Search Results - (Author, Cooperation:M. Harland)
-
1Latest Papers from Table of Contents or Articles in PressE. A. Stepanov, S. Brener, F. Krien, M. Harland, A. I. Lichtenstein, and M. I. Katsnelson
American Physical Society (APS)
Published 2018Staff ViewPublication Date: 2018-07-21Publisher: American Physical Society (APS)Print ISSN: 0031-9007Electronic ISSN: 1079-7114Topics: PhysicsKeywords: Condensed Matter: Electronic Properties, etc.Published by: -
2Latest Papers from Table of Contents or Articles in PressS. Yokoyama ; S. L. Woods ; G. M. Boyle ; L. G. Aoude ; S. MacGregor ; V. Zismann ; M. Gartside ; A. E. Cust ; R. Haq ; M. Harland ; J. C. Taylor ; D. L. Duffy ; K. Holohan ; K. Dutton-Regester ; J. M. Palmer ; V. Bonazzi ; M. S. Stark ; J. Symmons ; M. H. Law ; C. Schmidt ; C. Lanagan ; L. O'Connor ; E. A. Holland ; H. Schmid ; J. A. Maskiell ; J. Jetann ; M. Ferguson ; M. A. Jenkins ; R. F. Kefford ; G. G. Giles ; B. K. Armstrong ; J. F. Aitken ; J. L. Hopper ; D. C. Whiteman ; P. D. Pharoah ; D. F. Easton ; A. M. Dunning ; J. A. Newton-Bishop ; G. W. Montgomery ; N. G. Martin ; G. J. Mann ; D. T. Bishop ; H. Tsao ; J. M. Trent ; D. E. Fisher ; N. K. Hayward ; K. M. Brown
Nature Publishing Group (NPG)
Published 2011Staff ViewPublication Date: 2011-11-15Publisher: Nature Publishing Group (NPG)Print ISSN: 0028-0836Electronic ISSN: 1476-4687Topics: BiologyChemistry and PharmacologyMedicineNatural Sciences in GeneralPhysicsKeywords: Adult ; Aged ; Aged, 80 and over ; Female ; Gene Expression Regulation, Neoplastic ; *Genetic Predisposition to Disease ; Humans ; Male ; Melanoma/*genetics ; Microphthalmia-Associated Transcription Factor/*genetics ; Middle Aged ; *Mutation ; Sumoylation/genetics ; Young AdultPublished by: -
3Latest Papers from Table of Contents or Articles in PressX. Huang ; J. C. McGann ; B. Y. Liu ; R. N. Hannoush ; J. R. Lill ; V. Pham ; K. Newton ; M. Kakunda ; J. Liu ; C. Yu ; S. G. Hymowitz ; J. A. Hongo ; A. Wynshaw-Boris ; P. Polakis ; R. M. Harland ; V. M. Dixit
American Association for the Advancement of Science (AAAS)
Published 2013Staff ViewPublication Date: 2013-02-02Publisher: American Association for the Advancement of Science (AAAS)Print ISSN: 0036-8075Electronic ISSN: 1095-9203Topics: BiologyChemistry and PharmacologyComputer ScienceMedicineNatural Sciences in GeneralPhysicsKeywords: Adaptor Proteins, Signal Transducing/*metabolism ; Animals ; Cell Line ; Cell Line, Tumor ; Cytosol/metabolism ; Female ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Low Density Lipoprotein Receptor-Related Protein-6/metabolism ; Neoplasm Transplantation ; Neoplasms/metabolism ; Ovarian Neoplasms/metabolism ; Phosphoproteins/*metabolism ; Phosphorylation ; Protein-Serine-Threonine Kinases/genetics/*metabolism ; Transplantation, Heterologous ; *Wnt Signaling Pathway ; Wnt3A Protein/metabolism ; Xenopus Proteins/genetics/*metabolism ; Xenopus laevis/embryology/metabolism ; beta Catenin/metabolismPublished by: -
4Articles: DFG German National LicensesBRENTNALL, S. J. ; BEERLING, D. J. ; OSBORNE, C. P. ; HARLAND, M. ; FRANCIS, J. E. ; VALDES, P. J. ; WITTIG, V. E.
Oxford, UK : Blackwell Science Ltd
Published 2005Staff ViewISSN: 1365-2486Source: Blackwell Publishing Journal Backfiles 1879-2005Topics: BiologyEnergy, Environment Protection, Nuclear Power EngineeringGeographyNotes: Polar forests once extended across the high-latitude landmasses during ice-free ‘greenhouse’ intervals in Earth history. In the Cretaceous ‘greenhouse’ world, Arctic conifer forests were considered predominantly deciduous, while those on Antarctica contained a significantly greater proportion of evergreens. To investigate the causes of this distinctive biogeographical pattern, we developed a coupled model of conifer growth, soil biogeochemistry and forest dynamics. Our approach emphasized general relationships between leaf lifespan (LL) and function, and incorporated the feedback of LL on soil nutrient status. The model was forced with a mid-Cretaceous ‘greenhouse’ climate simulated by the Hadley Centre GCM. Simulated polar forests contained mixtures of dominant LLs, which reproduced observed biogeographical patterns of deciduous, mixed and evergreen biomes. It emerged that disturbance by fire was a critical factor. Frequent fires in simulated Arctic ecosystems promoted the dominance of trees with short LLs that were characterized by the rapid growth and colonization rates typical of today's boreal pioneer species. In Antarctica, however, infrequent fires allowed trees with longer LLs to dominate because they attained greater height, despite slower growth rates. A direct test of the approach was successfully achieved by comparing modelled LLs with quantitative estimates using Cretaceous fossil woods from Svalbard in the European Arctic and Alexander Island, Antarctica. Observations and the model both revealed mixed Arctic and evergreen Antarctic communities with peak dominance of trees with the same LLs. Our study represents a significant departure from the long-held belief that leaf habit was an adaptation to warm, dark winter climates, and highlights a previously unrecognized role for disturbance (in whatever guise) in polar forest ecology.Type of Medium: Electronic ResourceURL: -
5Articles: DFG German National LicensesStaff View
ISSN: 0007-490XTopics: HistoryRomance StudiesNotes: REVIEWS OF BOOKSURL: -
6Articles: DFG German National LicensesStaff View
ISSN: 0007-490XTopics: HistoryRomance StudiesNotes: REVIEWS OF BOOKSURL: -
7Articles: DFG German National LicensesStaff View
ISSN: 0007-490XTopics: HistoryRomance StudiesNotes: REVIEWS OF BOOKSURL: -
8Articles: DFG German National LicensesStaff View
ISSN: 0007-490XTopics: HistoryRomance StudiesNotes: REVIEWS OF BOOKSURL: -
9Articles: DFG German National LicensesStaff View
ISSN: 0007-490XTopics: HistoryRomance StudiesNotes: REVIEWS OF BOOKSURL: -
10Articles: DFG German National LicensesStaff View
ISSN: 0007-490XTopics: HistoryRomance StudiesNotes: REVIEWS OF BOOKSURL: -
11Articles: DFG German National LicensesStaff View
ISSN: 0007-490XTopics: HistoryRomance StudiesNotes: REVIEWS OF BOOKSURL: -
12Articles: DFG German National LicensesStaff View
ISSN: 0007-490XTopics: HistoryRomance StudiesNotes: REVIEWS OF BOOKSURL: -
13Articles: DFG German National LicensesStaff View
ISSN: 1573-4919Keywords: non-selective cation channels ; TRP channels ; Xenopus laevis oocytes ; polyclonal antibody ; antisenseSource: Springer Online Journal Archives 1860-2000Topics: BiologyChemistry and PharmacologyMedicineNotes: Abstract The role of the TRP-1 protein, an animal cell homologue of the Drosophila transient receptor potential Ca2+ channel, in store-operated Ca2+ inflow in Xenopus laevis oocytes was investigated. A strategy involving RT-PCR and 3′ and 5′ rapid amplification of cDNA ends (RACE) was used to confirm and extend previous knowledge of the nucleotide and predicted amino acid sequences of Xenopus TRP-1 (xTRP-1). The predicted amino acid sequence was used to prepare an anti-TRP-1 polyclonal antibody which detected the endogenous oocyte xTRP-1 protein and the human TRPC-1 protein expressed in Xenopus oocytes. Ca2+ inflow (measured using fura-2) initiated by 3-deoxy-3-fluoroinositol 1,4,5-trisphosphate (InsP3F) or lysophosphatidic acid (LPA) was completely inhibited by low concentrations of lanthanides (IC50 = 0.5 μM), indicating that InsP3F and LPA principally activate store-operated Ca2+ channels (SOCs). Antisense cRNA or antisense oligodeoxynucleotides, based on different regions of the xTRP-1 cDNA sequence, when injected into Xenopus oocytes, did not inhibit InsP3F-, LPA- or thapsigargin-stimulated Ca2+ inflow. Oocytes expressing the hTRPC-1 protein, which is 96% similar to xTRP-1, exhibited no detectable enhancement of either basal or InsP3F-stimulated Ca2+ inflow and only a very small enhancement of LPA-stimulated Ca2+ inflow compared with control oocytes. It is concluded that the endogenous xTRP-1 protein is unlikely to be responsible for Ca2+ inflow through the previously-characterised Ca2+-specific SOCs which are found in Xenopus oocytes. It is considered that xTRP-1 is likely to be a receptor-activated non-selective cation channel such as the channel activated by maitotoxin.Type of Medium: Electronic ResourceURL: