Search Results - (Author, Cooperation:M. Schartl)

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  1. 1
    C. T. Amemiya ; J. Alfoldi ; A. P. Lee ; S. Fan ; H. Philippe ; I. Maccallum ; I. Braasch ; T. Manousaki ; I. Schneider ; N. Rohner ; C. Organ ; D. Chalopin ; J. J. Smith ; M. Robinson ; R. A. Dorrington ; M. Gerdol ; B. Aken ; M. A. Biscotti ; M. Barucca ; D. Baurain ; A. M. Berlin ; G. L. Blatch ; F. Buonocore ; T. Burmester ; M. S. Campbell ; A. Canapa ; J. P. Cannon ; A. Christoffels ; G. De Moro ; A. L. Edkins ; L. Fan ; A. M. Fausto ; N. Feiner ; M. Forconi ; J. Gamieldien ; S. Gnerre ; A. Gnirke ; J. V. Goldstone ; W. Haerty ; M. E. Hahn ; U. Hesse ; S. Hoffmann ; J. Johnson ; S. I. Karchner ; S. Kuraku ; M. Lara ; J. Z. Levin ; G. W. Litman ; E. Mauceli ; T. Miyake ; M. G. Mueller ; D. R. Nelson ; A. Nitsche ; E. Olmo ; T. Ota ; A. Pallavicini ; S. Panji ; B. Picone ; C. P. Ponting ; S. J. Prohaska ; D. Przybylski ; N. R. Saha ; V. Ravi ; F. J. Ribeiro ; T. Sauka-Spengler ; G. Scapigliati ; S. M. Searle ; T. Sharpe ; O. Simakov ; P. F. Stadler ; J. J. Stegeman ; K. Sumiyama ; D. Tabbaa ; H. Tafer ; J. Turner-Maier ; P. van Heusden ; S. White ; L. Williams ; M. Yandell ; H. Brinkmann ; J. N. Volff ; C. J. Tabin ; N. Shubin ; M. Schartl ; D. B. Jaffe ; J. H. Postlethwait ; B. Venkatesh ; F. Di Palma ; E. S. Lander ; A. Meyer ; K. Lindblad-Toh
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-04-20
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Animals, Genetically Modified ; *Biological Evolution ; Chick Embryo ; Conserved Sequence/genetics ; Enhancer Elements, Genetic/genetics ; Evolution, Molecular ; Extremities/anatomy & histology/growth & development ; Fishes/anatomy & histology/*classification/*genetics/physiology ; Genes, Homeobox/genetics ; Genome/*genetics ; Genomics ; Immunoglobulin M/genetics ; Mice ; Molecular Sequence Annotation ; Molecular Sequence Data ; Phylogeny ; Sequence Alignment ; Sequence Analysis, DNA ; Vertebrates/anatomy & histology/genetics/physiology
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Lamatsch, D. K. ; Schmid, M. ; Schartl, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 2002
    Staff View
    ISSN:
    1095-8649
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    Breeding experiments with the gynogenetic Amazon molly, Poecilia formosa, proved that mosaicism, detected by flow cytometry with the fluorescent dye DAPI was restricted to the soma, and that gynogenetic reproduction was maintained by the offspring. Potential pathways for how mosaicism might have arisen in P. formosa are discussed.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1095-8649.2002.tb02436.x

    Articles: DFG German National Licenses
  3. 3
    Schlupp, I. ; Parzefall, J. ; Epplen, J. T. ; Schartl, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1095-8649
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    DNA fingerprinting demonstrated no sexual reproduction of the gynogenetic Amazon molly Poecilia formosa with Limia vittata as host species, in contrast with a single report that claims to have found sexual reproduction with such matings.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1095-8649.1996.tb01472.x

    Articles: DFG German National Licenses
  4. 4
    Nanda, I. ; Schartl, M. ; Feichtinger, W. ; Schlupp, I. ; Parzefall, J. ; Schmid, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1095-8649
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    Cytogenetic analyses were performed on a triploid hybrid individual produced in the laboratory by mating Poecilia formosa, an all-female gynogenetic diploid species, with a normal male of melanistic ornamental Poecilia sphenops (black molly). Direct chromosome preparations revealed 69 (3n) chromosomes in the somatic complement. This cytogenetic observation in conjunction with the pigmentation phenotype leads us to conclude that occasional failure of sperm exclusion may result in the presence of triploid hybrids even in the natural habitats.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1095-8649.1995.tb01928.x

    Articles: DFG German National Licenses
  5. 5
    Coughlan, T. ; Schartl, M. ; Hornung, U. ; Hope, I. ; Stewart, A.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1999
    Staff View
    ISSN:
    1095-8649
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    A simple reliable PCR-based sex test for the platyfish Xiphophorus maculatus is described using sex chromosome-linked molecular markers. The test can distinguish sexes prior to dimorphic differentiation without killing the fish. The method also has potential in identification of male and female embryos prior to birth.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1095-8649.1999.tb00626.x

    Articles: DFG German National Licenses
  6. 6
    Hong, Y. ; Schartl, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0167-4781
    Keywords:
    (Fish) ; (Silver carp) ; Growth hormone gene ; PCR ; Recombinant DNA
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0167-4781(93)90199-N

    Articles: DFG German National Licenses
  7. 7
    Hong, Y. ; Schartl, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0378-1119
    Keywords:
    Recombinant DNA ; fish ; metallothionein gene ; polymerase chain reaction ; rainbow trout
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0378-1119(92)90105-X

    Articles: DFG German National Licenses
  8. 8
    Schartl, M. ; Barnekow, A.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0012-1606
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0012-1606(84)90298-7

    Articles: DFG German National Licenses
  9. 9
    Barnekow, A. ; Schartl, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0305-0491
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0305-0491(87)90371-3

    Articles: DFG German National Licenses
  10. 10
    Mauler, W. ; Eigenbrodt, E. ; Schartl, M. ; Anders, F.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0305-0491
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Chemistry and Pharmacology
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0305-0491(87)90331-2

    Articles: DFG German National Licenses
  11. 11
    Hong, Y. ; Winkler, C. ; Brem, G. ; Schartl, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0044-8486
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0044-8486(93)90039-2

    Articles: DFG German National Licenses
  12. 12
    Cavari, B. ; Funkenstein, B. ; Chen, T.T. ; Schartl, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0044-8486
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0044-8486(93)90070-F

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    0044-8486
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0044-8486(93)90036-X

    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    0165-4608
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0165-4608(91)90468-A

    Articles: DFG German National Licenses
  15. 15
    Schliewen, U. ; Fricke, H. ; Schartl, M. ; Epplen, J. T. ; Pääbo, S.

    [s.l.] : Nature Publishing Group
    Published 1993
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] SIR - In 1938, the first living coelacanth (Latimeria chalumnae) was trawled off the sandy estuary of the Chalumna River on the east coast of South Africa at a depth of 75 m. All 200 catches since then have come from the Comores, northwest of Madagascar. In August 1991, a gravid female was trawled ...
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1038/363405a0

    Articles: DFG German National Licenses
  16. 16
    Hong, Yunhan ; Winkler, Christoph ; Schartl, M.
    Springer
    Published 1998
    Staff View
    ISSN:
    1432-041X
    Keywords:
    Key words Chimera ; Donor-host compatibility ; Embryonic stem cell ; Medaka ; Pigmentation
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract  Embryonic stem (ES) cells from early vertebrate embryos only rarely retain their full developmental potential under in vitro culture conditions, but undergo differentiation and lose their ability for chimeric embryogenesis. This is reflected by the fact that the ES cell technology to date could only be fully developed in mice. In the fish Oryzias latipes, the medaka, one ES-like cell line, MES1, has been established which gives rise to a high frequency of somatic chimeras but a low degree of chimerism. Here we have tested the effect of donor genotype and cultivation time on the efficiency of cell culture derivation and on chimera formation. The HB12A, HB32C and HNI strains of medaka most efficiently and reproducibly give rise to blastula-derived cell cultures that produce pigmented chimeras in albino hosts. Seven chimeras grew to male or female adults with normal fertility, although none of them showed obvious donor germline contribution. During prolonged in vitro propagation the frequency of chimeras and the degree of chimerism dropped to a value retained in the long-term cultured MES1 cells. Obviously, genetic factors in host/donor compatibility and physiological changes during prolonged in vitro culture may compromise, but do not abolish, the developmental potential of medaka ES-like cells. Thus, elucidation of conditions that will expand the developmental potential of medaka blastula cell cultures should lead to a further improvement towards establishment of the ES cell technology in medaka.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004270050220

    Articles: DFG German National Licenses
  17. 17
    Staff View
    ISSN:
    1432-0886
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract. The platyfish (Xiphophorus maculatus), in which sex chromosomes are evident from stable and predictable inheritance of sex, is one of the best-studied lower vertebrates with respect to sex determination. In order to identify the structural equivalent for this in the karyotype, which does not contain heteromorphic pairs of chromosomes, two sex-linked molecular probes were used for fluorescent in situ hybridization analysis. One probe, derived from the melanoma oncogene locus ONC-Xmrk, stained both the X and the Y chromosome. This cytogenetic analysis mapped the sex-determining locus to the subtelomeric region of a medium-sized telocentric chromosome. Another probe, a repetitive element (XIR), specifically labeled the Y chromosome in metaphase spreads and in interphase nuclei. The sex chromosomes of X. maculatus can be considered to be at an early stage of evolution of gonosomes. Expansion of the XIR repeat is obviously one of the earliest of the molecular events that lead to divergence of the Y chromosome and recombinational isolation of the sex-determining locus.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004120050425

    Articles: DFG German National Licenses
  18. 18
    Staff View
    ISSN:
    1432-0886
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Medicine
    Notes:
    Abstract. Type I interferons (IFNs) are a family of proteins that are predominantly expressed in response to viral infection. Two serologically distinct forms of type I IFN, designated ChIFN1 and ChIFN2, have recently been recognized in the chicken. ChIFN1 is encoded by a cluster of ten or more intronless genes, whereas ChIFN2, whose primary sequence is 57% identical, is encoded by a single intronless gene. By fluorescence in situ hybridization we now demonstrate that the genes for ChIFN1 and ChIFN2 are all located on the short arm of the chicken Z chromosome. This assignment was confirmed by results that showed that DNA from male (ZZ) chickens yielded approximately twofold stronger Southern blot signals with ChIFN1 and ChIFN2 hybridization probes than DNA from females (ZW). Attempts to determine differences in IFN production between male and female chickens failed owing to a high degree of variation in virus-induced IFN expression between individuals of both sexes. Sex linkage of IFN genes was also observed in domestic ducks: fluorescence in situ hybridization of duck metaphase chromosomes with a duck type I IFN probe was confined to the terminal region of the long arm of the Z chromosome. Thus, in contrast to mammals, which have their IFN genes on autosomes, birds have the type I IFN genes on the sex chromosome.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/s004120050298

    Articles: DFG German National Licenses
  19. 19
    Hong, Y. ; Chen, S. ; Schartl, M.
    Springer
    Published 2000
    Staff View
    ISSN:
    1573-5168
    Keywords:
    chimera ; ES ; gene targeting ; medaka ; pluripotency
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract Totipotent embryonic stem (ES) cells represent a bridge that links in vitro and in vivo manipulations of animal genomes and have enormous potential for genetic engineering of livestock. We have recently established feeder cell-free conditions for culturing cells of midblastula embryos (MBE) of the medaka (Oryzias latipes) and obtained several stable cell lines that show all features of mouse ES cells in vitro. One of these lines, MES1, has been demonstrated to retain a diploid karyotype and can be induced to differentiate into various cell types in vitro. Upon microinjection into albino host blastulae, MES1 cells are able to form pigmented chimeras. Genotype-specific PCR analysis revealed that 90% of host blastulae transplanted with MES1 cells developed into chimeric fry. This high frequency was not compromised by cryostorage or DNA transfection of the donor cells. Transplantation of genetically labelled MES1 cells revealed a wide contribution to numerous organs derived from all three germ layers and differentiation into various types of functional cells. These ES properties of MES1 line was not abolished by stable gene transfer and long-term selection. Thus MES1 cells may represent a first promising cellular vehicle for the production of genetically modified fish. The genetic background has been found to have a profound effect on the efficacy of ES cell derivation and of chimera formation.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1023/A:1007871121784

    Articles: DFG German National Licenses