Search Results - (Author, Cooperation:M. Line)

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  1. 1
    B. Macintosh ; J. R. Graham ; T. Barman ; R. J. De Rosa ; Q. Konopacky ; M. S. Marley ; C. Marois ; E. L. Nielsen ; L. Pueyo ; A. Rajan ; J. Rameau ; D. Saumon ; J. J. Wang ; J. Patience ; M. Ammons ; P. Arriaga ; E. Artigau ; S. Beckwith ; J. Brewster ; S. Bruzzone ; J. Bulger ; B. Burningham ; A. S. Burrows ; C. Chen ; E. Chiang ; J. K. Chilcote ; R. I. Dawson ; R. Dong ; R. Doyon ; Z. H. Draper ; G. Duchene ; T. M. Esposito ; D. Fabrycky ; M. P. Fitzgerald ; K. B. Follette ; J. J. Fortney ; B. Gerard ; S. Goodsell ; A. Z. Greenbaum ; P. Hibon ; S. Hinkley ; T. H. Cotten ; L. W. Hung ; P. Ingraham ; M. Johnson-Groh ; P. Kalas ; D. Lafreniere ; J. E. Larkin ; J. Lee ; M. Line ; D. Long ; J. Maire ; F. Marchis ; B. C. Matthews ; C. E. Max ; S. Metchev ; M. A. Millar-Blanchaer ; T. Mittal ; C. V. Morley ; K. M. Morzinski ; R. Murray-Clay ; R. Oppenheimer ; D. W. Palmer ; R. Patel ; M. D. Perrin ; L. A. Poyneer ; R. R. Rafikov ; F. T. Rantakyro ; E. L. Rice ; P. Rojo ; A. R. Rudy ; J. B. Ruffio ; M. T. Ruiz ; N. Sadakuni ; L. Saddlemyer ; M. Salama ; D. Savransky ; A. C. Schneider ; A. Sivaramakrishnan ; I. Song ; R. Soummer ; S. Thomas ; G. Vasisht ; J. K. Wallace ; K. Ward-Duong ; S. J. Wiktorowicz ; S. G. Wolff ; B. Zuckerman
    American Association for the Advancement of Science (AAAS)
    Published 2015
    Staff View
    Publication Date:
    2015-08-15
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
  3. 3
    MILLARD, M. M. ; VEISZ, O. B. ; KRIZEK, D. T. ; LINE, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1996
    Staff View
    ISSN:
    1365-3040
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    Multi-proton spin-echo images were collected from cold-acclimated winter wheat crowns (Triticum aestivum L.) cv. Cappelle Desprez at 400 MHz between 4 and −4 °C. Water proton relaxation by the spin-spin (T2) mechanism from individual voxels in image slices was found to be mono-exponential. The temperature dependence of these relaxation rates was found to obey Arrhenius or absolute rate theory expressions relating temperature, activation energies and relaxation rates, Images whose contrast is proportional to the Arrhenius activation energy (Ea), Gibb's free energy of activation (ΔG
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  4. 4
    MILLARD, M. M. ; VEISZ, O. B. ; KRIZEK, D. T. ; LINE, M.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1365-3040
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    Nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) were used to analyse changes in the physical state of water in wheat crowns during cold acclimation and during the freezing/thawing cycle. Spectroscopically measured average spin-spin relaxation times (T2) decreased during cold acclimation and increased when plants were grown at normal temperature. Spin-spin relaxation images whose contrast is proportional to T2, times were calculated allowing association of water relaxation with regions of tissue in spin-echo images during acclimation and freezing. Images taken during freezing revealed nonuniform freezing of tissue in crowns and roots. Acclimated and non-acclimated wheat crowns were imaged during freezing and after thawing. Spin-echo image signal intensity and T2 times decreased dramatically between -4°C and -8°C as a result of a decrease in water mobility during freezing. Images collected during thawing were diffuse with less structure and relaxation times were longer, consistent with water redistribution in tissue after membrane damage.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  5. 5
    Staff View
    ISSN:
    1460-9568
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Glutamine is involved in a variety of metabolic processes, including recycling of the neurotransmitters glutamate and γ-aminobutyric acid (GABA). The system N transporter SN1 mediates efflux as well as influx of glutamine in glial cells [Chaudhry et al. (1999), Cell, 99, 769–780]. We here report qualitative and quantitative data on SN1 protein expression in rat. The total tissue concentrations of SN1 in brain and in kidney are half and one-quarter, respectively, of that in liver, but the average concentration of SN1 could be higher in astrocytes than in hepatocytes. Light and electron microscopic immunocytochemistry shows that glutamatergic, GABAergic and, surprisingly, purely glycinergic boutons are ensheathed by astrocytic SN1 laden processes, indicating a role of glutamine in the production of all three rapid transmitters. A dedication of SN1 to neurotransmitter recycling is further supported by the lack of SN1 immunoreactivity in oligodendrocytes (cells rich in glutamine but without perisynaptic processes). All neuronal structures appear unlabelled implying that a different protein mediates glutamine uptake into nerve endings. In several regions, SN1 immunoreactivity is higher in association with GABAergic than glutamatergic synapses, in agreement with observations that exogenous glutamine increases output of transmitter glutamate but not GABA. Nerve terminals with low transmitter reuptake or high prevailing firing frequency are associated with high SN1 immunoreactivity in adjacent glia. Bergmann glia and certain other astroglia contain very low levels of SN1 immunoreactivity compared to most astroglia, including retinal Müller cells, indicating the possible existence of SN isoforms and alternative mechanisms for transmitter recycling.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  6. 6
    Bestwick, Lara A. ; Grønning, Line M. ; James, David C. ; Bones, Atle ; Rossiter, John T.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1993
    Staff View
    ISSN:
    1399-3054
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Notes:
    In germinating seedlings of Brassica napus glucosinolate levels decrease and are potentially degraded to nitriles by a myrosinase. Little is known about the metabolism of glucosinolate aglycone products and the objective of this work was to investigate nitrilase activity and carry out a purification of the enzyme from seedlings of B. napus. A nitrilase capable of converting phenylpropionitrile to phenylpropionic acid was purified to apparent homogeneity from seedlings of B. napus. The protein has a molecular mass of approximately 420 kDa made up of 38 kDa subunits. The pI of the native protein was found to be 4.6. Under denaturing conditions on an isoelectric focusing (IEF) gel a major and minor protein was observed with pI in the range of 5.4-5.9, suggesting the presence of isoforms. Apart from the potential role of the nitrilase in indole-3-acetic acid (IAA) synthesis a developmental study with seedlings indicates that the increase in activity observed may be linked to the in vivo degradation of glucosinolates.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    1573-7284
    Keywords:
    Bone mineral density ; Fractures ; Older women ; Osteoporosis ; Risk factors
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Abstract The objectives of this study were to determine factors related to fractures and bone mineral density (BMD) in a large group of Norwegian women. In a cross-sectional study, 3803 women aged 50–75, all with a history of fractures, were included in the study. BMD was measured with Dual energy X-ray absorptiometry at both hip (neck) and spine (L1–L4), while information on other factors thought to influence BMD were obtained through a questionnaire. In multivariate analysis, the strongest positive predictor of both hip and spine BMD was current body weight, while weight loss since the age of 25 and number of years since menopause were the strongest inverse predictors. In addition, use of cortisone and maternal history of fractures were associated with lower BMD, as was loss of height since the age of 25. Physical activity was positively correlated with BMD. These results show the complexity of factors involved in the etiology of osteoporosis, with several factors acting in synergism. This points to the need for multifactorial prevention strategies, which most effectively need to be instituted at an early age, before peak bone mass is achieved.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  8. 8
    Line, M. A.
    Springer
    Published 1990
    Staff View
    ISSN:
    1573-5036
    Keywords:
    endophytes ; enterobacteria ; N2-fixation
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes:
    Abstract Nitrogen-fixing enterobacteria (Enterobacter agglomerans and Citrobacter freundii) were commonly found associated with the microflora of stained Sassafras (Atherosperma moschatum Labill.) in forests of SE Tasmania. However, their populations never exceeded 3× 104 cells g−1 dry wood and comprised at most 3% of the total bacterial flora. Bacterial colonization of the wood appeared to coincide with that by non-hymenocetous fungi: bacteria were never isolated in significant numbers from wood not infected with fungi. The contribution of the N2-fixing flora to the N economy of the habitat is considered to be negligible.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  9. 9
    Archibald, G. ; Line, M. B.
    Springer
    Published 1991
    Staff View
    ISSN:
    1588-2861
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Information Science and Librarianship
    Nature of Science, Research, Systems of Higher Education, Museum Science
    Notes:
    Abstract It is commonly stated and believed that scholarly and scientific journal literature is growing exponentially. To obtain a truer picture of the situation, a study was made of a sample of 190 journals that started life in or before 1950, 20 in each of 9 subject fields, plus 10 extra in literature. The number of articles in each journal in 1950, 1960, 1970, 1980 and 1987 was counted. The analysis showed a rapid growth in most subjects up to 1970, a much slower growth between 1976 and 1980, and a slow growth or decline between 1980 and 1987; the fields of decline included general and physical science and technology. The total number of journals is still increasing, but the rate of growth has dropped dramatically over the last ten years. Although it is possible that more recently established journals would show a different pattern, it seems likely that the overall rate of growth of the total number of journal articles is slow.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  10. 10
    Line, M. B.
    Springer
    Published 1987
    Staff View
    ISSN:
    1588-2861
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Information Science and Librarianship
    Nature of Science, Research, Systems of Higher Education, Museum Science
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  11. 11
    Line, M. B.
    Springer
    Published 1987
    Staff View
    ISSN:
    1588-2861
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Information Science and Librarianship
    Nature of Science, Research, Systems of Higher Education, Museum Science
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  12. 12
    Line, M. J. ; Pritchard, R. G. ; Pynenburg, R. ; Latham, R. J. ; Linford, R. G.

    Chichester [u.a.] : Wiley-Blackwell
    Published 1995
    Staff View
    ISSN:
    0142-2421
    Keywords:
    Chemistry ; Polymer and Materials Science
    Source:
    Wiley InterScience Backfile Collection 1832-2000
    Topics:
    Physics
    Notes:
    Inelastic electron tunneling spectroscopy is used to compare the adsorption onto aluminium oxide of poly(ethylene glycol) of relative molar mass 400 (PEG400) with poly(ethylene glycol) that has been coordinated with zinc chloride. This work carried out on a low-molecular-weight analogue of a polymer electrolyte reveals that the steric hinderance brought about by the coordination of zinc chloride with poly(ethylene glycol) changes the mechanism by which the polymer bonds to an aluminium oxide surface. The zinc bonds both to atmospheric water and to the ether oxygens in the polymer, which restricts the conformational freedom of the polymer. This restriction causes the attachment of the polymer to the aluminium oxide substrate to be primarily by hydrogen bonding, which reveals itself through the appearance of an extra peak in the inelastic electron tunneling spectrum at ∼440 meV. The implication is that when monolayer coatings of PEG400/ZnCl2 are adsorbed on aluminium oxide, the coordination of the zinc with the polymer imposes a structure upon the latter.
    Additional Material:
    3 Ill.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses