Search Results - (Author, Cooperation:M. S. Cohen)
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1Latest Papers from Table of Contents or Articles in PressM. Pancera ; T. Zhou ; A. Druz ; I. S. Georgiev ; C. Soto ; J. Gorman ; J. Huang ; P. Acharya ; G. Y. Chuang ; G. Ofek ; G. B. Stewart-Jones ; J. Stuckey ; R. T. Bailer ; M. G. Joyce ; M. K. Louder ; N. Tumba ; Y. Yang ; B. Zhang ; M. S. Cohen ; B. F. Haynes ; J. R. Mascola ; L. Morris ; J. B. Munro ; S. C. Blanchard ; W. Mothes ; M. Connors ; P. D. Kwong
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-10-09Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: AIDS Vaccines/chemistry/immunology ; Amino Acid Sequence ; Antibodies, Neutralizing/immunology ; Cohort Studies ; Crystallography, X-Ray ; Genetic Variation ; Glycosylation ; HIV Antibodies/immunology ; HIV Envelope Protein gp120/*chemistry/genetics/*immunology ; HIV Envelope Protein gp41/*chemistry/genetics/*immunology ; HIV Infections/immunology ; Humans ; Immune Evasion ; Membrane Fusion ; Models, Molecular ; Molecular Sequence Data ; Polysaccharides/chemistry/immunology ; Protein Multimerization ; Protein Structure, Quaternary ; Protein Subunits/chemistry/genetics/immunology ; Structural Homology, Protein ; Virus InternalizationPublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2012-02-22Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: *Career Choice ; *SciencePublished by: -
3Latest Papers from Table of Contents or Articles in PressD. Colak ; N. Zaninovic ; M. S. Cohen ; Z. Rosenwaks ; W. Y. Yang ; J. Gerhardt ; M. D. Disney ; S. R. Jaffrey
American Association for the Advancement of Science (AAAS)
Published 2014Staff ViewPublication Date: 2014-03-01Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Line ; DNA Methylation ; Embryonic Stem Cells/metabolism ; Fragile X Mental Retardation Protein/*genetics ; Fragile X Syndrome/*genetics ; *Gene Silencing ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neurons/metabolism ; Nuclear Proteins/genetics ; Promoter Regions, Genetic/genetics ; RNA, Messenger/*genetics ; RNA, Small Interfering/genetics ; Trinucleotide Repeats/*geneticsPublished by: -
4Articles: DFG German National LicensesStaff View
ISSN: 1432-1106Keywords: Pudendal nerve ; Lordosis ; Cutaneous reflex ; Axial muscleSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Summary In 39 Urethane-anesthetized rats we have recorded the afferent volley in the dorsal roots and the electrical activity of the lateral longissimus muscle and its motor nerves during electrical stimulation of a cutaneous branch of the pudendal nerve. Male and female rats were used; the females were ovariectomized and either pretreated with estradiol or left without hormonal treatment. Conduction velocities in the pudendal nerve were 54 m/s for the largest Abeta fibers and averaged 10 m/s for A-delta fibers. Excitation of pudendal nerve afferents strongly potentiated the firing of axial motoneurons, at stimulus currents below threshold for A-delta fibers. Trains of three shocks to the pudendal nerve were considerably more effective than double or single shock trains. Repetition rates as low as 1/s had a long lasting excitatory effect on the lateral longissimus muscle and the magnitude of the responses increased gradually for several seconds with continued stimulation. Recordings from the axons of the epaxial motoneurons of female rats showed a strong activation of neuronal firing with an onset latency of 5.8 ms from the last shock of a three ms, three shock train; the onset in male rats, 8.4 ms, differed significantly. Peak spike activity occurred at mean latencies of 11, 22 and 102 ms in both sexes. A period of depressed firing was usually present from 34 to 50 ms. Males differed in having a larger peak in activity at 102 ms, but the overall profile of the responses was similar in males and females. No differences were seen in the overall response patterns of the estrogen-treated and untreated females. Responses of comparable magnitude were seen with ipsilateral or contralateral pudendal nerve stimulation; these were facilitated by bilateral stimulation. In electromyographic recordings, the onset of unit firings was seen at 6.4 ms latency in response to pudendal nerve stimulation. This unit activity was consistent with the firing pattern seen in the muscle nerves.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1432-2161Keywords: Radial head fracture ; Forearm fracture ; Radioulnar dislocationSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract We describe two patients with an Essex-Lopresti fracture dislocation in association with a dislocation of the elbow. This combination of injuries has not been previously reported. The Essex-Lopresti fracture is a rare injury, and the associated distal radioulnar dislocation is often missed. Meticulous radiographic evaluation of the wrist, including dynamic stress radiographs of the forearm, can lead to an earlier diagnosis and improved care of these patients.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesFalk, John Carl ; Narducy, K. W. ; Cohen, M. S. ; Brunner, R.
Stamford, Conn. [u.a.] : Wiley-Blackwell
Published 1980Staff ViewISSN: 0032-3888Keywords: Chemistry ; Chemical EngineeringSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyMechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsNotes: Notch width sensitivity, a serious deficiency of polycarbonate, can be improved by addition of 3-10 percent of specially modified methacrylate-butadiene-styrene (MBS) graft polymers. Blends of these modifiers with polycarbonate are transparent, in contrast to polycarbonate blends with previously reported notch width sensitivity improvers which are opaque. The synthesis of these modifiers is described together with physical properties of polycarbonate/modifier blends.Additional Material: 4 Ill.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0449-296XKeywords: Physics ; Polymer and Materials ScienceSource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyNotes: Carboranes attached to silicon through straight-chain alkyl groups were prepared and characterized for thermal stability by TGA and molecular weight change on heating. The monomers for these polymers were prepared generally by platinum-catalyzed addition of a silylhydride to an alkenyl or dialkenyl carborane. Polymerization was effected by hydrolysis-condensation of chlorosilanes, ring opening of cyclosiloxanes, and condensation of alkoxy and chlorosilanes. Two types of polymer structures were prepared, one contained m-carborane in the chain backbone, the other contained o-carborane as pendant alkylcarborane groups. Both types were obtained as elastomers; however, higher proportions of carborane in the polymers reduced elasticity and finally resulted in nonelastomers. TGA of the backbone carborane siloxane polymer indicated degradation at 370°C. in nitrogen and at 235°C. in air. Chain scission, as determined by molecular weight decrease, was observed on heating in nitrogen at 350°C. TGA of the pendant carborane siloxane polymer indicated that degradation in nitrogen and in air occurred at greater than 400°C. However, chain scission, as determined by molecular weight decrease, was observed upon heating at 300°C. in nitrogen.Additional Material: 4 Ill.Type of Medium: Electronic ResourceURL: