Search Results - (Author, Cooperation:M. Platzer)
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1K. F. Mayer ; R. Waugh ; J. W. Brown ; A. Schulman ; P. Langridge ; M. Platzer ; G. B. Fincher ; G. J. Muehlbauer ; K. Sato ; T. J. Close ; R. P. Wise ; N. Stein
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-10-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Alternative Splicing/genetics ; Codon, Nonsense/genetics ; Crops, Agricultural/genetics ; Evolution, Molecular ; Gene Expression Regulation, Plant ; Genes, Plant/genetics ; Genome, Plant/*genetics ; Genomics ; Hordeum/classification/*genetics ; Molecular Sequence Annotation ; Physical Chromosome Mapping ; Polymorphism, Single Nucleotide/genetics ; Repetitive Sequences, Nucleic Acid/genetics ; *Sequence Analysis, DNA ; Transcriptome/geneticsPublished by: -
2Bottger, M. ; Vogel, F. ; Platzer, M. ; Kiessling, U. ; Grade, K. ; Strauss, M.
Amsterdam : ElsevierStaff ViewISSN: 0167-4781Keywords: Chromosomal protein ; DNA condensation ; DNA transfection ; High mobility group protein 1 ; Transfection ; Vector DNASource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
3Platzer, M. H. ; Grattan, C. E. H. ; Poulsen, L. K. ; Skov, P. S.
Oxford, UK : Munksgaard International Publishers
Published 2005Staff ViewISSN: 1398-9995Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Background: Endogenous histamine-releasing factors (HRFs) are involved in 30–60% of patients with chronic urticaria (CU). Evidence for their existence comes from in vivo studies of autoreactivity with the autologous serum skin test (ASST), in vitro immunoassays demonstrating autoantibodies against the immunoglobulin E (IgE) or the high affinity IgE receptor (FcɛRI) and serum-induced histamine release (HR) from basophils and mast cells. We have examined the correlation between the ASST and a new basophil histamine-releasing assay (the HR-Urtikaria test) in a group of well-characterized CU patients and subsequently determined the frequency of HR-Urticaria-positive sera from a larger population of CU patients.Subjects: Group 1 consisted of 28 patients with CU (16 were ASST-positive) 20 patients with atopic dermatitis, 24 patients with allergy to birch and nine healthy controls. Group 2 consisted of 873 unselected CU patients.Methods: White blood cells containing 1–2% basophils from a healthy nonatopic donor were incubated with patients sera in the presence of interleukin (IL)-3. Histamine was measured by the glass fibre method.Results: Using the ASST as the true outcome, the HR-Urticaria test showed a sensitivity and specificity of 75% in group 1 using a cut-off value for HR of 〉16.5%. None of the controls was positive in the HR-Urticaria test. In group 2, we found no difference in the frequency of positives between male (34.6%, n = 254) and female adults (35.1%, n = 576) but twice as many females as males were tested.Conclusions: Our studies have shown that the HR-Urticaria test has a good sensitivity and specificity for endogenous HRFs demonstrated by the ASST in patients with CU and that about one-third of unselected patients with CU have a positive result.Type of Medium: Electronic ResourceURL: -
4Watanabe, H. ; Fujiyama, A. ; Hattori, M. ; Taylor, T. D. ; Toyoda, A. ; Kuroki, Y. ; Noguchi, H. ; BenKahla, A. ; Lehrach, H. ; Sudbrak, R. ; Kube, M. ; Taenzer, S. ; Galgoczy, P. ; Platzer, M. ; Scharfe, M. ; Nordsiek, G. ; Blöcker, H. ; Hellmann, I. ; Khaitovich, P. ; Pääbo, S. ; Reinhardt, R. ; Zheng, H.-J. ; Zhang, X.-L. ; Zhu, G.-F. ; Wang, B.-F.
[s.l.] : Macmillian Magazines Ltd.
Published 2004Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] Human–chimpanzee comparative genome research is essential for narrowing down genetic changes involved in the acquisition of unique human features, such as highly developed cognitive functions, bipedalism or the use of complex language. Here, we report the high-quality DNA sequence of 33.3 ...Type of Medium: Electronic ResourceURL: -
5Krause, H. ; Garajev, M.M. ; Geissler, E. ; Platzer, M. ; Scherneck, S. ; Zimmermann, W.
Amsterdam : ElsevierStaff ViewISSN: 0378-1119Keywords: Recombinant DNA ; Southern hybridization ; brain tumors ; electron microscopy ; heteroduplex analysis ; restriction endonuclease mappingSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 0168-1656Keywords: EST ; Human genome project ; PCR ; STS ; cDNA extensionSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 0303-7207Keywords: Cyclic AMP ; Thyrocyte/T cell hybridoma,human ; Thyroid-stimulating hormoneSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
8DAVIES, T. F. ; WEBER, C. M. ; WALLACK, P. ; PLATZER, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1986Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1432-1114Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract An experimental investigation of the high-incidence vortical flowfield over a 76/40° double-delta wing model with sharp leading edges was conducted in the Naval Postgraduate School water tunnel facility at three nominal flow Reynolds numbers of 15000, 45000, and 75000 (based on centerline chord). Extensive flow visualization studies were performed with the dye-injection technique, followed by laser Doppler velocity measurements. The primary objective of this investigation was the determination of the influence of Reynolds number on vortex interactions/trajectories, and breakdown. It was found that there is a significant influence of Reynolds number. Specifically, with the increase of flow Reynolds number the strake and wing vortex trajectories tend to move outboards and closer to the model surface, and the vortex breakdown location moves forwards toward the apex of the model. The intertwining or coiling-up feature of the vortex interaction phenomenon becomes less dominant and disappears altogether at high Reynolds numbers. These trends in the vortex interaction and bursting data are found to be in good agreement with previous wind tunnel data.Type of Medium: Electronic ResourceURL: -
10Kiselev, N. A. ; Stel'mashchuk, V. Ya. ; Orlova, E. V. ; Platzer, M. ; Noll, F. ; Bielka, H.
Springer
Published 1982Staff ViewISSN: 1573-4978Source: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract An optical averaging of rat liver ribosome small subunit images revealed seven ‘strands’ with a mean diameter of about 50 Å. A tentative model of the 3D arrangement of the ‘strands’ is suggested. An assumption is made that these ‘strands’ are clusters of protein molecules arranged on the double-helical regions of RNA.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1619-6937Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsDescription / Table of Contents: Zusammenfassung Es wird die Überschallströmung um schwingende Profile in einem Windkanal mit poröser Wand untersucht. Ausgehend von der von Sauer angegebenen Lösung für den langsam schwingenden Flügel in einer unbegrenzten Überschallströmung wird gezeigt, wie diese Lösung erweitert werden kann, um Kanalinterferenz miteinzuschließen. Diese neue elementare Theorie wird mit einer früheren Lösung von Drake, welcher Laplace-Transformations-methoden verwendete, und einem Charakteristikenverfahren von Platzer und Pierce verglichen.Notes: Summary Supersonic flow past a slowly oscillating two-dimensional airfoil in a wind tunnel with porous walls is considered. Starting from Sauer's solution for the slowly oscillating airfoil in an unbounded supersonic flow it is shown how this solution can be extended to take wall interference into account. This new and quite elementary theory is compared with an earlier analysis by Drake using Laplace-transform techniques and with a method of characteristics solution by Platzer and Pierce.Type of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 1619-6937Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsDescription / Table of Contents: Zusammenfassung Es wird die Überschallströmung um langsam schwingende spitze Rotationskörper untersucht. Ausgehend von der vollständigen nichtlinearen Potentialgleichung wird zuerst eine elementare linearisierte Lösung besprochen und gezeigt, wie diese Lösung im Verein mit der “Method of matched asymptotic expansions” zur Herleitung einer elementaren Schlankkörpertheorie zweiter Ordnung verwendet werden kann. Die Theorie wird am Beispiel des schwingenden Kegels näher erläutert und mit anderen Methoden verglichen.Notes: Summary Supersonic flow past slowly oscillating pointed bodies of revolution is studied. Starting from the complete nonlinear potential equation an elementary linearized solution is discussed and it is shown how this solution together with the method of matched asymptotic expansions can be used to derive an elementary second-order slender body theory. This approach is further demonstrated for the oscillating cone and its range of validity is evaluated by comparison with other theoretical methods.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1619-6937Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsPhysicsDescription / Table of Contents: Summary An approximation theory is developed for the calculation of linearized subsonic and supersonic flow over pulsating low aspect ratio bodies. The resulting flow field is shown to exhibit a similar structure as found byK. Oswatitsch andF. Keune for steady flow around low aspect ratio bodies at zero angle of attack. The range of validity of this approximation theory is demonstrated by comparing it with exact solutions of the unsteady linearized potential equation.Notes: Zusammenfassung Es wird eine Näherungstheorie zur Berechnung der linearisierten Unter- und Überschallströmung um pulsierende Körper kleiner Streckung entwickelt. Das Strömungsfeld hat eine ähnliche Struktur wie die vonK. Oswatitsch undF. Keune angegebene stationäre Strömung um Körper kleiner Streckung für den Anstellwinkel Null. Der Geltungsbereich der Näherungstheorie wird durch Vergleich mit exakten Lösungen der instationären, linearisierten Potentialgleichung erläutert.Type of Medium: Electronic ResourceURL: -
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ISSN: 0138-4988Keywords: Life Sciences ; Life Sciences (general)Source: Wiley InterScience Backfile Collection 1832-2000Topics: Process Engineering, Biotechnology, Nutrition TechnologyType of Medium: Electronic ResourceURL: