Search Results - (Author, Cooperation:M. Q. Zhang)
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1Latest Papers from Table of Contents or Articles in PressD. Leung ; I. Jung ; N. Rajagopal ; A. Schmitt ; S. Selvaraj ; A. Y. Lee ; C. A. Yen ; S. Lin ; Y. Lin ; Y. Qiu ; W. Xie ; F. Yue ; M. Hariharan ; P. Ray ; S. Kuan ; L. Edsall ; H. Yang ; N. C. Chi ; M. Q. Zhang ; J. R. Ecker ; B. Ren
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-02-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Acetylation ; *Alleles ; Chromatin/genetics/metabolism ; Chromosomes, Human/genetics ; Datasets as Topic ; Enhancer Elements, Genetic/genetics ; Epigenesis, Genetic/*genetics ; *Epigenomics ; Genetic Variation/genetics ; Haplotypes/*genetics ; Histones/metabolism ; Humans ; Nucleotide Motifs ; Organ Specificity/genetics ; Transcription, Genetic/geneticsPublished by: -
2Latest Papers from Table of Contents or Articles in PressA. Kundaje ; W. Meuleman ; J. Ernst ; M. Bilenky ; A. Yen ; A. Heravi-Moussavi ; P. Kheradpour ; Z. Zhang ; J. Wang ; M. J. Ziller ; V. Amin ; J. W. Whitaker ; M. D. Schultz ; L. D. Ward ; A. Sarkar ; G. Quon ; R. S. Sandstrom ; M. L. Eaton ; Y. C. Wu ; A. R. Pfenning ; X. Wang ; M. Claussnitzer ; Y. Liu ; C. Coarfa ; R. A. Harris ; N. Shoresh ; C. B. Epstein ; E. Gjoneska ; D. Leung ; W. Xie ; R. D. Hawkins ; R. Lister ; C. Hong ; P. Gascard ; A. J. Mungall ; R. Moore ; E. Chuah ; A. Tam ; T. K. Canfield ; R. S. Hansen ; R. Kaul ; P. J. Sabo ; M. S. Bansal ; A. Carles ; J. R. Dixon ; K. H. Farh ; S. Feizi ; R. Karlic ; A. R. Kim ; A. Kulkarni ; D. Li ; R. Lowdon ; G. Elliott ; T. R. Mercer ; S. J. Neph ; V. Onuchic ; P. Polak ; N. Rajagopal ; P. Ray ; R. C. Sallari ; K. T. Siebenthall ; N. A. Sinnott-Armstrong ; M. Stevens ; R. E. Thurman ; J. Wu ; B. Zhang ; X. Zhou ; A. E. Beaudet ; L. A. Boyer ; P. L. De Jager ; P. J. Farnham ; S. J. Fisher ; D. Haussler ; S. J. Jones ; W. Li ; M. A. Marra ; M. T. McManus ; S. Sunyaev ; J. A. Thomson ; T. D. Tlsty ; L. H. Tsai ; W. Wang ; R. A. Waterland ; M. Q. Zhang ; L. H. Chadwick ; B. E. Bernstein ; J. F. Costello ; J. R. Ecker ; M. Hirst ; A. Meissner ; A. Milosavljevic ; B. Ren ; J. A. Stamatoyannopoulos ; T. Wang ; M. Kellis
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-02-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Base Sequence ; Cell Lineage/genetics ; Cells, Cultured ; Chromatin/chemistry/genetics/metabolism ; Chromosomes, Human/chemistry/genetics/metabolism ; DNA/chemistry/genetics/metabolism ; DNA Methylation ; Datasets as Topic ; Enhancer Elements, Genetic/genetics ; Epigenesis, Genetic/*genetics ; *Epigenomics ; Genetic Variation/genetics ; Genome, Human/*genetics ; Genome-Wide Association Study ; Histones/metabolism ; Humans ; Organ Specificity/genetics ; RNA/genetics ; Reference ValuesPublished by: -
3Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-10-12Publisher: Institute of Physics (IOP)Print ISSN: 1755-1307Electronic ISSN: 1755-1315Topics: GeographyGeosciencesPhysicsPublished by: -
4Latest Papers from Table of Contents or Articles in PressW. Ouyang ; W. Liao ; C. T. Luo ; N. Yin ; M. Huse ; M. V. Kim ; M. Peng ; P. Chan ; Q. Ma ; Y. Mo ; D. Meijer ; K. Zhao ; A. Y. Rudensky ; G. Atwal ; M. Q. Zhang ; M. O. Li
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-11-09Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Binding Sites ; Cell Nucleus/metabolism/pathology ; Female ; Forkhead Transcription Factors/*metabolism ; Gene Expression Regulation/genetics ; Genome/genetics ; Immune Tolerance/genetics/immunology ; Interferon-gamma/deficiency/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Antigen, T-Cell/immunology/metabolism ; Signal Transduction ; T-Lymphocytes, Regulatory/*immunology/*metabolism/pathology ; *Transcription, GeneticPublished by: -
5Articles: DFG German National LicensesStaff View
ISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: We use the capillary wave model of a liquid–vapor interface as a working example to show how to construct the free energy density functional from studies of the direct correlation functions of a reference system, and vise versa.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The free energy of a classical nonuniform fluid is developed in a density functional expansion defined recursively from mean field theory as a starting point. Capillary wave contributions to the structure of a two-fluid interface appear explicitly in the first order. The first order result is worked out as well in the general case of slowly varying density. Comparison with potential ensemble theory is also made.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 1089-7658Source: AIP Digital ArchiveTopics: MathematicsPhysicsNotes: Exact k-space density response of a perfect Fermion (spinless) fluid in the ground state to external potentials is derived in a closed form to all orders in two dimensions. The results are expressed in terms of geometrical invariants. The most distinct features in two dimensions are that no short wave-vector response depends on kF (the Fermi wave vector), and the usual first-order linear response function R˜(k) is a constant for k≤2kF.Type of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0375-9601Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 1572-9613Keywords: Nonequilibrium stationary states ; stochastic lattice gas ; high-temperature approximations ; pair correlations ; power law decaySource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract We report computer simulations and high-temperature approximations of the pair correlation in a stationary nonequilibrium system, a lattice gas subject to a strong uniform driving fieldE. The dynamics of the system is given by hoppings of particles to adjacent empty sites with rates biased for jumps in the direction ofE. We study the anisotropic short-distance behavior as well as the long-distance decay properties of the two-point correlations along the principal axes. The simulations as well as the (approximate) expansion inβ strongly suggest that the correlations in this system have a power law decay,r −D for dimensionsD=2 and 3, even at high temperatures.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1572-9613Keywords: Competing dynamics ; nonequilibrium steady state ; pair correlation functionSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract An interacting Ising spin system on a lattice with the competing influence of spin-flip (Glauber) and spin-exchange (Kawasaki) dynamics is studied. The exact nonequilibrium steady-state solution of the pair correlation function in one dimension is derived and compared with the simulation data. The two-dimensional solution, under some Ansatz, is also discussed.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1572-9613Keywords: Inverse solution ; inhomogeneous Ising network ; collective modes ; topological invariantsSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract We first generalize the inhomogeneous external field Ising model on a ring to include inhomogeneous couplings. We then further generalize the one-dimensional periodic lattice to the simplest multiconnected networks. The fundamental idea and techniques developed here may be also applicable to other problems where topological collective (nonlocal) modes are many fewer in number than total degrees of freedom.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1420-908XSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract A series of terfenadine derivatives were evaluated for enantioselectivity on histamine H1-receptors and calcium channels. Whereas H1-receptors are only sterically discriminative against the benzhydryl part of the molecules, calcium channels showed enantioselectivity to either the phenylbutyl part or the benzhydryl part provided that an appropriate lipophilicity is preserved at the chiral site. It is speculated that the hydrophilicity of the butanol moiety is responsible for the lack of stereoselectivity of terfenadine enantiomers since it drives the side chain out the stereoselective site of calcium channels, which are lipophilic. In four different test systems, (guinea-pig ileum, guinea-pig lung membranes, rat aorta and rat cortex mebranes), this series of compounds generally showed about 10 times higher activity on H1-receptors than on calcium channels. By introducing a chiral center in the different parts of the molecule we were able to increase the selectivity of an enantiomer VUF4648 to calcium channels.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1420-908XSource: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1420-908XSource: Springer Online Journal Archives 1860-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1432-0916Source: Springer Online Journal Archives 1860-2000Topics: MathematicsPhysicsNotes: Abstract We show explicitly how to construct the quantum Lax pair from the Yang-Baxter equation. We demonstrate the new method by applying it to the Heisenberg XYZ model.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1572-9613Keywords: Stationary nonequilibrium states ; driven lattice gas ; van Kampen'sΩ-expansion ; Maxwell constructionSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract We study the stationary nonequilibrium states of the van Beijeren/Schulman model of a driven lattice gas in two dimensions. In this model, jumps are much faster in the direction of the driving force than orthogonal to it. Van Kampen's Ω-expansion provides a suitable description of the model in the high-temperature region and specifies the critical temperature and the spinodal curve. We find the rate dependence ofT c and show that independently of the jump rates the critical exponents of the transition are classical, except for anomalous energy fluctuations. We then study the stationary solution of the deterministic equations (zeroth-orderΩ-expansion). They can be obtained as trajectories of a dissipative dynamical system with a three-dimensional phase space. Within a certain temperature range belowT c, these equations have a kink solution whose asymptotic densities we identify with those of phase coexistence. They appear to coincide with the results of the “Maxwell construction.” This provides a dynamical justification for the use of this construction in this nonequilibrium model. The relation of the Freidlin-Wentzell theory of small random perturbations of dynamical systems to the steady-state distribution belowT c is discussed.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1572-9613Keywords: Hard-rod fluid ; nonuniform ; variational principle ; Wiener-Hopf factorization ; scaled particle theorySource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract The statistical mechanics of the one-dimensional nonuniform pure hard-core fluid is formulated in the spirit of the Reiss-Frisch-Lebowitz (RFL) scaled particle theory. By emphasizing the importance of the core dependence, a more intuitive and simpler derivation can be given. The Wiener-Hopf-type construction of the pair direct correlation function is formulated via the Dyson variational method of inverse scattering theory, which is compared with the particle-hole theory. The new approach allows us to lift the global free energy functional into a larger space where all the symmetries become apparent.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1572-9613Keywords: Vectorized multispin coding on Cyber 205 ; 3D Monte Carlo algorithm ; Kawasaki dynamics ; conservation lawSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract A new Monte Carlo algorithm for 3D Kawasaki spin-exchange simulations and its implementation on a CDC CYBER 205 is presented. This approach is applicable to lattices with sizes between 4×4×4 and 256×L2×L3 ((L2+2)(L3+4)/4⩽65535) and periodic boundary conditions. It is adjustable to various kinetic models in which the total magnetization is conserved. Maximum speed on 10 million steps per second can be reached for 3-D Ising model with Metropolis rate.Type of Medium: Electronic ResourceURL: