Search Results - (Author, Cooperation:M. S. Bartolomei)

Showing 1 - 7 results of 7, query time: 0.14s Refine Results
  1. 1
    Staff View
    Publication Date:
    2015-07-16
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2015-05-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; *Disease Progression ; Female ; Male ; Methyl-CpG-Binding Protein 2/*metabolism ; Microglia/*cytology/*physiology ; Rett Syndrome/*pathology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    M. Susiarjo ; M. S. Bartolomei
    American Association for the Advancement of Science (AAAS)
    Published 2014
    Staff View
    Publication Date:
    2014-08-16
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; *DNA Methylation ; Female ; Fetal Nutrition Disorders/*metabolism ; Male ; Pregnancy ; *Prenatal Exposure Delayed Effects ; Spermatozoa/*metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2013-07-19
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Adult Stem Cells/*cytology/*physiology ; Animals ; Epigenesis, Genetic/genetics ; Gene Expression Regulation, Developmental ; *Genomic Imprinting ; Insulin-Like Growth Factor II/*genetics/*metabolism ; Mice ; RNA, Long Noncoding/*genetics/*metabolism ; Receptor, IGF Type 1/genetics ; Signal Transduction ; Transcriptional Activation
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    R. N. Plasschaert ; M. S. Bartolomei
    Nature Publishing Group (NPG)
    Published 2013
    Staff View
    Publication Date:
    2013-09-03
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Autistic Disorder/*genetics ; DNA Topoisomerases, Type I/*metabolism ; Humans ; *Transcription Elongation, Genetic
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  6. 6
    San; Miguel, J. M., Abramowitz, L. K., Bartolomei, M. S.
    The Company of Biologists
    Published 2018
    Staff View
    Publication Date:
    2018-04-14
    Publisher:
    The Company of Biologists
    Print ISSN:
    0950-1991
    Electronic ISSN:
    1477-9129
    Topics:
    Biology
    Keywords:
    Chromatin & epigenetics, Reproductive biology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  7. 7
    Staff View
    ISSN:
    1432-041X
    Keywords:
    Key words Imprinting ; Repetitive elements ; H19 ; Transgenes ; DNA methylation
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract  The molecular mechanism leading to the imprinted expression of genes is poorly understood. While no conserved cis-acting elements have been identified within the known loci, many imprinted genes are located near directly repetitive sequence elements, suggesting that such repeats might play a role in imprinted gene expression. The maternally expressed mouse H19 gene is located approximately 1.5 kb downstream from a 461-bp G-rich repetitive element. We have used a transgenic model to investigate whether this element is essential for H19 imprinting. Previous results demonstrated that a transgene, which contains 14 kb of H19 sequence, exhibits parent-of-origin specific expression and methylation analogous to the endogenous H19 imprinting pattern. Here, we have generated transgenes lacking the G-rich repeat. One transgene, containing a deletion of the G-rich repetitive element but which includes an additional 1.7 kb of 5’H19 sequence, is imprinted similarly to the endogenous H19 gene. To determine whether the G-rich repeat is conserved in other imprinted mammalian H19 homologues, additional 5’ flanking sequences were cloned from the rat and human. This element is conserved in the rat but not in human DNA. These results suggest that the 461-bp G-rich repetitive element is not essential for H19 imprinting.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses