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1Latest Papers from Table of Contents or Articles in PressS. Djebali ; C. A. Davis ; A. Merkel ; A. Dobin ; T. Lassmann ; A. Mortazavi ; A. Tanzer ; J. Lagarde ; W. Lin ; F. Schlesinger ; C. Xue ; G. K. Marinov ; J. Khatun ; B. A. Williams ; C. Zaleski ; J. Rozowsky ; M. Roder ; F. Kokocinski ; R. F. Abdelhamid ; T. Alioto ; I. Antoshechkin ; M. T. Baer ; N. S. Bar ; P. Batut ; K. Bell ; I. Bell ; S. Chakrabortty ; X. Chen ; J. Chrast ; J. Curado ; T. Derrien ; J. Drenkow ; E. Dumais ; J. Dumais ; R. Duttagupta ; E. Falconnet ; M. Fastuca ; K. Fejes-Toth ; P. Ferreira ; S. Foissac ; M. J. Fullwood ; H. Gao ; D. Gonzalez ; A. Gordon ; H. Gunawardena ; C. Howald ; S. Jha ; R. Johnson ; P. Kapranov ; B. King ; C. Kingswood ; O. J. Luo ; E. Park ; K. Persaud ; J. B. Preall ; P. Ribeca ; B. Risk ; D. Robyr ; M. Sammeth ; L. Schaffer ; L. H. See ; A. Shahab ; J. Skancke ; A. M. Suzuki ; H. Takahashi ; H. Tilgner ; D. Trout ; N. Walters ; H. Wang ; J. Wrobel ; Y. Yu ; X. Ruan ; Y. Hayashizaki ; J. Harrow ; M. Gerstein ; T. Hubbard ; A. Reymond ; S. E. Antonarakis ; G. Hannon ; M. C. Giddings ; Y. Ruan ; B. Wold ; P. Carninci ; R. Guigo ; T. R. Gingeras
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-09-08Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alleles ; Cell Line ; DNA/*genetics ; DNA, Intergenic/genetics ; *Encyclopedias as Topic ; Enhancer Elements, Genetic ; Exons/genetics ; Gene Expression Profiling ; Genes/genetics ; Genome, Human/*genetics ; Genomics ; Humans ; *Molecular Sequence Annotation ; Polyadenylation/genetics ; Protein Isoforms/genetics ; RNA/biosynthesis/genetics ; RNA Editing/genetics ; RNA Splicing/genetics ; Regulatory Sequences, Nucleic Acid/*genetics ; Repetitive Sequences, Nucleic Acid/genetics ; Sequence Analysis, RNA ; Transcription, Genetic/*genetics ; Transcriptome/*geneticsPublished by: -
2Articles: DFG German National LicensesStaff View
ISSN: 1359-0197Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
3Articles: DFG German National LicensesStaff View
ISSN: 1359-0197Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesSurface layer structure analysis of stainless steel tubing used in LWR primary circuit-an ESCA studyStaff View
ISSN: 0042-207XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 1432-5233Keywords: C-peptide ; Diabetes mellitus ; Glucose clamp ; Insulin ; ProinsulinSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Elevated fasting proinsulin immunoreactive material (PIM) has previously been found in patients with type 2 (non-insulin-dependent) diabetes mellitus. It is not known whether this is a genetic trait or whether it is related to the manifestation of type 2 diabetes. Neither is it clear whether the raised fasting insulin immunoreactivity previously observed in first-degree relatives of patients with type 2 diabetes is due to raised PIM. Furthermore, it has not been investigated whether first-degree relatives have altered PIM responses to different secretagogoues. To study this, PIM, insulin and C-peptide were measured in patients with type 2 diabetes, in their first-degree relatives and in healthy control subjects in the fasting state and in relatives and controls during a hyperglycemic clamp. At the end of the hyperglycemic clamp, 0.5 mg of glucagon was given intravenously to stress the beta cells further. Fasting PIM concentrations were significantly higher in patients with type 2 diabetes (P〈0.05). These patients did not have significantly elevated fasting insulin levels when corrected for PIM. In the relatives, fasting insulin concentrations were elevated but PIM levels were normal suggesting that the increase in fasting insulin concentrations reflected an increase in true insulin. The incremental PIM, insulin and C-peptide responses to glucose and glucagon in the relatives were not different from those in the controls. We conclude that elevated fasting PIM levels in patients with type 2 diabetes seem not to be a genetic trait. First-degree relatives of patients with type 2 diabetes are truly hyperinsulinemic in the fasting state, and they have proportional PIM, insulin and C-peptide responses to glucose and glucagon.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1573-8205Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringPhysicsType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1588-2780Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringNotes: Abstract The γ- and α-radiolysis of cyclopentane were compared in the presence and absence of iodine scavenger. The G-values of the main hydrocarbon products, cyclopentene and bicyclopentyl are 2.22 and 0.56 molecule/100 eV in α-radiolysis and 3.25 and 1.23, respectively, in α-radiolysis. During high LET α-irradiation the yields of products formed by a radical mechanism are much smaller (G=1.18) than in γ-radiolysis (G=2.68), whereas “unimolecular” cyclopentene formation is hardly influenced by LET (G=1.8 and 1.6, respectively).Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 1588-2780Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringNotes: Abstract The γ- and α-radiolysis of cyclohexane, cycloheptane and cyclooctane was investigated in the absence and presence of iodine scavenger. Comparison of the distributions of products formed revealed considerable differences between γ- and α-radiolysis, and the decomposition of strainless cyclohexane and strained cycloheptane and cyclooctane.Type of Medium: Electronic ResourceURL: