Search Results - (Author, Cooperation:M. Honma)

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  1. 1
    Staff View
    Publication Date:
    2016-02-26
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  2. 2
    Staff View
    Publication Date:
    2012-09-29
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  3. 3
    Staff View
    Publication Date:
    2013-10-11
    Publisher:
    Nature Publishing Group (NPG)
    Print ISSN:
    0028-0836
    Electronic ISSN:
    1476-4687
    Topics:
    Biology
    Chemistry and Pharmacology
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.nature.com/

    Latest Papers from Table of Contents or Articles in Press
  4. 4
    Staff View
    Publication Date:
    2016-01-20
    Publisher:
    American Association for the Advancement of Science (AAAS)
    Print ISSN:
    0036-8075
    Electronic ISSN:
    1095-9203
    Topics:
    Biology
    Chemistry and Pharmacology
    Computer Science
    Medicine
    Natural Sciences in General
    Physics
    Published by:
    http://www.aaas.org/

    Latest Papers from Table of Contents or Articles in Press
  5. 5
    Staff View
    Publication Date:
    2018-07-10
    Publisher:
    American Physical Society (APS)
    Print ISSN:
    0556-2813
    Electronic ISSN:
    1089-490X
    Topics:
    Physics
    Keywords:
    Nuclear Structure
    Published by:
    http://www.aps.org/

    Latest Papers from Table of Contents or Articles in Press
  6. 6
    HOSHI, H. ; OHNO, I. ; HONMA, M. ; TANNO, Y. ; YAMAUCHI, K. ; TAMURA, G. ; SHIRATO, K.

    Oxford, UK : Blackwell Publishing Ltd
    Published 1995
    Staff View
    ISSN:
    1365-2222
    Source:
    Blackwell Publishing Journal Backfiles 1879-2005
    Topics:
    Medicine
    Notes:
    Background: Granulocyte-macrophage colony stimulating factor (GM-CSF) and inlerleukin (IL)-5 or IL-8 have been .suggested to play an important role in the pathogenesis of eosinophilic airway inflammation in bronchial asthma or neutrophilic airway inflammation in chronic bronchitis, respectively, However, GM-CSF and IL-8 have biological activities to either eosinophils or neutrophils.Objective: To investigate the contribution of these cytokines to airway inflammation, we compared the cellular differential and immunolocalization of GM-CSF, IL-5 and IL-8 in sputum cells from patients with bronchial asthma and chronic bronchitis.Methods: Cytospins of sputum cells from 12 patients with bronchial asthma and 12 with chronic bronchitis were subjected to cellular differential counting and immunocytochemistry with antihuman GM-CSF, IL-5 and IL-8 antibody.Results: The predominant cells in bronchial asthma were eosinophils and lymphocytes, while those in chronic bronchitis were neutrophils. All cytokines examined were detected in either bronchial asthma or chronic bronchitis, although the percentage of GM-CSF and IL-5 positive cells in bronchial asthma (53.4 ± 6.0 [mean±sfm]% and 9.7 ± 2.8%, respectively) was significantly higher than that in chronic bronchitis (11.4±2.5%; P 〈 0.001 and 1.7plusmn;0.3%; P 〈 0.007. respectively). In contrast, the percentage of IL-8 positive cells in chronic bronchitis (23.8 ± 7.0%) was significantly higher than that in bronchial asthma (7.7 ± 1.9%; P 〈 0.04). The cells positive for IL-5 were lymphocytes in bronchial asthma and chronic bronchitis. The cells positive for GM-CSF in bronchial asthma were predominantly eosinophils. while those in chronic bronchitis were monocytes/macrophages and neutrophils. In contrast, neutrophils are mainly positive for IL-8 in chronic bronchitis, while monocytes/macrophages and bronchial epithelial cells are positive for IL-8 in bronchial asthma.Conclusion: The immunochcmical comparison of GM-CSF and IL-8 localization in sputum cells between bronchial asthma chronic bronchitis suggests the differential regulation and roles of these cytokines in eosinophilic vs neutrophilic airway inflammation, resulting in the development of different types of airway inflammation.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1111/j.1365-2222.1995.tb00009.x

    Articles: DFG German National Licenses
  7. 7
    Staff View
    ISSN:
    0147-619X
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0147-619X(81)90040-8

    Articles: DFG German National Licenses
  8. 8
    Tanda, S. ; Ozeki, S. ; Honma, M. ; Ohi, A. ; Nakayama, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0921-4534
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0921-4534(91)91885-8

    Articles: DFG German National Licenses
  9. 9
    Hirano, T. ; Honma, M. ; Oka, K. ; Sakurai, E. ; Okochi, Y. ; Kozaki, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0009-8981
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0009-8981(87)90113-6

    Articles: DFG German National Licenses
  10. 10
    Honma, M. ; Hayami, Y.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0022-1996
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Economics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0022-1996(86)90064-4

    Articles: DFG German National Licenses
  11. 11
    Staff View
    ISSN:
    0027-5107
    Keywords:
    12-O-Tetradecanoylphorbol-13-acetate (TPA) ; 3-Methylcholanthrene (MCA) ; Cell transformation ; DNA fingerprinting ; DNA rearrangement
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0027-5107(94)90208-9

    Articles: DFG German National Licenses
  12. 12
    Staff View
    ISSN:
    0027-5107
    Keywords:
    In situ hybridization ; Micronuclei ; Mouse blood ; Mouse gamma satellite DNA
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0027-5107(94)90298-4

    Articles: DFG German National Licenses
  13. 13
    Staff View
    ISSN:
    0027-5107
    Keywords:
    DNA fingerprint ; Minisatellite DNA ; Mutagenicity testing ; Recombinational mutation
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0027-5107(93)90180-N

    Articles: DFG German National Licenses
  14. 14
    Staff View
    ISSN:
    0014-4827
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Medicine
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/S0014-4827(05)80080-1

    Articles: DFG German National Licenses
  15. 15
    Yao, M. ; Tanaka, I. ; Hikichi, K. ; Honma, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    1047-8477
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Biology
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1006/jsbi.1994.1060

    Articles: DFG German National Licenses
  16. 16
    Sagawa, H. ; Honma, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0370-2693(90)90224-T

    Articles: DFG German National Licenses
  17. 17
    Honma, M. ; Otsuka, T.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0370-2693(93)91313-C

    Articles: DFG German National Licenses
  18. 18
    Takaharu, O. ; Mizusaki, T. ; Honma, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0375-9474
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1016/0375-9474(94)90291-7

    Articles: DFG German National Licenses
  19. 19
    Otsuka, T. ; Honma, M.

    Amsterdam : Elsevier
    Staff View
    ISSN:
    0370-2693
    Source:
    Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics:
    Physics
    Type of Medium:
    Electronic Resource
    URL:
    http://linkinghub.elsevier.com/retrieve/pii/0370-2693(91)91581-F

    Articles: DFG German National Licenses
  20. 20
    Ishiyama, I. ; Yoshii, T. ; Honma, M. ; Mukaida, M. ; Yamaguchi, T.
    Springer
    Published 1988
    Staff View
    ISSN:
    1437-1596
    Keywords:
    DNA fingerprinting ; paternity determination ; DNA polymorphism ; DNS Fingerabdruck ; Vaterschaftsfeststellung ; DNS Polymorphismus
    Source:
    Springer Online Journal Archives 1860-2000
    Topics:
    Medicine
    Law
    Description / Table of Contents:
    Zusammenfassung Die genomischen Eigenschaften der Plazenta wurden mit Hilfe von einer Sonde “Myo” gegenüber dem Minisatellit, der im Bereich vom humanen Myoglobinen vorhanden ist, analysiert. Der DNS Fingerabdruck von Chorionzotten stimmt völlig mit dem des Fötus überein, während der Fingerabdruck der Dezidua die mütterliche Herkunft darstellt. Die Analyse von verschiedenen DNS Fingerabdrücken aus Fötus, Chorionzotten, Mutter und Vater bei einer künstlichen Schwangerschaftsunterbrechung hat gezeigt, daß der DNS Fingerabdruck von Chorionzotten, die gewöhnlich bei der klinischen Chorionzottenbiopsie entnommen werden können, die entscheidende Auskunft darüber gibt, das Bestehen der Vaterschaft vollständig zu beweisen.
    Notes:
    Summary Investigation of genomic polymorphisms detected by a minisatellite named tentatively “Myo”, which is expected to correspond to the minisatellite in human myoglobin gene of Jeffreys et al., gives distinct and different aspects of chorionic villus and the decidual membrane in the same placenta. The chorionic villus, which is regarded as the extraembryonal tissue, represents the essential embryonal DNA fingerprint pattern, while the decidual membrane reveals the maternal one. A comparison between the DNA fingerprints from the chorion villus and from the blood sample of the suspected father provides the possibility of setting a paternity determination which can be achieved during the first trimester of a pregnancy.
    Type of Medium:
    Electronic Resource
    URL:
    http://dx.doi.org/10.1007/BF00204434

    Articles: DFG German National Licenses