Search Results - (Author, Cooperation:M. L. Matthews)

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  1. 1
    Staff View
    Publication Date:
    2013-07-23
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Biocatalysis ; Halogenation ; Hydroxylation ; Iron/*chemistry ; Oxidoreductases/*chemistry/metabolism ; Pseudomonas syringae/enzymology
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    MATTHEWS, M. L.

    [s.l.] : Nature Publishing Group
    Published 1968
    Staff View
    ISSN:
    1476-4687
    Source:
    Nature Archives 1869 - 2009
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Notes:
    [Auszug] At a neurophysiological level, Ratliff and Hartline3 have shown that the changes in sensitivity occurring adjacent to a border or gradient of illumination can be attributed to the action of lateral inhibition in the case of Limulus. Baumgartner4 has shown similar action in the cat retina using a ...
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses
  3. 3
    Staff View
    ISSN:
    1432-1912
    Keywords:
    ß-Adrenoceptors ; Clenbuterol ; Growth ; Skeletal muscle ; Heart
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Notes:
    Summary The aim of the present study was to determine whether the anabolic effects of clenbuterol in rat skeletal muscle are mediated by ß2-adrenoceptor stimulation. Female rats were treated with clenbuterol, alone or in combination with either the nonselective ß1/ß2-adrenoceptor antagonist sotalol, or the ß2-adrenoceptor-selective antagonist ICI118551. Clenbuterol caused an increase in muscle growth, accompanied by a reduction in ß2-adrenoceptor density in the rat hind-limb. Both actions were attenuated by sotalol. However, at the dose tested ICI118551 was the more effective antagonist of the muscle growth response, and when given alone, ICI118551 caused significant muscle atrophy. An increase in the weight of the heart was also observed in clenbuterol-treated rats, and again while this effect was attenuated by sotalol, it was reversed by ICI118551. It is concluded that ß2-adrenoceptors mediate the anabolic effects of clenbuterol in cardiac and skeletal muscle, and that they play an important physiological role in the growth and maintenance of muscle mass in the rat hind-limb.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses