Search Results - (Author, Cooperation:M. I. Kuroda)

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  1. 1
    J. W. Ho ; Y. L. Jung ; T. Liu ; B. H. Alver ; S. Lee ; K. Ikegami ; K. A. Sohn ; A. Minoda ; M. Y. Tolstorukov ; A. Appert ; S. C. Parker ; T. Gu ; A. Kundaje ; N. C. Riddle ; E. Bishop ; T. A. Egelhofer ; S. S. Hu ; A. A. Alekseyenko ; A. Rechtsteiner ; D. Asker ; J. A. Belsky ; S. K. Bowman ; Q. B. Chen ; R. A. Chen ; D. S. Day ; Y. Dong ; A. C. Dose ; X. Duan ; C. B. Epstein ; S. Ercan ; E. A. Feingold ; F. Ferrari ; J. M. Garrigues ; N. Gehlenborg ; P. J. Good ; P. Haseley ; D. He ; M. Herrmann ; M. M. Hoffman ; T. E. Jeffers ; P. V. Kharchenko ; P. Kolasinska-Zwierz ; C. V. Kotwaliwale ; N. Kumar ; S. A. Langley ; E. N. Larschan ; I. Latorre ; M. W. Libbrecht ; X. Lin ; R. Park ; M. J. Pazin ; H. N. Pham ; A. Plachetka ; B. Qin ; Y. B. Schwartz ; N. Shoresh ; P. Stempor ; A. Vielle ; C. Wang ; C. M. Whittle ; H. Xue ; R. E. Kingston ; J. H. Kim ; B. E. Bernstein ; A. F. Dernburg ; V. Pirrotta ; M. I. Kuroda ; W. S. Noble ; T. D. Tullius ; M. Kellis ; D. M. MacAlpine ; S. Strome ; S. C. Elgin ; X. S. Liu ; J. D. Lieb ; J. Ahringer ; G. H. Karpen ; P. J. Park
    Nature Publishing Group (NPG)
    Published 2014
    Staff View
    Publication Date:
    2014-08-29
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Caenorhabditis elegans/*cytology/*genetics ; Cell Line ; Centromere/genetics/metabolism ; Chromatin/chemistry/*genetics/*metabolism ; Chromatin Assembly and Disassembly/genetics ; DNA Replication/genetics ; Drosophila melanogaster/*cytology/*genetics ; Enhancer Elements, Genetic/genetics ; Epigenesis, Genetic ; Heterochromatin/chemistry/genetics/metabolism ; Histones/chemistry/metabolism ; Humans ; Molecular Sequence Annotation ; Nuclear Lamina/metabolism ; Nucleosomes/chemistry/genetics/metabolism ; Promoter Regions, Genetic/genetics ; Species Specificity
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2010-12-24
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; Cell Line ; Chromatin/*genetics/*metabolism ; Chromatin Immunoprecipitation ; Chromosomal Proteins, Non-Histone/analysis/metabolism ; Deoxyribonuclease I/metabolism ; Drosophila Proteins/genetics ; Drosophila melanogaster/embryology/*genetics/growth & development ; Exons/genetics ; Gene Expression Regulation/genetics ; Genes, Insect/genetics ; Genome, Insect/genetics ; Histones/chemistry/metabolism ; Male ; Molecular Sequence Annotation ; Oligonucleotide Array Sequence Analysis ; Polycomb Repressive Complex 1 ; RNA/analysis/genetics ; Sequence Analysis ; Transcription, Genetic/genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  3. 3
    F. Ferrari ; Y. L. Jung ; P. V. Kharchenko ; A. Plachetka ; A. A. Alekseyenko ; M. I. Kuroda ; P. J. Park
    American Association for the Advancement of Science (AAAS)
    Published 2013
    Staff View
    Publication Date:
    2013-04-20
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Animals ; DNA Polymerase II/*metabolism ; *Dosage Compensation, Genetic ; Drosophila/*genetics ; Drosophila Proteins/*metabolism ; Female ; *Genes, X-Linked ; Male ; *Promoter Regions, Genetic ; X Chromosome/*genetics
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  4. 4
    E. Larschan ; E. P. Bishop ; P. V. Kharchenko ; L. J. Core ; J. T. Lis ; P. J. Park ; M. I. Kuroda
    Nature Publishing Group (NPG)
    Published 2011
    Staff View
    Publication Date:
    2011-03-04
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Keywords:
    Acetylation ; Animals ; Cell Line ; Chromosomes, Insect/*genetics/metabolism ; DNA-Binding Proteins/genetics/metabolism ; Dosage Compensation, Genetic/*genetics ; Drosophila Proteins/genetics/metabolism ; Drosophila melanogaster/enzymology/*genetics ; Genes, Insect/genetics ; Genes, X-Linked/genetics ; Histones/chemistry/metabolism ; Male ; Nuclear Proteins/genetics/metabolism ; RNA Polymerase II/metabolism ; Sequence Analysis, DNA ; Transcription Factors/genetics/metabolism ; *Transcription, Genetic/genetics ; X Chromosome/*genetics/metabolism
    Published by:
    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    ISSN:
    1573-6849
    Keywords:
    dosage compensation ; Drosophila ; histone acetylation ; nuclear domains
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Biology
    Notes:
    Abstract In the fruit flyDrosophila, dosage compensation involves several proteins acting in concert to double the transcriptional activity of genes on the single male X chromosome. Three of these proteins, MLE, MSL-1 and histone H4 acetylated at lysine 16 (H4Ac16), have recently been shown to be located almost exclusively on the male X chromosome in interphase (polytene) cells. We show here that in neuroblasts from third instarDrosophila larvae antisera to H4Ac16, MLE and MSL-1 uniquely label the distal, euchromatic region of the male X chromosome through mitosis. The centromere-proximal, heterochromatic region of the male X is not labelled with these antisera, nor are male autosomes or any chromosomes in female cells. That the association of H4Ac16 with the male X chromosome persists, even when the chromosome is maximally compacted and transcriptionally quiescent, argues that this modified histone is an integral component of the dosage compensation pathway. In the nuclei of interphase neuroblasts from male (but never female) larvae, antibodies to H4Ac16 revealed a small, brightly labelled patch against a background of generally weak nuclear staining. In double-labelling experiments, this patch was also labelled, albeit comparatively weakly, with antibodies to MSL-1. These results strongly suggest that the distal, euchromatic region of the X chromosome in male cells occupies a limited and relatively compact nuclear domain.
    Type of Medium:
    Electronic Resource
    URL:
    Articles: DFG German National Licenses