Search Results - (Author, Cooperation:M. Laine)
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1F Cosco, M Borrelli, E-M Laine, S Pascazio, A Scardicchio and S Maniscalco
Institute of Physics (IOP)
Published 2018Staff ViewPublication Date: 2018-07-21Publisher: Institute of Physics (IOP)Electronic ISSN: 1367-2630Topics: PhysicsPublished by: -
2Staff View
Publication Date: 2018-11-30Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Superfluidity and superconductivityPublished by: -
3Staff View
Publication Date: 2018-10-17Publisher: American Physical Society (APS)Print ISSN: 1098-0121Electronic ISSN: 1095-3795Topics: PhysicsKeywords: Superfluidity and superconductivityPublished by: -
4L. Backman ; L. Nyberg ; A. Soveri ; J. Johansson ; M. Andersson ; E. Dahlin ; A. S. Neely ; J. Virta ; M. Laine ; J. O. Rinne
American Association for the Advancement of Science (AAAS)
Published 2011Staff ViewPublication Date: 2011-08-06Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Corpus Striatum/*metabolism/radionuclide imaging ; Dopamine/*metabolism ; Humans ; *Learning ; Male ; *Memory, Short-Term ; Positron-Emission Tomography ; Raclopride/metabolism ; Receptors, Dopamine D2/*metabolism ; Young AdultPublished by: -
5HYYPIÄ, T. ; ESKOLA, J. ; LAINE, M. ; SALMI, A. ; MEURMAN, O.
Oxford, UK : Blackwell Publishing Ltd
Published 1985Staff ViewISSN: 1365-3083Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Intensive spontaneous production of IgG by peripheral blood lymphocytes in vitro is detected at the onset of rash in patients with rubella virus infection. The IgG synthesized consists not only of antibodies against rvihella virus specific antigens bul also of antibodies to unrelated viruses.Type of Medium: Electronic ResourceURL: -
6Kemppainen, N. ; Laine, M. ; Laakso, M. P. ; Kaasinen, V. ; Någren, K. ; Vahlberg, T. ; Kurki, T. ; Rinne, J. O.
Oxford, UK : Blackwell Science, Ltd
Published 2003Staff ViewISSN: 1460-9568Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Post mortem studies have revealed a loss of dopamine D2 receptors in the temporal lobes in Alzheimer's disease (AD). Moreover, the role of hippocampal D2 receptors on memory performance has been suggested in experimental studies. However, there are no previous in vivo studies on extrastriatal D2 receptors in AD. Our aim was to examine in vivo whether hippocampal or temporal cortical dopamine D2 receptors are affected in AD and whether D2 receptor availability is associated with the memory dysfunction seen in AD. Fourteen patients with probable AD and 11 age- and sex-matched controls were studied with positron emission tomography using a dopamine D2/D3 receptor antagonist [11C]FLB 457. The D2 receptor binding potentials (BPs) were measured in extrastriatal brain regions and a neuropsychological investigation was performed on the patients with AD. In AD, the D2 receptor availability was reduced in the hippocampus: by 34% (P = 0.03) in the right hippocampus and by 14% (P = 0.78) in the left hippocampus as compared with controls. Multiple linear regression analysis showed that the BP in the right hippocampus had a significant positive association with verbal memory performance (Wechsler Memory Scale – Revised) (P = 0.001) and picture naming (the Boston Naming Test) (P = 0.002). Our findings suggest a role for temporal lobe D2 receptors in the memory and naming performance in AD, and suggest that studies to evaluate the efficiency of dopaminergic medication on patients with early AD might be warranted.Type of Medium: Electronic ResourceURL: -
7Laine, M. L. ; Appelmelk, B. J. ; Winkelhoff, A. J.
Oxford, UK : Blackwell Publishing Ltd
Published 1996Staff ViewISSN: 1600-0765Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Recently van Winkelhoff et al. (1) described 3 novel serotypes in virulent Porphyromomas gingivalis strains, which were based on different polysaccharide antigens. These antigens probably represent capsular structures and have been designated K1, K2 and K3. In the present study we report on 3 novel capsular serotypes, which are represented by P. gingivalis strains ATCC 49417, HG 1690 and HG 1691. The strains, isolated from patients with periodontitis, showed obvious encapsulation in wet India ink preparations. Thermostable antigens could be detected in the supernatant fractions of autoclaved cells. These antigens appeared to be negatively charged, sensitive to periodate degradation, and resistant to proteinase K treatment. On the basis of these characteristics we conclude that the antigens are probably extra-cellular polysaccharides representing a bacterial capsular structure. These K-antigens did not cross-react with K1, K2 or K3 immunesera of P. gingivalis, with the exception of the K2 antiserum, which partially recognized K5- and K6-antigens. In contrast, K5 and K6 antisera did not react with the K2-antigen. After absorbtion of the K2 antiserum with cells of strains HG 1690 (K5) and HG 1691 (K6) cross-reactivity was no longer present. We propose these novel serotypes to be designated: K4 (ATCC 49417), K5 (HG 1960) and K6 (HG 1691).Type of Medium: Electronic ResourceURL: -
8Staff View
ISSN: 0093-934XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Linguistics and Literary StudiesMedicinePsychologyType of Medium: Electronic ResourceURL: -
9Lombardo, A. ; Laine, M. ; Defaye, G. ; Monnier, N. ; Guidicelli, C. ; Chambaz, E.M.
Amsterdam : ElsevierStaff ViewISSN: 0005-2736Keywords: Cytochrome P-450"1"1"β ; Membrane topography ; Steroid hydroxylation ; Trypsin treatmentSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
10Staff View
ISSN: 0005-2728Keywords: Dicarboxylate transport ; MitoplastSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyMedicinePhysicsType of Medium: Electronic ResourceURL: -
11Staff View
ISSN: 0093-934XSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Linguistics and Literary StudiesMedicinePsychologyType of Medium: Electronic ResourceURL: -
12Staff View
ISSN: 0911-6044Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Linguistics and Literary StudiesBiologyMedicineType of Medium: Electronic ResourceURL: -
13Staff View
ISSN: 0014-4827Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyMedicineType of Medium: Electronic ResourceURL: -
14Staff View
ISSN: 0022-4731Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
15Staff View
ISSN: 0022-4731Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Staff View
ISSN: 0022-4731Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
17Van Winkelhoff, A. J. ; Laine, M. L. ; Timmerman, M. F. ; Van der Weijden, G. A. ; Abbas, F. ; Winkel, E. G. ; Arief, E. M. ; Van der Velden, U.
Munksgaard : Munksgaard International Publishers
Published 1999Staff ViewISSN: 1600-051XSource: Blackwell Publishing Journal Backfiles 1879-2005Topics: MedicineNotes: Abstract. In this study, the prevalence and serotype distribution of Porphyromonas gingivalis in an Indonesian population (n=158) is described. The relationship between subgingival P. gingivalis and periodontal attachment loss was investigated. The serotype distribution and periodontal parameters were studied. Serotyping was also used to study person-to-person transmission between siblings and between spouses. Approximately 50% of the subjects had periodontal attachment loss ≥3 mm at 1 or more recorded sites. The population was divided into 2 subgroups based on the presence or absence of P. gingivalis. No differences in plaque index, pocket depth, clinical attachment loss, bleeding upon probing, % of sites with ≥3 mm clinical attachment loss and % of sites with probing pocket depth 〉5 mm, were observed between both sub-populations. All known 6 capsular serotypes were found in the study population, with the exception of the K1 type. Detection of 1 of the known P. gingivalis serotypes was not related with the amount of clinical attachment loss. In 3 out of 29 sibships with more than one member positive for P. gingivalis, an identical P. gingivalis serotype was found. None of the 15 couples in the study shared an identical P. gingivalis serotype, indicating that transmission is probably not a common phenomenon in this population.Type of Medium: Electronic ResourceURL: -
18Berger, F. ; Laine, M. ; Amalfitano, G. ; Brunet, J.F. ; Verna, J.M. ; Nissou, M.F. ; Benabid, A.L.
Amsterdam : ElsevierStaff ViewISSN: 0014-5793Keywords: Cystic fluid ; EGF-R ; Gliomas ; Inhibitory effect ; Proto-oncogene ; Tyrosine kinaseSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
19Staff View
ISSN: 0960-0760Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: -
20Staff View
ISSN: 0960-0760Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyType of Medium: Electronic ResourceURL: