ILSE | Search Results - (Author, Cooperation:M. Meyerson)

1

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

L. Bar-Peled ; L. Chantranupong ; A. D. Cherniack ; W. W. Chen ; K. A. Ottina ; B. C. Grabiner ; E. D. Spear ; S. L. Carter ; M. Meyerson ; D. M. Sabatini
American Association for the Advancement of Science (AAAS)
Published 2013

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Publication Date:	2013-06-01
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Amino Acids/metabolism ; Carrier Proteins/antagonists & inhibitors/genetics/metabolism ; Cell Line, Tumor ; GTPase-Activating Proteins ; HEK293 Cells ; Humans ; Lysosomes/enzymology ; Monomeric GTP-Binding Proteins/metabolism ; Multiprotein Complexes ; Mutation ; Neoplasms/enzymology/genetics ; Nuclear Proteins/antagonists & inhibitors/genetics/metabolism ; Proteins/metabolism ; RNA, Small Interfering/genetics ; TOR Serine-Threonine Kinases ; Tumor Suppressor Proteins/antagonists & inhibitors/genetics/*metabolism
Published by:	http://www.aaas.org/

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2

Recurrent hemizygous deletions in cancers may optimize proliferative potential

N. L. Solimini ; Q. Xu ; C. H. Mermel ; A. C. Liang ; M. R. Schlabach ; J. Luo ; A. E. Burrows ; A. N. Anselmo ; A. L. Bredemeyer ; M. Z. Li ; R. Beroukhim ; M. Meyerson ; S. J. Elledge
American Association for the Advancement of Science (AAAS)
Published 2012

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Publication Date:	2012-05-26
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Cell Line ; Cell Line, Tumor ; Cell Proliferation ; Cell Transformation, Neoplastic ; Chromosome Mapping ; Genes, Essential ; Genes, Neoplasm ; Genes, Recessive ; Genes, Tumor Suppressor ; Haploinsufficiency ; Hemizygote ; Humans ; Models, Genetic ; Neoplasms/genetics/pathology ; Oncogenes ; *Sequence Deletion
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

3

Landscape of genomic alterations in cervical carcinomas

A. I. Ojesina ; L. Lichtenstein ; S. S. Freeman ; C. S. Pedamallu ; I. Imaz-Rosshandler ; T. J. Pugh ; A. D. Cherniack ; L. Ambrogio ; K. Cibulskis ; B. Bertelsen ; S. Romero-Cordoba ; V. Trevino ; K. Vazquez-Santillan ; A. S. Guadarrama ; A. A. Wright ; M. W. Rosenberg ; F. Duke ; B. Kaplan ; R. Wang ; E. Nickerson ; H. M. Walline ; M. S. Lawrence ; C. Stewart ; S. L. Carter ; A. McKenna ; I. P. Rodriguez-Sanchez ; M. Espinosa-Castilla ; K. Woie ; L. Bjorge ; E. Wik ; M. K. Halle ; E. A. Hoivik ; C. Krakstad ; N. B. Gabino ; G. S. Gomez-Macias ; L. D. Valdez-Chapa ; M. L. Garza-Rodriguez ; G. Maytorena ; J. Vazquez ; C. Rodea ; A. Cravioto ; M. L. Cortes ; H. Greulich ; C. P. Crum ; D. S. Neuberg ; A. Hidalgo-Miranda ; C. R. Escareno ; L. A. Akslen ; T. E. Carey ; O. K. Vintermyr ; S. B. Gabriel ; H. A. Barrera-Saldana ; J. Melendez-Zajgla ; G. Getz ; H. B. Salvesen ; M. Meyerson
Nature Publishing Group (NPG)
Published 2014

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Publication Date:	2014-01-07
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Adenocarcinoma/genetics/virology ; Carcinoma, Squamous Cell/genetics/virology ; Case-Control Studies ; Cell Cycle Proteins/genetics ; Core Binding Factor beta Subunit/genetics ; DNA Copy Number Variations/genetics ; DNA Mutational Analysis ; DNA-Binding Proteins/genetics ; E1A-Associated p300 Protein/genetics ; Exome/genetics ; F-Box Proteins/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Genome, Human/genetics ; Genomics ; HLA-B Antigens/genetics ; Humans ; Mitogen-Activated Protein Kinase 1/genetics ; Mutation/genetics ; NF-E2-Related Factor 2/genetics ; Papillomaviridae/genetics/physiology ; Papillomavirus Infections/genetics ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins c-ets ; Receptor, ErbB-2/genetics ; Transcription Factors/genetics ; Transcriptome/genetics ; Tumor Suppressor Protein p53/genetics ; Ubiquitin-Protein Ligases/genetics ; Uterine Cervical Neoplasms/*genetics/virology ; Virus Integration/genetics
Published by:	http://www.nature.com/

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4

The genomic complexity of primary human prostate cancer

M. F. Berger ; M. S. Lawrence ; F. Demichelis ; Y. Drier ; K. Cibulskis ; A. Y. Sivachenko ; A. Sboner ; R. Esgueva ; D. Pflueger ; C. Sougnez ; R. Onofrio ; S. L. Carter ; K. Park ; L. Habegger ; L. Ambrogio ; T. Fennell ; M. Parkin ; G. Saksena ; D. Voet ; A. H. Ramos ; T. J. Pugh ; J. Wilkinson ; S. Fisher ; W. Winckler ; S. Mahan ; K. Ardlie ; J. Baldwin ; J. W. Simons ; N. Kitabayashi ; T. Y. MacDonald ; P. W. Kantoff ; L. Chin ; S. B. Gabriel ; M. B. Gerstein ; T. R. Golub ; M. Meyerson ; A. Tewari ; E. S. Lander ; G. Getz ; M. A. Rubin ; L. A. Garraway
Nature Publishing Group (NPG)
Published 2011

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Publication Date:	2011-02-11
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Carrier Proteins/genetics ; Case-Control Studies ; Cell Adhesion Molecules/genetics ; Chromatin/genetics/metabolism ; Chromosome Aberrations ; Chromosome Breakpoints ; Epigenesis, Genetic/genetics ; Gene Expression Regulation, Neoplastic ; Genome, Human/genetics ; Humans ; Male ; PTEN Phosphohydrolase/genetics/metabolism ; Prostatic Neoplasms/genetics ; Recombination, Genetic/genetics ; Signal Transduction/genetics ; Transcription, Genetic
Published by:	http://www.nature.com/

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5

Sequence analysis of mutations and translocations across breast cancer subtypes

S. Banerji ; K. Cibulskis ; C. Rangel-Escareno ; K. K. Brown ; S. L. Carter ; A. M. Frederick ; M. S. Lawrence ; A. Y. Sivachenko ; C. Sougnez ; L. Zou ; M. L. Cortes ; J. C. Fernandez-Lopez ; S. Peng ; K. G. Ardlie ; D. Auclair ; V. Bautista-Pina ; F. Duke ; J. Francis ; J. Jung ; A. Maffuz-Aziz ; R. C. Onofrio ; M. Parkin ; N. H. Pho ; V. Quintanar-Jurado ; A. H. Ramos ; R. Rebollar-Vega ; S. Rodriguez-Cuevas ; S. L. Romero-Cordoba ; S. E. Schumacher ; N. Stransky ; K. M. Thompson ; L. Uribe-Figueroa ; J. Baselga ; R. Beroukhim ; K. Polyak ; D. C. Sgroi ; A. L. Richardson ; G. Jimenez-Sanchez ; E. S. Lander ; S. B. Gabriel ; L. A. Garraway ; T. R. Golub ; J. Melendez-Zajgla ; A. Toker ; G. Getz ; A. Hidalgo-Miranda ; M. Meyerson
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-06-23
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Algorithms ; Breast Neoplasms/classification/genetics/pathology ; Core Binding Factor Alpha 2 Subunit/genetics ; Core Binding Factor beta Subunit/genetics ; DNA Mutational Analysis ; Exome/genetics ; Female ; Gene Fusion/genetics ; Humans ; Membrane Proteins/genetics ; Mexico ; Mutation/genetics ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors/genetics/metabolism ; Translocation, Genetic/genetics ; Vietnam
Published by:	http://www.nature.com/

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6

Melanoma genome sequencing reveals frequent PREX2 mutations

M. F. Berger ; E. Hodis ; T. P. Heffernan ; Y. L. Deribe ; M. S. Lawrence ; A. Protopopov ; E. Ivanova ; I. R. Watson ; E. Nickerson ; P. Ghosh ; H. Zhang ; R. Zeid ; X. Ren ; K. Cibulskis ; A. Y. Sivachenko ; N. Wagle ; A. Sucker ; C. Sougnez ; R. Onofrio ; L. Ambrogio ; D. Auclair ; T. Fennell ; S. L. Carter ; Y. Drier ; P. Stojanov ; M. A. Singer ; D. Voet ; R. Jing ; G. Saksena ; J. Barretina ; A. H. Ramos ; T. J. Pugh ; N. Stransky ; M. Parkin ; W. Winckler ; S. Mahan ; K. Ardlie ; J. Baldwin ; J. Wargo ; D. Schadendorf ; M. Meyerson ; S. B. Gabriel ; T. R. Golub ; S. N. Wagner ; E. S. Lander ; G. Getz ; L. Chin ; L. A. Garraway
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-05-25
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Chromosome Breakpoints/radiation effects ; DNA Damage ; DNA Mutational Analysis ; Gene Expression Regulation, Neoplastic ; Genome, Human/genetics ; Guanine Nucleotide Exchange Factors/genetics/metabolism ; Humans ; Melanocytes/metabolism/pathology ; Melanoma/genetics/pathology ; Mutagenesis/radiation effects ; Mutation/genetics/radiation effects ; Oncogenes/genetics ; Sunlight/*adverse effects ; Ultraviolet Rays/adverse effects
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

7

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

P. A. Northcott ; D. J. Shih ; J. Peacock ; L. Garzia ; A. S. Morrissy ; T. Zichner ; A. M. Stutz ; A. Korshunov ; J. Reimand ; S. E. Schumacher ; R. Beroukhim ; D. W. Ellison ; C. R. Marshall ; A. C. Lionel ; S. Mack ; A. Dubuc ; Y. Yao ; V. Ramaswamy ; B. Luu ; A. Rolider ; F. M. Cavalli ; X. Wang ; M. Remke ; X. Wu ; R. Y. Chiu ; A. Chu ; E. Chuah ; R. D. Corbett ; G. R. Hoad ; S. D. Jackman ; Y. Li ; A. Lo ; K. L. Mungall ; K. M. Nip ; J. Q. Qian ; A. G. Raymond ; N. T. Thiessen ; R. J. Varhol ; I. Birol ; R. A. Moore ; A. J. Mungall ; R. Holt ; D. Kawauchi ; M. F. Roussel ; M. Kool ; D. T. Jones ; H. Witt ; L. A. Fernandez ; A. M. Kenney ; R. J. Wechsler-Reya ; P. Dirks ; T. Aviv ; W. A. Grajkowska ; M. Perek-Polnik ; C. C. Haberler ; O. Delattre ; S. S. Reynaud ; F. F. Doz ; S. S. Pernet-Fattet ; B. K. Cho ; S. K. Kim ; K. C. Wang ; W. Scheurlen ; C. G. Eberhart ; M. Fevre-Montange ; A. Jouvet ; I. F. Pollack ; X. Fan ; K. M. Muraszko ; G. Y. Gillespie ; C. Di Rocco ; L. Massimi ; E. M. Michiels ; N. K. Kloosterhof ; P. J. French ; J. M. Kros ; J. M. Olson ; R. G. Ellenbogen ; K. Zitterbart ; L. Kren ; R. C. Thompson ; M. K. Cooper ; B. Lach ; R. E. McLendon ; D. D. Bigner ; A. Fontebasso ; S. Albrecht ; N. Jabado ; J. C. Lindsey ; S. Bailey ; N. Gupta ; W. A. Weiss ; L. Bognar ; A. Klekner ; T. E. Van Meter ; T. Kumabe ; T. Tominaga ; S. K. Elbabaa ; J. R. Leonard ; J. B. Rubin ; L. M. Liau ; E. G. Van Meir ; M. Fouladi ; H. Nakamura ; G. Cinalli ; M. Garami ; P. Hauser ; A. G. Saad ; A. Iolascon ; S. Jung ; C. G. Carlotti ; R. Vibhakar ; Y. S. Ra ; S. Robinson ; M. Zollo ; C. C. Faria ; J. A. Chan ; M. L. Levy ; P. H. Sorensen ; M. Meyerson ; S. L. Pomeroy ; Y. J. Cho ; G. D. Bader ; U. Tabori ; C. E. Hawkins ; E. Bouffet ; S. W. Scherer ; J. T. Rutka ; D. Malkin ; S. C. Clifford ; S. J. Jones ; J. O. Korbel ; S. M. Pfister ; M. A. Marra ; M. D. Taylor
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-07-27
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Carrier Proteins/genetics ; Cerebellar Neoplasms/classification/genetics/metabolism ; Child ; DNA Copy Number Variations/genetics ; Gene Duplication/genetics ; Genes, myc/genetics ; Genome, Human/genetics ; Genomic Structural Variation/genetics ; Genomics ; Hedgehog Proteins/metabolism ; Humans ; Medulloblastoma/classification/genetics/metabolism ; NF-kappa B/metabolism ; Nerve Tissue Proteins/genetics ; Oncogene Proteins, Fusion/genetics ; Proteins/genetics ; RNA, Long Noncoding ; Signal Transduction ; Transforming Growth Factor beta/metabolism ; Translocation, Genetic/genetics
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

8

Dissecting the genomic complexity underlying medulloblastoma

D. T. Jones ; N. Jager ; M. Kool ; T. Zichner ; B. Hutter ; M. Sultan ; Y. J. Cho ; T. J. Pugh ; V. Hovestadt ; A. M. Stutz ; T. Rausch ; H. J. Warnatz ; M. Ryzhova ; S. Bender ; D. Sturm ; S. Pleier ; H. Cin ; E. Pfaff ; L. Sieber ; A. Wittmann ; M. Remke ; H. Witt ; S. Hutter ; T. Tzaridis ; J. Weischenfeldt ; B. Raeder ; M. Avci ; V. Amstislavskiy ; M. Zapatka ; U. D. Weber ; Q. Wang ; B. Lasitschka ; C. C. Bartholomae ; M. Schmidt ; C. von Kalle ; V. Ast ; C. Lawerenz ; J. Eils ; R. Kabbe ; V. Benes ; P. van Sluis ; J. Koster ; R. Volckmann ; D. Shih ; M. J. Betts ; R. B. Russell ; S. Coco ; G. P. Tonini ; U. Schuller ; V. Hans ; N. Graf ; Y. J. Kim ; C. Monoranu ; W. Roggendorf ; A. Unterberg ; C. Herold-Mende ; T. Milde ; A. E. Kulozik ; A. von Deimling ; O. Witt ; E. Maass ; J. Rossler ; M. Ebinger ; M. U. Schuhmann ; M. C. Fruhwald ; M. Hasselblatt ; N. Jabado ; S. Rutkowski ; A. O. von Bueren ; D. Williamson ; S. C. Clifford ; M. G. McCabe ; V. P. Collins ; S. Wolf ; S. Wiemann ; H. Lehrach ; B. Brors ; W. Scheurlen ; J. Felsberg ; G. Reifenberger ; P. A. Northcott ; M. D. Taylor ; M. Meyerson ; S. L. Pomeroy ; M. L. Yaspo ; J. O. Korbel ; A. Korshunov ; R. Eils ; S. M. Pfister ; P. Lichter
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-07-27
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Aging/genetics ; Amino Acid Sequence ; Cell Transformation, Neoplastic ; Cerebellar Neoplasms/classification/diagnosis/genetics/pathology ; Child ; Chromatin/metabolism ; Chromosomes, Human/genetics ; DEAD-box RNA Helicases/genetics ; DNA Helicases/genetics ; DNA-Binding Proteins/genetics ; Genome, Human/genetics ; Genomics ; Hedgehog Proteins/metabolism ; High-Throughput Nucleotide Sequencing ; Histone Demethylases/genetics ; Humans ; Medulloblastoma/classification/diagnosis/*genetics/pathology ; Methylation ; Mutation/genetics ; Mutation Rate ; Neoplasm Proteins/genetics ; Nuclear Proteins/genetics ; Oncogene Proteins, Fusion/genetics ; Phosphoprotein Phosphatases/genetics ; Polyploidy ; Receptors, Cell Surface/genetics ; Sequence Analysis, RNA ; Signal Transduction ; T-Box Domain Proteins/genetics ; Transcription Factors/genetics ; Wnt Proteins/metabolism ; beta Catenin/genetics
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

9

Discovery and saturation analysis of cancer genes across 21 tumour types

M. S. Lawrence ; P. Stojanov ; C. H. Mermel ; J. T. Robinson ; L. A. Garraway ; T. R. Golub ; M. Meyerson ; S. B. Gabriel ; E. S. Lander ; G. Getz
Nature Publishing Group (NPG)
Published 2014

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Publication Date:	2014-01-07
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Apoptosis/genetics ; Case-Control Studies ; Cell Proliferation ; Chromatin/genetics ; DNA Mutational Analysis ; Exome/genetics ; Genes, Neoplasm/genetics ; Genome, Human/genetics ; Genomic Instability/genetics ; Genomics ; Humans ; Immune Evasion/genetics ; Mutation Rate ; Neoplasms/classification/*genetics/pathology ; Point Mutation/genetics ; RNA Processing, Post-Transcriptional/genetics ; Sample Size
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

10

Pugh et al. reply

T. J. Pugh ; S. Banerji ; M. Meyerson
Nature Publishing Group (NPG)
Published 2015

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Publication Date:	2015-04-17
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Breast Neoplasms/classification/genetics ; Female ; Humans ; Mutation/genetics ; Translocation, Genetic/genetics
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

11

The mutational landscape of head and neck squamous cell carcinoma

N. Stransky ; A. M. Egloff ; A. D. Tward ; A. D. Kostic ; K. Cibulskis ; A. Sivachenko ; G. V. Kryukov ; M. S. Lawrence ; C. Sougnez ; A. McKenna ; E. Shefler ; A. H. Ramos ; P. Stojanov ; S. L. Carter ; D. Voet ; M. L. Cortes ; D. Auclair ; M. F. Berger ; G. Saksena ; C. Guiducci ; R. C. Onofrio ; M. Parkin ; M. Romkes ; J. L. Weissfeld ; R. R. Seethala ; L. Wang ; C. Rangel-Escareno ; J. C. Fernandez-Lopez ; A. Hidalgo-Miranda ; J. Melendez-Zajgla ; W. Winckler ; K. Ardlie ; S. B. Gabriel ; M. Meyerson ; E. S. Lander ; G. Getz ; T. R. Golub ; L. A. Garraway ; J. R. Grandis
American Association for the Advancement of Science (AAAS)
Published 2011

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Publication Date:	2011-07-30
Publisher:	American Association for the Advancement of Science (AAAS)
Print ISSN:	0036-8075
Electronic ISSN:	1095-9203
Topics:	Biology Chemistry and Pharmacology Computer Science Medicine Natural Sciences in General Physics
Keywords:	Algorithms ; Apoptosis ; Carcinoma/genetics/metabolism/virology ; Carcinoma, Squamous Cell ; Cell Differentiation ; Exons ; Head and Neck Neoplasms/genetics/metabolism/virology ; Humans ; Mutation ; Neoplasms, Squamous Cell/genetics/metabolism/virology ; Papillomaviridae/isolation & purification ; Papillomavirus Infections/virology ; Point Mutation ; Receptor, Notch1/genetics/metabolism ; Sequence Analysis, DNA ; Sequence Deletion ; Signal Transduction ; Smoking ; Tobacco
Published by:	http://www.aaas.org/

Latest Papers from Table of Contents or Articles in Press

12

Chromothripsis from DNA damage in micronuclei

C. Z. Zhang ; A. Spektor ; H. Cornils ; J. M. Francis ; E. K. Jackson ; S. Liu ; M. Meyerson ; D. Pellman
Nature Publishing Group (NPG)
Published 2015

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Publication Date:	2015-05-29
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Cell Line ; Cell Survival ; Chromosome Breakage ; Chromosome Segregation/genetics ; DNA Copy Number Variations/genetics ; DNA Damage ; Gene Rearrangement/genetics ; Genomic Instability/genetics ; Humans ; *Micronuclei, Chromosome-Defective ; Mutation/genetics ; Neoplasms/genetics ; S Phase/genetics ; Single-Cell Analysis
Published by:	http://www.nature.com/

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13

Initial genome sequencing and analysis of multiple myeloma

M. A. Chapman ; M. S. Lawrence ; J. J. Keats ; K. Cibulskis ; C. Sougnez ; A. C. Schinzel ; C. L. Harview ; J. P. Brunet ; G. J. Ahmann ; M. Adli ; K. C. Anderson ; K. G. Ardlie ; D. Auclair ; A. Baker ; P. L. Bergsagel ; B. E. Bernstein ; Y. Drier ; R. Fonseca ; S. B. Gabriel ; C. C. Hofmeister ; S. Jagannath ; A. J. Jakubowiak ; A. Krishnan ; J. Levy ; T. Liefeld ; S. Lonial ; S. Mahan ; B. Mfuko ; S. Monti ; L. M. Perkins ; R. Onofrio ; T. J. Pugh ; S. V. Rajkumar ; A. H. Ramos ; D. S. Siegel ; A. Sivachenko ; A. K. Stewart ; S. Trudel ; R. Vij ; D. Voet ; W. Winckler ; T. Zimmerman ; J. Carpten ; J. Trent ; W. C. Hahn ; L. A. Garraway ; M. Meyerson ; E. S. Lander ; G. Getz ; T. R. Golub
Nature Publishing Group (NPG)
Published 2011

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Publication Date:	2011-03-25
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Amino Acid Sequence ; Blood Coagulation/genetics ; CpG Islands/genetics ; DNA Mutational Analysis ; DNA Repair/genetics ; Exons/genetics ; Exosome Multienzyme Ribonuclease Complex ; Genome, Human/genetics ; Genomics ; Histones/metabolism ; Homeodomain Proteins/genetics ; Homeostasis/genetics ; Humans ; Methylation ; Models, Molecular ; Molecular Sequence Data ; Multiple Myeloma/drug therapy/enzymology/genetics/metabolism ; Mutation/*genetics ; NF-kappa B/metabolism ; Oncogenes/genetics ; Open Reading Frames/genetics ; Protein Biosynthesis/genetics ; Protein Conformation ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors/genetics/metabolism ; RNA Processing, Post-Transcriptional/genetics ; Ribonucleases/chemistry/genetics ; Signal Transduction/genetics ; Transcription, Genetic/genetics
Published by:	http://www.nature.com/

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14

Suppression of lung adenocarcinoma progression by Nkx2-1

M. M. Winslow ; T. L. Dayton ; R. G. Verhaak ; C. Kim-Kiselak ; E. L. Snyder ; D. M. Feldser ; D. D. Hubbard ; M. J. DuPage ; C. A. Whittaker ; S. Hoersch ; S. Yoon ; D. Crowley ; R. T. Bronson ; D. Y. Chiang ; M. Meyerson ; T. Jacks
Nature Publishing Group (NPG)
Published 2011

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Publication Date:	2011-04-08
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Adenocarcinoma/genetics/physiopathology ; Animals ; Cell Differentiation ; Cell Line, Tumor ; Disease Models, Animal ; Down-Regulation ; Gene Expression Regulation, Neoplastic ; HMGA2 Protein/genetics ; Humans ; Lung Neoplasms/genetics/physiopathology ; Mice ; Nuclear Proteins/genetics/metabolism ; Transcription Factors/genetics/*metabolism
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

15

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

J. Barretina ; G. Caponigro ; N. Stransky ; K. Venkatesan ; A. A. Margolin ; S. Kim ; C. J. Wilson ; J. Lehar ; G. V. Kryukov ; D. Sonkin ; A. Reddy ; M. Liu ; L. Murray ; M. F. Berger ; J. E. Monahan ; P. Morais ; J. Meltzer ; A. Korejwa ; J. Jane-Valbuena ; F. A. Mapa ; J. Thibault ; E. Bric-Furlong ; P. Raman ; A. Shipway ; I. H. Engels ; J. Cheng ; G. K. Yu ; J. Yu ; P. Aspesi, Jr. ; M. de Silva ; K. Jagtap ; M. D. Jones ; L. Wang ; C. Hatton ; E. Palescandolo ; S. Gupta ; S. Mahan ; C. Sougnez ; R. C. Onofrio ; T. Liefeld ; L. MacConaill ; W. Winckler ; M. Reich ; N. Li ; J. P. Mesirov ; S. B. Gabriel ; G. Getz ; K. Ardlie ; V. Chan ; V. E. Myer ; B. L. Weber ; J. Porter ; M. Warmuth ; P. Finan ; J. L. Harris ; M. Meyerson ; T. R. Golub ; M. P. Morrissey ; W. R. Sellers ; R. Schlegel ; L. A. Garraway
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-03-31
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Cell Lineage ; Chromosomes, Human/genetics ; Clinical Trials as Topic/methods ; Databases, Factual ; Drug Screening Assays, Antitumor/methods ; Encyclopedias as Topic ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Genes, ras/genetics ; Genome, Human/genetics ; Genomics ; Humans ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors/metabolism ; Models, Biological ; Neoplasms/drug therapy/genetics/metabolism/pathology ; Pharmacogenetics ; Plasma Cells/cytology/drug effects/metabolism ; Precision Medicine/methods ; Receptor, IGF Type 1/antagonists & inhibitors/metabolism ; Receptors, Aryl Hydrocarbon/genetics/metabolism ; Sequence Analysis, DNA ; Topoisomerase Inhibitors/pharmacology
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

16

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

T. J. Pugh ; S. D. Weeraratne ; T. C. Archer ; D. A. Pomeranz Krummel ; D. Auclair ; J. Bochicchio ; M. O. Carneiro ; S. L. Carter ; K. Cibulskis ; R. L. Erlich ; H. Greulich ; M. S. Lawrence ; N. J. Lennon ; A. McKenna ; J. Meldrim ; A. H. Ramos ; M. G. Ross ; C. Russ ; E. Shefler ; A. Sivachenko ; B. Sogoloff ; P. Stojanov ; P. Tamayo ; J. P. Mesirov ; V. Amani ; N. Teider ; S. Sengupta ; J. P. Francois ; P. A. Northcott ; M. D. Taylor ; F. Yu ; G. R. Crabtree ; A. G. Kautzman ; S. B. Gabriel ; G. Getz ; N. Jager ; D. T. Jones ; P. Lichter ; S. M. Pfister ; T. M. Roberts ; M. Meyerson ; S. L. Pomeroy ; Y. J. Cho
Nature Publishing Group (NPG)
Published 2012

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Publication Date:	2012-07-24
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Cerebellar Neoplasms/classification/genetics ; Child ; DEAD-box RNA Helicases/chemistry/genetics/metabolism ; DNA Helicases/chemistry/genetics ; DNA-Binding Proteins/genetics ; Exome/genetics ; Genome, Human/genetics ; Hedgehog Proteins/metabolism ; Histone-Lysine N-Methyltransferase/genetics/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; LIM Domain Proteins/genetics ; Medulloblastoma/classification/genetics ; Models, Molecular ; Mutation/*genetics ; Neoplasm Proteins/genetics ; Nuclear Proteins/chemistry/genetics ; Promoter Regions, Genetic/genetics ; Protein Structure, Tertiary/genetics ; Proto-Oncogene Proteins/genetics ; Receptors, Cell Surface/genetics ; Repressor Proteins/genetics ; Signal Transduction ; TCF Transcription Factors/metabolism ; Transcription Factors/chemistry/genetics ; Tumor Suppressor Protein p53/genetics ; Wnt Proteins/metabolism ; beta Catenin/genetics/metabolism
Published by:	http://www.nature.com/

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17

Mutational heterogeneity in cancer and the search for new cancer-associated genes

M. S. Lawrence ; P. Stojanov ; P. Polak ; G. V. Kryukov ; K. Cibulskis ; A. Sivachenko ; S. L. Carter ; C. Stewart ; C. H. Mermel ; S. A. Roberts ; A. Kiezun ; P. S. Hammerman ; A. McKenna ; Y. Drier ; L. Zou ; A. H. Ramos ; T. J. Pugh ; N. Stransky ; E. Helman ; J. Kim ; C. Sougnez ; L. Ambrogio ; E. Nickerson ; E. Shefler ; M. L. Cortes ; D. Auclair ; G. Saksena ; D. Voet ; M. Noble ; D. DiCara ; P. Lin ; L. Lichtenstein ; D. I. Heiman ; T. Fennell ; M. Imielinski ; B. Hernandez ; E. Hodis ; S. Baca ; A. M. Dulak ; J. Lohr ; D. A. Landau ; C. J. Wu ; J. Melendez-Zajgla ; A. Hidalgo-Miranda ; A. Koren ; S. A. McCarroll ; J. Mora ; R. S. Lee ; B. Crompton ; R. Onofrio ; M. Parkin ; W. Winckler ; K. Ardlie ; S. B. Gabriel ; C. W. Roberts ; J. A. Biegel ; K. Stegmaier ; A. J. Bass ; L. A. Garraway ; M. Meyerson ; T. R. Golub ; D. A. Gordenin ; S. Sunyaev ; E. S. Lander ; G. Getz
Nature Publishing Group (NPG)
Published 2013

Staff View

Publication Date:	2013-06-19
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Artifacts ; DNA Replication Timing ; Exome/genetics ; False Positive Reactions ; Gene Expression ; Genetic Heterogeneity ; Genome, Human/genetics ; Humans ; Lung Neoplasms/genetics ; Mutation/genetics ; Mutation Rate ; Neoplasms/classification/genetics/pathology ; Neoplasms, Squamous Cell/genetics ; Oncogenes/genetics ; Reproducibility of Results ; Sample Size
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

18

Signatures of mutational processes in human cancer

L. B. Alexandrov ; S. Nik-Zainal ; D. C. Wedge ; S. A. Aparicio ; S. Behjati ; A. V. Biankin ; G. R. Bignell ; N. Bolli ; A. Borg ; A. L. Borresen-Dale ; S. Boyault ; B. Burkhardt ; A. P. Butler ; C. Caldas ; H. R. Davies ; C. Desmedt ; R. Eils ; J. E. Eyfjord ; J. A. Foekens ; M. Greaves ; F. Hosoda ; B. Hutter ; T. Ilicic ; S. Imbeaud ; M. Imielinski ; N. Jager ; D. T. Jones ; D. Jones ; S. Knappskog ; M. Kool ; S. R. Lakhani ; C. Lopez-Otin ; S. Martin ; N. C. Munshi ; H. Nakamura ; P. A. Northcott ; M. Pajic ; E. Papaemmanuil ; A. Paradiso ; J. V. Pearson ; X. S. Puente ; K. Raine ; M. Ramakrishna ; A. L. Richardson ; J. Richter ; P. Rosenstiel ; M. Schlesner ; T. N. Schumacher ; P. N. Span ; J. W. Teague ; Y. Totoki ; A. N. Tutt ; R. Valdes-Mas ; M. M. van Buuren ; L. van 't Veer ; A. Vincent-Salomon ; N. Waddell ; L. R. Yates ; J. Zucman-Rossi ; P. A. Futreal ; U. McDermott ; P. Lichter ; M. Meyerson ; S. M. Grimmond ; R. Siebert ; E. Campo ; T. Shibata ; S. M. Pfister ; P. J. Campbell ; M. R. Stratton
Nature Publishing Group (NPG)
Published 2013

Staff View

Publication Date:	2013-08-16
Publisher:	Nature Publishing Group (NPG)
Print ISSN:	0028-0836
Electronic ISSN:	1476-4687
Topics:	Biology Chemistry and Pharmacology Medicine Natural Sciences in General Physics
Keywords:	Aging/genetics ; Algorithms ; Cell Transformation, Neoplastic/genetics/pathology ; Cytidine Deaminase/genetics ; DNA/genetics/metabolism ; DNA Mutational Analysis ; Humans ; Models, Genetic ; Mutagenesis/genetics ; Mutagenesis, Insertional/genetics ; Mutagens/pharmacology ; Mutation/genetics ; Neoplasms/enzymology/genetics/pathology ; Organ Specificity ; Reproducibility of Results ; Sequence Deletion/genetics ; Transcription, Genetic/genetics
Published by:	http://www.nature.com/

Latest Papers from Table of Contents or Articles in Press

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