Search Results - (Author, Cooperation:M. Langlois)
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1Latest Papers from Table of Contents or Articles in PressA. Boccaletti ; C. Thalmann ; A. M. Lagrange ; M. Janson ; J. C. Augereau ; G. Schneider ; J. Milli ; C. Grady ; J. Debes ; M. Langlois ; D. Mouillet ; T. Henning ; C. Dominik ; A. L. Maire ; J. L. Beuzit ; J. Carson ; K. Dohlen ; N. Engler ; M. Feldt ; T. Fusco ; C. Ginski ; J. H. Girard ; D. Hines ; M. Kasper ; D. Mawet ; F. Menard ; M. R. Meyer ; C. Moutou ; J. Olofsson ; T. Rodigas ; J. F. Sauvage ; J. Schlieder ; H. M. Schmid ; M. Turatto ; S. Udry ; F. Vakili ; A. Vigan ; Z. Wahhaj ; J. Wisniewski
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-10-10Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsPublished by: -
2Latest Papers from Table of Contents or Articles in PressRenner, T. M., Belanger, K., Lam, C., Gerpe, M. C. R., McBane, J. E., Langlois, M.-A.
The American Society for Microbiology (ASM)
Published 2018Staff ViewPublication Date: 2018-02-27Publisher: The American Society for Microbiology (ASM)Print ISSN: 0022-538XElectronic ISSN: 1098-5514Topics: MedicinePublished by: -
3Articles: DFG German National LicensesDIERICK, A.M. ; LANGLOIS, M. ; OOSTVELDT, P. VAN ; ROELS, H.
Oxford, UK : Blackwell Publishing Ltd
Published 1993Staff ViewISSN: 1365-2559Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: The DNA content of the cell nuclei of Ewing's sarcoma was analysed by means of cytophotometry in situ with image analysis in Feulgen-stained sections in 37 patients, and by retrospective flow cytometry according to the method of Hedley in 26 patients. Different histogram patterns were obtained: normal unimodal or bimodal DNA distributions and abnormal DNA distributions with one or two stem lines, or an abnormal DNA distribution with no stem lines. Both methods enabled us to make a distinction between two groups of Ewing's sarcomas with a different prognosis. All patients with aneuploid tumours died within 5 years after the initial diagnosis. Eleven of 19 (58%) patients with a normal DNA distribution in their tumour, as determined by cytophotometry, are still alive and in good health with a mean survival period of 7.5 years, ranging from 2 to 19 years. Of the group of patients in which flow cytometry revealed a normal DNA pattern, eight of 15 (53%) are still alive and in good health, with a mean survival period of 8 years. These results indicate that both techniques are reliable methods for obtaining prognostic information in Ewing's sarcomas. However, cytophotometry in situ yielded a better discrimination for the overall survival (P 〈 0.01) than did flow cytometry (P 〈0.05). In 19% of the cases there was a discrepancy between the DNA histograms obtained with the two techniques. In five of 26 cases the DNA distributions were classified as normal by one method and aneuploid by the other. Tumour cell representation or selective loss of cells during enzymatic treatment may be responsible for this discrepancy.Type of Medium: Electronic ResourceURL: -
4Articles: DFG German National LicensesStaff View
ISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0040-4020Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
9Articles: DFG German National LicensesLanglois, M. ; Soulier, J.L. ; Bremont, B. ; Shen, S. ; Rampillon, V. ; Giudice, A.
Amsterdam : ElsevierStaff ViewISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
10Articles: DFG German National LicensesN-chloromethyl quinuclidinium derivatives: A new class of irreversible ligands for 5-HT"3 receptors.Langlois, M. ; Soulier, J.L. ; Mathe-Allainmat, M. ; Gallais, C. ; Bremont, B. ; Shen, S.
Amsterdam : ElsevierStaff ViewISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0960-894XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
12Articles: DFG German National LicensesLanglois, M. ; Soulier, J. ; Rampillon, V. ; Gallais, C. ; Bremont, B. ; Shen, S. ; Yang, D. ; Giudice, A. ; Sureau, F.
Amsterdam : ElsevierStaff ViewISSN: 0223-5234Keywords: 5-HT"3 receptor antagonist ; fluorescence ; modelling ; naphthalimide ; serotoninSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 0223-5234Keywords: HIV-1 ; aspartyl protease ; peptidic synthesisSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyMedicineType of Medium: Electronic ResourceURL: -
14Articles: DFG German National LicensesStaff View
ISSN: 1572-8838Source: Springer Online Journal Archives 1860-2000Topics: Chemistry and PharmacologyElectrical Engineering, Measurement and Control TechnologyNotes: Abstract Electrolysis of nitration waste sulphuric acid, from the manufacture of trinitrotoluene, results in the formation of a dark solution in which the concentration of aromatics is reduced to much lower levels. The resulting acid can be decolourized by oxidation with H2O2 or by anodic oxidation in the cell. The H2O2-treated electrolysed acid has a nitroaromatic content of 107 p.p.m. and a total carbon content of 278 p.p.m., corresponding to a reduction of 98.7% and 90.3%, respectively. The dark intermediate product appears to result from the anodic oxidation of amines which are initially produced at the cathode, and is destroyed by further anodic oxidation on prolonged electrolysis.Type of Medium: Electronic ResourceURL: -
15Articles: DFG German National LicensesStaff View
ISSN: 1572-9478Source: Springer Online Journal Archives 1860-2000Topics: PhysicsDescription / Table of Contents: Abstract In this article we first of all study the reduction of the equations of movement of the planar three body problem through the introduction of the group of similitude in Poincare's 1-form. This brings out the case of trajectories with zero angular momentum and zero energy. We then consider the reduction of the problem in space by establishing a remarkable link with the planar problem.Notes: Résumé Dans cet article nous étudions, dans un premier temps, la réduction des équations du mouvement du problème plan des 3 corps en introduisant le groupe des similitudes planes dans la 1-forme de Poincaré. Ceci permet de dégager le cas des trajectoires de moment cinétique nul et d'énergie nulle. Nous envisageons ensuite la réduction du problème dans l'espace en établissant un lien remarquable avec le problème plan.Type of Medium: Electronic ResourceURL: -
16Articles: DFG German National LicensesStaff View
ISSN: 1572-9478Source: Springer Online Journal Archives 1860-2000Topics: PhysicsDescription / Table of Contents: Abstract This paper is composed of two parts, the first one established by M. Langlois, the other one by L. Losco. First a study of Poincaré's equations is made, which are Lagrangian equations where use is made of some quasi-coordinates. One application of these equations is very interesting when some coordinates are ignorable in the Lagrangian. A theorem of reduction is obtained with invariant relations. KS is of this kind. Then matrices are constructed which generalize KS. There are matrices of coordinates and quasi-coordinates, which allow application of the theorem of reduction previously obtained. The general motion, helicoidal motion, of a rigid body inR n-space allows to obtain such matrices, just as KS corresponds to a rotation inR 4. Some results have been briefly published in two notes mentioned at the end.Notes: Résumé Cet arricle est composé de deux parties, l'une établie par M. Langlois, l'autre par Mme Losco. La première partie est consacrée à l'étude des équations de Poincaré qui sont les équations de Lagrange du mouvement lorsqu'on introduit des pseudo-paramètres. Une application de ces équations est intéressante à envisager lorsque l'on mélange coordonnées et pseudo-paramètres et que les coordonnées sont ignorables dans le lagrangien. On établit alors un théorème de réduction des équations du mouvement par des relations invariantes. La transformation KS entre dans ce cadre. La seconde partie concerne la construction de matrices généralisant KS. Ce sont des matrices dont les premières lignes définissent des variablesQ α, les dernières lignes des pseudo-paramètres ωλ et pour lesquelles on peut appliquer le théoreme de réduction établi précédemment. Le mouvement général du corps solide dansR n permet une construction de telles matrices, de même que KS est associée à une rotation deR n.Type of Medium: Electronic ResourceURL: -
17Articles: DFG German National LicensesStaff View
ISSN: 1572-9478Source: Springer Online Journal Archives 1860-2000Topics: PhysicsDescription / Table of Contents: Abstract In this paper, we study the geometrical properties of the Euler Poisson's equations of the motion of a heavy rigid body about a fixed point. Two cases are studied. In the first on the rigid body has a gyrostatic moment, constant with respect to itself. It is shown, from the reduction of Euler Poisson's equations, we that we have a presymplectic structure for the initial Euler's equations, and this fact being due to the existence of an invariant volume. Other geometrical consequences are obtained. Secondly the rigid body is considered without its gyrostatic moment. We have here a new property which is the existence of an infinitesimal transformation, due to the homogeneity of the equations. Here the reduction of the equation can be made by an infinity of ways, when it was unique precedently. This study is illustrated by the integrable case of the symetrical top.Notes: Introduction et résumé Le problème de la réduction à l'ordre deux des équations d'Euler-Poisson par les 3 intégrales premières classiques a été étudié par Leimanis en 1971. Dans cet article on se propose de reprendre ce problème d'un point de vue géométrique. On étudie systématiquement les propriétés géométriques des équations d'Euler-Poisson du mouvement du corps solide pesant à point fixe dans deux cas. Dans le premier cas, le corps solide est muni d'un moment gyrostatique constant par rapport à lui-même. On montre ici que la réduction des équations d'Euler-Poisson nous ramène aux trois équations d'Euler initiales avec une structure présymplectique, ceci grâce à la présence d'une forme invariante de volume. D'autres conséquences géométriques sont signalées. Dans le deuxième cas, on supprime le moment gyrostatique. On remarque alors une propriété supplémentaire par rapport au cas précédent: la présence d'une transformation infinitésimale dûe à l'homogénéité des équations. La réduction des équations peut s'effectuer d'une infinité de manières alors qu'elle était unique dans le premier cas. Ceci est illustré par le cas intégrable de la toupie symétrique où l'on met en évidence, de façon originale, les deux quadratures nécessaires.Type of Medium: Electronic ResourceURL: -
18Articles: DFG German National LicensesStaff View
ISSN: 0168-9002Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
19Articles: DFG German National LicensesLanglois, M.-C. ; Vanacker, J.-M. ; Holland, N. D. ; Escriva, H. ; Queva, C. ; Laudet, V. ; Holland, L. Z.
Springer
Published 2000Staff ViewISSN: 1432-041XKeywords: Key words Amphioxus ; Cephalochordate ; Nuclear hormone receptors ; COUP-TF ; Transcription factorsSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract In vertebrates, the orphan nuclear receptors of the COUP-TF group function as negative transcriptional regulators that inhibit the hormonal induction of target genes mediated by classical members of the nuclear hormone superfamily, such as the retinoic acid receptors (RARs) or the thyroid hormone receptors (TRs). To investigate the evolutionary conservation of the roles of COUP-TF receptors as negative regulators in the retinoid and thyroid hormone pathways, we have characterized AmphiCOUP-TF, the homologue of COUP-TFI and COUP-TFII, in the chordate amphioxus (Branchiostoma floridae), the closest living invertebrate relative of the vertebrates. Electrophoretic mobility shift assays (EMSA) showed that AmphiCOUP-TF binds to a wide variety of response elements, as do its vertebrate homologues. Furthermore, AmphiCOUP-TF is a transcriptional repressor that strongly inhibits retinoic acid-mediated transactivation. In situ hybridizations revealed expression of AmphiCOUP-TF in the nerve cord of late larvae, in a region corresponding to hindbrain and probably anterior spinal cord. Although the amphioxus nerve cord appears unsegmented at the gross anatomical level, this pattern reflects segmentation at the cellular level with stripes of expressing cells occurring adjacent to the ends and the centers of each myotomal segment, which may include visceral motor neurons and somatic motor neurons respectively, among other cells. A comparison of the expression pattern of AmphiCOUP-TF with those of its vertebrate homologues, suggests that the roles of COUP-TF in patterning of the nerve cord evolved prior to the split between the amphioxus and vertebrate lineages. Furthermore, in vitro data also suggest that Amphi-COUP-TF acts as a negative regulator of signalling by other nuclear receptors such as RAR, TR or ER.Type of Medium: Electronic ResourceURL: -
20Articles: DFG German National LicensesStaff View
ISSN: 0075-4617Keywords: Chemistry ; Organic ChemistrySource: Wiley InterScience Backfile Collection 1832-2000Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: