Search Results - (Author, Cooperation:M. Sakai)
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1Chikata, T., Tran, G. V., Murakoshi, H., Akahoshi, T., Qi, Y., Naranbhai, V., Kuse, N., Tamura, Y., Koyanagi, M., Sakai, S., Nguyen, D. H., Nguyen, D. T., Nguyen, H. T., Nguyen, T. V., Oka, S., Martin, M. P., Carrington, M., Sakai, K., Nguyen, K. V., Takiguchi, M.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-02-14Publisher: The American Society for Microbiology (ASM)Print ISSN: 0022-538XElectronic ISSN: 1098-5514Topics: MedicinePublished by: -
2Mohd Isa, I. L., Abbah, S. A., Kilcoyne, M., Sakai, D., Dockery, P., Finn, D. P., Pandit, A.
American Association for the Advancement of Science (AAAS)
Published 2018Staff ViewPublication Date: 2018-04-05Publisher: American Association for the Advancement of Science (AAAS)Electronic ISSN: 2375-2548Topics: Natural Sciences in GeneralPublished by: -
3A. R. Forrest ; H. Kawaji ; M. Rehli ; J. K. Baillie ; M. J. de Hoon ; V. Haberle ; T. Lassmann ; I. V. Kulakovskiy ; M. Lizio ; M. Itoh ; R. Andersson ; C. J. Mungall ; T. F. Meehan ; S. Schmeier ; N. Bertin ; M. Jorgensen ; E. Dimont ; E. Arner ; C. Schmidl ; U. Schaefer ; Y. A. Medvedeva ; C. Plessy ; M. Vitezic ; J. Severin ; C. Semple ; Y. Ishizu ; R. S. Young ; M. Francescatto ; I. Alam ; D. Albanese ; G. M. Altschuler ; T. Arakawa ; J. A. Archer ; P. Arner ; M. Babina ; S. Rennie ; P. J. Balwierz ; A. G. Beckhouse ; S. Pradhan-Bhatt ; J. A. Blake ; A. Blumenthal ; B. Bodega ; A. Bonetti ; J. Briggs ; F. Brombacher ; A. M. Burroughs ; A. Califano ; C. V. Cannistraci ; D. Carbajo ; Y. Chen ; M. Chierici ; Y. Ciani ; H. C. Clevers ; E. Dalla ; C. A. Davis ; M. Detmar ; A. D. Diehl ; T. Dohi ; F. Drablos ; A. S. Edge ; M. Edinger ; K. Ekwall ; M. Endoh ; H. Enomoto ; M. Fagiolini ; L. Fairbairn ; H. Fang ; M. C. Farach-Carson ; G. J. Faulkner ; A. V. Favorov ; M. E. Fisher ; M. C. Frith ; R. Fujita ; S. Fukuda ; C. Furlanello ; M. Furino ; J. Furusawa ; T. B. Geijtenbeek ; A. P. Gibson ; T. Gingeras ; D. Goldowitz ; J. Gough ; S. Guhl ; R. Guler ; S. Gustincich ; T. J. Ha ; M. Hamaguchi ; M. Hara ; M. Harbers ; J. Harshbarger ; A. Hasegawa ; Y. Hasegawa ; T. Hashimoto ; M. Herlyn ; K. J. Hitchens ; S. J. Ho Sui ; O. M. Hofmann ; I. Hoof ; F. Hori ; L. Huminiecki ; K. Iida ; T. Ikawa ; B. R. Jankovic ; H. Jia ; A. Joshi ; G. Jurman ; B. Kaczkowski ; C. Kai ; K. Kaida ; A. Kaiho ; K. Kajiyama ; M. Kanamori-Katayama ; A. S. Kasianov ; T. Kasukawa ; S. Katayama ; S. Kato ; S. Kawaguchi ; H. Kawamoto ; Y. I. Kawamura ; T. Kawashima ; J. S. Kempfle ; T. J. Kenna ; J. Kere ; L. M. Khachigian ; T. Kitamura ; S. P. Klinken ; A. J. Knox ; M. Kojima ; S. Kojima ; N. Kondo ; H. Koseki ; S. Koyasu ; S. Krampitz ; A. Kubosaki ; A. T. Kwon ; J. F. Laros ; W. Lee ; A. Lennartsson ; K. Li ; B. Lilje ; L. Lipovich ; A. Mackay-Sim ; R. Manabe ; J. C. Mar ; B. Marchand ; A. Mathelier ; N. Mejhert ; A. Meynert ; Y. Mizuno ; D. A. de Lima Morais ; H. Morikawa ; M. Morimoto ; K. Moro ; E. Motakis ; H. Motohashi ; C. L. Mummery ; M. Murata ; S. Nagao-Sato ; Y. Nakachi ; F. Nakahara ; T. Nakamura ; Y. Nakamura ; K. Nakazato ; E. van Nimwegen ; N. Ninomiya ; H. Nishiyori ; S. Noma ; T. Noazaki ; S. Ogishima ; N. Ohkura ; H. Ohimiya ; H. Ohno ; M. Ohshima ; M. Okada-Hatakeyama ; Y. Okazaki ; V. Orlando ; D. A. Ovchinnikov ; A. Pain ; R. Passier ; M. Patrikakis ; H. Persson ; S. Piazza ; J. G. Prendergast ; O. J. Rackham ; J. A. Ramilowski ; M. Rashid ; T. Ravasi ; P. Rizzu ; M. Roncador ; S. Roy ; M. B. Rye ; E. Saijyo ; A. Sajantila ; A. Saka ; S. Sakaguchi ; M. Sakai ; H. Sato ; S. Savvi ; A. Saxena ; C. Schneider ; E. A. Schultes ; G. G. Schulze-Tanzil ; A. Schwegmann ; T. Sengstag ; G. Sheng ; H. Shimoji ; Y. Shimoni ; J. W. Shin ; C. Simon ; D. Sugiyama ; T. Sugiyama ; M. Suzuki ; N. Suzuki ; R. K. Swoboda ; P. A. t Hoen ; M. Tagami ; N. Takahashi ; J. Takai ; H. Tanaka ; H. Tatsukawa ; Z. Tatum ; M. Thompson ; H. Toyodo ; T. Toyoda ; E. Valen ; M. van de Wetering ; L. M. van den Berg ; R. Verado ; D. Vijayan ; I. E. Vorontsov ; W. W. Wasserman ; S. Watanabe ; C. A. Wells ; L. N. Winteringham ; E. Wolvetang ; E. J. Wood ; Y. Yamaguchi ; M. Yamamoto ; M. Yoneda ; Y. Yonekura ; S. Yoshida ; S. E. Zabierowski ; P. G. Zhang ; X. Zhao ; S. Zucchelli ; K. M. Summers ; H. Suzuki ; C. O. Daub ; J. Kawai ; P. Heutink ; W. Hide ; T. C. Freeman ; B. Lenhard ; V. B. Bajic ; M. S. Taylor ; V. J. Makeev ; A. Sandelin ; D. A. Hume ; P. Carninci ; Y. Hayashizaki
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-03-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Atlases as Topic ; Cell Line ; Cells, Cultured ; Cluster Analysis ; Conserved Sequence/genetics ; Gene Expression Regulation/genetics ; Gene Regulatory Networks/genetics ; Genes, Essential/genetics ; Genome/genetics ; Humans ; Mice ; *Molecular Sequence Annotation ; Open Reading Frames/genetics ; Organ Specificity ; Promoter Regions, Genetic/*genetics ; RNA, Messenger/analysis/genetics ; Transcription Factors/metabolism ; Transcription Initiation Site ; Transcription, Genetic/genetics ; Transcriptome/*geneticsPublished by: -
4Ajiro, M., Sakai, H., Onogi, H., Yamamoto, M., Sumi, E., Sawada, T., Nomura, T., Kabashima, K., Hosoya, T., Hagiwara, M.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-09-15Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
5Staff View
Publication Date: 2012-06-29Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; *Biodiversity ; Commerce/*statistics & numerical data ; *Developing Countries ; Endangered Species/*statistics & numerical data ; Industry/*statistics & numerical data ; *InternationalityPublished by: -
6H. Masuda, H. Sakai, M. Tokunaga, M. Ochi, H. Takahashi, K. Akiba, A. Miyake, K. Kuroki, Y. Tokura, and S. Ishiwata
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-10-10Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Electronic structure and strongly correlated systemsPublished by: -
7Helena Bragança, Shiro Sakai, M. C. O. Aguiar, and Marcello Civelli
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-02-10Publisher: American Physical Society (APS)Print ISSN: 0031-9007Electronic ISSN: 1079-7114Topics: PhysicsKeywords: Condensed Matter: Electronic Properties, etc.Published by: -
8SIIIMIZU, Y. ; SAKAI, M. ; UMEMURA, Y. ; UEDA, H.
Oxford, UK : Blackwell Publishing Ltd
Published 1997Staff ViewISSN: 1365-2133Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Nitric oxide is generated from L-arginine by nitric oxide synthase (NOS), which has at least three isoJorms: endothelial-type NOS (eNOS) and brain-type NOS (bNOS) are constitutive enzymes, and inducible-type NOS (iNOS) is expressed after stimulation. Studies by the avidin-biotin immunocomplex method, revealed eNOS immunoreactivity exclusively in the human eccrine clear cells. No eNOS immunoreactivity was observed in the eccrine dark cells or myoepithelial cells. No staining of iNOS or bNOS was observed in the eccrine yland. These findings indicate that NO pUiys a physiological part in the production and/or excretion of sweat in the human skin eccritie gland.Type of Medium: Electronic ResourceURL: -
9Curry, J. J. ; Sakai, M. ; Lawler, J. E.
[S.l.] : American Institute of Physics (AIP)
Published 1998Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: We have used an x-ray absorption technique to measure the distribution of Hg atoms in a pure-Hg high-pressure arc lamp. The x rays are obtained from a molybdenum-anode x-ray tube at an accelerating potential of 25.3 kV. The spectral distribution of x rays which produce the absorption signal consists mainly of the Mo Kα and Kβ fluorescence peaks at 17.5 and 19.6 keV, respectively. Plane-wave illumination of the lamp and two-dimensional detection of the transmitted x rays allow us to probe the Hg atom density in all regions of the lamp, simultaneously, with a spatial resolution of 170 μm. A complete two-dimensional map of the density is obtained by Abel inversion of the absorption data. This map extends all the way out to the arc-envelope boundary and includes the cold regions of the discharge behind the electrodes. A temperature map of the discharge is obtained by combining the density information with an optical emission measurement of the core temperature at a single axial location. © 1998 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
10Arulkumaran, S. ; Sakai, M. ; Egawa, T. ; Ishikawa, H. ; Jimbo, T.
Woodbury, NY : American Institute of Physics (AIP)
Published 2002Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: High-electron-mobility transistors (HEMTs) have been demonstrated on both AlN/sapphire templates and sapphire substrates, and the dc characteristics of the fabricated devices were examined at room temperature. Better dc characteristics with high extrinsic transconductances and drain current densities were observed in the HEMTs grown on AlN/sapphire templates when compared with the HEMTs on sapphire substrates. Extrinsic transconductances of 214 and 137 mS/mm for Wg/Lg=15/2 μm HEMTs on AlN/sapphire templates and HEMTs on sapphire substrates were achieved, respectively. The enhancement of dc characteristics with small variations in threshold voltage (≤130 mV) is due to the reduction of dislocation density (1.5×108 cm−2). The decrease of dark spot density has been confirmed in the GaN grown on AlN/sapphire templates using cathodoluminescence measurements. The advantage of using AlN/sapphire templates is that low dislocation density GaN layers at a high temperature can be grown without using low-temperature-grown GaN buffer layers. © 2002 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
11FUJITA, Y. ; FUJITA, N. ; NAKAMURA, T. ; GOTO, T. ; FUJII, T. ; HIRAMORI, N. ; KIDA, T. ; SAKAI, M. ; NAKAGAKI, Y. ; IWASAKI, Y. ; NAKAGAWA, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1992Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: To clarify the significance of basic fetoprotein (BFP) in lymphocytes, we investigated whether BFP is produced in lymphocytes during blastic transformation. Peripheral blood lymphocytes obtained from 14 adults were cultured under the stimulation of lectins. The concentration of BFP in the culture medium (extracellular BFP) was estimated serially. The incorporation of [6-3 H] thymidine was assayed simultaneously. The intracellular BFP was measured by dual flow cytometry for DNA and BFP. A lymph node was studies immunohistochemically. Serum BFP was measured in four cases of lumphocytic leukaemia. In two cases, dual staining was performed. The intracellular BFP of the mitogen-stimulated lymphocytes was increased within 24 h. The extracellular BFP was increased exponentially from 72 h. The extracellular BFP at 96 h did not correlate with the [3H]-thymidine incorporation. The intracellular BFP increase began in G1 phase. Immunostaining showed that the B cells also produced BFP. Theserum BFP level in leukaemia was high in 1 of 4 cases and the leukaemic cells in two cases showed high intracellular BFP content. These observations indicate that BFP is produced in activated human lymphocytes and in lymphocytic leukaemic cells. The production of BFP during blastic transformation will be a useful new in vitro model for studying the biological role of BFP, and BFP labelling may offer some new possibilities for study of lymphocytes.Type of Medium: Electronic ResourceURL: -
12Takaoka, T. ; Terahara, M. ; Sakai, M. ; Kusunoki, I.
College Park, Md. : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: By collision with hyperthermal atoms, desorption of surface species can be induced. It is called collision induced desorption (CID). We studied a CID process of N2 adsorbed on a Ni(100) surface in an apparatus equipped with a molecular beam apparatus and an Fourier transform infrared spectrometer. The CID cross section was estimated, and the mechanism was discussed. © 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1365-2516Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. We encountered a 2-year-old boy with acquired haemophilia, which rarely occurs in children, who was complicated with nephrotic syndrome. In mid-August 2001, he was diagnosed to have nephrotic syndrome based on the presence of massive proteinuria and hypoalbuminaemia. Activated partial thromboplastin time (APTT) was normal at 42.4 s at that time. After starting prednisone administration of 2 mg kg−1 day−1, the proteinuria disappeared immediately. However, in early October the same year, subcutaneous ecchymosis and intramuscular bleeding occurred for no apparent reason, and from the examination results his APTT was 106.4 s, factor VIII (FVIII) activity was 〈1%, and the anti-FVIII inhibitor titre was 6.9 BU ml−1. As a result, he was diagnosed to have acquired haemophilia. The anti-nuclear antibody and anti-phospholipid antibody were negative. With recombinant activated FVII, haemostasis was obtained, and after administering three courses of steroid pulse therapy (methyl prednisolone: 20 mg kg−1 day−1 × 3 days), the anti-FVIII inhibitory activity disappeared. An analysis of the immunological and coagulation properties of his FVIII autoantibodies showed the anti-FVIII inhibitory activity to be mediated by IgG1 antibody. In other words, his FVIII inhibitor was a Th1 dominant and it provided a good response to treatment. These findings correlate with those of previous reports. The patient thereafter frequently demonstrated a recurrence of nephrotic syndrome. As a result, he is presently being managed with cyclosporine. However, no recurrence of the anti-FVIII titre has been observed.Type of Medium: Electronic ResourceURL: -
14Horigane, A.K. ; Engelaar, W.M.H.G. ; Toyoshima, H. ; Ono, H. ; Sakai, M. ; Okubo, A. ; Nagata, T.
Oxford, UK : Blackwell Publishing Ltd
Published 2000Staff ViewISSN: 1750-3841Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionProcess Engineering, Biotechnology, Nutrition TechnologyNotes: The presence of hollows in cooked rice grains found before in the cultivar Koshihikari was confirmed for 4 more cultivars with various amylose contents. The size, shape, and total volume of hollows differed between cultivars. Hollow volumes increased with grain volume and length before 100 °C was reached, but subsequently decreased during prolonged boiling. The previously proposed mechanism, describing sealing by gelatinized starch of cracks formed during soaking, seemed accurate for all 5 cultivars. Based on the hypothetical model of their formation, a relationship between amylose content and hollow formation was assumed. However, no correlation existed between final hollow volume and shape on 1 side and individual parameters such as flour gelatinization and amylose content on the other side.Type of Medium: Electronic ResourceURL: -
15Ueno, Y. ; Shi, J.-W. ; Yoshida, T. ; Kitao, T. ; Sakai, M. ; Chen, S.-N. ; Kou, G. H.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1439-0426Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyAgriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: A comparative study between EHVF (eel herpesvirus in Formosa) and HVA (Herpesvirus anguillae) was performed. Similar syncytia were produced by each virus in cell lines infected with the viruses and similar viral yields were obtained. Significant cross-reactivity was observed in neutralization tests between HVA and EHVF but HVA and EFVF were distinctly different from channel catfish virus (CCV). An electrophoretic analysis of the structural proteins of EHVF and HVA produced similar electrophoretic patterns. Western blotting analysis of the viral proteins, using antiserum against EHVF, supported the results obtained in the cross-neutralization test. In conclusion, the isolates of HVA and EHVF are tightly clustered.Type of Medium: Electronic ResourceURL: -
16Sakai, M. ; Savan, R. ; Kuragasaki, H. ; Aman, A.
Berlin, Germany : Blackwell Verlag GmbH
Published 2004Staff ViewISSN: 1439-0426Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyAgriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: The major histocompatibility complex (MHC) class II invariant chains are important for an efficient and complete presentation of antigens by MHC class II molecules. Invariant chain-like proteins (Iclp) 1 and 2 were identified by expressed sequence tag analysis from cDNA library of common carp head kidney (HK) stimulated with concanavalin A and lipopolysaccharide. The sequences were 1043 and 1016 bp in length encoding 234 and 198 amino acid proteins, respectively. Based on their predicted structure, the genes harboured transmembrane domain (TMD) and Tg (thyroglobulin) type 1 domains. Expression analysis revealed that both genes were expressed in normal tissues of HK, intestine, brain and gill. By database search, similar homologues were found in Atlantic salmon, fugu and catfish. Phylogenetic and alignment analysis indicate diversity among fish Iclps.Type of Medium: Electronic ResourceURL: -
17Staff View
ISSN: 1439-0426Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyAgriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionType of Medium: Electronic ResourceURL: -
18Sakai, M. ; Kamiya, H. ; Atsuta, S. ; Kobayashi, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1991Staff ViewISSN: 1439-0426Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyAgriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Rainbow trout, Oncorhynchus mykiss, injected with a water fraction extracted from abalone, Haliotis discus hannai, showed enhanced phagocytosis. This enhanced activity reached its maximum level 5 days after injection. The natural killer cell activities and the chemiluminescence responses of kidney leukocytes in fish treated with this fraction were also significantly increased, compared to those in albumin-treated fish. Rainbow trout injected intraperitoneally with this fraction showed an increased resistance to Vibrio anguillarum.〈section xml:id="abs1-2"〉〈title type="main"〉Zusammenfassung Immunomodulationseffekte bei Regenbogenforellen, Oncorhynchus mykiss, nach Injektion von Aba-lone-Entrakt, Haliotis discus hannaiBei Regenbogenforellen, Oncorynchus mykiss, denen ein wäßriger Extrakt der Abalone, Haliotis discus hannai, injiziert wurde, konnte eine gesteigerte Phagocytoseaktivität beobachtet werden. Diese Aktivi-tätssteigerung erreichte 5 Tage nach Verabreichung der Injektion ihr Maximum. Die natürliche Aktivi-tat von Killer-Zellen und die Chemoluminizenz-Reaktion der Nieren-Leukozyten in den mit dem Extrakt behandelten Fischen waren gegenüber Tieren, denen Albumin injiziert wurde, signifikant erhoht. Regenbogenforellen, denen der Abalone-Extrakt intraperitoneal injiziert wurde, zeigten eine erhohte Resistenz gegen Vibrio anguillarum.〈section xml:id="abs1-3"〉〈title type="main"〉Résumé Effects immunomodulatoires chez la truite arc-en-ciel, Onchorhynchus mykiss, traitie par des injections d'extraits d'onneaux, Haliotis discus hannai La truite arc-en-ciel, Onchorhynchus mykiss, traitie par injection d'une fraction aqueuse extraite d'ormeaux, Haliotis discus hannai, a montré une augmentation du taux de phagocytose. Cette augmentation de I'activité a atteint son niveau maximal cinq jours aprés injection. Les activitts naturelles des cellules tueuses et les résonses chimioluminescentes des leucocytes du rein des poissons traitis par cette fraction ont aussi significativement augmentis, par rapport ä celle des poissons traitis par de l'albumine. Les truites arc-en-ciel uaities par des injections intrapiritoniales de cette fraction ont montré une résistance accrue äVibrio anguillarum.Type of Medium: Electronic ResourceURL: -
19SAKAI, M. ; AMAAKI, N. ; ATSUTA, S. ; KOBAYASHI, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1987Staff ViewISSN: 1365-2761Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
20Yoshida, T. ; Inglis, V. ; Misawa, N. ; Kruger, R. ; Sakai, M.
Oxford BSL : Blackwell Science Ltd
Published 1997Staff ViewISSN: 1365-2761Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyMedicineType of Medium: Electronic ResourceURL: