Search Results - (Author, Cooperation:M. McMahon)
-
1Latest Papers from Table of Contents or Articles in PressN. Tang ; W. F. Marshall ; M. McMahon ; R. J. Metzger ; G. R. Martin
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-07-19Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing ; Animals ; Cell Polarity ; Cell Proliferation ; Cell Shape ; Cell Size ; Epithelial Cells/cytology ; Fibroblast Growth Factor 10/genetics/metabolism ; Intracellular Signaling Peptides and Proteins ; Lung/cytology/*embryology/metabolism ; *MAP Kinase Signaling System ; Membrane Proteins/genetics/metabolism ; Mice ; Mice, Knockout ; Mitogen-Activated Protein Kinase 1/*metabolism ; Mitogen-Activated Protein Kinase 3/*metabolism ; Mitosis ; Models, Biological ; *Morphogenesis ; Mutation ; Organogenesis ; Phosphoproteins/genetics/metabolism ; Phosphorylation ; Proto-Oncogene Proteins p21(ras)/genetics/*metabolism ; Respiratory Mucosa/cytology/*embryology ; Spindle Apparatus/*physiology/ultrastructurePublished by: -
2Latest Papers from Table of Contents or Articles in PressM. J. Sanderson ; M. M. McMahon ; M. Steel
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-06-18Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Algorithms ; Angiosperms/*classification/genetics ; Animals ; Arthropods/*classification/genetics ; Bayes Theorem ; Biological Evolution ; Colubridae/*classification/genetics ; Data Interpretation, Statistical ; Genomics/methods ; Likelihood Functions ; *Models, Statistical ; *Phylogeny ; Poaceae/classification/genetics ; Sequence AlignmentPublished by: -
3Latest Papers from Table of Contents or Articles in PressRapport, F., Bierbaum, M., McMahon, C., Boisvert, I., Lau, A., Braithwaite, J., Hughes, S.
BMJ Publishing
Published 2018Staff ViewPublication Date: 2018-05-30Publisher: BMJ PublishingElectronic ISSN: 2044-6055Topics: MedicineKeywords: Open access, Qualitative researchPublished by: -
4Latest Papers from Table of Contents or Articles in PressM. Das Thakur ; F. Salangsang ; A. S. Landman ; W. R. Sellers ; N. K. Pryer ; M. P. Levesque ; R. Dummer ; M. McMahon ; D. D. Stuart
Nature Publishing Group (NPG)
Published 2013Staff ViewPublication Date: 2013-01-11Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Disease Models, Animal ; Drug Administration Schedule ; Drug Resistance, Neoplasm/*drug effects ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Indoles/*administration & dosage/*adverse effects/pharmacology ; MAP Kinase Signaling System/drug effects ; Melanoma/*drug therapy/genetics/*pathology ; Mice ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Mutation ; Neoplasm Transplantation ; Proto-Oncogene Proteins B-raf/chemistry/genetics/metabolism ; Subcutaneous Tissue ; Sulfonamides/*administration & dosage/*adverse effects/pharmacology ; Time Factors ; Xenograft Model Antitumor AssaysPublished by: -
5Latest Papers from Table of Contents or Articles in PressStaff View
Publication Date: 2014-05-23Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Transformation, Neoplastic/*metabolism ; Histone-Lysine N-Methyltransferase/*metabolism ; Humans ; Lysine/*metabolism ; MAP Kinase Kinase Kinase 2/*metabolism ; MAP Kinase Kinase Kinases/*metabolism ; Oncogene Protein p21(ras)/*metabolismPublished by: -
6Latest Papers from Table of Contents or Articles in PressD. Mitra ; X. Luo ; A. Morgan ; J. Wang ; M. P. Hoang ; J. Lo ; C. R. Guerrero ; J. K. Lennerz ; M. C. Mihm ; J. A. Wargo ; K. C. Robinson ; S. P. Devi ; J. C. Vanover ; J. A. D'Orazio ; M. McMahon ; M. W. Bosenberg ; K. M. Haigis ; D. A. Haber ; Y. Wang ; D. E. Fisher
Nature Publishing Group (NPG)
Published 2012Staff ViewPublication Date: 2012-11-06Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Gene Expression Regulation/drug effects ; Hair Color/*genetics ; Indoles/pharmacology ; Melanins/metabolism ; Melanoma/*genetics ; Mice ; Mice, Inbred C57BL ; Monophenol Monooxygenase/genetics ; Peroxidases/metabolism ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins B-raf/genetics ; Receptor, Melanocortin, Type 1/genetics ; Skin Pigmentation/*genetics ; Sulfonamides/pharmacology ; Survival Analysis ; Tumor Cells, Cultured ; *Ultraviolet RaysPublished by: -
7Latest Papers from Table of Contents or Articles in PressJ. T. Kulongoski, P. B. McMahon, M. T. Land, M. T. Wright, T. A. Johnson, M. K. Landon
Wiley-Blackwell
Published 2018Staff ViewPublication Date: 2018-02-13Publisher: Wiley-BlackwellPrint ISSN: 0148-0227Topics: BiologyGeosciencesPublished by: -
8Articles: DFG German National LicensesNelmes, R. J. ; Hatton, P. D. ; McMahon, M. I. ; Piltz, R. O. ; Crain, J. ; Cernik, R. J. ; Bushnell-Wye, G.
[S.l.] : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: An imaging-plate system designed for the full Rietveld refinement of crystal structures at high pressure is described. Emphasis is given to techniques that have been developed to obtain data free from contaminating diffraction peaks. Initial results from studies of III–V semiconductors and La2CuO4 are given.Type of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesPiltz, R. O. ; McMahon, M. I. ; Crain, J. ; Hatton, P. D. ; Nelmes, R. J. ; Cernik, R. J. ; Bushnell-Wye, G.
[S.l.] : American Institute of Physics (AIP)
Published 1992Staff ViewISSN: 1089-7623Source: AIP Digital ArchiveTopics: PhysicsElectrical Engineering, Measurement and Control TechnologyNotes: The use of an imaging plate as a two-dimensional (2-D) detector removes many of the difficulties that arise in performing angle-dispersive powder diffraction at high pressures in a diamond-anvil cell. Due to the 2-D nature of the imaging plate, a substantial part of each Debye Scherrer ring is intercepted and recorded. The averaging of the intensities around a ring so as to create a conventional one-dimensional (1-D) powder pattern results in a significant improvement in counting statistics and powder averaging, both severe problems in high-pressure diffraction due to the very small sample volumes involved. For an accurately known plate geometry the 2-D to 1-D conversion is straightforward; however, considerable complications arise when inaccuracies in plate to sample distance, plate orientations, poor powder averaging/preferred orientation, and the presence of diamond Bragg spots are considered. The current status of the software used to analyze the imaging plate data is presented along with test data to illustrate its use.Type of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0017-789XTopics: General, InterdisciplinaryURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0017-789XTopics: General, InterdisciplinaryURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0014-4983Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: HistoryEconomicsType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0022-328XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 0022-328XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 0027-5107Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 0306-4603Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: MedicinePsychologyType of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1434-6036Keywords: 36.40.+d ; 33.70.Jg ; 67.40.YvSource: Springer Online Journal Archives 1860-2000Topics: PhysicsNotes: Abstract We examine the effects of impurities (“doping”) and rotational excitation on the structural and energetic properties of helium clusters. Quantum Monte Carlo (QMC) techniques are used to study ground and rotationally excited states of pure and doped clusters. We use exponentially correlated wave functions and treat the molecular impurities as rigid. Whereas pure HeN show essentially monotonic decay of density from a central maximum value, addition of impurities induces local ordering of He to an extent dependent on the impurity-He binding. Rotational excitation of HeN gives rise to extremely large centrifugal distortions. The location of impurities also appears to change upon rotational excitation. The implications of these distortions on impurity spectra are discussed for SF6HeN, and compared to recent experimental results.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 0925-4994Topics: LawURL: -
19Articles: DFG German National LicensesMcMahon, M. I. ; Nelmes, R. J. ; Kuhst, W. F. ; Dorwarth, R. ; Piltz, R. O. ; Tun, Z.
[s.l.] : Nature Publishing Group
Published 1990Staff ViewISSN: 1476-4687Source: Nature Archives 1869 - 2009Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsNotes: [Auszug] KH2PO4 (KDP) undergoes an H-ordering phase transition to a ferroelectric phase on cooling through Tc= 122 K at atmospheric pressure. Above Tc, the H atoms are 50:50 disordered over two sites, 8 apart, in short O-H-O bonds of length 2R linking the PO4 tetrahedra. Below Tc, the H atoms order fully ...Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesScott, M. G. ; Deering, A. H. ; McMahon, M. T. ; Harron, D. W. G. ; Shanks, R. G.
Springer
Published 1989Staff ViewISSN: 1432-1041Keywords: alfuzosin ; prazosin ; alpha1-adrenoceptor antagonist ; noradrenaline ; pharmacokinetics ; pharmacodynamics ; healthy volunteersSource: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyMedicineNotes: Summary In an open dose ranging study with random inclusion of placebo, alfuzosin (α1-adrenoceptor antagonist) 1, 2.5 and 5 mg was administered to 6 healthy volunteers, 3 of the volunteers received 10 mg alfuzosin. Supine systolic blood (SBP) pressure was not reduced by alfuzosin although significant increases occurred in supine heart rate (HR) after 2.5 and 5 mg. In the standing position, SBP was reduced at 2 and 4 h with 5 mg alfuzosin; significant increases in HR occurred following 1, 2.5 and 5 mg at 2, 4, 6 and 8 h after administration. Exercise SBP was not reduced; diastolic blood pressure was significantly reduced at 4 and 6 h with 5 mg alfuzosin. More marked effects were seen in the 3 subjects who received 10 mg alfuzosin. After 1 and 5 mg, tmax ranged from 1–2 h; Cmax (4.1 to 20.8 ng · ml−1; AUC (0–24) 20 to 132 ng · ml−1 · h (1 and 5 mg respectively) increased progressively with dose indicating dose dependent kinetics; no significant changes occurred in the visual analogue scale for sedation. A comparison of alfuzosin 5 mg, prazosin 1 mg and placebo each administered for 4 days, indicated that alfuzosin did not significantly reduce standing SBP on either Day 1 or Day 4; prazosin reduced SBP at 2 and 4 h on Day 1 and 6 h on Day 4 compared to placebo. Standing HR was increased by alfuzosin at 2 h on Day 1 and Day 4; increases occurred with prazosin at 2, 4, 6 and 8 h on Day 1 and 6 h on Day 4. Supine plasma noradrenaline increased with alfuzosin and prazosin at 2 and 4 h on Days 1 and 4; the increases were not significantly different. The plasma elimination half-life (t1/2) for alfuzosin was 3.4 h and 3.1 h after acute and chronic administration; (t1/2) for prazosin was 2.6 and 2.9 h. In conclusion alfuzosin causes small reductions in systolic blood pressure, accompanied by a dose dependent increase in heart rate in the supine and standing position and following exercise.Type of Medium: Electronic ResourceURL: