Search Results - (Author, Cooperation:M. Noble)
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1Latest Papers from Table of Contents or Articles in PressShaun K. Wilson, Martial Depcyznski, Rebecca Fisher, Thomas H. Holmes, Mae M. Noble, Ben T. Radford, Michael Rule, George Shedrawi, Paul Tinkler, Christopher J. Fulton
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-01-17Publisher: Wiley-BlackwellElectronic ISSN: 2045-7758Topics: BiologyPublished by: -
2Latest Papers from Table of Contents or Articles in PressM. S. Lawrence ; P. Stojanov ; P. Polak ; G. V. Kryukov ; K. Cibulskis ; A. Sivachenko ; S. L. Carter ; C. Stewart ; C. H. Mermel ; S. A. Roberts ; A. Kiezun ; P. S. Hammerman ; A. McKenna ; Y. Drier ; L. Zou ; A. H. Ramos ; T. J. Pugh ; N. Stransky ; E. Helman ; J. Kim ; C. Sougnez ; L. Ambrogio ; E. Nickerson ; E. Shefler ; M. L. Cortes ; D. Auclair ; G. Saksena ; D. Voet ; M. Noble ; D. DiCara ; P. Lin ; L. Lichtenstein ; D. I. Heiman ; T. Fennell ; M. Imielinski ; B. Hernandez ; E. Hodis ; S. Baca ; A. M. Dulak ; J. Lohr ; D. A. Landau ; C. J. Wu ; J. Melendez-Zajgla ; A. Hidalgo-Miranda ; A. Koren ; S. A. McCarroll ; J. Mora ; R. S. Lee ; B. Crompton ; R. Onofrio ; M. Parkin ; W. Winckler ; K. Ardlie ; S. B. Gabriel ; C. W. Roberts ; J. A. Biegel ; K. Stegmaier ; A. J. Bass ; L. A. Garraway ; M. Meyerson ; T. R. Golub ; D. A. Gordenin ; S. Sunyaev ; E. S. Lander ; G. Getz
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-06-19Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Artifacts ; DNA Replication Timing ; Exome/genetics ; False Positive Reactions ; Gene Expression ; *Genetic Heterogeneity ; Genome, Human/genetics ; Humans ; Lung Neoplasms/genetics ; Mutation/*genetics ; Mutation Rate ; Neoplasms/classification/*genetics/pathology ; Neoplasms, Squamous Cell/genetics ; Oncogenes/*genetics ; Reproducibility of Results ; Sample SizePublished by: -
3Articles: DFG German National LicensesStaff View
ISSN: 0002-9106Keywords: Life and Medical Sciences ; Cell & Developmental BiologySource: Wiley InterScience Backfile Collection 1832-2000Topics: MedicineType of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesGoguenheim, Didier ; Vuillaume, Dominique ; Vincent, Gilbert ; Johnson, Noble M.
[S.l.] : American Institute of Physics (AIP)
Published 1990Staff ViewISSN: 1089-7550Source: AIP Digital ArchiveTopics: PhysicsNotes: A measurement technique and analysis are presented for the accurate determination of the capture cross sections of the interface states in metal-oxide-semiconductor (MOS) structures. The technique utilizes the interface-trap-filling kinetics during measurements by energy-resolved deep level transient spectroscopy (DLTS). High accuracy is attained by accounting in the analysis for the charge-potential feedback effect which is a unique feature of the MOS structure and which presents a critical difficulty in the DLTS measurement of capture cross sections in MOS devices. The accurate measurement of the capture cross sections obtained in this work allows us to study several electronic properties of the Si-SiO2 interface including (i) the behavior of the capture cross sections of interface states created by high-field stress on MOS devices, and (ii) the determination of the capture cross section of dangling bonds at the 〈100〉-oriented Si-SiO2 interface. Finally, the possibility of determining the degeneracy factor of the interface states is questioned.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesMAGOS, A. L. ; NOBLE, M. C. B. ; WONG TEN YUEN, A. ; RODECK, C. H.
Oxford, UK : Blackwell Publishing Ltd
Published 1983Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Summary. In a prospective randomized study, 36 patients with spontaneous rupture of the membranes of ≥4 h duration were stimulated with 3 mg vaginal prostaglandin E2 pessaries or intravenous oxytocin. Oxytocin stimulation was associated with shorter labours and a lower incidence of abnormal cervimetric progress. Of the patients given prostaglandin pessaries, 40% required a second dose after 4 h for slow progress; 45% of the primigravidae subsequently developed abnormal labour which was corrected by augmentation with oxytocin in all cases. One caesarean section was carried out for disproportion, and the remaining 35 patients were delivered vaginally. Prostaglandin pessaries were not associated with an increased incidence of hyperstimulation or sepsis. In conclusion, although PGE2 pessaries are safe in spontaneous rupture of the membranes, intravenous oxytocin is more efficient in stimulating labour.Type of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Serial changes in 24-hour creatinine clearance were determined in 11 women during several menstrual cycles before conception, the conceptional cycle and the first trimester of pregnancy. During the menstrual cycle, a 20 per cent mean increase occurred between the week of menstruation and the late luteal phase. Following conception, this increase continued such that a 45 per cent mean increase was evident by the ninth week of gestation. In two women who aborted spontaneously, the change in 24-hour creatinine clearance in early pregnancy was not as great nor as sustained, this feature being apparent at least three weeks before any clinical abnormality. Possible reasons for the changes in glomerular filtration rate in early pregnancy and its clinical implications are discussed.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesNoble, M. C. B. ; Landon, M. J. ; Dvison, J. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1978Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesNoble, M. C. B. ; Landon, M. J. ; Davison, J. M.
Oxford, UK : Blackwell Publishing Ltd
Published 1977Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: A cross-sectional study of γ-glutamyl transferase (γ-GT) excretion in 316 healthy pregnant women showed the enzyme excretion (mU per mmol creatinine) was significantly higher than that of a non-pregnant control group. The increase was apparent before the end of the first trimester and continued thereafter. These changes may be indicative of hypertrophy and/or hyperplasia of the nephron and be part of the overall renal adaptation to normal pregnancy. Even higher levels were recorded in three obstetric patients in whom renal complications were to be expected and this may indicate a specific type of renal damage.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesKneissl, Michael ; Bour, David P. ; Van de Walle, Chris G. ; Romano, Linda T. ; Northrup, John E. ; Wood, Rose M. ; Teepe, Mark ; Johnson, Noble M.
Woodbury, NY : American Institute of Physics (AIP)
Published 1999Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Room-temperature continuous-wave (cw) operation is demonstrated with InGaN multiple-quantum-well laser diodes containing an asymmetric waveguide structure. Pulsed threshold current densities as low as 5.2 kA/cm2 have been obtained for ridge-waveguide laser diodes grown on sapphire substrates by metal-organic chemical vapor deposition. For improved thermal management, the sapphire substrate was thinned and the devices were mounted p side up onto a copper heatsink. Under cw conditions at 20 °C, threshold current densities were 8.3 kA/cm2 with threshold voltages of 6.3 V. The emission wavelength was 401 nm with output powers greater than 3 mW per facet. Under cw conditions, laser oscillation was observed up to 25 °C. The room-temperature cw operation lifetimes, for a constant current, exceeded one hour. © 1999 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesKneissl, Michael ; Paoli, Thomas L. ; Kiesel, Peter ; Treat, David W. ; Teepe, Mark ; Miyashita, Naoko ; Johnson, Noble M.
Woodbury, NY : American Institute of Physics (AIP)
Published 2002Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Q-switching is demonstrated in a two-section InGaN multiple-quantum-well (MQW) laser diode consisting of an electroabsorption modulator and amplifier (gain) section. The modulator and gain sections are optically coupled and share the same InGaN MQW active region, but they are electrically separated by a narrow dry-etched trench. Applying a reverse bias voltage to the modulator section controls the absorption in the modulator portion of the device by compensating the piezoelectric field in the InGaN quantum wells. Changes in the absorption coefficient as large as 5000 cm−1 were realized with a moderate reverse bias of 7.2 V. By forward biasing, the amplifier section at a constant current of 225 mA and by controlling the reverse bias modulator voltage, the output power of the two-section laser diode could be switched between 〈0.5 mW (off state) and more than 3 mW (on state) with a laser emission wavelength near 401 nm. © 2002 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesWong, William S. ; Kneissl, Michael ; Mei, Ping ; Treat, David W. ; Teepe, Mark ; Johnson, Noble M.
Woodbury, NY : American Institute of Physics (AIP)
Published 2001Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: Continuous-wave (cw) indium-gallium nitride multiple-quantum-well laser diodes (LDs) were transferred from sapphire onto copper substrates using a two-step laser lift-off process. Reduced threshold currents and increased differential quantum efficiencies were measured for LDs on Cu due to a 50% reduction of the thermal impedance. Light output for LDs on Cu was three times greater than comparable LDs on sapphire with a maximum output of 30 mW. CW operation was possible up to heatsink temperatures of 90 °C for LDs on Cu. © 2001 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesKneissl, Michael ; Bour, David P. ; Romano, Linda ; Van de Walle, Chris. G. ; Northrup, John E. ; Wong, William S. ; Treat, David W. ; Teepe, Mark ; Schmidt, Tanya ; Johnson, Noble M.
Woodbury, NY : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1077-3118Source: AIP Digital ArchiveTopics: PhysicsNotes: The performance and degradation characteristics of continuous-wave (cw) InGaN multiple-quantum-well laser diodes are reported. A cw threshold current as low as 62 mA was obtained for ridge-waveguide laser diodes on epitaxially laterally overgrown GaN on sapphire substrates grown by metalorganic chemical vapor deposition. Transmission electron microscopy reveals a defect density 〈5×107 cm−2 in the active region. The emission wavelength was near 400 nm with output powers greater than 20 mW per facet. Under cw conditions, laser oscillation was observed up to 70 °C. The room-temperature cw operation lifetimes, measured at a constant output power of 2 mW, exceeded 15 h. From the temperature dependence of the laser diode lifetimes, an activation energy of 0.50 eV±0.05 eV was determined. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesFORSSMANN, W. G. ; TRIEPEL, J. ; DAFFNER, C. ; HEYM, CH. ; CUEVAS, P. ; NOBLE, M. I. M. ; YANAIHARA, N.
Oxford, UK : Blackwell Publishing Ltd
Published 1988Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesSvensen, T. C. ; Parsons, F. M. ; McCracken, B. H. ; Noble, M. J. D.
Oxford, UK : Blackwell Publishing Ltd
Published 1960Staff ViewISSN: 1471-0528Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesWOLSWIJK, GUUS ; MUNRO, PETER M. G. ; RIDDLE, PETER N. ; NOBLE, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1991Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesCRANG, A. J. ; FRANKLIN, R. J. M. ; BLAKEMORE, W. F. ; TROTTER, J. ; SCHACHNER, M. ; BARNETT, S. C. ; NOBLE, M.
Oxford, UK : Blackwell Publishing Ltd
Published 1991Staff ViewISSN: 1749-6632Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Natural Sciences in GeneralType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesNoble, M. ; Qian, C. X. W. ; Reisler, H. ; Wittig, C.
College Park, Md. : American Institute of Physics (AIP)
Published 1986Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: The predissociation of jet-cooled (CH3)3CNO (t-BuNO) following laser excitation in the A˜ 1A‘←X˜ 1A' system has been studied in both the energy (frequency) and time domains. Unlike the smaller nitroso compounds whose predissociation has been already examined, unimolecular reaction is the rate determining step for predissociation near threshold. Consequently, it has been possible to separately measure radiationless transition rates and unimolecular reaction rates in real time. Dissociation on both the ground state (S0) and the first triplet state (T1) has been identified. At threshold, dissociation proceeds only on S0, with lifetimes 〉3.5 μs, but for E°≥650 cm−1, fast (〈10 ns) predissociation via T1 becomes progressively the dominant dissociative route. Nascent NO photofragments have been characterized in detail using one-photon LIF. The rotational and spin-orbit distributions of NO following dissociation on S0 are statistical, depending only on E°. The NO derived from dissociation on the T1 surface is not at all statistical, consistent with a sizable (∼650 cm−1) exit channel barrier on this surface. Most notably, the [NO(2Π3/2)]/[NO(2Π1/2)] ratios are much smaller, and rotational distributions are colder than predicted by a statistical model. In order that some of the predissociating vibrational states could be assigned, the 1A‘←1A' spectrum of t-BuNO has been analyzed and the electronic origin assigned as 13 911 cm−1. The ground state dissociation energy, D0, is found to be 13 930±30 cm−1, i.e., 39.8±0.1 kcal mol−1.Type of Medium: Electronic ResourceURL: