers from Table of Contents or Articles in PressCantuti-Castelvetri, L., Fitzner, D., Bosch-Queralt, M., Weil, M.-T., Su, M., Sen, P., Ruhwedel, T., Mitkovski, M., Trendelenburg, G., Lütjohann, D., Möbius, W., Simons, M.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-02-10Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Cell Biology, NeurosciencePublished by: -
10Latest Papers from Table of Contents or Articles in PressSchwartz, M. A., Vestweber, D., Simons, M.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-20Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyGeosciencesComputer ScienceMedicineNatural Sciences in GeneralPhysicsPublished by: -
11Articles: DFG German National LicensesSimons, M. ; Campisi, G. ; Hughes, H. L.
[S.l.] : American Institute of Physics (AIP)
Published 1991Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: Fast C-V measurement techniques are utilized to simultaneously probe both upper and lower interfaces of silicon-on-insulator/separation by implantation of oxygen buried oxide capacitors following exposure to pulsed ionizing irradiation. In addition to the relatively stable radiation-induced positive charge, reverse annealing is observed from both Si-SiO2 interfaces over the 200 μs to 300 s post exposure interval; this behavior is consistent with electron detrapping within the oxide. The dependence of electron detrapping on dc annealing bias is attributed to field-enhanced emission effects.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesSimons, M. ; Beinroth, S. ; Gleichmann, M. ; Liston, P. ; Korneluk, R. G. ; MacKenzie, A. E. ; Bähr, M. ; Klockgether, T. ; Robertson, G. S. ; Weller, M. ; Schulz, J. B.
Oxford UK : Blackwell Science Ltd.
Published 1999Staff ViewISSN: 1471-4159Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract : The inhibitor of apoptosis (IAP) family of anti-apoptoticgenes, originally discovered in baculovirus, exists in animals ranging frominsects to humans. Here, we investigated the ability of IAPs to suppress celldeath in both a neuronal model of apoptosis and excitotoxicity. Cerebellargranule neurons undergo apoptosis when switched from 25 to 5 mMpotassium, and excitotoxic cell death in response to glutamate. We examinedthe endogenous expression of four members of the IAP family, Xchromosome-linked IAP (XIAP), rat IAP1 (RIAP1), RIAP2, and neuronal apoptosisinhibitory protein (NAIP), by semiquantitative reverse PCR and immunoblotanalysis in cultured cerebellar granule neurons. Cerebellar granule neuronsexpress significant levels of RIAP2 mRNA and protein, but expression of RIAP1,NAIP, and XIAP was not detected. RIAP2 mRNA content and protein levels did notchange when cells were switched from 25 to 5 mM potassium. Todetermine whether ectopic expression of IAP influenced neuronal survival afterpotassium withdrawal or glutamate exposure, we used recombinant adenoviralvectors to target XIAP, human IAP1 (HIAP1), HIAP2, and NAIP into cerebellargranule neurons. We demonstrate that forced expression of IAPs efficientlyblocked potassium withdrawal-inducedN-acetly-Asp-Glu-Val-Asp-specific caspase activity and reduced DNAfragmentation. However, neurons were only protected from apoptosis up to 24 hafter potassium withdrawal, not at later time points suggesting that IAPSdelay but do not block apoptosis in cerebellar granule neurons. In contrast,treatment with 100 μM or 1 mM glutamate did not induce caspase activity and adenoviral-mediated expression of IAPs had no influence on subsequent excitotoxic cell death.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesNaughton, M. J. ; Limm, T. M. ; Ashdown, M. L. ; Simons, M. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1994Staff ViewISSN: 1744-313XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: DPB1 locus typing of the 155 cell 4AOHW panel was performed using a PCR-RFLP method. Ambiguity of allele assignment was resolved by amplification using sequence-specific primers. Of the 150 cells for which typings were achieved, three exhibited unusual restriction enzyme fragment patterns, suggesting the possibility of novel DPB1 alleles. Sequence analysis revealed one allele present in the currently reported 46, one novel allele (4AOHW/107) not present among the 46, and one from a non-human primate which is being investigated. Twenty-six (26) of the 34 10IHW cells have been studied previously by cDNA RFLP, and strong haplotypic associations have been demonstrated between DPA1 and DPB1 locus alleles. It is proposed that exploitation of intron polymorphisms marking haplotypes will be an integral part of future DPB 1 typing as a ‘first-pass’ stratification process to minimize the requirement for sequence-based methods to definitively assign DPB 1 alleles.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesPropert,, D. N. ; Bernad, C. C. A. ; Simons, M. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1982Staff ViewISSN: 1744-313XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineNotes: Immnoglobulin allotypes (Gm) were analysed in 40 multiple sclerois (MS) patients and the distribution of phenotypes compared to that in 1220 healthy controls. The frequencies of Gm(1) and Gm(1, 2) are significantly increased in the patietns suggesting that the presence of the Gm3;5,13,14 haplotype confers a resistance to the development of MS.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1747-6593Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Energy, Environment Protection, Nuclear Power EngineeringNotes: This paper describes the nature of the spoil from the tunnelling activities, the plant requirements for its handling, and the investigation into possible disposal locations carried out in 1986 with a view to minimizing environmental impact. It further describes some of the steps currently being taken to minimize environmental impact at Shakespeare Cliff.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] The role of phytohaemagglutinin (PHA) determinants and lymphocyte surface reactive sites has been investigated in the lymphocyte transformation phenomenon. Results suggest that the mitogenic moiety of the PHA molecule is closely related to or identical with the antigenic determinant sites, and that ...Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] THE lesions which develop on the chorioallantoic membrane (CAM) following the inoculation of adult fowl leucocytes represent the reaction of immunologically competent cells to histocompatibility antigens present in the membrane1. Using whole leucocyte preparations, Szenberg and Warner found that ...Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStanley, H.E. ; Buldyrev, S.V. ; Goldberger, A.L. ; Havlin, S. ; Peng, C.-K. ; Simons, M.
Amsterdam : ElsevierStaff ViewISSN: 0378-4371Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStanley, H.E. ; Buldyrev, S.V. ; Goldberger, A.L. ; Goldberger, Z.D. ; Havlin, S. ; Mantegna, R.N. ; Ossadnik, S.M. ; Peng, C.-K. ; Simons, M.
Amsterdam : ElsevierStaff ViewISSN: 0378-4371Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesPeng, C.-K. ; Buldyrev, S.V. ; Goldberger, A.L. ; Havlin, S. ; Sciortino, F. ; Simons, M. ; Stanley, H.E.
Amsterdam : ElsevierStaff ViewISSN: 0378-4371Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: