Search Results - (Author, Cooperation:M. J. Elmore)

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  1. 1
    M. W. Carroll ; D. A. Matthews ; J. A. Hiscox ; M. J. Elmore ; G. Pollakis ; A. Rambaut ; R. Hewson ; I. Garcia-Dorival ; J. A. Bore ; R. Koundouno ; S. Abdellati ; B. Afrough ; J. Aiyepada ; P. Akhilomen ; D. Asogun ; B. Atkinson ; M. Badusche ; A. Bah ; S. Bate ; J. Baumann ; D. Becker ; B. Becker-Ziaja ; A. Bocquin ; B. Borremans ; A. Bosworth ; J. P. Boettcher ; A. Cannas ; F. Carletti ; C. Castilletti ; S. Clark ; F. Colavita ; S. Diederich ; A. Donatus ; S. Duraffour ; D. Ehichioya ; H. Ellerbrok ; M. D. Fernandez-Garcia ; A. Fizet ; E. Fleischmann ; S. Gryseels ; A. Hermelink ; J. Hinzmann ; U. Hopf-Guevara ; Y. Ighodalo ; L. Jameson ; A. Kelterbaum ; Z. Kis ; S. Kloth ; C. Kohl ; M. Korva ; A. Kraus ; E. Kuisma ; A. Kurth ; B. Liedigk ; C. H. Logue ; A. Ludtke ; P. Maes ; J. McCowen ; S. Mely ; M. Mertens ; S. Meschi ; B. Meyer ; J. Michel ; P. Molkenthin ; C. Munoz-Fontela ; D. Muth ; E. N. Newman ; D. Ngabo ; L. Oestereich ; J. Okosun ; T. Olokor ; R. Omiunu ; E. Omomoh ; E. Pallasch ; B. Palyi ; J. Portmann ; T. Pottage ; C. Pratt ; S. Priesnitz ; S. Quartu ; J. Rappe ; J. Repits ; M. Richter ; M. Rudolf ; A. Sachse ; K. M. Schmidt ; G. Schudt ; T. Strecker ; R. Thom ; S. Thomas ; E. Tobin ; H. Tolley ; J. Trautner ; T. Vermoesen ; I. Vitoriano ; M. Wagner ; S. Wolff ; C. Yue ; M. R. Capobianchi ; B. Kretschmer ; Y. Hall ; J. G. Kenny ; N. Y. Rickett ; G. Dudas ; C. E. Coltart ; R. Kerber ; D. Steer ; C. Wright ; F. Senyah ; S. Keita ; P. Drury ; B. Diallo ; H. de Clerck ; M. Van Herp ; A. Sprecher ; A. Traore ; M. Diakite ; M. K. Konde ; L. Koivogui ; N. Magassouba ; T. Avsic-Zupanc ; A. Nitsche ; M. Strasser ; G. Ippolito ; S. Becker ; K. Stoecker ; M. Gabriel ; H. Raoul ; A. Di Caro ; R. Wolfel ; P. Formenty ; S. Gunther
    Nature Publishing Group (NPG)
    Published 2015
    Staff View
    Publication Date:
    2015-06-18
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Elmore, M. J. ; Lamb, A. J. ; Ritchie, G. Y. ; Douglas, R. M. ; Munro, A. ; Gajewska, A. ; Booth, I. R.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1990
    Staff View
    ISSN:
    1365-2958
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Biology
    Medicine
    Notes:
    The mechanism by which N-ethylmaleimide (NEM) elicits potassium efflux from Escherichia coli has been investigated. The critical factor is the formation of specific glutathione metabolites that activate transport systems encoded by the kefB and kefC gene products. Formation of N-ethyl-succinimido-S-glutathione (ESG) leads to the activation of potassium efflux via these transport systems. The addition of dithiothreitol and other reducing agents to cells reverses this process by causing the breakdown of ESG and thus removing the activator of the systems. Chlorodinitrobenzene, p-chloromercuribenzoate and phenylmaleimide provoke similar effects to NEM. Iodoacetate, which leads to the formation of S-carboxymethyl-glutathione, does not activate the systems but does prevent the action of NEM. It is concluded that the KefB and KefC systems are gated by glutathione metabolites and that the degree to which they are activated is dependent upon the nature of the substituent on the sulphydryl group.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2958.1990.tb00607.x

    Articles: DFG German National Licenses