Search Results - (Author, Cooperation:M. Keil)
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1D. P. Hibar ; J. L. Stein ; M. E. Renteria ; A. Arias-Vasquez ; S. Desrivieres ; N. Jahanshad ; R. Toro ; K. Wittfeld ; L. Abramovic ; M. Andersson ; B. S. Aribisala ; N. J. Armstrong ; M. Bernard ; M. M. Bohlken ; M. P. Boks ; J. Bralten ; A. A. Brown ; M. M. Chakravarty ; Q. Chen ; C. R. Ching ; G. Cuellar-Partida ; A. den Braber ; S. Giddaluru ; A. L. Goldman ; O. Grimm ; T. Guadalupe ; J. Hass ; G. Woldehawariat ; A. J. Holmes ; M. Hoogman ; D. Janowitz ; T. Jia ; S. Kim ; M. Klein ; B. Kraemer ; P. H. Lee ; L. M. Olde Loohuis ; M. Luciano ; C. Macare ; K. A. Mather ; M. Mattheisen ; Y. Milaneschi ; K. Nho ; M. Papmeyer ; A. Ramasamy ; S. L. Risacher ; R. Roiz-Santianez ; E. J. Rose ; A. Salami ; P. G. Samann ; L. Schmaal ; A. J. Schork ; J. Shin ; L. T. Strike ; A. Teumer ; M. M. van Donkelaar ; K. R. van Eijk ; R. K. Walters ; L. T. Westlye ; C. D. Whelan ; A. M. Winkler ; M. P. Zwiers ; S. Alhusaini ; L. Athanasiu ; S. Ehrlich ; M. M. Hakobjan ; C. B. Hartberg ; U. K. Haukvik ; A. J. Heister ; D. Hoehn ; D. Kasperaviciute ; D. C. Liewald ; L. M. Lopez ; R. R. Makkinje ; M. Matarin ; M. A. Naber ; D. R. McKay ; M. Needham ; A. C. Nugent ; B. Putz ; N. A. Royle ; L. Shen ; E. Sprooten ; D. Trabzuni ; S. S. van der Marel ; K. J. van Hulzen ; E. Walton ; C. Wolf ; L. Almasy ; D. Ames ; S. Arepalli ; A. A. Assareh ; M. E. Bastin ; H. Brodaty ; K. B. Bulayeva ; M. A. Carless ; S. Cichon ; A. Corvin ; J. E. Curran ; M. Czisch ; G. I. de Zubicaray ; A. Dillman ; R. Duggirala ; T. D. Dyer ; S. Erk ; I. O. Fedko ; L. Ferrucci ; T. M. Foroud ; P. T. Fox ; M. Fukunaga ; J. R. Gibbs ; H. H. Goring ; R. C. Green ; S. Guelfi ; N. K. Hansell ; C. A. Hartman ; K. Hegenscheid ; A. Heinz ; D. G. Hernandez ; D. J. Heslenfeld ; P. J. Hoekstra ; F. Holsboer ; G. Homuth ; J. J. Hottenga ; M. Ikeda ; C. R. Jack, Jr. ; M. Jenkinson ; R. Johnson ; R. Kanai ; M. Keil ; J. W. Kent, Jr. ; P. Kochunov ; J. B. Kwok ; S. M. Lawrie ; X. Liu ; D. L. Longo ; K. L. McMahon ; E. Meisenzahl ; I. Melle ; S. Mohnke ; G. W. Montgomery ; J. C. Mostert ; T. W. Muhleisen ; M. A. Nalls ; T. E. Nichols ; L. G. Nilsson ; M. M. Nothen ; K. Ohi ; R. L. Olvera ; R. Perez-Iglesias ; G. B. Pike ; S. G. Potkin ; I. Reinvang ; S. Reppermund ; M. Rietschel ; N. Romanczuk-Seiferth ; G. D. Rosen ; D. Rujescu ; K. Schnell ; P. R. Schofield ; C. Smith ; V. M. Steen ; J. E. Sussmann ; A. Thalamuthu ; A. W. Toga ; B. J. Traynor ; J. Troncoso ; J. A. Turner ; M. C. Valdes Hernandez ; D. van 't Ent ; M. van der Brug ; N. J. van der Wee ; M. J. van Tol ; D. J. Veltman ; T. H. Wassink ; E. Westman ; R. H. Zielke ; A. B. Zonderman ; D. G. Ashbrook ; R. Hager ; L. Lu ; F. J. McMahon ; D. W. Morris ; R. W. Williams ; H. G. Brunner ; R. L. Buckner ; J. K. Buitelaar ; W. Cahn ; V. D. Calhoun ; G. L. Cavalleri ; B. Crespo-Facorro ; A. M. Dale ; G. E. Davies ; N. Delanty ; C. Depondt ; S. Djurovic ; W. C. Drevets ; T. Espeseth ; R. L. Gollub ; B. C. Ho ; W. Hoffmann ; N. Hosten ; R. S. Kahn ; S. Le Hellard ; A. Meyer-Lindenberg ; B. Muller-Myhsok ; M. Nauck ; L. Nyberg ; M. Pandolfo ; B. W. Penninx ; J. L. Roffman ; S. M. Sisodiya ; J. W. Smoller ; H. van Bokhoven ; N. E. van Haren ; H. Volzke ; H. Walter ; M. W. Weiner ; W. Wen ; T. White ; I. Agartz ; O. A. Andreassen ; J. Blangero ; D. I. Boomsma ; R. M. Brouwer ; D. M. Cannon ; M. R. Cookson ; E. J. de Geus ; I. J. Deary ; G. Donohoe ; G. Fernandez ; S. E. Fisher ; C. Francks ; D. C. Glahn ; H. J. Grabe ; O. Gruber ; J. Hardy ; R. Hashimoto ; H. E. Hulshoff Pol ; E. G. Jonsson ; I. Kloszewska ; S. Lovestone ; V. S. Mattay ; P. Mecocci ; C. McDonald ; A. M. McIntosh ; R. A. Ophoff ; T. Paus ; Z. Pausova ; M. Ryten ; P. S. Sachdev ; A. J. Saykin ; A. Simmons ; A. Singleton ; H. Soininen ; J. M. Wardlaw ; M. E. Weale ; D. R. Weinberger ; H. H. Adams ; L. J. Launer ; S. Seiler ; R. Schmidt ; G. Chauhan ; C. L. Satizabal ; J. T. Becker ; L. Yanek ; S. J. van der Lee ; M. Ebling ; B. Fischl ; W. T. Longstreth, Jr. ; D. Greve ; H. Schmidt ; P. Nyquist ; L. N. Vinke ; C. M. van Duijn ; L. Xue ; B. Mazoyer ; J. C. Bis ; V. Gudnason ; S. Seshadri ; M. A. Ikram ; N. G. Martin ; M. J. Wright ; G. Schumann ; B. Franke ; P. M. Thompson ; S. E. Medland
Nature Publishing Group (NPG)
Published 2015Staff ViewPublication Date: 2015-01-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aging/genetics ; Apoptosis/genetics ; Brain/*anatomy & histology ; Caudate Nucleus/anatomy & histology ; Child ; Female ; Gene Expression Regulation, Developmental/genetics ; Genetic Loci/genetics ; Genetic Variation/*genetics ; *Genome-Wide Association Study ; Hippocampus/anatomy & histology ; Humans ; Magnetic Resonance Imaging ; Male ; Membrane Proteins/genetics ; Middle Aged ; Organ Size/genetics ; Putamen/anatomy & histology ; Sex Characteristics ; Skull/anatomy & histology ; Young AdultPublished by: -
2T. Schumacher ; L. Bunse ; S. Pusch ; F. Sahm ; B. Wiestler ; J. Quandt ; O. Menn ; M. Osswald ; I. Oezen ; M. Ott ; M. Keil ; J. Balss ; K. Rauschenbach ; A. K. Grabowska ; I. Vogler ; J. Diekmann ; N. Trautwein ; S. B. Eichmuller ; J. Okun ; S. Stevanovic ; A. B. Riemer ; U. Sahin ; M. A. Friese ; P. Beckhove ; A. von Deimling ; W. Wick ; M. Platten
Nature Publishing Group (NPG)
Published 2014Staff ViewPublication Date: 2014-07-22Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Animals ; Antibody Specificity ; Antigens, Neoplasm/genetics/immunology ; Cancer Vaccines/*immunology/*therapeutic use ; Female ; Glioma/enzymology/genetics/*immunology/*therapy ; Histocompatibility Antigens Class II/immunology ; Humans ; Immunity, Humoral ; Immunotherapy/methods ; Isocitrate Dehydrogenase/*genetics/*immunology ; Male ; Mice ; Mutant Proteins/genetics/*immunology ; Mutation ; T-Lymphocytes, Helper-Inducer/immunology ; Xenograft Model Antitumor AssaysPublished by: -
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Type of Medium: articlePublication Date: 1991Keywords: Schuljahr 01 ; Schuljahr 02 ; Schuljahr 03 ; Schuljahr 04 ; Schuljahr 05 ; Schuljahr 06 ; Schuljahr 07 ; Schuljahr 08 ; Schuljahr 09 ; Schuljahr 10 ; Schuljahr 11 ; Schuljahr 12 ; Schuljahr 13 ; Sekundarstufe I ; Sekundarstufe II ; Sekundarbereich ; Curriculum ; Lehrplan ; Lehrplangestaltung ; Unterrichtsmaterial ; Biologie ; Sachunterricht ; EmpfehlungIn: Der mathematische und naturwissenschaftliche Unterricht, Bd. 44 (1991) H. 6, S. I-IV, 0025-5866Language: GermanNote: Literaturangaben -
4Keil, M. ; Krämer, H.-G. ; Kudell, A. ; Baig, M.A. ; Zhu, J. ; Demtröder, W.
College Park, Md. : American Institute of Physics (AIP)
Published 2000Staff ViewISSN: 1089-7690Source: AIP Digital ArchiveTopics: PhysicsChemistry and PharmacologyNotes: Based on resonant two-photon ionization of 21Li3 with cw lasers and mass-selective detection of 21Li3+ ions by a quadrupole mass spectrometer, isotope-selective rotationally resolved spectra of vibronic bands in the electronic A 2E″←X 2E′ system have been recorded. The complex but completely resolved spectra could be analyzed using optical–optical double resonance techniques in combination with accurate ab initio calculations which provide potential energy surfaces and rovibronic term values for both electronic states. A detailed comparison between experimental and theoretical results for the (vs′=0, vb′=0, va′=0)←(vs″=0, vb″=0, va″=0) band demonstrates excellent agreement. The coupling between pseudorotation and rotational motion is shown to produce complex level patterns which, however, can be accurately represented by an effective pseudo/rotation Hamiltonian in terms of rotational and coupling constants that directly provide structural information. For both electronic states the nuclear dynamics is adequately described as a motion on a single adiabatic potential surface with a geometric phase π for closed loops around the conical intersection at D3h geometries. © 2000 American Institute of Physics.Type of Medium: Electronic ResourceURL: -
5Kloc, C. ; Lux-Steiner, M.C. ; Keil, M. ; Baumann, J.R. ; Doll, G. ; Bucher, E.
Amsterdam : ElsevierStaff ViewISSN: 0022-0248Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyGeosciencesPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0038-1098Keywords: A. fullerenes ; D. electron-phonon interaction ; E. electron paramagnetic resonance ; organic crystalsSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: PhysicsType of Medium: Electronic ResourceURL: -
7Prat, S. ; Frommer, W.B. ; Hofgen, R. ; Keil, M. ; Koszmann, J. ; Koster-Topfer, M. ; Liu, X.-J. ; Muller, B. ; Pena-Cortes, H. ; Sanchez-Serrano, J.J. ; Willmitzer, L. ; Rocha-Sosa, M. ; Sonnewald, U.
Amsterdam : ElsevierStaff ViewISSN: 0014-5793Keywords: Patatin ; Proteinase inhibitor II ; Starch metabolism ; TuberizationSource: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: BiologyChemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
10Werner, H. ; Herein, D. ; Blocker, J. ; Henschke, B. ; Tegtmeyer, U. ; Schedel-Niedrig, T. ; Keil, M. ; Bradshaw, A.M. ; Schlogl, R.
Amsterdam : ElsevierStaff ViewISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 0009-2614Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyPhysicsType of Medium: Electronic ResourceURL: -
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ISSN: 1420-9071Source: Springer Online Journal Archives 1860-2000Topics: BiologyMedicineNotes: Zusammenfassung Die bisherigen Untersuchungen über Wachstum der Moose in Dunkelkulturen ergaben, daß die Moose ohne Lichtzutritt nur Protonema zu bilden fähig sind. Neue Versuche, über die berichtet wird, mit der Kultur der Moose,Splachnum sphaericum L. fil.,Splachnum ampullaceum L. undTrematodon ambiguus Hornsch, hatten ein entgegengesetztes Resultat. Die genannten Moose bildeten in Dunkelkulturen auf festem Agarnährboden wie auch in flüssigem Medium mit Saccharosezusatz Gametophyten. Die unter diesen Bedingungen gebildeten Gametophyten waren chlorophyllfrei und die Phylloide waren schuppenförmig. Aus diesen und anderen jetzt durchgeführten Versuchen ist zu schliessen, daß nicht das Licht, sondern die Nährstoffart und der Nährstoffvorrat für die Gametophytenentstehung bestimmend ist.Type of Medium: Electronic ResourceURL: -
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ISSN: 0040-4039Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002Topics: Chemistry and PharmacologyType of Medium: Electronic ResourceURL: -
16Dreher, J.-C. ; Trapp, W. ; Banquet, J.-P. ; Keil, M. ; Günther, W. ; Burnod, Y.
Springer
Published 1999Staff ViewISSN: 1432-1106Keywords: Key words Electrophysiology ; Schizophrenia ; Readiness potential ; Motor planning ; Frontal CortexSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract To test the hypothesis of a planning dysfunction in schizophrenia using a precise temporal definition, the readiness potential (RP), a negative cortical wave preceding self-initiated movements and reflecting motor preparation processes, was studied in patients under stable medication and in controls. The supplementary motor area (SMA), known to be involved in the generation of the RP, has also been implicated in movement selection (fixed versus free) and complexity (single versus sequence). This is the first study using RP for the assessment of the influence of these factors on motor preparation in schizophrenics. Our results show that schizophrenics’ RP amplitude is significantly lower than in controls at central and contralateral electrodes. However, RP amplitude increases with task difficulty in both groups, offering important new insight into classical SMA hypoactivation in schizophrenics performing motor tasks. Topographic analysis shows that RP amplitude is, for both groups, significantly higher in sequence than in single movements at fronto-central sites and higher for free than for fixed movements at centro-parietal sites. Finally, RP onset occurs significantly later in schizophrenics than in controls. These results support the view of a motor-preparation and decision-making dysfunction in schizophrenia. They are interpreted within the framework of a fronto-striatal disorder in this disease.Type of Medium: Electronic ResourceURL: -
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ISSN: 1432-2242Keywords: Eucalyptus ; RAPD markers DNA fingerprinting ; Genotype mis-identifications BreedingSource: Springer Online Journal Archives 1860-2000Topics: BiologyNotes: Abstract We carried out four separate studies using random amplified polymorphic DNA (RAPD) markers to analyse samples of Eucalyptus supplied by several different organisations. The objective was to examine the reproducibility of the RAPD technique and its ability to discriminate between individual genotypes for verification of clonal identities. We found that RAPD profiles that are unique to a genotype can be generated reliably and simply and that even closely related genotypes can be distinguished. In addition, in each of the four studies, we detected cases where the plant material studied had been mis-sampled or mis-labelled (i.e. the RAPD profiles were not consistent with the identification numbers): (1) ramets of a Eucalyptus grandis clone were found to be derived from 2 different clones; (2) ramets labelled as 2 different Eucalyptus hybrid clones were found to be the same clone, owing to a mis-planted clonal hedge; (3) samples supplied as a single progeny of a controlled E. nitens cross were derived from two crosses involving different pairs of parents; (4) mis-labelling was detected for ramets of 4 of a set of 10 clones of E. grandis and E. camaldulensis. For three of the four studies, the detection of genotype mis-identifications was unexpected, suggesting that labelling or sampling errors during the handling of plant material are a frequent occurrence, with potentially serious economic consequences.Type of Medium: Electronic ResourceURL: -
18Martorana, P.A. ; Ruetten, H. ; Goebel, B. ; Koehl, D. ; Roegner, B. ; Schoelkens, B.A. ; Keil, M.
Springer
Published 1999Staff ViewISSN: 1435-1803Keywords: Key words Angiotensin converting enzyme inhibition – ischemia and reperfusion – endothelial dysfunction – dogSource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract We investigated the effect of an infusion of ramiprilat on the development of coronary endothelial dysfunction. In anesthetized dogs, the endothelium-dependent vasodilators acetylcholine (ACh, 5 and 10 μg · min−1 for 1 min) and serotonin (5-HT, 50 and 100 μg · min−1 for 1 min) and the endothelium-independent vasodilator nitroglycerin (NTG, 50 and 100 μg · min−1 for 1 min) were given intracoronarily (i.c.) both prior to and after 60 min of ischemia (I) and 180 min of reperfusion R of a coronary artery. During I/R the dogs received i.c. either saline (N = 22) or ramiprilat (40 ng/kg · min−1, N = 14). At the end of the experiment, a biopsy of the most distal coronary bed was processed for scanning electron microscopy (SEM). Prior to I/R all vasodilators induced a similar dose-related increase in coronary flow in both groups. Following I/R, in controls the responses to ACh and 5-HT were significantly blunted (ACh: −39 % and −34 %; 5-HT: −48 % and −49 %); those to NTG were unchanged. Ramiprilat significantly prevented the blunting of the responses to ACh (−5 %, and −10 %) and 5-HT (−11 %, and −19 %). SEM of control subepicardial arterioles showed adhesion of leukocytes to the endothelium and crater formation. No craters were seen in the ramiprilat-treated dogs. Thus, an acute infusion of ramiprilat significantly prevents the development of coronary endothelial dysfunction. Additionally, the appearance of crater-like changes on the endothelial surface can be taken as a morphological marker of endothelial dysfunction.Type of Medium: Electronic ResourceURL: -
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ISSN: 1435-1803Keywords: Key words Ischemia-reperfusion – endothelial dysfunction – coronary artery – dog – scanning electron microscopySource: Springer Online Journal Archives 1860-2000Topics: MedicineNotes: Abstract Coronary endothelial dysfunction is characterized by a lower response to endothelium-dependent vasodilators such as acetylcholine (ACh) and serotonin (5-HT), but by an unaltered response to endothelium-independent vasodilators such as nitroglycerin (NTG). In the present study, we investigated the vasoreactivity of the coronary bed in vivo, in a dog model of ischemia and reperfusion (I/R). We also assessed the morphology of the subepicardial arterioles and capillary bed by means of scanning electron microscopy (SEM). Anesthetized, instrumented dogs were divided in two groups. One group (N=27) was submitted to ischemia (60 min) and reperfusion (180 min) of the left circumflex coronary artery, the second group (N=8) was sham-operated. Prior to and following I/R, ACh, 5-HT, and NTG were given intracoronarily. At the end of the experiment a 1 cm3 myocardial biopsy was processed for SEM. The sham-operated dogs showed a reduction of basal coronary flow of 11%, but the vasoreactivity to ACh and 5-HT remained constant. In the I/R group, basal coronary flow was reduced by 35% (p〈0.05), and the vasoreactivity to ACh and 5-HT, but not to NTG, was significantly blunted. At SEM the arterioles of the dogs submitted to I/R showed a marked adhesion of leukocytes associated with holes an the endothelial surface, while the capillary bed was free of changes and patent. Thus, following I/R, coronary endothelial dysfunction could be demonstrated in vivo by the blunting of the vasoreactive responses to two different endothelium-dependent vasodilators. The responses to NTG were not affected, probably because the function of the smooth muscle cell was preserved, and the capillary bed was patent.Type of Medium: Electronic ResourceURL: -
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ISSN: 1573-5060Keywords: Alstroemeria ; genetic fingerprinting ; RAPD ; somaclonal variation ; alstroemeriaSource: Springer Online Journal Archives 1860-2000Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, NutritionNotes: Summary We have used random amplified polymorphic DNA (RAPD) markers to study genetic variation in Alstroemeria. The first objective was to examine the discriminatory power of RAPD markers in different genotypes of Alstroemeria obtained by traditional breeding. All genotypes examined, including commercial Alstroemeria varieties, could be distinguished on the basis of their RAPD profiles. Progeny plants could be distinguished from their parents. A second objective of this study was to investigate whether RAPD markers can be used as a routine tool to detect mutant plants, as an alternative to glasshouse testing. To address this objective, we analysed Alstroemeria plants that carried phenotypically visible mutations that either were induced by irradiation using X-rays or were the result of somaclonal variation. In eight out of a total of 13 mutant Alstroemeria plants obtained after irradiation or tissue culture we detected no polymorphisms when compared to control plants that were considered to be non-mutated. Only in five of the mutant plants analysed we detected one to two polymorphisms. These results suggest that frequent genome rearrangements had not occurred in the mutant plants analysed. These results also demonstrate that the RAPD technique is an inappropriate tool for the rapid screening of Alstroemeria for induced variation. It that the RAPD technique is an inappropriate tool for the rapid screening of Alstroemeria for induced variation. It seems probable that this conclusion would be equally applicable in other plant genera in which induced variation has occurred. However, the RAPD technique is a simple and effective tool for genetic fingerprinting of Alstroemeria varieties, provided their differences are due to sexual propagation.Type of Medium: Electronic ResourceURL: