Search Results - (Author, Cooperation:M. Shin)

2018-06-16

The American Association for Cancer Research (AACR)

1078-0432

1557-3265

Medicine

2018-02-13

American Chemical Society (ACS)

0002-7863

1520-5126

Chemistry and Pharmacology

2018-01-10

Wiley-Blackwell

Medicine

2015-05-21

Nature Publishing Group (NPG)

0028-0836

1476-4687

Biology

Chemistry and Pharmacology

Medicine

Natural Sciences in General

Physics

Animals ; Arteries/cytology ; *Cell Differentiation ; *Cell Lineage ; Embryonic Stem Cells/cytology/metabolism ; Endothelial Cells/*cytology/metabolism ; Humans ; *Lymphangiogenesis ; Lymphatic Vessels/*cytology/metabolism ; Multipotent Stem Cells/cytology/metabolism ; Stem Cell Niche ; Stem Cells/*cytology/metabolism ; Veins/*cytology ; Wnt Proteins/metabolism ; Zebrafish/embryology ; Zebrafish Proteins/metabolism

2018-09-27

The American Society for Pharmacology and Experimental Therapeutics (ASPET)

0026-895X

1521-0111

Chemistry and Pharmacology

Medicine

2018-10-12

American Society of Hematology (ASH)

0006-4971

1528-0020

Biology

Medicine

Transplantation, Myeloid Neoplasia, Clinical Trials and Observations

1089-7550

AIP Digital Archive

Physics

Shallow and deep centers were studied by means of temperature dependent Hall effect and photoluminescence (PL) measurements in two sets of undoped n-AlGaN samples grown by organometallic vapor phase epitaxy. The samples of these two series were grown under different conditions and had, as a result, electron concentrations differing by several orders of magnitude. The composition dependence of ionization energies of dominant donors in these two sets of samples is very different indicating that different types of centers are involved, but in both cases they are most probably related to some native defects. These defects behave as hydrogen-like donors for low Al compositions and become increasingly deeper with increasing Al content. The shallow-deep transition occurs at about x=0.2 in the low conductivity AlxGa1−xN series and at about x=0.5 for the high conductivity series. Several PL bands were detected in AlGaN and it is shown that the band at 3.05 eV is due to a radiative transition between deep donors in the upper part of the band gap and holes in the valence band or on shallow acceptors. For the yellow luminescence band at 2.25 eV it is demonstrated that this band consists of two overlapping bands and that the dominant band is due to a transition between the native donors and a carbon-related deep center. © 1996 American Institute of Physics.

Electronic Resource

1077-3118

AIP Digital Archive

Physics

Mach–Zehnder interferometry was used to measure the Pockels effect in a poled electro-optic polymer thin film with a coplanar electrode structure. The beam at the sample arm of the Mach–Zehnder interferometer passed through a polymer thin film which had been spin-coated on top of a clear gap between two electrodes patterned on an optical substrate. This unique optical geometry enabled the Pockels coefficients of the poled electro-optic polymer film in the directions of the ordinary and the extraordinary optic axes to be determined independently. As an example, the tensor ratio r33/r13 for a stilbene-dye-doped polyimide guest/host polymer film was determined experimentally; the ratio turned out to be 4.6, which was higher than the value of 3 predicted by the thermodynamic model. © 1996 American Institute of Physics.

Electronic Resource

1089-7550

AIP Digital Archive

Physics

Mach-Zehnder interferometry is employed to measure the Pockels coefficients in a poled thin polymer film, which serves as a reflection mirror in the sample arm of the interferometer. As a complete optical characterization of the electro-optic polymer film, the modulated light intensity of the Mach-Zehnder interferometer is investigated as a function of the optical bias in the reference arm, the modulation voltage applied to the film, the polarization angle of the incident light, and the angle of incidence on the film. The Mach-Zehnder interferometry measurement of the Pockels coefficients in the reflection configuration has an advantage over single-beam polarization interferometry in permitting the independent determination of the Pockels tensor components, r13 and r33. Particularly, in a reflection configuration two-beam interferometric measurement, a proper consideration of the optical path change due to the refractive angle change is found to be critical in determining the absolute values of the Pockels coefficients. © 1998 American Institute of Physics.

Electronic Resource

1077-3118

AIP Digital Archive

Physics

This letter reports that electromigration lifetimes of Al–2Cu (wt. %) thin-film conducting lines increase by more than three times when the lines are optimally aged to facilitate finely dispersed Al2Cu precipitates in the interior of the grains. In contrast to other studies which did not report a beneficial aging effect for Al–Cu films, the present work substantiates the fact that proper control of Al2Cu precipitates improves resistance to electromigration failure. However, the benefit of aging the Al-2Cu lines investigated here was less pronounced and confined to a more narrow heat-treatment "window" than that previously found for the Al–2Cu–1Si lines. © 1998 American Institute of Physics.

Electronic Resource

1749-6632

Blackwell Publishing Journal Backfiles 1879-2005

Natural Sciences in General

Electronic Resource

1749-6632

Blackwell Publishing Journal Backfiles 1879-2005

Natural Sciences in General

Electronic Resource

1089-7550

AIP Digital Archive

Physics

Layers of AlBN were grown on sapphire by organometallic vapor-phase epitaxy at 1050 °C using triethylboron, trimethylaluminum, and ammonia as precursors. It is shown that boron is readily incorporated into the layers and its concentration in the solid phase can be as high as 40%. However, single phase Al1−xBxN films can only be grown for compositions not exceeding x=0.01. For higher boron concentrations in the solid the second B-rich phase is formed. This phase was identified as wurtzite BN based on the results of transmission electron microscopy and x-ray diffraction. The growth of this thermodynamically unfavorable phase becomes possible, most probably, because it occurs within the framework provided by wurtzite AlN islands first formed on the surface and setting up the sites for lateral growth of wurtzite BN. That leads to formation of columnar structure of AlN and BN crystallites oriented in the basal plane and existing side by side. © 1997 American Institute of Physics.

Electronic Resource

1365-2222

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

To study the effect of azelastine on the immediate reaction to nasal allergen challenge, we performed a double blind, placebo-controlled cross-over clinical trial. Thirteen subjects with seasonal allergic rhinitis underwent nasal challenge with antigen 4 hr after a single oral 2 mg dose of azelastine. The response was monitored by counting the number of sneezes and by measuring the levels of histamine, prostaglandin D2, immunoreactive sulphidopeptide leukotrienes, kinins and TAME-esterase activity in recovered nasal lavages. After a single dose of azelastine, there was a significant reduction in sneezing (10 vs 2, P= 0.01) and in the median levels of recovered TAME-esterase activity (63.1 vs 17.5 c.p.m. × 10-3, P= 0.01), immunoreactive sulphidopeptide leukotrienes (7.5 vs 2.1 ng/ml, P= 0.03) and kinins (1370 vs 251 pg/ml, P= 0.03), with no significant reduction in the median levels of histamine (3.7 vs 1.2 ng/ml, P= 0.2) and prostaglandin D2 (70 vs 70 pg/ml, P= 0.2) compared to placebo (numbers represent total increase over diluent challenge). These results suggest that azelastine does not inhibit mast cell activation but affects the consequences of released histamine, namely sneezing, increased vascular permeability and the generation of kinins. The results further suggest that other cells, in addition to mast cells, might be responsible for the generation of leukotrienes during the early allergic response, and that azelastine reduces their ability to generate this mediator or that inhibition of leukotriene release from mast cells occurs at lower drug concentrations.

Electronic Resource

0003-2697

adsorbent ; butyl-Toyopearl 650 ; hydrophobic chromatography ; water-soluble proteins

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Electronic Resource

1439-0264

Blackwell Publishing Journal Backfiles 1879-2005

Medicine

Expression of calretinin in retina has been ascribed to multiple biological and functional aspects in the visual system. In this study, we examined the distribution patterns of calretinin immunoreactivity in gerbil and rat retina. In the gerbil, calretinin immunoreactivity was present in bipolar and amacrine cells of the inner nuclear layer and in neurones of the ganglion cell layer. In the rat, amacrine and ganglion cells showed calretinin immunoreactivity, but bipolar cells did not contain calretinin immunoreactivity. In both species, calretinin immunoreactivity was absent in cones, cone bipolars, and horizontal cells. In conclusion, gerbil as well as rat has a rod-dominant retina. The differences in calretinin expression between rat and gerbil require further investigations under various functional and developmental conditions.

Electronic Resource

0003-9861

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Physics

Electronic Resource

0003-9861

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Physics

Electronic Resource

0003-9861

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Physics

Electronic Resource

0003-9861

Elsevier Journal Backfiles on ScienceDirect 1907 - 2002

Biology

Chemistry and Pharmacology

Physics

Electronic Resource