Search Results - (Author, Cooperation:M. Shoukry)
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1Latest Papers from Table of Contents or Articles in PressC. Attanasio ; A. S. Nord ; Y. Zhu ; M. J. Blow ; Z. Li ; D. K. Liberton ; H. Morrison ; I. Plajzer-Frick ; A. Holt ; R. Hosseini ; S. Phouanenavong ; J. A. Akiyama ; M. Shoukry ; V. Afzal ; E. M. Rubin ; D. R. FitzPatrick ; B. Ren ; B. Hallgrimsson ; L. A. Pennacchio ; A. Visel
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-10-26Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Craniofacial Abnormalities/genetics/pathology ; Enhancer Elements, Genetic/genetics/*physiology ; Epigenesis, Genetic ; Face/abnormalities/*anatomy & histology ; Gene Expression Profiling ; *Gene Expression Regulation, Developmental ; Gene Targeting ; Maxillofacial Development/*genetics ; Mice ; Mice, Transgenic ; Sequence Deletion ; Skull/abnormalities/anatomy & histology/*growth & developmentPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 0020-1693Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 0008-6215Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 1434-4475Keywords: Mixed-ligand complexes of palladium(II) ; Pd(II) complexes with propane 1,2,3-triamine ; Amino acids ; Peptides ; DNA ; Stability constants ; Potentiometric studiesSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Zusammenfassung Das Säure-Basen-Gleichgewicht von Propan-1,2,3-triamin (PTA) und die Bildungsgleichgewichte von binären und ternären Komplexen von Pd(II) mitPTA als Primärligand und Aminosäuren, Peptiden und DNA-Einheiten als Sekundärliganden wurden untersucht. Pd(II) bildet mitPTA einen 1:1-Komplex. Die ternären Komplexe werden stufenweise gebildet, wobeiPTA zuerst an Pd(II) koordiniert; dann erfolgt die Bindung an den Sekundärliganden. Die Hydrolyse des Pd-PTA-Komplexes und die Deprotonierung der Amide in den Peptidkomplexen werden im Zusammenhang mit physiologischen Bedingungen diskutiert.Notes: Summary The acid-base equilibria of propane 1,2,3-triamine (PTA) and the formation equilibria of binary and ternary complexes of palladium(II) withPTA as primary ligand and amino acid, peptide, and DNA subunits as secondary ligand have been investigated. Pd(II) is found to form a 1:1 complex withPTA. The ternary complexes are formed in a stepwise mechanism, wherebyPTA first binds to Pd(II) and then ligates to the secondary ligand. The hydrolysis of the Pd-PTA complex and the deprotonation of the amide residues in the peptide complexes are discussed in relation to physiological conditions.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1434-4475Keywords: Sulphamethoxazole ; Binary and ternary complexes ; Potentiometric studiesSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Zusammenfassung Die an den binären und ternären SystemenM(II)-sulpha undM(II)-phen-sulpha (M = Cu, Ni, Co, Zn;sulpha = Sulphamethoxazol;phen = Phenanthrolin) beteiligten Komplexbildungsgleichgewichte wurden bei 25°C und einer Ionenstärke von 0.1N NaNO3 mittels potentiometrischer Titration untersucht. Die Stabilitätskonstanten der binären und ternären Komplexe gehorchen der Reihenfolge vonIrving undWilliam. Die Bildung der ternären Komplexe wird auf der Basis der binären Spezies diskutiert. Die Art der Chelatbildung wurde durch Leitfähigkeitsmessungen ermittelt.Notes: Summary The complex formation equilibria involved in the binary and ternary systemsM(II)-sulpha andM(II)-phen-sulpha were investigated by potentiometric titrations at 25°C and a ionic strength of 0.1N NaNO3 (M = Cu, Ni, Co, Zn;sulpha = sulphamethoxazole;phen = phenanthroline). The stability constants of the binary and ternary complexes follow the order ofIrving andWilliam. The formation of the ternary complex is discussed in terms of the binary species. The mode of chelation was ascertained by conductivity measurements.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1434-4475Keywords: Cephradine complexes ; Equilibrium studies ; Synthesis of cephradine complexesSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyDescription / Table of Contents: Zusammenfassung Die Komplexbildungsgleichgewichte der binären und ternären SystemeM(II)-Cephradin undM(II)-2,2-Bipyridyl-Cephradin (M=Cu, Ni, Co und Zn) wurden bei 25°C und einer lonenstärke von 0.1M NaNO3 untersucht. Der Einfluß von Dioxan als Lösungsmittel auf die Protonierungskonstanten von Cephradin und die Komplexbildungskonstanten des Cu-Cephradin-Komplexes wurde ermittelt. Die relative Stabilität der ternären gegenüber den entsprechenden binären Komplexen wurde über ΔlogK verglichen. Die Bildungsweise der ternären Komplexe wurde mittels Leitfähigkeitsmessungen abgesichert. Die Cu(II)-, Ni(II)- und Co(II)-Komplexe von Cephradin wurden synthetisiert und durch Elementaranalyse, Leitfähigkeitsmessungen und Infrarotspektroskopie charakterisiert.Notes: Summary The complex formation equilibria of the binary and ternary systemsM(II)-Cephradine andM(II)-2,2-Bipyridyl-Cephradine were investigated by a potentiometric technique at 25°C and an ionic strength of 0.1M NaNO3 (M=Cu, Ni, Co, and Zn). The effect of dioxane as a solvent on the protonation constants of cephradine and the formation constants of the Cu-cephradine complex was studied. The relative stability of each ternary complex was compared with that of the corresponding binary complex in terms of ΔlogK. The mode of ternary complex formation was ascertained by conductivity measurements. The copper(II), nickel(II), and cobalt(II) complexes of cephradine were synthesized and characterized by elemental analysis, conductivity measurements, and IR spectra.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1433-3023Keywords: Imaging ; UrogynecologySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Radiologic evaluation is the mainstay in urogynecology. Currently videofluorourodynamics is the most precise diagnostic tool for evaluating disturbances of micturition. However, evolving application of ultrasonography, when combined with urodynamics, constitutes an attractive alternative for such evaluations. Magnetic resonance imaging (MRI) may prove to be a powerful research and clinical tool. Advantages and limitations of each imaging modality are discussed.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1432-5233Keywords: Non-insulin-dependent diabetes mellitus ; LDL ; DNA synthesis ; HIT cellsSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract The effect of lipoprotein-deficient serum (LPDS) with and without added low-density lipoprotein (LDL), isolated from diabetic subjects, on the replication of SV40-transformed islet cells (HIT cells) was investigated. Whole serum as well as LPDS preparations stimulated DNA synthesis maximally when added to the culture medium at a final concentration of 0.1%. The addition of LDL at 25 and 175 μg protein/ml medium did not cause further stimulation. On the contrary, the higher concentrations resulted in a significant inhibition. These results suggest that previously observed stimulation of DNA synthesis in smooth muscle cells by LDL from diabetic subjects is most likely due to the presence of growth factors in the serum of these patients and not to LDL per se.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1618-2650Keywords: Best. von Kobalt(II) mit Phenylazobenzaldoxim ; SpektralphotometrieSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: