Search Results - (Author, Cooperation:M. Mirza)
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1Latest Papers from Table of Contents or Articles in PressFang, M. M., Barman, P. K., Thiruppathi, M., Mirza, R. E., McKinney, R. D., Deng, J., Christman, J. W., Du, X., Fukai, T., Ennis, W. J., Koh, T. J., Ushio-Fukai, M., Urao, N.
The American Association of Immunologists (AAI)
Published 2018Staff ViewPublication Date: 2018-10-10Publisher: The American Association of Immunologists (AAI)Print ISSN: 0022-1767Electronic ISSN: 1550-6606Topics: MedicinePublished by: -
2Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2018-10-05Publisher: BMJ Publishing GroupTopics: MedicinePublished by: -
3Latest Papers from Table of Contents or Articles in PressCheung, A., Opzoomer, J., Ilieva, K. M., Gazinska, P., Hoffmann, R. M., Mirza, H., Marlow, R., Francesch-Domenech, E., Fittall, M., Dominguez Rodriguez, D., Clifford, A., Badder, L., Patel, N., Mele, S., Pellizzari, G., Bax, H. J., Crescioli, S., Petranyi, G., Larcombe-Young, D., Josephs, D. H., Canevari, S., Figini, M., Pinder, S., Nestle, F. O., Gillett, C., Spicer, J. F., Grigoriadis, A., Tutt, A. N. J., Karagiannis, S. N.
The American Association for Cancer Research (AACR)
Published 2018Staff ViewPublication Date: 2018-10-16Publisher: The American Association for Cancer Research (AACR)Print ISSN: 1078-0432Electronic ISSN: 1557-3265Topics: MedicinePublished by: -
4Latest Papers from Table of Contents or Articles in PressC. Busche ; L. Vila-Nadal ; J. Yan ; H. N. Miras ; D. L. Long ; V. P. Georgiev ; A. Asenov ; R. H. Pedersen ; N. Gadegaard ; M. M. Mirza ; D. J. Paul ; J. M. Poblet ; L. Cronin
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-11-20Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
5Latest Papers from Table of Contents or Articles in PressK. A. Hunt ; V. Mistry ; N. A. Bockett ; T. Ahmad ; M. Ban ; J. N. Barker ; J. C. Barrett ; H. Blackburn ; O. Brand ; O. Burren ; F. Capon ; A. Compston ; S. C. Gough ; L. Jostins ; Y. Kong ; J. C. Lee ; M. Lek ; D. G. MacArthur ; J. C. Mansfield ; C. G. Mathew ; C. A. Mein ; M. Mirza ; S. Nutland ; S. Onengut-Gumuscu ; E. Papouli ; M. Parkes ; S. S. Rich ; S. Sawcer ; J. Satsangi ; M. J. Simmonds ; R. C. Trembath ; N. M. Walker ; E. Wozniak ; J. A. Todd ; M. A. Simpson ; V. Plagnol ; D. A. van Heel
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-05-24Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Autoimmune Diseases/*genetics ; European Continental Ancestry Group/genetics ; Exons/genetics ; Gene Frequency ; Genetic Predisposition to Disease/*genetics ; Genetic Variation/*genetics ; Genome-Wide Association Study ; Great Britain ; Humans ; Models, Genetic ; Mutation/genetics ; Open Reading Frames/*genetics ; Phenotype ; Sample SizePublished by: -
6Articles: DFG German National LicensesStaff View
ISSN: 1365-3059Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Sclerotium rolfsii was isolated from diseased rhizomes of greenhouse–grown Alstroemeria (Alstroemeria sp.) in Edmonton in 1992. The underground portions of the plants were attacked resulting in leaf chlorosis which started on the lower leaves and gradually moved upwards. The characteristics of the isolates from diseased Alstroemeria were compared with those from other crops. This is the first report of S. rolfsii on Alstroemeria in Canada.Type of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0003-2697Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesBarton, D. C. ; Mirza, M. S. ; Waheed, M. ; Sturges, J. L. ; Church, P.
Oxford, UK : Blackwell Publishing Ltd
Published 1997Staff ViewISSN: 1460-2695Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract— High strain-rate tensile tests have been carried out on pre-notched specimens of OFHC copper and Remko iron at both elevated and cryogenic temperatures. When properly expressed as a function of stress triaxiality at the centre of the notch (as predicted by numerical simulations of the experiment), the ductility of copper was found to be independent of temperature over a range from —190°C to 300°C. The specially-processed Remko iron was found to undergo a ductile-to-brittle transition at a temperature dependent on the stress triaxiality and the particular batch of the material. Otherwise the fully ductile strains-to-failure (when expressed as a function of stress triaxiality) for iron were found to decrease with increasing temperature up to 400°C; this being the maximum temperature tested.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 1460-2695Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract— An experimental investigation was conducted on a series of simply supported concrete beams with an aim to determine the fracture energy of the composite beam and apply the concept of fracture mechanics to predict flexural strength. In order that a single crack from the tip of the premolded central notch would propagate, the beams were lightly reinforced with a large cover so that the moment capacity of the beam as unreinforced section would be greater than that of the reinforced section. Based on test data, compliance calibration and energy release rate (G1) curves are presented for progressive cracking and a correlation between the critical energy release rate and ultimate moment capacity is suggested.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 1399-3054Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyNotes: Frankia strains have been isolated from actinorhizal nodules of Alnus (2 strains), Casuarina (5 strains), Coriaria (1 strain), Datisca (3 strains), Elaeagnus (1 strain) and Hippophae (1 strain). The isolates were characterized for their growth on various carbon and nitrogen sources, nitrogen-fining ability in culture and nodulation of seedlings of the original host plant.Type of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesOlavesen, M. ; Hampe, J. ; Mirza, M. M. ; Saiz, R. ; Lewis, C. M. ; Bridger, S. ; Teare, D. ; Easton, D. F. ; Herrmann, T. ; Scott, G. ; Hirst, J. ; Sanderson, J. ; Hodgson, S. V. ; Lee, J. ; MacPherson, A. ; Schreiber, S. ; Lennard-Jones, J. E. ; Curran, M. E. ; Mathew, C. G.
Springer
Published 2000Staff ViewISSN: 1432-1211Keywords: Key words Inflammatory bowel ; Crohn's ; Ulcerative colitis ; Interleukin-4 receptor ; AssociationSource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract Genetic linkage analysis in families with multiple cases of inflammatory bowel disease (IBD) has mapped a gene which confers susceptibility to IBD to the pericentromeric region of chromosome 16 (IBD1). The linked region includes the interleukin(IL)-4 receptor gene (IL4R). Since IL-4 regulation and expression are abnormal in IBD, the IL4R gene is thus both a positional and functional candidate for IBD1. We screened the gene for single-nucleotide polymorphisms (SNPs) by fluorescent chemical cleavage analysis, and tested a subset of known and novel SNPs for allelic association with IBD in 355 families, which included 435 cases of Crohn's disease and 329 cases of ulcerative colitis. No association was observed between a haplotype of four SNPs (val50ile, gln576arg, A3044G, G3289A) and either the Crohn's disease or ulcerative colitis phenotypes using the transmission disequilibrium test. There was also no evidence for association when the four markers were analyzed individually. The results indicate that these variants are not significant genetic determinants of IBD, and that the IL4R gene is unlikely to be IBD1. Linkage disequilibrium analyses showed that the val50ile and gln576arg variants are in complete equilibrium with each other, although they are separated by only about 21 kilobases of genomic DNA. This suggests that a very dense SNP map may be required to exclude or detect disease associations with some candidate genes.Type of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 1432-1009Keywords: KEY WORDS: Bangladesh; Ganges River; Gorai River; Farakka diversion; SalinitySource: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1432-0738Keywords: NO2 ; SO2 ; AHH, Benzo(a)pyreneSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Male Wistar rats were continuously exposed to NO2 (14.4 ppm), SO2 (46.5 ppm) and to a mixture of both gases and their effect on lung microsomal aryl hydrocarbon (benzo(a)pyrene) hydroxylase (AHH) activity was determined. The pre-exposed animals were administered methylcholanthrene (MC) to investigate the exposure effect on enzyme inducibility and pattern of B(a)P metabolites. NO2 significantly increased AHH activity but no marked change was noted with SO2. Induction of AHH by MC was markedly inhibited by SO2, only slightly by mixture of NO2-SO2 but not with NO2 alone.Type of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesWarrick, R. A. ; Kenny, G. J. ; Sims, G. C. ; Ericksen, N. J. ; Ahmad, Q. K. ; Mirza, M. Q.
Springer
Published 1996Staff ViewISSN: 1573-2932Keywords: New Zealand ; Bangladesh ; coastal resources ; water resources ; agroclimatic zones ; hydrology ; integrated model system ; BDCLIM ; CLIMPACTSSource: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringNotes: Abstract To examine the sensitivity of environmental systems to climatic variability and change, integrated model systems for climate impact assessment are being developed for New Zealand (CLIMPACTS) and Bangladesh (BDCLIM). Features common to both model systems include a global climate model, regional modules for generating climate scenarios, and models for biophysical impact analyses. For CLIMPACTS, modified ecosystem models for horticultural crops, arable crops, and pasture production are being incorporated. For BDCLIM, the emphasis is on analysis ofpossible changes in agroclimatic zones and hydrology, including the risks of floods and droughts. The initial emphasis of both systems is on nationwide spatial analyses, using simplified models as much as possible. The development of integrated model systems supports the needs of the respective countries in assessing scientific uncertainties, evaluating vulnerabilities, and identifying adaptation options as a basis for international reporting requirements under the U.N. Framework Convention on Climate Change and for policy and planning at national and regional levels. The major advantage of such integrated model systems is that they can readily be updated as the science of climate change advances, thus providing an evolving tool for future reassessments of climate impacts.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1573-4803Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract Notched tensile tests have been carried out on three common metals (pure iron, mild steel and aluminium alloy BS1474) over a wide range of strain-rates (10−3 to 104 s−1) and the strain-to-failure measured. The ductility of all three materials was found to be strongly dependent on the level of stress triaxiality in the specimen, this dependency being greatest for the ferrous materials and least for the aluminium alloy. No significant effect of strain-rate could be ascertained from the experimental results provided fracture remained fully ductile. However, for mild steel, a transition to a brittle fracture mode was observed for a given level of stress triaxiality as the strain-rate was increased. Numerical simulations of the experiments have been used to derive constants of a semi-empirical fracture model from the measured results. This model was found to give reasonable predictions of fracture over the range of conditions investigated.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1573-5036Keywords: actinorhizal plants ; nitrogen fixation ; oligonucleotide probes ; ribosomal RNASource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract Ecological studies on the actinomyceteFrankia are often influenced by the difficulty to isolate and identify this microorganism. The application of molecular biological techniques offers possibilities to detect microbes without isolation and cultivation.Nif genes or whole plasmids can serve as targets for the design of specific probes. Alternatively, ribosomal RNA (rRNA), commonly used in modern phylogenetic studies, can be used as a target molecule in ecological studies. This paper gives an overview of new developments on the use of 16S rRNA as a target molecule for oligonucleotide probes. Group-specific sequences in the 16S rRNA ofFrankia can be used as targets for oligonucleotide probes that a) recognize ineffectiveFrankia strains onAlnus, b) recognize effective strains onAlnus, c) recognize allFrankia strains tested so far. The present paper summarizes the essential steps needed for the use of these probes for the detection ofFrankia strains in soil without isolation and cultivation.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1573-5036Keywords: actinorhizal plants ; cross-inoculation ; Frankia ; nitrogen fixation ; PCR ; 16S rRNASource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Abstract Different Frankia strains and crushed nodule suspensions were tested for their ability to nodulate Coriaria nepalensis and Datisca cannabina. Datisca cannabina seedlings were nodulated effectively by both crushed nodule suspension from Coriaria nepalensis and Datisca cannabina. The origin of the endophyte in Datisca nodules induced by crushed nodules of Coriaria was confirmed by comparing partial PCR-amplified 16S rRNA sequences with those of the endophytes of both plants. Coriaria seedlings could only be nodulated by crushed nodule suspensions of Coriaria nepalensis. All pure cultures of Frankia used as a single inoculum source or in combinations with a nodule filtrate, failed to induce nodulation on Coriaria. Two atypical Frankia strains Cn3 and Cn7 isolated from Coriaria nodules showed no acetylene reduction activity and did not induce nodulation on the host seedlings.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 1573-2959Source: Springer Online Journal Archives 1860-2000Topics: Energy, Environment Protection, Nuclear Power EngineeringNotes: Abstract An atmospheric pollution survey was carried out at 13 sites in Karachi, Pakistan, simultaneously from 0600 h to 2100 h for 15 consecutive days in May 1990 which also included meteorological measurements. The monitoring sites were included along the prevailing wind patterns in Karachi. Carbon monoxide levels in the ambient air were found to reach 9–10 ppm along the busy urban streets whereas CO2 level exceeded 370 ppm in these areas. Our survey indicates that NO2 levels were exceeding U.S. ambient air quality standards. Maxmum NO2 concentrations were observed (0.3–0.5 ppm) during the daytime from 0600 h to 2100 h. The surface ozone maximum around noon at the inland sites reached the levels of 40 ppb and 50 ppb respectively compared to upwind coastal Sites 1 level of 25 ppb. The Pb concentrations were approximately 3- to 7-fold higher than average, which corresponded well to urban air. Fossil fuel SO4 (excess) and NO3 were apportionally based on the assumption that these two anions were present as (NH4)2SO4, and NH4NO3 in the aerosols. In the eastern part of the city atmospheric sulphate (SO4) shows the combustion of coal as its source from the vicinity and downwind of a steel manufacturing plant.Type of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesStaff View
ISSN: 1432-1955Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 1432-1955Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineType of Medium: Electronic ResourceURL: