Search Results - (Author, Cooperation:M. Mahajan)
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1M. Fromer ; A. J. Pocklington ; D. H. Kavanagh ; H. J. Williams ; S. Dwyer ; P. Gormley ; L. Georgieva ; E. Rees ; P. Palta ; D. M. Ruderfer ; N. Carrera ; I. Humphreys ; J. S. Johnson ; P. Roussos ; D. D. Barker ; E. Banks ; V. Milanova ; S. G. Grant ; E. Hannon ; S. A. Rose ; K. Chambert ; M. Mahajan ; E. M. Scolnick ; J. L. Moran ; G. Kirov ; A. Palotie ; S. A. McCarroll ; P. Holmans ; P. Sklar ; M. J. Owen ; S. M. Purcell ; M. C. O'Donovan
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-01-28Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Child Development Disorders, Pervasive/genetics ; Cytoskeletal Proteins/metabolism ; Exome/genetics ; Fragile X Mental Retardation Protein/metabolism ; Humans ; Intellectual Disability/genetics ; *Models, Neurological ; Mutation/*genetics ; Mutation Rate ; Nerve Net/*metabolism/physiopathology ; Nerve Tissue Proteins/metabolism ; Neural Pathways/*metabolism/physiopathology ; Phenotype ; RNA, Messenger/genetics/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Schizophrenia/*genetics/metabolism/*physiopathology ; Substrate Specificity ; Synapses/*metabolismPublished by: -
2Staff View
ISSN: 0022-1902Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringType of Medium: Electronic ResourceURL: -
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ISSN: 0038-1098Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
6Staff View
ISSN: 1420-9071Keywords: Zinc ; obesitySource: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Abstract The body weight or body weight/height ratio exhibits a positive linear correlation to hair zinc (Zn) concentration which is more strongly positive in men than in women. The obese of both sexes possess higher Zn concentrations in their hair than those with normal body weight/height. The degree of obesity increases with the increase in the hair Zn concentration.Type of Medium: Electronic ResourceURL: -
7Staff View
ISSN: 1432-072XKeywords: Key wordsPseudomonas ; 1-Naphthoic acid ; Hydrocarbon degradation ; Hydroxylation ; Ring ; cleavageSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract Pseudomonas maltophilia CSV89, a bacterium isolated from soil in our laboratory, grows on 1-naphthoic acid as the sole source of carbon and energy. To elucidate the pathway for degradation of 1-naphthoic acid, the metabolites were isolated from spent medium, purified by TLC, and characterized by gas chromatography-mass spectrometry. The involvement of various metabolites as intermediates in the pathway was established by demonstrating relevant enzyme activities in cell-free extracts, oxygen uptake and transformation of metabolites by the whole cells. The results obtained from such studies suggest that the degradation of 1-naphthoic acid is initiated by double hydroxylation of the aromatic ring adjacent to the one bearing the carboxyl group, resulting in the formation of 1,2-dihydroxy-8-carboxynaphthalene. The resultant diol was oxidized via 3-formyl salicylate, 2-hydroxyisophthalate, salicylate and catechol to TCA cycle intermediates.Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 1432-072XKeywords: Key words:Pseudomonas– Methylnaphthalenes – Metabolism – Hydroxylation – Oxygenases – Aromatic ring cleavageSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract. Pseudomonas putida CSV86, a soil bacterium, grows on 1- and 2-methylnaphthalene as the sole source of carbon and energy. In order to deduce the pathways for the biodegradation of 1- and 2-methylnaphthalene, metabolites were isolated from the spent medium and purified by thin layer chromatography. Emphasis has been placed on the structural characterisation of isolated intermediates by GC-MS, demonstration of enzyme activities in the cell free extracts and measurement of oxygen uptake by whole cells in the presence of various probable metabolic intermediates. The data obtained from such a study suggest the possibility of occurrence of multiple pathways in the degradation of 1- and 2-methylnaphthalene. We propose that, in one of the pathways, the aromatic ring adjacent to the one bearing the methyl moiety is oxidized leading to the formation of methylsalicylates and methylcatechols. In another pathway the methyl side chain is hydroxylated to –CH2-OH which is further converted to –CHO and –COOH resulting in the formation of naphthoic acid as the end product. In addition to this, 2-hydroxymethylnaphthalene formed by the hydroxylation of the methyl group of 2-methylnaphthalene undergoes aromatic ring hydroxylation. The resultant dihydrodiol is further oxidised by a series of enzyme catalysed reactions to form 4-hydroxymethyl catechol as the end product of the pathway.Type of Medium: Electronic ResourceURL: -
9Staff View
ISSN: 1573-4803Source: Springer Online Journal Archives 1860-2000Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision MechanicsNotes: Abstract Ultra-thin (about 15 Å) initial deposits of Bi, Cu, Ag, Sn, Pb, Au and In-Bi solder have been used for subsequent deposition of the GaSb films by a flash evaporation technique. TEM studies reveal that the deposits stimulate grain growth in the films to different extents, with Au giving the best results. Also, the increase in the Au stimulator deposit thickness substantially increased the grain size. The electrical measurements made on the GaSb films grown with or without Au stimulators (below 30 Å) reveal that considerable improvement in the film properties can be obtained by using the stimulator.Type of Medium: Electronic ResourceURL: -
10Mahajan, M. A. ; Prasad, M. V. R. ; Mhatre, H. R. ; Sawant, R. M. ; Rastogi, R. K. ; Rizvi, G. H. ; Chaudhuri, N. K.
Springer
Published 1991Staff ViewISSN: 1588-2780Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringNotes: Abstract A quartz pyrohydrolysis apparatus designed for the safe handling of pyrophoric carbide nuclear fuel samples while separating C1 and F trace impurities for quality control analysis is described. It has several advantages over the commonly used pyrohydrolysis apparatus. Performance of the apparatus during routine analysis of a large number of nuclear fuel samples has been found to be quite satisfactory.Type of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 1588-2780Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringNotes: Abstract Stability constants of the fluoride complexes of Pu(III), Sm(III) and Bi(III) in 1.0M NaClO4/HClO4 medium at 23±1°C have been determined by potentiometry using a fluoride ion-selective electrode. Plutonium was reduced to the trivalent state using quinhydrone with an excess to serve as holding reductant. The log values of concentration stability constants log β1, log β2, and log β3 are 3.58, 6.40 and 12.61 for Pu(III), 3.23, 5.81 and 10.54 for Sm(III) and 3.69, 6.13 and 11.04 for Bi(III), respectively. The log β2 values in all these cases have very large deviation and may be taken only as rough estimates.Type of Medium: Electronic ResourceURL: -
12Determination of fluoride by spectrophotometry of Arsenazo(III) complex of the back-extracted Th(IV)Staff View
ISSN: 1588-2780Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringNotes: Abstract A method based on the back-extraction of Th(IV) from its TTA complex in benzene by aqueous F− followed by spectrophotometric measurement of Th(IV), for the determination of fluoride has been developed. The coefficients of variation obtained are 2.4% and 1.4% in 11 determinations at F− concentration levels of 1.0 μg ml−1, respectively.Type of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 1588-2780Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyEnergy, Environment Protection, Nuclear Power EngineeringNotes: Abstract Determination of fluoride at trace level is important for the specification analysis of nuclear fuel samples. This is generally accomplished by pyrohydrolytic separation followed by ion selective electrode potentiometry. In the present work, a method has been developed for the determination of fluoride by radiometric assay of181Hf back-extracted from thenoyltrifluoracetone (HTTA) in benzene.181Hf back-extracted is proportional to the concentration of fluoride.Type of Medium: Electronic ResourceURL: -
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ISSN: 0044-8249Keywords: Chemistry ; General ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyAdditional Material: 1 Tab.Type of Medium: Electronic ResourceURL: -
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ISSN: 0570-0833Keywords: Chemistry ; General ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyAdditional Material: 1 Tab.Type of Medium: Electronic ResourceURL: